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Volumn 9, Issue AUGUST, 2015, Pages

Running rescues a fear-based contextual discrimination deficit in aged mice

Author keywords

Aging; Dentate gyrus; Exercise; Neurogenesis; Pattern separation

Indexed keywords

ADULT; AGE; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR; COGNITION; CONTROLLED STUDY; DENDRITE; DENTATE GYRUS; DISCRIMINATIVE STIMULUS; EXERCISE; FEAR; HIPPOCAMPUS; MALE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NOVELTY SUPPRESSED FEEDING TEST; OPEN FIELD TEST; PERCEPTIVE DISCRIMINATION; RUNNING; SYNAPTIC TRANSMISSION;

EID: 84941049215     PISSN: 16625137     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnsys.2015.00114     Document Type: Article
Times cited : (32)

References (45)
  • 1
    • 79956192109 scopus 로고    scopus 로고
    • Resolving newmemories:Acritical look at the dentate gyrus, adult neurogenesis, and pattern separation
    • Aimone, J. B., Deng, W., and Gage, F. H. (2011). Resolving newmemories:acritical look at the dentate gyrus, adult neurogenesis, and pattern separation. Neuron 70, 589-596. doi:10.1016/j.neuron.2011.05.010.
    • (2011) Neuron , vol.70 , pp. 589-596
    • Aimone, J.B.1    Deng, W.2    Gage, F.H.3
  • 2
    • 32044464079 scopus 로고    scopus 로고
    • Mild forced treadmill exercise enhances spatial learning in the aged rat
    • Albeck, D. S., Sano, K., Prewitt, G. E., and Dalton, L. (2006). Mild forced treadmill exercise enhances spatial learning in the aged rat. Behav. Brain Res. 168, 345-348. doi:10.1016/j.bbr.2005.11.008.
    • (2006) Behav. Brain Res , vol.168 , pp. 345-348
    • Albeck, D.S.1    Sano, K.2    Prewitt, G.E.3    Dalton, L.4
  • 3
    • 70349462983 scopus 로고    scopus 로고
    • Prolonged voluntary wheel-running stimulates neural precursors in the hippocampus and forebrain of adult CD1 mice
    • Bednarczyk, M. R., Aumont, A., Décary, S., Bergeron, R., and Fernandes, K. J. (2009). Prolonged voluntary wheel-running stimulates neural precursors in the hippocampus and forebrain of adult CD1 mice. Hippocampus 19, 913-927. doi:10.1002/hipo.20621.
    • (2009) Hippocampus , vol.19 , pp. 913-927
    • Bednarczyk, M.R.1    Aumont, A.2    Décary, S.3    Bergeron, R.4    Fernandes, K.J.5
  • 4
    • 1242271233 scopus 로고    scopus 로고
    • Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice
    • Bondolfi, L., Ermini, F., Long, J. M., Ingram, D. K., and Jucker, M. (2004). Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice. Neurobiol. Aging 25, 333-340. doi:10.1016/S0197-4580(03)00083-6.
    • (2004) Neurobiol. Aging , vol.25 , pp. 333-340
    • Bondolfi, L.1    Ermini, F.2    Long, J.M.3    Ingram, D.K.4    Jucker, M.5
  • 5
    • 84928885704 scopus 로고    scopus 로고
    • Involvement of hippocampal inputs and intrinsic circuit in the acquisition of context and cues during classical conditioning in behaving rabbits
    • Carretero-Guillen, A., Pacheco-Calderon, R., Delgado-Garcia, J. M., and Gruart, A. (2015). Involvement of hippocampal inputs and intrinsic circuit in the acquisition of context and cues during classical conditioning in behaving rabbits. Cereb. Cortex 25, 1278-1289. doi:10.1093/cercor/bht321.
    • (2015) Cereb. Cortex , vol.25 , pp. 1278-1289
    • Carretero-Guillen, A.1    Pacheco-Calderon, R.2    Delgado-Garcia, J.M.3    Gruart, A.4
  • 6
    • 67650450542 scopus 로고    scopus 로고
    • A functional role for adult hippocampal neurogenesis in spatial pattern separation
    • Clelland, C. D., Choi, M., Romberg, C., Clemenson, G. D. Jr., Fragniere, A., Tyers, P., et al. (2009). A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science 325, 210-213. doi:10.1126/science.1173215.
    • (2009) Science , vol.325 , pp. 210-213
    • Clelland, C.D.1    Choi, M.2    Romberg, C.3    Clemenson, G.D.4    Fragniere, A.5    Tyers, P.6
  • 7
    • 84922633219 scopus 로고    scopus 로고
    • Enrichment rescues contextual discrimination deficit associated with immediate shock
    • Clemenson, G. D., Lee, S. W., Deng, W., Barrera, V. R., Iwamoto, K. S., Fanselow, M. S., et al. (2015). Enrichment rescues contextual discrimination deficit associated with immediate shock. Hippocampus 25, 385-392. doi:10.1002/hipo.22380.
    • (2015) Hippocampus , vol.25 , pp. 385-392
    • Clemenson, G.D.1    Lee, S.W.2    Deng, W.3    Barrera, V.R.4    Iwamoto, K.S.5    Fanselow, M.S.6
  • 8
    • 0038050784 scopus 로고    scopus 로고
    • Fitness effects on the cognitive function of older adults:Ameta-analytic study
    • Colcombe, S., and Kramer, A. F. (2003). Fitness effects on the cognitive function of older adults:ameta-analytic study. Psychol. Sci. 14,125-130. doi:10.1111/1467-9280.t01-1-01430.
    • (2003) Psychol. Sci , vol.14 , pp. 125-130
    • Colcombe, S.1    Kramer, A.F.2
  • 12
    • 84879888831 scopus 로고    scopus 로고
    • Age-related changes in place learning for adjacent and separate locations
    • Gracian, E. I., Shelley, L. E., Morris, A. M., and Gilbert, P. E. (2013). Age-related changes in place learning for adjacent and separate locations. Neurobiol. Aging 34, 2304-2309. doi:10.1016/j.neurobiolaging.2013.03.033.
    • (2013) Neurobiol. Aging , vol.34 , pp. 2304-2309
    • Gracian, E.I.1    Shelley, L.E.2    Morris, A.M.3    Gilbert, P.E.4
  • 13
    • 43649097836 scopus 로고    scopus 로고
    • Aged wild-type and APP, PS1, and APP+PS1 mice present similar deficits in associative learning and synaptic plasticity independent of amyloid load
    • Gruart, A., López-Ramos, J. C., Munoz, M. D., and Delgado-García, J. M. (2008). Aged wild-type and APP, PS1, and APP+PS1 mice present similar deficits in associative learning and synaptic plasticity independent of amyloid load. Neurobiol. Dis. 30, 439-450. doi:10.1016/j.nbd.2008.03.001.
    • (2008) Neurobiol. Dis , vol.30 , pp. 439-450
    • Gruart, A.1    López-Ramos, J.C.2    Munoz, M.D.3    Delgado-García, J.M.4
  • 14
    • 31544478260 scopus 로고    scopus 로고
    • Impairment of water maze behaviour with ageing is counteracted by maze learning earlier in life but not by physical exercise, food restriction or housing conditions
    • Hansalik, M., Skalicky, M., and Viidik, A. (2006). Impairment of water maze behaviour with ageing is counteracted by maze learning earlier in life but not by physical exercise, food restriction or housing conditions. Exp. Gerontol. 41, 169-174. doi:10.1016/j.exger.2005.11.002.
    • (2006) Exp. Gerontol , vol.41 , pp. 169-174
    • Hansalik, M.1    Skalicky, M.2    Viidik, A.3
  • 15
    • 84904903561 scopus 로고    scopus 로고
    • A comparison of neural responses to appetitive and aversive stimuli in humans and other mammals
    • Hayes, D. J., Duncan, N. W., Xu, J., and Northoff, G. (2014). A comparison of neural responses to appetitive and aversive stimuli in humans and other mammals. Neurosci. Biobehav. Rev. 45C, 350-368. doi:10.1016/j.neubiorev.2014.06.018.
    • (2014) Neurosci. Biobehav. Rev , vol.45C , pp. 350-368
    • Hayes, D.J.1    Duncan, N.W.2    Xu, J.3    Northoff, G.4
  • 16
    • 37349069492 scopus 로고    scopus 로고
    • Be smart, exercise your heart:Exercise effects on brain and cognition
    • Hillman, C. H., Erickson, K. I., and Kramer, A. F. (2008). Be smart, exercise your heart:exercise effects on brain and cognition. Nat. Rev. Neurosci. 9, 58-65. doi:10.1038/nrn2298.
    • (2008) Nat. Rev. Neurosci , vol.9 , pp. 58-65
    • Hillman, C.H.1    Erickson, K.I.2    Kramer, A.F.3
  • 17
    • 84879781233 scopus 로고    scopus 로고
    • Exercise counteracts declining hippocampal function in aging and Alzheimer’s disease
    • Intlekofer, K. A., and Cotman, C. W. (2013). Exercise counteracts declining hippocampal function in aging and Alzheimer’s disease. Neurobiol. Dis. 57, 47-55. doi:10.1016/j.nbd.2012.06.011.
    • (2013) Neurobiol. Dis , vol.57 , pp. 47-55
    • Intlekofer, K.A.1    Cotman, C.W.2
  • 18
    • 84914680502 scopus 로고    scopus 로고
    • The lonely mouse - single housing affects serotonergic signaling integrity measured by 8-OH-DPAT-induced hypothermia in male mice
    • Kalliokoski, O., Teilmann, A. C., Jacobsen, K. R., Abelson, K. S., and Hau, J. (2014). The lonely mouse - single housing affects serotonergic signaling integrity measured by 8-OH-DPAT-induced hypothermia in male mice. PLoS ONE 9:e111065. doi:10.1371/journal.pone.0111065.
    • (2014) Plos ONE , vol.9
    • Kalliokoski, O.1    Teilmann, A.C.2    Jacobsen, K.R.3    Abelson, K.S.4    Hau, J.5
  • 19
    • 84870558067 scopus 로고    scopus 로고
    • Neurogenesis and generalization:A new approach to stratify and treat anxiety disorders
    • Kheirbek, M. A., Klemenhagen, K. C., Sahay, A., and Hen, R. (2012). Neurogenesis and generalization:a new approach to stratify and treat anxiety disorders. Nat. Neurosci. 15, 1613-1620. doi:10.1038/nn.3262.
    • (2012) Nat. Neurosci , vol.15 , pp. 1613-1620
    • Kheirbek, M.A.1    Klemenhagen, K.C.2    Sahay, A.3    Hen, R.4
  • 20
    • 79961193015 scopus 로고    scopus 로고
    • Voluntary wheel running reverses age- induced changes in hippocampal gene expression
    • Kohman, R. A., Rodriguez-Zas, S. L., Southey, B. R., Kelley, K. W., Dantzer, R., and Rhodes, J. S. (2011). Voluntary wheel running reverses age- induced changes in hippocampal gene expression. PLoS ONE 6:e22654. doi:10.1371/journal.pone.0022654.
    • (2011) Plos ONE , vol.6
    • Kohman, R.A.1    Rodriguez-Zas, S.L.2    Southey, B.R.3    Kelley, K.W.4    Dantzer, R.5    Rhodes, J.S.6
  • 21
    • 33748188974 scopus 로고    scopus 로고
    • Physical exercise prevents age-related decline in precursor cell activity in the mouse dentate gyrus
    • Kronenberg, G., Bick-Sander, A., Bunk, E., Wolf, C., Ehninger, D., and Kempermann, G. (2006). Physical exercise prevents age-related decline in precursor cell activity in the mouse dentate gyrus. Neurobiol. Aging 27, 1505-1513. doi:10.1016/j.neurobiolaging.2005.09.016.
    • (2006) Neurobiol. Aging , vol.27 , pp. 1505-1513
    • Kronenberg, G.1    Bick-Sander, A.2    Bunk, E.3    Wolf, C.4    Ehninger, D.5    Kempermann, G.6
  • 22
    • 0029863342 scopus 로고    scopus 로고
    • Neurogenesis in the dentate gyrus of the adult rat:Age-related decrease of neuronal progenitor proliferation
    • Kuhn, H. G., Dickinson-Anson, H., and Gage, F. H. (1996). Neurogenesis in the dentate gyrus of the adult rat:age-related decrease of neuronal progenitor proliferation. J. Neurosci. 16, 2027-2033.
    • (1996) J. Neurosci , vol.16 , pp. 2027-2203
    • Kuhn, H.G.1    Dickinson-Anson, H.2    Gage, F.H.3
  • 23
    • 33644800309 scopus 로고    scopus 로고
    • Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older
    • Larson, E. B., Wang, L., Bowen, J. D., McCormick, W. C., Teri, L., Crane, P., et al. (2006). Exercise is associated with reduced risk for incident dementia among persons 65 years of age and older. Ann. Intern. Med. 144, 73-81. doi:10.7326/0003-4819-144-2-200601170-00004.
    • (2006) Ann. Intern. Med , vol.144 , pp. 73-81
    • Larson, E.B.1    Wang, L.2    Bowen, J.D.3    McCormick, W.C.4    Teri, L.5    Crane, P.6
  • 24
    • 50949110086 scopus 로고    scopus 로고
    • Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease:A randomized trial
    • Lautenschlager, N. T., Cox, K. L., Flicker, L., Foster, J. K., van Bockxmeer, F. M., Xiao, J., et al. (2008). Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease:a randomized trial. JAMA 300, 1027-1037. doi:10.1001/jama.300.9.1027.
    • (2008) JAMA , vol.300 , pp. 1027-1037
    • Lautenschlager, N.T.1    Cox, K.L.2    Flicker, L.3    Foster, J.K.4    Van Bockxmeer, F.M.5    Xiao, J.6
  • 25
    • 77956194308 scopus 로고    scopus 로고
    • Effects of enriched physical and social environment on motor performance, associative learning, and hippocampal neurogenesis in mice
    • Madroñal, N., Lopez-Aracil, C., Rangel, A., del Rio, J. A., Delgado-Garcia, J. M., and Gruart, A. (2010). Effects of enriched physical and social environment on motor performance, associative learning, and hippocampal neurogenesis in mice. PLoS ONE 5:e11130. doi:10.1371/journal.pone.0011130.
    • (2010) Plos ONE , vol.5
    • Madroñal, N.1    Lopez-Aracil, C.2    Rangel, A.3    Del Rio, J.A.4    Delgado-Garcia, J.M.5    Gruart, A.6
  • 26
    • 33745684603 scopus 로고    scopus 로고
    • Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment
    • Meshi, D., Drew, M. R., Saxe, M., Ansorge, M. S., David, D., Santarelli, L., et al. (2006). Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment. Nat. Neurosci. 9, 729-731. doi:10.1038/nn1696.
    • (2006) Nat. Neurosci , vol.9 , pp. 729-731
    • Meshi, D.1    Drew, M.R.2    Saxe, M.3    Ansorge, M.S.4    David, D.5    Santarelli, L.6
  • 27
    • 84864712752 scopus 로고    scopus 로고
    • The effect of emotional arousal and retention delay on subsequent-memory effects
    • Mickley Steinmetz, K. R., Schmidt, K., Zucker, H. R., and Kensinger, E. A. (2012). The effect of emotional arousal and retention delay on subsequent-memory effects. Cogn. Neurosci. 3, 150-159. doi:10.1080/17588928.2012.677421.
    • (2012) Cogn. Neurosci , vol.3 , pp. 150-159
    • Mickley Steinmetz, K.R.1    Schmidt, K.2    Zucker, H.R.3    Kensinger, E.A.4
  • 28
    • 70349451730 scopus 로고    scopus 로고
    • Long-term treadmill exposure protects against age-related neurodegenerative change in the rat hippocampus
    • O’Callaghan, R. M., Griffin, E. W., and Kelly, A. M. (2009). Long-term treadmill exposure protects against age-related neurodegenerative change in the rat hippocampus. Hippocampus 19, 1019-1029. doi:10.1002/hipo.20591.
    • (2009) Hippocampus , vol.19 , pp. 1019-1029
    • O’Callaghan, R.M.1    Griffin, E.W.2    Kelly, A.M.3
  • 30
    • 0037936789 scopus 로고    scopus 로고
    • Impact of aging on hippocampal function:Plasticity, network dynamics, and cognition
    • Rosenzweig, E. S., and Barnes, C. A. (2003). Impact of aging on hippocampal function:plasticity, network dynamics, and cognition. Prog. Neurobiol. 69, 143-179. doi:10.1016/S0301-0082(02)00126-0.
    • (2003) Prog. Neurobiol , vol.69 , pp. 143-179
    • Rosenzweig, E.S.1    Barnes, C.A.2
  • 31
    • 79955526702 scopus 로고    scopus 로고
    • Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation
    • Sahay, A., Scobie, K. N., Hill, A. S., O’Carroll, C. M., Kheirbek, M. A., Burghardt, N. S., et al. (2011a). Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation. Nature 472, 466-470. doi:10.1038/nature09817.
    • (2011) Nature , vol.472 , pp. 466-470
    • Sahay, A.1    Scobie, K.N.2    Hill, A.S.3    O’Carroll, C.M.4    Kheirbek, M.A.5    Burghardt, N.S.6
  • 32
    • 79956221127 scopus 로고    scopus 로고
    • Pattern separation:A common function for new neurons in hippocampus and olfactory bulb
    • Sahay, A., Wilson, D. A., and Hen, R. (2011b). Pattern separation:a common function for new neurons in hippocampus and olfactory bulb. Neuron 70, 582-588. doi:10.1016/j.neuron.2011.05.012.
    • (2011) Neuron , vol.70 , pp. 582-588
    • Sahay, A.1    Wilson, D.A.2    Hen, R.3
  • 33
    • 2342557824 scopus 로고    scopus 로고
    • Imaging correlates of brain function in monkeys and rats isolates a hippocampal subregion differentially vulnerable to aging
    • Small, S. A., Chawla, M. K., Buonocore, M., Rapp, P. R., and Barnes, C. A. (2004). Imaging correlates of brain function in monkeys and rats isolates a hippocampal subregion differentially vulnerable to aging. Proc. Natl. Acad. Sci. U.S.A. 101, 7181-7186. doi:10.1073/pnas.04002.85101.
    • (2004) Proc. Natl. Acad. Sci , vol.101 , pp. 7181-7186
    • Small, S.A.1    Chawla, M.K.2    Buonocore, M.3    Rapp, P.R.4    Barnes, C.A.5
  • 34
    • 77953054528 scopus 로고    scopus 로고
    • Individual differences in spatial pattern separation performance associated with healthy aging in humans
    • Stark, S. M., Yassa, M. A., and Stark, C. E. (2010). Individual differences in spatial pattern separation performance associated with healthy aging in humans. Learn. Mem. 17,284-288. doi:10.1101/lm.1768110.
    • (2010) Learn. Mem , vol.17 , pp. 284-288
    • Stark, S.M.1    Yassa, M.A.2    Stark, C.E.3
  • 35
    • 84884165962 scopus 로고    scopus 로고
    • Neurogenesis along the septo-temporal axis of the hippocampus:Are depression and the action of antidepressants region-specific?
    • Tanti, A., and Belzung, C. (2013). Neurogenesis along the septo-temporal axis of the hippocampus:are depression and the action of antidepressants region-specific? Neuroscience 252, 234-252. doi:10.1016/j.neuroscience.2013.08.017.
    • (2013) Neuroscience , vol.252 , pp. 234-252
    • Tanti, A.1    Belzung, C.2
  • 36
    • 33845209203 scopus 로고    scopus 로고
    • BrdU immunohistochemistry for studying adult neurogenesis:Paradigms, pitfalls, limitations, and validation
    • Taupin, P. (2007). BrdU immunohistochemistry for studying adult neurogenesis:paradigms, pitfalls, limitations, and validation. Brain Res. Rev. 53, 198-214. doi:10.1016/j.brainresrev.2006.08.002.
    • (2007) Brain Res. Rev , vol.53 , pp. 198-214
    • Taupin, P.1
  • 37
    • 66149091970 scopus 로고    scopus 로고
    • Visual object pattern separation deficits in nondemented older adults
    • Toner, C. K., Pirogovsky, E., Kirwan, C. B., and Gilbert, P. E. (2009). Visual object pattern separation deficits in nondemented older adults. Learn. Mem. 16, 338-342. doi:10.1101/lm.1315109.
    • (2009) Learn. Mem , vol.16 , pp. 338-342
    • Toner, C.K.1    Pirogovsky, E.2    Kirwan, C.B.3    Gilbert, P.E.4
  • 38
    • 84856090354 scopus 로고    scopus 로고
    • Adult-born neurons are necessary for extended contextual discrimination
    • Tronel, S., Belnoue, L., Grosjean, N., Revest, J. M., Piazza, P. V., Koehl, M., et al. (2012). Adult-born neurons are necessary for extended contextual discrimination. Hippocampus 22, 292-298. doi:10.1002/hipo.20895
    • (2012) Hippocampus , vol.22 , pp. 292-298
    • Tronel, S.1    Belnoue, L.2    Grosjean, N.3    Revest, J.M.4    Piazza, P.V.5    Koehl, M.6
  • 39
    • 25444533023 scopus 로고    scopus 로고
    • Exercise enhances learning and hippocampal neurogenesis in aged mice
    • van Praag, H., Shubert, T., Zhao, C., and Gage, F. H. (2005). Exercise enhances learning and hippocampal neurogenesis in aged mice. J. Neurosci. 25, 8680-8685. doi:10.1523/JNEUROSCI.1731-05.2005.
    • (2005) J. Neurosci , vol.25 , pp. 8680-8685
    • Van Praag, H.1    Shubert, T.2    Zhao, C.3    Gage, F.H.4
  • 40
    • 84891701025 scopus 로고    scopus 로고
    • All about running:Synaptic plasticity, growth factors and adult hippocampal neurogenesis
    • Vivar, C., Potter, M. C., and van Praag, H. (2013). All about running:synaptic plasticity, growth factors and adult hippocampal neurogenesis. Curr. Top. Behav. Neurosci. 15, 189-210. doi:10.1007/7854_2012_220.
    • (2013) Curr. Top. Behav. Neurosci , vol.15 , pp. 189-210
    • Vivar, C.1    Potter, M.C.2    Van Praag, H.3
  • 41
    • 84884502539 scopus 로고    scopus 로고
    • Bridging animal and human models of exercise-induced brain plasticity
    • Voss, M. W., Vivar, C., Kramer, A. F., and van Praag, H. (2013). Bridging animal and human models of exercise-induced brain plasticity. Trends Cogn. Sci. 17, 525-544. doi:10.1016/j.tics.2013.08.001.
    • (2013) Trends Cogn. Sci , vol.17 , pp. 525-544
    • Voss, M.W.1    Vivar, C.2    Kramer, A.F.3    Van Praag, H.4
  • 42
    • 38949158786 scopus 로고    scopus 로고
    • Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells
    • Wang, J. W., David, D. J., Monckton, J. E., Battaglia, F., and Hen, R. (2008). Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells. J. Neurosci. 28, 1374-1384. doi:10.1523/JNEUROSCI.3632-07.2008.
    • (2008) J. Neurosci , vol.28 , pp. 1374-1384
    • Wang, J.W.1    David, D.J.2    Monckton, J.E.3    Battaglia, F.4    Hen, R.5
  • 43
    • 78549282823 scopus 로고    scopus 로고
    • Voluntary running prevents progressive memory decline and increases adult hippocampal neurogenesis and growth factor expression after whole-brain irradiation
    • Wong-Goodrich, S. J., Pfau, M. L., Flores, C. T., Fraser, J. A., Williams, C. L., and Jones, L. W. (2010). Voluntary running prevents progressive memory decline and increases adult hippocampal neurogenesis and growth factor expression after whole-brain irradiation. Cancer Res. 70, 9329-9338. doi:10.1158/0008-5472.CAN-10-1854.
    • (2010) Cancer Res , vol.70 , pp. 9329-9338
    • Wong-Goodrich, S.J.1    Pfau, M.L.2    Flores, C.T.3    Fraser, J.A.4    Williams, C.L.5    Jones, L.W.6
  • 44
    • 84902543503 scopus 로고    scopus 로고
    • Functional dissociation of adult-born neurons along the dorsoventral axis ofthe dentate gyrus
    • Wu, M. V., and Hen, R. (2014). Functional dissociation of adult-born neurons along the dorsoventral axis ofthe dentate gyrus. Hippocampus 24,751-761. doi:10.1002/hipo.22265.
    • (2014) Hippocampus , vol.24 , pp. 751-761
    • Wu, M.V.1    Hen, R.2
  • 45
    • 80051937468 scopus 로고    scopus 로고
    • Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults
    • Yassa, M. A., Lacy, J. W., Stark, S. M., Albert, M. S., Gallagher, M., and Stark, C. E. (2011). Pattern separation deficits associated with increased hippocampal CA3 and dentate gyrus activity in nondemented older adults. Hippocampus 21, 968-979. doi:10.1002/hipo.20808
    • (2011) Hippocampus , vol.21 , pp. 968-979
    • Yassa, M.A.1    Lacy, J.W.2    Stark, S.M.3    Albert, M.S.4    Gallagher, M.5    Stark, C.E.6


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