IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure

Cell

Volumn 172, Issue 1-2, 2018, Pages 218-233.e17

  Rajbhandari, Prashant ^a   Thomas, Brandon J ^a   Feng, An Chieh ^a   Hong, Cynthia ^a   Wang, Jiexin ^a   Vergnes, Laurent ^a   Sallam, Tamer ^a   Wang, Bo ^a   Sandhu, Jaspreet ^a   Seldin, Marcus M ^a   Lusis, Aldons J ^a   Fong, Loren G ^a   Katz, Melanie ^b   Lee, Richard ^b   Young, Stephen G ^a   Reue, Karen ^a   Smale, Stephen T ^a   Tontonoz, Peter ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ISIS PHARMACEUTICALS   (United States)

Author keywords

adipogenesis; IL 10; immunometabolism; thermogenesis

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR; CCAAT ENHANCER BINDING PROTEIN BETA; INTERLEUKIN 10 RECEPTOR ALPHA; INTERLEUKIN 10;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CHROMATIN IMMUNOPRECIPITATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; ENERGY EXPENDITURE; ENHANCER REGION; ENZYME REPRESSION; LIMIT OF QUANTITATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; RNA SEQUENCE; SIGNAL TRANSDUCTION; THERMOGENESIS; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINE; CHROMATIN ASSEMBLY AND DISASSEMBLY; ENERGY METABOLISM; GENETICS; METABOLISM;

ACTIVATING TRANSCRIPTION FACTORS; ADIPOCYTES; ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL LINE; CELLS, CULTURED; CHROMATIN ASSEMBLY AND DISASSEMBLY; ENERGY METABOLISM; INTERLEUKIN-10; MALE; MICE; MICE, INBRED C57BL; SIGNAL TRANSDUCTION; THERMOGENESIS;

EID: 85039067501     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.11.019     Document Type: Article

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