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Volumn 21, Issue 2, 2018, Pages 163-173

Integrating new findings and examining clinical applications of pattern separation

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; LEVETIRACETAM; SEROTONIN UPTAKE INHIBITOR;

EID: 85040910469     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/s41593-017-0065-1     Document Type: Review
Times cited : (131)

References (146)
  • 1
    • 0032032006 scopus 로고    scopus 로고
    • Cognitive neuroscience and the study of memory
    • Milner, B., Squire, L. R. & Kandel, E. R. Cognitive neuroscience and the study of memory. Neuron 20, 445-468 (1998).
    • (1998) Neuron , vol.20 , pp. 445-468
    • Milner, B.1    Squire, L.R.2    Kandel, E.R.3
  • 3
    • 0015083717 scopus 로고
    • Simple memory: A theory for archicortex
    • Marr, D. Simple memory: a theory for archicortex. Phil. Trans. R. Soc. Lond. B 262, 23-81 (1971).
    • (1971) Phil. Trans. R. Soc. Lond.B , vol.262 , pp. 23-81
    • Marr, D.1
  • 4
    • 0028109694 scopus 로고
    • Computational analysis of the role of the hippocampus in memory
    • Treves, A. & Rolls, E. T. Computational analysis of the role of the hippocampus in memory. Hippocampus 4, 374-391 (1994).
    • (1994) Hippocampus , vol.4 , pp. 374-391
    • Treves, A.1    Rolls, E.T.2
  • 5
    • 0029340352 scopus 로고
    • Why there are complementary learning systems in the hippocampus and neocortex: Insights from the successes and failures of connectionist models of learning and memory
    • McClelland, J. L., McNaughton, B. L. & O'Reilly, R. C. Why there are complementary learning systems in the hippocampus and neocortex: insights from the successes and failures of connectionist models of learning and memory. Psychol. Rev. 102, 419-457 (1995).
    • (1995) Psychol. Rev , vol.102 , pp. 419-457
    • McClelland, J.L.1    McNaughton, B.L.2    O'Reilly, R.C.3
  • 6
    • 80053125086 scopus 로고    scopus 로고
    • Pattern separation in the hippocampus
    • Yassa, M. A. & Stark, C. E. Pattern separation in the hippocampus. Trends Neurosci. 34, 515-525 (2011).
    • (2011) Trends Neurosci , vol.34 , pp. 515-525
    • Yassa, M.A.1    Stark, C.E.2
  • 7
    • 0033817152 scopus 로고    scopus 로고
    • Hippocampal-neocortical interaction: A hierarchy of associativity
    • Lavenex, P. & Amaral, D. G. Hippocampal-neocortical interaction: a hierarchy of associativity. Hippocampus 10, 420-430 (2000).
    • (2000) Hippocampus , vol.10 , pp. 420-430
    • Lavenex, P.1    Amaral, D.G.2
  • 9
    • 84876687970 scopus 로고    scopus 로고
    • Selection of distinct populations of dentate granule cells in response to inputs as a mechanism for pattern separation in mice
    • Deng, W., Mayford, M. & Gage, F. H. Selection of distinct populations of dentate granule cells in response to inputs as a mechanism for pattern separation in mice. eLife 2, e00312 (2013).
    • (2013) ELife , vol.2 , pp. e00312
    • Deng, W.1    Mayford, M.2    Gage, F.H.3
  • 10
    • 85002368657 scopus 로고    scopus 로고
    • Dendrites of dentate gyrus granule cells contribute to pattern separation by controlling sparsity
    • Chavlis, S., Petrantonakis, P. C. & Poirazi, P. Dendrites of dentate gyrus granule cells contribute to pattern separation by controlling sparsity. Hippocampus 27, 89-110 (2017).
    • (2017) Hippocampus , vol.27 , pp. 89-110
    • Chavlis, S.1    Petrantonakis, P.C.2    Poirazi, P.3
  • 11
    • 84980021809 scopus 로고    scopus 로고
    • The enigmatic mossy cell of the dentate gyrus
    • Scharfman, H. E. The enigmatic mossy cell of the dentate gyrus. Nat. Rev. Neurosci. 17, 562-575 (2016).
    • (2016) Nat. Rev. Neurosci , vol.17 , pp. 562-575
    • Scharfman, H.E.1
  • 12
    • 85010917652 scopus 로고    scopus 로고
    • Spatial representations of granule cells and mossy cells of the dentate gyrus
    • GoodSmith, D. et al. Spatial representations of granule cells and mossy cells of the dentate gyrus. Neuron 93, 677-690.e5 (2017).
    • (2017) Neuron , vol.93 , pp. 677-677e5
    • GoodSmith, D.1
  • 13
    • 84962018702 scopus 로고    scopus 로고
    • Distinct contribution of adult-born hippocampal granule cells to context encoding
    • Danielson, N. B. et al. Distinct contribution of adult-born hippocampal granule cells to context encoding. Neuron 90, 101-112 (2016).
    • (2016) Neuron , vol.90 , pp. 101-112
    • Danielson, N.B.1
  • 14
    • 84991277135 scopus 로고    scopus 로고
    • Modulating neuronal competition dynamics in the dentate gyrus to rejuvenate aging memory circuits
    • McAvoy, K. M. et al. Modulating neuronal competition dynamics in the dentate gyrus to rejuvenate aging memory circuits. Neuron 91, 1356-1373 (2016).
    • (2016) Neuron , vol.91 , pp. 1356-1373
    • McAvoy, K.M.1
  • 15
    • 85011332604 scopus 로고    scopus 로고
    • Adult-born neurons modify excitatory synaptic transmission to existing neurons
    • Adlaf, E. W. et al. Adult-born neurons modify excitatory synaptic transmission to existing neurons. eLife 6, e19886 (2017).
    • (2017) ELife , vol.6 , pp. e19886
    • Adlaf, E.W.1
  • 16
    • 4344616877 scopus 로고    scopus 로고
    • Distinct ensemble codes in hippocampal areas CA3 and CA1
    • Leutgeb, S., Leutgeb, J. K., Treves, A., Moser, M.-B. & Moser, E. I. Distinct ensemble codes in hippocampal areas CA3 and CA1. Science 305, 1295-1298 (2004).
    • (2004) Science , vol.305 , pp. 1295-1298
    • Leutgeb, S.1    Leutgeb, J.K.2    Treves, A.3    Moser, M.-B.4    Moser, E.I.5
  • 17
    • 3242799836 scopus 로고    scopus 로고
    • Comparison of population coherence of place cells in hippocampal subfields CA1 and CA3
    • Lee, I., Yoganarasimha, D., Rao, G. & Knierim, J. J. Comparison of population coherence of place cells in hippocampal subfields CA1 and CA3. Nature 430, 456-459 (2004).
    • (2004) Nature , vol.430 , pp. 456-459
    • Lee, I.1    Yoganarasimha, D.2    Rao, G.3    Knierim, J.J.4
  • 18
    • 3242802723 scopus 로고    scopus 로고
    • Differences in hippocampal neuronal population responses to modifications of an environmental context: Evidence for distinct, yet complementary, functions of CA3 and CA1 ensembles
    • Vazdarjanova, A. & Guzowski, J. F. Differences in hippocampal neuronal population responses to modifications of an environmental context: evidence for distinct, yet complementary, functions of CA3 and CA1 ensembles. J. Neurosci. 24, 6489-6496 (2004).
    • (2004) J. Neurosci , vol.24 , pp. 6489-6496
    • Vazdarjanova, A.1    Guzowski, J.F.2
  • 19
    • 8844235057 scopus 로고    scopus 로고
    • Ensemble dynamics of hippocampal regions CA3 and CA1
    • Guzowski, J. F., Knierim, J. J. & Moser, E. I. Ensemble dynamics of hippocampal regions CA3 and CA1. Neuron 44, 581-584 (2004).
    • (2004) Neuron , vol.44 , pp. 581-584
    • Guzowski, J.F.1    Knierim, J.J.2    Moser, E.I.3
  • 20
    • 78650994901 scopus 로고    scopus 로고
    • Distinct pattern separation related transfer functions in human CA3/dentate and CA1 revealed using high-resolution fMRI and variable mnemonic similarity
    • Lacy, J. W., Yassa, M. A., Stark, S. M., Muftuler, L. T. & Stark, C. E. Distinct pattern separation related transfer functions in human CA3/dentate and CA1 revealed using high-resolution fMRI and variable mnemonic similarity. Learn. Mem. 18, 15-18 (2010).
    • (2010) Learn. Mem , vol.18 , pp. 15-18
    • Lacy, J.W.1    Yassa, M.A.2    Stark, S.M.3    Muftuler, L.T.4    Stark, C.E.5
  • 21
    • 84922141469 scopus 로고    scopus 로고
    • Complementary roles of human hippocampal subfields in differentiation and integration of spatial context
    • Stokes, J., Kyle, C. & Ekstrom, A. D. Complementary roles of human hippocampal subfields in differentiation and integration of spatial context. J. Cogn. Neurosci 27, 546-559 (2015).
    • (2015) J. Cogn. Neurosci , vol.27 , pp. 546-559
    • Stokes, J.1    Kyle, C.2    Ekstrom, A.D.3
  • 22
    • 26944445796 scopus 로고    scopus 로고
    • Progressive transformation of hippocampal neuronal representations in "morphed" environments
    • Leutgeb, J. K. et al. Progressive transformation of hippocampal neuronal representations in "morphed" environments. Neuron 48, 345-358 (2005).
    • (2005) Neuron , vol.48 , pp. 345-358
    • Leutgeb, J.K.1
  • 23
    • 84857226538 scopus 로고    scopus 로고
    • Evidence for area CA1 as a match/mismatch detector: A high-resolution fMRI study of the human hippocampus
    • Duncan, K., Ketz, N., Inati, S. J. & Davachi, L. Evidence for area CA1 as a match/mismatch detector: a high-resolution fMRI study of the human hippocampus. Hippocampus 22, 389-398 (2012).
    • (2012) Hippocampus , vol.22 , pp. 389-398
    • Duncan, K.1    Ketz, N.2    Inati, S.J.3    Davachi, L.4
  • 24
    • 0028302804 scopus 로고
    • Laminar selectivity of the cholinergic suppression of synaptic transmission in rat hippocampal region CA1: Computational modeling and brain slice physiology
    • Hasselmo, M. E. & Schnell, E. Laminar selectivity of the cholinergic suppression of synaptic transmission in rat hippocampal region CA1: computational modeling and brain slice physiology. J. Neurosci. 14, 3898-3914 (1994).
    • (1994) J. Neurosci , vol.14 , pp. 3898-3914
    • Hasselmo, M.E.1    Schnell, E.2
  • 25
    • 33845482744 scopus 로고    scopus 로고
    • An unexpected sequence of events: Mismatch detection in the human hippocampus
    • Kumaran, D. & Maguire, E. A. An unexpected sequence of events: mismatch detection in the human hippocampus. PLoS Biol. 4, e424 (2006).
    • (2006) PLoS Biol , vol.4 , pp. e424
    • Kumaran, D.1    Maguire, E.A.2
  • 26
    • 34547903594 scopus 로고    scopus 로고
    • Match mismatch processes underlie human hippocampal responses to associative novelty
    • Kumaran, D. & Maguire, E. A. Match mismatch processes underlie human hippocampal responses to associative novelty. J. Neurosci. 27, 8517-8524 (2007).
    • (2007) J. Neurosci , vol.27 , pp. 8517-8524
    • Kumaran, D.1    Maguire, E.A.2
  • 27
    • 34547921374 scopus 로고    scopus 로고
    • Which computational mechanisms operate in the hippocampus during novelty detection?
    • Kumaran, D. & Maguire, E. A. Which computational mechanisms operate in the hippocampus during novelty detection? Hippocampus 17, 735-748 (2007).
    • (2007) Hippocampus , vol.17 , pp. 735-748
    • Kumaran, D.1    Maguire, E.A.2
  • 28
    • 19544370227 scopus 로고    scopus 로고
    • The hippocampal-VTA loop: Controlling the entry of information into long-term memory
    • Lisman, J. E. & Grace, A. A. The hippocampal-VTA loop: controlling the entry of information into long-term memory. Neuron 46, 703-713 (2005).
    • (2005) Neuron , vol.46 , pp. 703-713
    • Lisman, J.E.1    Grace, A.A.2
  • 29
    • 4544324168 scopus 로고    scopus 로고
    • Mode shifting between storage and recall based on novelty detection in oscillating hippocampal circuits
    • Meeter, M., Murre, J. M. J. & Talamini, L. M. Mode shifting between storage and recall based on novelty detection in oscillating hippocampal circuits. Hippocampus 14, 722-741 (2004).
    • (2004) Hippocampus , vol.14 , pp. 722-741
    • Meeter, M.1    Murre, J.M.J.2    Talamini, L.M.3
  • 30
    • 33847149696 scopus 로고    scopus 로고
    • Pattern separation in the dentate gyrus and CA3 of the hippocampus
    • Leutgeb, J. K., Leutgeb, S., Moser, M.-B. & Moser, E. I. Pattern separation in the dentate gyrus and CA3 of the hippocampus. Science 315, 961-966 (2007).
    • (2007) Science , vol.315 , pp. 961-966
    • Leutgeb, J.K.1    Leutgeb, S.2    Moser, M.-B.3    Moser, E.I.4
  • 31
    • 84892687827 scopus 로고    scopus 로고
    • CA3 retrieves coherent representations from degraded input: Direct evidence for CA3 pattern completion and dentate gyrus pattern separation
    • Neunuebel, J. P. & Knierim, J. J. CA3 retrieves coherent representations from degraded input: direct evidence for CA3 pattern completion and dentate gyrus pattern separation. Neuron 81, 416-427 (2014).
    • (2014) Neuron , vol.81 , pp. 416-427
    • Neunuebel, J.P.1    Knierim, J.J.2
  • 32
    • 0023620017 scopus 로고
    • Hippocampal synaptic enhancement and information storage within a distributed memory system
    • McNaughton, B. L. & Morris, R. G. M. Hippocampal synaptic enhancement and information storage within a distributed memory system. Trends Neurosci. 10, 408-415 (1987).
    • (1987) Trends Neurosci , vol.10 , pp. 408-415
    • McNaughton, B.L.1    Morris, R.G.M.2
  • 33
    • 34548839628 scopus 로고    scopus 로고
    • Overcoming interference: An fMRI investigation of pattern separation in the medial temporal lobe
    • Kirwan, C. B. & Stark, C. E. L. Overcoming interference: an fMRI investigation of pattern separation in the medial temporal lobe. Learn. Mem. 14, 625-633 (2007).
    • (2007) Learn. Mem , vol.14 , pp. 625-633
    • Kirwan, C.B.1    Stark, C.E.L.2
  • 34
    • 84885951316 scopus 로고    scopus 로고
    • A task to assess behavioral pattern separation (BPS) in humans: Data from healthy aging and mild cognitive impairment
    • Stark, S. M., Yassa, Ma, Lacy, J. W. & Stark, C. E. L. A task to assess behavioral pattern separation (BPS) in humans: Data from healthy aging and mild cognitive impairment. Neuropsychologia 51, 2442-2449 (2013).
    • (2013) Neuropsychologia , vol.51 , pp. 2442-2449
    • Stark, S.M.1    Ma, Y.2    Lacy, J.W.3    Stark, C.E.L.4
  • 35
    • 80051937468 scopus 로고    scopus 로고
    • Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults
    • Yassa, M. A. et al. Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults. Hippocampus 21, 968-979 (2011).
    • (2011) Hippocampus , vol.21 , pp. 968-979
    • Yassa, M.A.1
  • 36
    • 77952422876 scopus 로고    scopus 로고
    • High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic mild cognitive impairment
    • Yassa, M. A. et al. High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic mild cognitive impairment. Neuroimage 51, 1242-1252 (2010).
    • (2010) Neuroimage , vol.51 , pp. 1242-1252
    • Yassa, M.A.1
  • 37
    • 66149091970 scopus 로고    scopus 로고
    • Visual object pattern separation deficits in nondemented older adults
    • Toner, C. K., Pirogovsky, E., Kirwan, C. B. & Gilbert, P. E. Visual object pattern separation deficits in nondemented older adults. Learn. Mem. 16, 338-342 (2009).
    • (2009) Learn. Mem , vol.16 , pp. 338-342
    • Toner, C.K.1    Pirogovsky, E.2    Kirwan, C.B.3    Gilbert, P.E.4
  • 39
    • 84907691911 scopus 로고    scopus 로고
    • Object and spatial mnemonic interference differentially engage lateral and medial entorhinal cortex in humans
    • Reagh, Z. M. & Yassa, M. A. Object and spatial mnemonic interference differentially engage lateral and medial entorhinal cortex in humans. Proc. Natl. Acad. Sci. USA 111, E4264-E4273 (2014).
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. E4264-E4273
    • Reagh, Z.M.1    Yassa, M.A.2
  • 40
    • 77953054528 scopus 로고    scopus 로고
    • Individual differences in spatial pattern separation performance associated with healthy aging in humans
    • Stark, S. M., Yassa, M. A. & Stark, C. E. L. Individual differences in spatial pattern separation performance associated with healthy aging in humans. Learn. Mem. 17, 284-288 (2010).
    • (2010) Learn. Mem , vol.17 , pp. 284-288
    • Stark, S.M.1    Yassa, M.A.2    Stark, C.E.L.3
  • 41
    • 84865577239 scopus 로고    scopus 로고
    • Spatial pattern separation in cognitively normal young and older adults
    • Holden, H. M., Hoebel, C., Loftis, K. & Gilbert, P. E. Spatial pattern separation in cognitively normal young and older adults. Hippocampus 22, 1826-1832 (2012).
    • (2012) Hippocampus , vol.22 , pp. 1826-1832
    • Holden, H.M.1    Hoebel, C.2    Loftis, K.3    Gilbert, P.E.4
  • 42
    • 84862741813 scopus 로고    scopus 로고
    • Less efficient pattern separation may contribute to age-related spatial memory deficits
    • Holden, H. M. & Gilbert, P. E. Less efficient pattern separation may contribute to age-related spatial memory deficits. Front. Aging Neurosci. 4, 9 (2012).
    • (2012) Front. Aging Neurosci , vol.4 , pp. 9
    • Holden, H.M.1    Gilbert, P.E.2
  • 43
    • 84893957687 scopus 로고    scopus 로고
    • Spatial discrimination deficits as a function of mnemonic interference in aged adults with and without memory impairment
    • Reagh, Z. M. et al. Spatial discrimination deficits as a function of mnemonic interference in aged adults with and without memory impairment. Hippocampus 24, 303-314 (2014).
    • (2014) Hippocampus , vol.24 , pp. 303-314
    • Reagh, Z.M.1
  • 44
    • 0031962068 scopus 로고    scopus 로고
    • Memory for spatial location: Role of the hippocampus in mediating spatial pattern separation
    • Gilbert, P. E., Kesner, R. P. & DeCoteau, W. E. Memory for spatial location: role of the hippocampus in mediating spatial pattern separation. J. Neurosci. 18, 804-810 (1998).
    • (1998) J. Neurosci , vol.18 , pp. 804-810
    • Gilbert, P.E.1    Kesner, R.P.2    DeCoteau, W.E.3
  • 45
    • 84885005379 scopus 로고    scopus 로고
    • The touchscreen operant platform for testing working memory and pattern separation in rats and mice
    • Oomen, C. A. et al. The touchscreen operant platform for testing working memory and pattern separation in rats and mice. Nat. Protoc. 8, 2006-2021 (2013).
    • (2013) Nat. Protoc , vol.8 , pp. 2006-2021
    • Oomen, C.A.1
  • 46
    • 67549096690 scopus 로고    scopus 로고
    • A new touchscreen test of pattern separation: Effect of hippocampal lesions
    • McTighe, S. M., Mar, A. C., Romberg, C., Bussey, T. J. & Saksida, L. M. A new touchscreen test of pattern separation: effect of hippocampal lesions. Neuroreport 20, 881-885 (2009).
    • (2009) Neuroreport , vol.20 , pp. 881-885
    • McTighe, S.M.1    Mar, A.C.2    Romberg, C.3    Bussey, T.J.4    Saksida, L.M.5
  • 47
    • 84862697647 scopus 로고    scopus 로고
    • The effect of interference on temporal order memory for random and fixed sequences in nondemented older adults
    • Tolentino, J. C., Pirogovsky, E., Luu, T., Toner, C. K. & Gilbert, P. E. The effect of interference on temporal order memory for random and fixed sequences in nondemented older adults. Learn. Mem. 19, 251-255 (2012).
    • (2012) Learn. Mem , vol.19 , pp. 251-255
    • Tolentino, J.C.1    Pirogovsky, E.2    Luu, T.3    Toner, C.K.4    Gilbert, P.E.5
  • 48
    • 84927567128 scopus 로고    scopus 로고
    • Temporal discrimination deficits as a function of lag interference in older adults
    • Roberts, J. M., Ly, M., Murray, E. & Yassa, M. A. Temporal discrimination deficits as a function of lag interference in older adults. Hippocampus 24, 1189-1196 (2014).
    • (2014) Hippocampus , vol.24 , pp. 1189-1196
    • Roberts, J.M.1    Ly, M.2    Murray, E.3    Yassa, M.A.4
  • 49
    • 0035689480 scopus 로고    scopus 로고
    • Dissociating hippocampal subregions: Double dissociation between dentate gyrus and CA1
    • Gilbert, P. E., Kesner, R. P. & Lee, I. Dissociating hippocampal subregions: double dissociation between dentate gyrus and CA1. Hippocampus 11, 626-636 (2001).
    • (2001) Hippocampus , vol.11 , pp. 626-636
    • Gilbert, P.E.1    Kesner, R.P.2    Lee, I.3
  • 50
    • 0036351173 scopus 로고    scopus 로고
    • The amygdala but not the hippocampus is involved in pattern separation based on reward value
    • Gilbert, P. E. & Kesner, R. P. The amygdala but not the hippocampus is involved in pattern separation based on reward value. Neurobiol. Learn. Mem. 77, 338-353 (2002).
    • (2002) Neurobiol. Learn. Mem , vol.77 , pp. 338-353
    • Gilbert, P.E.1    Kesner, R.P.2
  • 51
    • 84906790522 scopus 로고    scopus 로고
    • Pattern separation of emotional information in hippocampal dentate and CA3
    • Leal, S. L., Tighe, S. K., Jones, C. K. & Yassa, M. A. Pattern separation of emotional information in hippocampal dentate and CA3. Hippocampus 24, 1146-1155 (2014).
    • (2014) Hippocampus , vol.24 , pp. 1146-1155
    • Leal, S.L.1    Tighe, S.K.2    Jones, C.K.3    Yassa, M.A.4
  • 52
    • 84897047721 scopus 로고    scopus 로고
    • Asymmetric effects of emotion on mnemonic interference
    • Leal, S. L., Tighe, S. K. & Yassa, M. A. Asymmetric effects of emotion on mnemonic interference. Neurobiol. Learn. Mem. 111, 41-48 (2014).
    • (2014) Neurobiol. Learn. Mem , vol.111 , pp. 41-48
    • Leal, S.L.1    Tighe, S.K.2    Yassa, M.A.3
  • 53
    • 41149088380 scopus 로고    scopus 로고
    • Pattern separation in the human hippocampal CA3 and dentate gyrus
    • Bakker, A., Kirwan, C. B., Miller, M. & Stark, C. E. L. Pattern separation in the human hippocampal CA3 and dentate gyrus. Science 319, 1640-1642 (2008).
    • (2008) Science , vol.319 , pp. 1640-1642
    • Bakker, A.1    Kirwan, C.B.2    Miller, M.3    Stark, C.E.L.4
  • 54
    • 30044437340 scopus 로고    scopus 로고
    • Repetition and the brain: Neural models of stimulus-specific effects
    • Grill-Spector, K., Henson, R. & Martin, A. Repetition and the brain: neural models of stimulus-specific effects. Trends Cogn. Sci. 10, 14-23 (2006).
    • (2006) Trends Cogn. Sci , vol.10 , pp. 14-23
    • Grill-Spector, K.1    Henson, R.2    Martin, A.3
  • 55
    • 58749086002 scopus 로고    scopus 로고
    • Novelty signals: A window into hippocampal information processing
    • Kumaran, D. & Maguire, E. A. Novelty signals: a window into hippocampal information processing. Trends Cogn. Sci. 13, 47-54 (2009).
    • (2009) Trends Cogn. Sci , vol.13 , pp. 47-54
    • Kumaran, D.1    Maguire, E.A.2
  • 56
    • 84952899838 scopus 로고    scopus 로고
    • Successful retrieval of competing spatial environments in humans involves hippocampal pattern separation mechanisms
    • Kyle, C. T., Stokes, J. D., Lieberman, J. S., Hassan, A. S. & Ekstrom, A. D. Successful retrieval of competing spatial environments in humans involves hippocampal pattern separation mechanisms. eLife 4, 415-445 (2015).
    • (2015) ELife , vol.4 , pp. 415-445
    • Kyle, C.T.1    Stokes, J.D.2    Lieberman, J.S.3    Hassan, A.S.4    Ekstrom, A.D.5
  • 57
    • 84978657131 scopus 로고    scopus 로고
    • Strong evidence for pattern separation in human dentate gyrus
    • Berron, D. et al. Strong evidence for pattern separation in human dentate gyrus. J. Neurosci. 36, 7569-7579 (2016).
    • (2016) J. Neurosci , vol.36 , pp. 7569-7579
    • Berron, D.1
  • 58
    • 84992189583 scopus 로고    scopus 로고
    • The human dentate gyrus plays a necessary role in discriminating new memories
    • Baker, S. et al. The human dentate gyrus plays a necessary role in discriminating new memories. Curr. Biol. 26, 2629-2634 (2016).
    • (2016) Curr. Biol , vol.26 , pp. 2629-2634
    • Baker, S.1
  • 59
  • 60
    • 84960309242 scopus 로고    scopus 로고
    • Tracking the flow of hippocampal computation: Pattern separation, pattern completion, and attractor dynamics
    • Knierim, J. J. & Neunuebel, J. P. Tracking the flow of hippocampal computation: Pattern separation, pattern completion, and attractor dynamics. Neurobiol. Learn. Mem. 129, 38-49 (2016).
    • (2016) Neurobiol. Learn. Mem , vol.129 , pp. 38-49
    • Knierim, J.J.1    Neunuebel, J.P.2
  • 61
    • 84906921314 scopus 로고    scopus 로고
    • Functional correlates of the lateral and medial entorhinal cortex: Objects, path integration and local-global reference frames
    • Knierim, J. J., Neunuebel, J. P. & Deshmukh, S. S. Functional correlates of the lateral and medial entorhinal cortex: objects, path integration and local-global reference frames. Phil. Trans. R. Soc. Lond. B 369, 20130369 (2013).
    • (2013) Phil. Trans. R. Soc. Lond.B , vol.369 , pp. 20130369
    • Knierim, J.J.1    Neunuebel, J.P.2    Deshmukh, S.S.3
  • 62
    • 84968431724 scopus 로고    scopus 로고
    • The representational-hierarchical view of pattern separation: Not just hippocampus, not just space, not just memory? Neurobiol
    • Kent, B. A., Hvoslef-Eide, M., Saksida, L. M. & Bussey, T. J. The representational-hierarchical view of pattern separation: Not just hippocampus, not just space, not just memory? Neurobiol. Learn. Mem. 129, 99-106 (2016).
    • (2016) Learn. Mem , vol.129 , pp. 99-106
    • Kent, B.A.1    Hvoslef-Eide, M.2    Saksida, L.M.3    Bussey, T.J.4
  • 63
    • 84961989806 scopus 로고    scopus 로고
    • Cortical pattern separation and item-specific memory encoding
    • Pidgeon, L. M. & Morcom, A. M. Cortical pattern separation and item-specific memory encoding. Neuropsychologia 85, 256-271 (2016).
    • (2016) Neuropsychologia , vol.85 , pp. 256-271
    • Pidgeon, L.M.1    Morcom, A.M.2
  • 64
    • 85007578435 scopus 로고    scopus 로고
    • Repetition reveals ups and downs of hippocampal, thalamic, and neocortical engagement during mnemonic decisions
    • Reagh, Z. M., Murray, E. A. & Yassa, M. A. Repetition reveals ups and downs of hippocampal, thalamic, and neocortical engagement during mnemonic decisions. Hippocampus 27, 169-183 (2016).
    • (2016) Hippocampus , vol.27 , pp. 169-183
    • Reagh, Z.M.1    Murray, E.A.2    Yassa, M.A.3
  • 65
    • 0035849892 scopus 로고    scopus 로고
    • Neurophysiological investigation of the basis of the fMRI signal
    • Logothetis, N. K., Pauls, J., Augath, M., Trinath, T. & Oeltermann, A. Neurophysiological investigation of the basis of the fMRI signal. Nature 412, 150-157 (2001).
    • (2001) Nature , vol.412 , pp. 150-157
    • Logothetis, N.K.1    Pauls, J.2    Augath, M.3    Trinath, T.4    Oeltermann, A.5
  • 66
    • 77149144137 scopus 로고    scopus 로고
    • How and when the fMRI BOLD signal relates to underlying neural activity: The danger in dissociation
    • Ekstrom, A. How and when the fMRI BOLD signal relates to underlying neural activity: the danger in dissociation. Brain Res. Rev. 62, 233-244 (2010).
    • (2010) Brain Res. Rev , vol.62 , pp. 233-244
    • Ekstrom, A.1
  • 67
    • 84905911238 scopus 로고    scopus 로고
    • Brain-state dependent uncoupling of BOLD and local field potentials in laminar olfactory bulb
    • Gong, L., Li, B., Wu, R., Li, A. & Xu, F. Brain-state dependent uncoupling of BOLD and local field potentials in laminar olfactory bulb. Neurosci. Lett. 580, 1-6 (2014).
    • (2014) Neurosci. Lett , vol.580 , pp. 1-6
    • Gong, L.1    Li, B.2    Wu, R.3    Li, A.4    Xu, F.5
  • 68
    • 84954527977 scopus 로고    scopus 로고
    • Analysis of neural-BOLD coupling through four models of the neural metabolic demand
    • Tyler, C. W., Likova, L. T. & Nicholas, S. C. Analysis of neural-BOLD coupling through four models of the neural metabolic demand. Front. Neurosci. 9, 419 (2015).
    • (2015) Front. Neurosci , vol.9 , pp. 419
    • Tyler, C.W.1    Likova, L.T.2    Nicholas, S.C.3
  • 69
    • 84955112947 scopus 로고
    • Age differences in memory: The roles of attention and depth of processing
    • (eds. Poon, L. W., Fozard, J., Cermak, L. S., Arenberg, D. & Thompson, L. W.), (Psychology Press, New York
    • Craik, F. I. M. & Simon, E. Age differences in memory: the roles of attention and depth of processing. in New Directions in Memory and Aging (eds. Poon, L. W., Fozard, J., Cermak, L. S., Arenberg, D. & Thompson, L. W.) 95-112 (Psychology Press, New York, 1980).
    • (1980) New Directions in Memory and Aging , pp. 95-112
    • Craik, F.I.M.1    Simon, E.2
  • 70
    • 54049149226 scopus 로고    scopus 로고
    • Changes in cognitive function in human aging
    • (ed. Riddle, D.), CRC Press, Boca Raton, FL, USA
    • Glisky, E. Changes in cognitive function in human aging. in Brain Aging: Models, Methods, and Mechanisms (ed. Riddle, D.) 1-10 (CRC Press, Boca Raton, FL, USA, 2007).
    • (2007) Brain Aging: Models, Methods, and Mechanisms , pp. 1-10
    • Glisky, E.1
  • 71
    • 84947447858 scopus 로고    scopus 로고
    • Neurocognitive aging and the hippocampus across species
    • Leal, S. L. & Yassa, M. A. Neurocognitive aging and the hippocampus across species. Trends Neurosci. 38, 800-812 (2015).
    • (2015) Trends Neurosci , vol.38 , pp. 800-812
    • Leal, S.L.1    Yassa, M.A.2
  • 72
    • 33751178775 scopus 로고    scopus 로고
    • Neurocognitive aging: Prior memories hinder new hippocampal encoding
    • Wilson, I. A., Gallagher, M., Eichenbaum, H. & Tanila, H. Neurocognitive aging: prior memories hinder new hippocampal encoding. Trends Neurosci. 29, 662-670 (2006).
    • (2006) Trends Neurosci , vol.29 , pp. 662-670
    • Wilson, I.A.1    Gallagher, M.2    Eichenbaum, H.3    Tanila, H.4
  • 73
    • 33845895544 scopus 로고    scopus 로고
    • Individual differences in neurocognitive aging of the medial temporal lobe
    • Gallagher, M. et al. Individual differences in neurocognitive aging of the medial temporal lobe. Age 28, 221-233 (2006).
    • (2006) Age , vol.28 , pp. 221-233
    • Gallagher, M.1
  • 74
    • 84860659903 scopus 로고    scopus 로고
    • Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment
    • Bakker, A. et al. Reduction of hippocampal hyperactivity improves cognition in amnestic mild cognitive impairment. Neuron 74, 467-474 (2012).
    • (2012) Neuron , vol.74 , pp. 467-474
    • Bakker, A.1
  • 75
    • 22544475288 scopus 로고    scopus 로고
    • Age-associated alterations of hippocampal place cells are subregion specific
    • Wilson, I. A., Ikonen, S., Gallagher, M., Eichenbaum, H. & Tanila, H. Age-associated alterations of hippocampal place cells are subregion specific. J. Neurosci. 25, 6877-6886 (2005).
    • (2005) J. Neurosci , vol.25 , pp. 6877-6886
    • Wilson, I.A.1    Ikonen, S.2    Gallagher, M.3    Eichenbaum, H.4    Tanila, H.5
  • 76
    • 85026626924 scopus 로고    scopus 로고
    • Age-related changes in lateral entorhinal and CA3 neuron allocation predict poor performance on object discrimination
    • Maurer, A. P. et al. Age-related changes in lateral entorhinal and CA3 neuron allocation predict poor performance on object discrimination. Front. Syst. Neurosci. 11, 49 (2017).
    • (2017) Front. Syst. Neurosci , vol.11 , pp. 49
    • Maurer, A.P.1
  • 77
    • 1942521679 scopus 로고    scopus 로고
    • Cognitive aging and the hippocampus: How old rats represent new environments
    • Wilson, I. A. et al. Cognitive aging and the hippocampus: how old rats represent new environments. J. Neurosci. 24, 3870-3878 (2004).
    • (2004) J. Neurosci , vol.24 , pp. 3870-3878
    • Wilson, I.A.1
  • 78
    • 33645737543 scopus 로고    scopus 로고
    • Examining the gateway to the limbic system with diffusion tensor imaging: The perforant pathway in dementia
    • Kalus, P. et al. Examining the gateway to the limbic system with diffusion tensor imaging: the perforant pathway in dementia. Neuroimage 30, 713-720 (2006).
    • (2006) Neuroimage , vol.30 , pp. 713-720
    • Kalus, P.1
  • 79
    • 77955440429 scopus 로고    scopus 로고
    • Ultrahigh-resolution microstructural diffusion tensor imaging reveals perforant path degradation in aged humans in vivo
    • Yassa, M. A., Muftuler, L. T. & Stark, C. E. Ultrahigh-resolution microstructural diffusion tensor imaging reveals perforant path degradation in aged humans in vivo. Proc. Natl. Acad. Sci. USA 107, 12687-12691 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 12687-12691
    • Yassa, M.A.1    Muftuler, L.T.2    Stark, C.E.3
  • 80
    • 0034282068 scopus 로고    scopus 로고
    • LTP induction threshold change in old rats at the perforant path-granule cell synapse
    • Barnes, C. A., Rao, G. & Houston, F. P. LTP induction threshold change in old rats at the perforant path-granule cell synapse. Neurobiol. Aging 21, 613-620 (2000).
    • (2000) Neurobiol. Aging , vol.21 , pp. 613-620
    • Barnes, C.A.1    Rao, G.2    Houston, F.P.3
  • 81
    • 0034279244 scopus 로고    scopus 로고
    • Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats
    • Smith, T. D., Adams, M. M., Gallagher, M., Morrison, J. H. & Rapp, P. R. Circuit-specific alterations in hippocampal synaptophysin immunoreactivity predict spatial learning impairment in aged rats. J. Neurosci. 20, 6587-6593 (2000).
    • (2000) J. Neurosci , vol.20 , pp. 6587-6593
    • Smith, T.D.1    Adams, M.M.2    Gallagher, M.3    Morrison, J.H.4    Rapp, P.R.5
  • 82
    • 84883004035 scopus 로고    scopus 로고
    • Hilar interneuron vulnerability distinguishes aged rats with memory impairment
    • Spiegel, A. M., Koh, M. T., Vogt, N. M., Rapp, P. R. & Gallagher, M. Hilar interneuron vulnerability distinguishes aged rats with memory impairment. J. Comp. Neurol. 521, 3508-3523 (2013).
    • (2013) J. Comp. Neurol , vol.521 , pp. 3508-3523
    • Spiegel, A.M.1    Koh, M.T.2    Vogt, N.M.3    Rapp, P.R.4    Gallagher, M.5
  • 83
    • 23244445918 scopus 로고    scopus 로고
    • Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD
    • Dickerson, B. C. et al. Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD. Neurology 65, 404-411 (2005).
    • (2005) Neurology , vol.65 , pp. 404-411
    • Dickerson, B.C.1
  • 84
    • 0032951044 scopus 로고    scopus 로고
    • Differential regional dysfunction of the hippocampal formation among elderly with memory decline and Alzheimer's disease
    • Small, S. A., Perera, G. M., DeLaPaz, R., Mayeux, R. & Stern, Y. Differential regional dysfunction of the hippocampal formation among elderly with memory decline and Alzheimer's disease. Ann. Neurol. 45, 466-472 (1999).
    • (1999) Ann. Neurol , vol.45 , pp. 466-472
    • Small, S.A.1    Perera, G.M.2    DeLaPaz, R.3    Mayeux, R.4    Stern, Y.5
  • 86
    • 0029821150 scopus 로고    scopus 로고
    • Preserved neuron number in the hippocampus of aged rats with spatial learning deficits
    • Rapp, P. R. & Gallagher, M. Preserved neuron number in the hippocampus of aged rats with spatial learning deficits. Proc. Natl. Acad. Sci. USA 93, 9926-9930 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9926-9930
    • Rapp, P.R.1    Gallagher, M.2
  • 87
    • 2942572946 scopus 로고    scopus 로고
    • Relationship between hippocampal volume and memory ability in healthy individuals across the lifespan: Review and meta-analysis
    • Van Petten, C. Relationship between hippocampal volume and memory ability in healthy individuals across the lifespan: review and meta-analysis. Neuropsychologia 42, 1394-1413 (2004).
    • (2004) Neuropsychologia , vol.42 , pp. 1394-1413
    • Van Petten, C.1
  • 88
    • 84924615179 scopus 로고    scopus 로고
    • Effects of aging on mnemonic discrimination of emotional information
    • Leal, S. L. & Yassa, M. A. Effects of aging on mnemonic discrimination of emotional information. Behav. Neurosci. 128, 539-547 (2014).
    • (2014) Behav. Neurosci , vol.128 , pp. 539-547
    • Leal, S.L.1    Yassa, M.A.2
  • 89
    • 84991594444 scopus 로고    scopus 로고
    • Age-related individual variability in memory performance is associated with amygdalahippocampal circuit function and emotional pattern separation
    • Leal, S. L., Noche, J. A., Murray, E. A. & Yassa, M. A. Age-related individual variability in memory performance is associated with amygdalahippocampal circuit function and emotional pattern separation. Neurobiol. Aging 49, 9-19 (2017).
    • (2017) Neurobiol. Aging , vol.49 , pp. 9-19
    • Leal, S.L.1    Noche, J.A.2    Murray, E.A.3    Yassa, M.A.4
  • 90
    • 24644439189 scopus 로고    scopus 로고
    • Sparing of the familiarity component of recognition memory in a patient with hippocampal pathology
    • Aggleton, J. P. et al. Sparing of the familiarity component of recognition memory in a patient with hippocampal pathology. Neuropsychologia 43, 1810-1823 (2005).
    • (2005) Neuropsychologia , vol.43 , pp. 1810-1823
    • Aggleton, J.P.1
  • 91
    • 84961217517 scopus 로고    scopus 로고
    • Greater loss of object than spatial mnemonic discrimination in aged adults
    • Reagh, Z. M. et al. Greater loss of object than spatial mnemonic discrimination in aged adults. Hippocampus 26, 417-422 (2016).
    • (2016) Hippocampus , vol.26 , pp. 417-422
    • Reagh, Z.M.1
  • 92
    • 78651480561 scopus 로고    scopus 로고
    • Cognitive decline is associated with reduced reelin expression in the entorhinal cortex of aged rats
    • Stranahan, A. M., Haberman, R. P. & Gallagher, M. Cognitive decline is associated with reduced reelin expression in the entorhinal cortex of aged rats. Cereb. Cortex 21, 392-400 (2011).
    • (2011) Cereb. Cortex , vol.21 , pp. 392-400
    • Stranahan, A.M.1    Haberman, R.P.2    Gallagher, M.3
  • 93
    • 0030805991 scopus 로고    scopus 로고
    • Frequency of stages of Alzheimer-related lesions in different age categories
    • Braak, H. & Braak, E. Frequency of stages of Alzheimer-related lesions in different age categories. Neurobiol. Aging 18, 351-357 (1997).
    • (1997) Neurobiol. Aging , vol.18 , pp. 351-357
    • Braak, H.1    Braak, E.2
  • 94
    • 84893763207 scopus 로고    scopus 로고
    • Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease
    • Khan, U. A. et al. Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease. Nat. Neurosci. 17, 304-311 (2014).
    • (2014) Nat. Neurosci , vol.17 , pp. 304-311
    • Khan, U.A.1
  • 95
    • 84901308188 scopus 로고    scopus 로고
    • Performance on a pattern separation task by Alzheimer's patients shows possible links between disrupted dentate gyrus activity and apolipoprotein e - 4 status and cerebrospinal fluid amyloid-β 42 levels
    • Wesnes, K. A., Annas, P., Basun, H., Edgar, C. & Blennow, K. Performance on a pattern separation task by Alzheimer's patients shows possible links between disrupted dentate gyrus activity and apolipoprotein E - 4 status and cerebrospinal fluid amyloid-β 42 levels. Alzheimers Res. Ther. 6, 20 (2014).
    • (2014) Alzheimers Res. Ther , vol.6 , pp. 20
    • Wesnes, K.A.1    Annas, P.2    Basun, H.3    Edgar, C.4    Blennow, K.5
  • 96
    • 85016047612 scopus 로고    scopus 로고
    • Tau and β -amyloid are associated with medial temporal lobe structure, function and memory encoding in normal aging
    • Marks, S. M., Lockhart, S. N., Baker, S. L. & Jagust, W. J. Tau and β -amyloid are associated with medial temporal lobe structure, function and memory encoding in normal aging. J. Neurosci. 37, 3192-3201 (2017).
    • (2017) J. Neurosci , vol.37 , pp. 3192-3201
    • Marks, S.M.1    Lockhart, S.N.2    Baker, S.L.3    Jagust, W.J.4
  • 97
    • 84920973406 scopus 로고    scopus 로고
    • Changes in pattern completion: A key mechanism to explain age-related recognition memory deficits?
    • Vieweg, P., Stangl, M., Howard, L. R. & Wolbers, T. Changes in pattern completion: a key mechanism to explain age-related recognition memory deficits? Cortex 64, 343-351 (2015).
    • (2015) Cortex , vol.64 , pp. 343-351
    • Vieweg, P.1    Stangl, M.2    Howard, L.R.3    Wolbers, T.4
  • 98
    • 84930412660 scopus 로고    scopus 로고
    • Stability of age-related deficits in the mnemonic similarity task across task variations
    • Stark, S. M., Stevenson, R., Wu, C., Rutledge, S. & Stark, C. E. L. Stability of age-related deficits in the mnemonic similarity task across task variations. Behav. Neurosci. 129, 257-268 (2015).
    • (2015) Behav. Neurosci , vol.129 , pp. 257-268
    • Stark, S.M.1    Stevenson, R.2    Wu, C.3    Rutledge, S.4    Stark, C.E.L.5
  • 99
    • 33846629921 scopus 로고    scopus 로고
    • A model of hippocampal neurogenesis in memory and mood disorders
    • Becker, S. & Wojtowicz, J. M. A model of hippocampal neurogenesis in memory and mood disorders. Trends Cogn. Sci. 11, 70-76 (2007).
    • (2007) Trends Cogn. Sci , vol.11 , pp. 70-76
    • Becker, S.1    Wojtowicz, J.M.2
  • 100
    • 79956221127 scopus 로고    scopus 로고
    • Pattern separation: A common function for new neurons in hippocampus and olfactory bulb
    • Sahay, A., Wilson, D. A. & Hen, R. Pattern separation: a common function for new neurons in hippocampus and olfactory bulb. Neuron 70, 582-588 (2011).
    • (2011) Neuron , vol.70 , pp. 582-588
    • Sahay, A.1    Wilson, D.A.2    Hen, R.3
  • 101
    • 84870558067 scopus 로고    scopus 로고
    • Neurogenesis and generalization: A new approach to stratify and treat anxiety disorders
    • Kheirbek, M. A., Klemenhagen, K. C., Sahay, A. & Hen, R. Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders. Nat. Neurosci. 15, 1613-1620 (2012).
    • (2012) Nat. Neurosci , vol.15 , pp. 1613-1620
    • Kheirbek, M.A.1    Klemenhagen, K.C.2    Sahay, A.3    Hen, R.4
  • 102
    • 84949625589 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis, fear generalization and stress
    • Besnard, A. & Sahay, A. Adult hippocampal neurogenesis, fear generalization and stress. Neuropsychopharmacology 41, 24-44 (2016).
    • (2016) Neuropsychopharmacology , vol.41 , pp. 24-44
    • Besnard, A.1    Sahay, A.2
  • 103
    • 34248389660 scopus 로고    scopus 로고
    • Low episodic memory performance as a premorbid marker of depression: Evidence from a 3-year follow-up
    • Airaksinen, E., Wahlin, A., Forsell, Y. & Larsson, M. Low episodic memory performance as a premorbid marker of depression: evidence from a 3-year follow-up. Acta Psychiatr. Scand. 115, 458-465 (2007).
    • (2007) Acta Psychiatr. Scand , vol.115 , pp. 458-465
    • Airaksinen, E.1    Wahlin, A.2    Forsell, Y.3    Larsson, M.4
  • 104
    • 77956426174 scopus 로고    scopus 로고
    • Emotion and episodic memory in neuropsychiatric disorders
    • Dere, E., Pause, B. M. & Pietrowsky, R. Emotion and episodic memory in neuropsychiatric disorders. Behav. Brain Res. 215, 162-171 (2010).
    • (2010) Behav. Brain Res , vol.215 , pp. 162-171
    • Dere, E.1    Pause, B.M.2    Pietrowsky, R.3
  • 105
    • 7444239843 scopus 로고    scopus 로고
    • Cellular changes in the postmortem hippocampus in major depression
    • Stockmeier, C. A. et al. Cellular changes in the postmortem hippocampus in major depression. Biol. Psychiatry 56, 640-650 (2004).
    • (2004) Biol. Psychiatry , vol.56 , pp. 640-650
    • Stockmeier, C.A.1
  • 107
    • 0026781307 scopus 로고
    • Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons
    • Watanabe, Y., Gould, E. & McEwen, B. S. Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons. Brain Res. 588, 341-345 (1992).
    • (1992) Brain Res , vol.588 , pp. 341-345
    • Watanabe, Y.1    Gould, E.2    McEwen, B.S.3
  • 108
    • 33745625840 scopus 로고    scopus 로고
    • What is the functional significance of chronic stress-induced CA3 dendritic retraction within the hippocampus?
    • Conrad, C. D. What is the functional significance of chronic stress-induced CA3 dendritic retraction within the hippocampus? Behav. Cogn. Neurosci. Rev 5, 41-60 (2006).
    • (2006) Behav. Cogn. Neurosci. Rev , vol.5 , pp. 41-60
    • Conrad, C.D.1
  • 109
    • 34548348778 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis in depression
    • Sahay, A. & Hen, R. Adult hippocampal neurogenesis in depression. Nat. Neurosci. 10, 1110-1115 (2007).
    • (2007) Nat. Neurosci , vol.10 , pp. 1110-1115
    • Sahay, A.1    Hen, R.2
  • 110
    • 84882807311 scopus 로고    scopus 로고
    • A possible negative influence of depression on the ability to overcome memory interference
    • Shelton, D. J. & Kirwan, C. B. A possible negative influence of depression on the ability to overcome memory interference. Behav. Brain Res. 256, 20-26 (2013).
    • (2013) Behav. Brain Res , vol.256 , pp. 20-26
    • Shelton, D.J.1    Kirwan, C.B.2
  • 111
    • 84878822765 scopus 로고    scopus 로고
    • Adult hippocampal neurogenesis reduces memory interference in humans: Opposing effects of aerobic exercise and depression
    • Déry, N. et al. Adult hippocampal neurogenesis reduces memory interference in humans: opposing effects of aerobic exercise and depression. Front. Neurosci. 7, 66 (2013).
    • (2013) Front. Neurosci , vol.7 , pp. 66
    • Déry, N.1
  • 113
    • 84892679015 scopus 로고    scopus 로고
    • Depressive mood modulates the anterior lateral CA1 and DG/CA3 during a pattern separation task in cognitively intact individuals: A functional MRI study
    • Fujii, T., Saito, D. N., Yanaka, H. T., Kosaka, H. & Okazawa, H. Depressive mood modulates the anterior lateral CA1 and DG/CA3 during a pattern separation task in cognitively intact individuals: a functional MRI study. Hippocampus 24, 214-224 (2014).
    • (2014) Hippocampus , vol.24 , pp. 214-224
    • Fujii, T.1    Saito, D.N.2    Yanaka, H.T.3    Kosaka, H.4    Okazawa, H.5
  • 114
    • 85012049360 scopus 로고    scopus 로고
    • Disruption of amygdala-entorhinal-hippocampal network in late-life depression
    • Leal, S. L., Noche, J. A., Murray, E. A. & Yassa, M. A. Disruption of amygdala-entorhinal-hippocampal network in late-life depression. Hippocampus 27, 464-476 (2017).
    • (2017) Hippocampus , vol.27 , pp. 464-476
    • Leal, S.L.1    Noche, J.A.2    Murray, E.A.3    Yassa, M.A.4
  • 115
    • 84945232042 scopus 로고    scopus 로고
    • Effect of anxiety on behavioural pattern separation in humans
    • Balderston, N. L. et al. Effect of anxiety on behavioural pattern separation in humans. Cogn. Emot. 31, 238-248 (2017).
    • (2017) Cogn. Emot , vol.31 , pp. 238-248
    • Balderston, N.L.1
  • 116
    • 1842858241 scopus 로고    scopus 로고
    • Schizophrenia
    • (eds. Baddeley, A. D., Kopelman, M. D. & Wilson, B. A.), (John Wiley & Sons, Chichester, UK
    • McKenna, P., Ornstein, T. & Baddeley, A. D. Schizophrenia. in The Handbook of Memory Disorders (eds. Baddeley, A. D., Kopelman, M. D. & Wilson, B. A.) 413-435 (John Wiley & Sons, Chichester, UK, 2003).
    • (2003) The Handbook of Memory Disorders , pp. 413-435
    • McKenna, P.1    Ornstein, T.2    Baddeley, A.D.3
  • 117
    • 77957952253 scopus 로고    scopus 로고
    • The hippocampal formation in schizophrenia
    • Tamminga, C. A., Stan, A. D. & Wagner, A. D. The hippocampal formation in schizophrenia. Am. J. Psychiatry 167, 1178-1193 (2010).
    • (2010) Am. J. Psychiatry , vol.167 , pp. 1178-1193
    • Tamminga, C.A.1    Stan, A.D.2    Wagner, A.D.3
  • 118
    • 0033914752 scopus 로고    scopus 로고
    • Ionotropic glutamate receptors and expression of N-methyld- aspartate receptor subunits in subregions of human hippocampus: Effects of schizophrenia
    • Gao, X.-M. et al. Ionotropic glutamate receptors and expression of N-methyld- aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia. Am. J. Psychiatry 157, 1141-1149 (2000).
    • (2000) Am. J. Psychiatry , vol.157 , pp. 1141-1149
    • Gao, X.-M.1
  • 119
    • 84964303784 scopus 로고    scopus 로고
    • Synaptic proteins in the hippocampus indicative of increased neuronal activity in CA3 in schizophrenia
    • Li, W. et al. Synaptic proteins in the hippocampus indicative of increased neuronal activity in CA3 in schizophrenia. Am. J. Psychiatry 172, 373-382 (2015).
    • (2015) Am. J. Psychiatry , vol.172 , pp. 373-382
    • Li, W.1
  • 120
    • 69949176721 scopus 로고    scopus 로고
    • Differential targeting of the CA1 subfield of the hippocampal formation by schizophrenia and related psychotic disorders
    • Schobel, S. A. et al. Differential targeting of the CA1 subfield of the hippocampal formation by schizophrenia and related psychotic disorders. Arch. Gen. Psychiatry 66, 938-946 (2009).
    • (2009) Arch. Gen. Psychiatry , vol.66 , pp. 938-946
    • Schobel, S.A.1
  • 121
    • 84908012449 scopus 로고    scopus 로고
    • Loss of pattern separation performance in schizophrenia suggests dentate gyrus dysfunction
    • Das, T., Ivleva, E. I., Wagner, A. D., Stark, C. E. L. & Tamminga, C. A. Loss of pattern separation performance in schizophrenia suggests dentate gyrus dysfunction. Schizophr. Res. 159, 193-197 (2014).
    • (2014) Schizophr. Res , vol.159 , pp. 193-197
    • Das, T.1    Ivleva, E.I.2    Wagner, A.D.3    Stark, C.E.L.4    Tamminga, C.A.5
  • 122
    • 85017409472 scopus 로고    scopus 로고
    • Mnemonic discrimination deficits in first episode psychosis and a ketamine model suggests dentate gyrus pathology linked to NMDA-receptor hypofunction
    • Kraguljac, N. V. et al. Mnemonic discrimination deficits in first episode psychosis and a ketamine model suggests dentate gyrus pathology linked to NMDA-receptor hypofunction. Biol. Psychiatry Cogn. Neurosci. Neuroimaging https://doi.org/10.1016/j.bpsc.2017.02.005 (2017).
    • (2017) Biol. Psychiatry Cogn. Neurosci. Neuroimaging
    • Kraguljac, N.V.1
  • 123
    • 84946480051 scopus 로고    scopus 로고
    • Clarifying the role of pattern separation in schizophrenia: The role of recognition and visual discrimination deficits
    • Martinelli, C. & Shergill, S. S. Clarifying the role of pattern separation in schizophrenia: the role of recognition and visual discrimination deficits. Schizophr. Res. 166, 328-333 (2015).
    • (2015) Schizophr. Res , vol.166 , pp. 328-333
    • Martinelli, C.1    Shergill, S.S.2
  • 124
    • 84928427318 scopus 로고    scopus 로고
    • Social-cognitive, physiological, and neural mechanisms underlying emotion regulation impairments: Understanding anxiety in autism spectrum disorder
    • White, S. W. et al. Social-cognitive, physiological, and neural mechanisms underlying emotion regulation impairments: understanding anxiety in autism spectrum disorder. Int. J. Dev. Neurosci. 39, 22-36 (2014).
    • (2014) Int. J. Dev. Neurosci , vol.39 , pp. 22-36
    • White, S.W.1
  • 125
    • 84944511688 scopus 로고    scopus 로고
    • Overactive pattern separation memory associated with negative emotionality in adults diagnosed with autism spectrum disorder
    • South, M. et al. Overactive pattern separation memory associated with negative emotionality in adults diagnosed with autism spectrum disorder. J. Autism Dev. Disord. 45, 3458-3467 (2015).
    • (2015) J. Autism Dev. Disord , vol.45 , pp. 3458-3467
    • South, M.1
  • 126
    • 84963970915 scopus 로고    scopus 로고
    • Running improves pattern separation during novel object recognition
    • Bolz, L., Heigele, S. & Bischofberger, J. Running improves pattern separation during novel object recognition. Brain Plast. 1, 129-141 (2015).
    • (2015) Brain Plast , vol.1 , pp. 129-141
    • Bolz, L.1    Heigele, S.2    Bischofberger, J.3
  • 127
    • 84941049215 scopus 로고    scopus 로고
    • Running rescues a fear-based contextual discrimination deficit in aged mice
    • Wu, M. V., Luna, V. M. & Hen, R. Running rescues a fear-based contextual discrimination deficit in aged mice. Front. Syst. Neurosci. 9, 114 (2015).
    • (2015) Front. Syst. Neurosci , vol.9 , pp. 114
    • Wu, M.V.1    Luna, V.M.2    Hen, R.3
  • 128
    • 85011407758 scopus 로고    scopus 로고
    • Acute moderate exercise improves mnemonic discrimination in young adults
    • Suwabe, K. et al. Acute moderate exercise improves mnemonic discrimination in young adults. Hippocampus 27, 229-234 (2017).
    • (2017) Hippocampus , vol.27 , pp. 229-234
    • Suwabe, K.1
  • 129
    • 84929134723 scopus 로고    scopus 로고
    • Vascular hippocampal plasticity after aerobic exercise in older adults
    • Maass, A. et al. Vascular hippocampal plasticity after aerobic exercise in older adults. Mol. Psychiatry 20, 585-593 (2015).
    • (2015) Mol. Psychiatry , vol.20 , pp. 585-593
    • Maass, A.1
  • 130
    • 85023164709 scopus 로고    scopus 로고
    • Aerobic fitness associates with mnemonic discrimination as a mediator of physical activity effects: Evidence for memory flexibility in young adults
    • Suwabe, K. et al. Aerobic fitness associates with mnemonic discrimination as a mediator of physical activity effects: evidence for memory flexibility in young adults. Sci. Rep. 7, 5140 (2017).
    • (2017) Sci. Rep , vol.7 , pp. 5140
    • Suwabe, K.1
  • 131
  • 132
    • 80053569697 scopus 로고    scopus 로고
    • Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable?
    • Bekinschtein, P., Oomen, C. A., Saksida, L. M. & Bussey, T. J. Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable? Semin. Cell Dev. Biol. 22, 536-542 (2011).
    • (2011) Semin. Cell Dev. Biol , vol.22 , pp. 536-542
    • Bekinschtein, P.1    Oomen, C.A.2    Saksida, L.M.3    Bussey, T.J.4
  • 133
    • 84949595730 scopus 로고    scopus 로고
    • Virtual environmental enrichment through video games improves hippocampal-associated memory
    • Clemenson, G. D. & Stark, C. E. L. Virtual environmental enrichment through video games improves hippocampal-associated memory. J. Neurosci. 35, 16116-16125 (2015).
    • (2015) J. Neurosci , vol.35 , pp. 16116-16125
    • Clemenson, G.D.1    Stark, C.E.L.2
  • 134
    • 84893807162 scopus 로고    scopus 로고
    • Post-study caffeine administration enhances memory consolidation in humans
    • Borota, D. et al. Post-study caffeine administration enhances memory consolidation in humans. Nat. Neurosci. 17, 201-203 (2014).
    • (2014) Nat. Neurosci , vol.17 , pp. 201-203
    • Borota, D.1
  • 135
    • 84924767480 scopus 로고    scopus 로고
    • Response of the medial temporal lobe network in amnestic mild cognitive impairment to therapeutic intervention assessed by fMRI and memory task performance
    • Bakker, A., Albert, M. S., Krauss, G., Speck, C. L. & Gallagher, M. Response of the medial temporal lobe network in amnestic mild cognitive impairment to therapeutic intervention assessed by fMRI and memory task performance. Neuroimage Clin. 7, 688-698 (2015).
    • (2015) Neuroimage Clin , vol.7 , pp. 688-698
    • Bakker, A.1    Albert, M.S.2    Krauss, G.3    Speck, C.L.4    Gallagher, M.5
  • 136
    • 76749092618 scopus 로고    scopus 로고
    • Treatment strategies targeting excess hippocampal activity benefit aged rats with cognitive impairment
    • Koh, M. T., Haberman, R. P., Foti, S., McCown, T. J. & Gallagher, M. Treatment strategies targeting excess hippocampal activity benefit aged rats with cognitive impairment. Neuropsychopharmacology 35, 1016-1025 (2010).
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1016-1025
    • Koh, M.T.1    Haberman, R.P.2    Foti, S.3    McCown, T.J.4    Gallagher, M.5
  • 137
    • 84958130075 scopus 로고    scopus 로고
    • The antiepileptic drug levetiracetam improves auditory gating in DBA/2 mice
    • Smucny, J., Stevens, K. E. & Tregellas, J. R. The antiepileptic drug levetiracetam improves auditory gating in DBA/2 mice. NPJ Schizophr. 1, 15002 (2015).
    • (2015) NPJ Schizophr , vol.1 , pp. 15002
    • Smucny, J.1    Stevens, K.E.2    Tregellas, J.R.3
  • 138
    • 84867645474 scopus 로고    scopus 로고
    • Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model
    • Sanchez, P. E. et al. Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model. Proc. Natl. Acad. Sci. USA 109, E2895-E2903 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. E2895-E2903
    • Sanchez, P.E.1
  • 139
    • 84928173252 scopus 로고    scopus 로고
    • Hippocampal subfields and major depressive disorder
    • Adam Samuels, B., Leonardo, E. D. & Hen, R. Hippocampal subfields and major depressive disorder. Biol. Psychiatry 77, 210-211 (2015).
    • (2015) Biol. Psychiatry , vol.77 , pp. 210-211
    • Adam Samuels, B.1    Leonardo, E.D.2    Hen, R.3
  • 140
    • 84925718653 scopus 로고    scopus 로고
    • Illness progression, recent stress, and morphometry of hippocampal subfields and medial prefrontal cortex in major depression
    • Treadway, M. T. et al. Illness progression, recent stress, and morphometry of hippocampal subfields and medial prefrontal cortex in major depression. Biol. Psychiatry 77, 285-294 (2015).
    • (2015) Biol. Psychiatry , vol.77 , pp. 285-294
    • Treadway, M.T.1
  • 141
    • 84877153207 scopus 로고    scopus 로고
    • Neuronal plasticity and antidepressant actions
    • Castrén, E. & Hen, R. Neuronal plasticity and antidepressant actions. Trends Neurosci. 36, 259-267 (2013).
    • (2013) Trends Neurosci , vol.36 , pp. 259-267
    • Castrén, E.1    Hen, R.2
  • 142
    • 84871798259 scopus 로고    scopus 로고
    • Suppression of adult neurogenesis impairs population coding of similar contexts in hippocampal CA3 region
    • Niibori, Y. et al. Suppression of adult neurogenesis impairs population coding of similar contexts in hippocampal CA3 region. Nat. Commun. 3, 1253 (2012).
    • (2012) Nat. Commun , vol.3 , pp. 1253
    • Niibori, Y.1
  • 143
    • 84878831768 scopus 로고    scopus 로고
    • Dynamics of hippocampal neurogenesis in adult humans
    • Spalding, K. L. et al. Dynamics of hippocampal neurogenesis in adult humans. Cell 153, 1219-1227 (2013).
    • (2013) Cell , vol.153 , pp. 1219-1227
    • Spalding, K.L.1
  • 144
    • 36048970985 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain
    • Manganas, L. N. et al. Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain. Science 318, 980-985 (2007).
    • (2007) Science , vol.318 , pp. 980-985
    • Manganas, L.N.1
  • 145
  • 146
    • 84888132593 scopus 로고    scopus 로고
    • Pattern separation and pattern completion in Alzheimer's disease: Evidence of rapid forgetting in amnestic mild cognitive impairment
    • Ally, B. A., Hussey, E. P., Ko, P. C. & Molitor, R. J. Pattern separation and pattern completion in Alzheimer's disease: evidence of rapid forgetting in amnestic mild cognitive impairment. Hippocampus 23, 1246-1258 (2013).
    • (2013) Hippocampus , vol.23 , pp. 1246-1258
    • Ally, B.A.1    Hussey, E.P.2    Ko, P.C.3    Molitor, R.J.4


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