The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria

Cell

Volumn 166, Issue 2, 2016, Pages 424-435

  Long, Jonathan Z ^a,b   Svensson, Katrin J ^a,b   Bateman, Leslie A ^c   Lin, Hua ^d   Kamenecka, Theodore ^d   Lokurkar, Isha A ^a   Lou, Jesse ^a   Rao, Rajesh R ^a,b,e   Chang, Mi Ra ^d   Jedrychowski, Mark P ^a,b   Paulo, Joao A ^b   Gygi, Steven P ^b   Griffin, Patrick R ^d   Nomura, Daniel K ^c   Spiegelman, Bruce M ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; FATTY ACID; GLUCOSE; HYDROLASE; MITOCHONDRIAL PROTEIN; PEPTIDASE; PEPTIDASE M20 DOMAIN CONTAINING 1; RECOMBINANT ENZYME; SYNTHETASE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; AMIDASE; PM20D1 PROTEIN, MOUSE;

ADIPOCYTE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD; CHEMICAL INTERACTION; CONTROLLED STUDY; ENERGY EXPENDITURE; ENZYME ACTIVITY; ENZYME MECHANISM; GLUCOSE HOMEOSTASIS; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; MALE; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; PRIORITY JOURNAL; PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; CELL RESPIRATION; ENERGY METABOLISM; HOMEOSTASIS; METABOLISM; MITOCHONDRION; THERMOGENESIS;

ADIPOCYTES; AMIDOHYDROLASES; AMINO ACIDS; ANIMALS; CELL RESPIRATION; ENERGY METABOLISM; FATTY ACIDS; GLUCOSE; HOMEOSTASIS; MALE; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; THERMOGENESIS;

EID: 84978427707     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.05.071     Document Type: Article

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