-
1
-
-
79952793112
-
Obesity prevalence in the United States-up, down, or sideways?
-
Yanovski, SZ and Yanovski, JA (2011). Obesity prevalence in the United States-up, down, or sideways? N Engl J Med 364: 987-989.
-
(2011)
N Engl J Med
, vol.364
, pp. 987-989
-
-
Yanovski, S.Z.1
Yanovski, J.A.2
-
2
-
-
84887211753
-
-
http://www.cdc.gov/obesity/data/index.html.
-
-
-
-
3
-
-
0035856920
-
Global and societal implications of the diabetes epidemic
-
Zimmet, P, Alberti, KG and Shaw, J (2001). Global and societal implications of the diabetes epidemic. Nature 414: 782-787.
-
(2001)
Nature
, vol.414
, pp. 782-787
-
-
Zimmet, P.1
Alberti, K.G.2
Shaw, J.3
-
4
-
-
59249093414
-
Influence of race, ethnicity, and culture on childhood obesity: Implications for prevention and treatment: A consensus statement of Shaping America's Health and the Obesity Society
-
Caprio, S, Daniels, SR, Drewnowski, A, Kaufman, FR, Palinkas, LA, Rosenbloom, AL et al. (2008). Influence of race, ethnicity, and culture on childhood obesity: implications for prevention and treatment: a consensus statement of Shaping America's Health and the Obesity Society. Diabetes Care 31: 2211-2221.
-
(2008)
Diabetes Care
, vol.31
, pp. 2211-2221
-
-
Caprio, S.1
Daniels, S.R.2
Drewnowski, A.3
Kaufman, F.R.4
Palinkas, L.A.5
Rosenbloom, A.L.6
-
5
-
-
84866108680
-
Limitations in anti-obesity drug development: The critical role of hunger-promoting neurons
-
Dietrich, MO and Horvath, TL (2012). Limitations in anti-obesity drug development: the critical role of hunger-promoting neurons. Nat Rev Drug Discov 11: 675-691.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 675-691
-
-
Dietrich, M.O.1
Horvath, T.L.2
-
6
-
-
15544389362
-
Pathophysiology and long-term management of the metabolic syndrome
-
Pi-Sunyer, FX (2004). Pathophysiology and long-term management of the metabolic syndrome. Obes Res 12 (suppl.): 174S-180S.
-
(2004)
Obes Res
, vol.12
, Issue.SUPPL.
-
-
Pi-Sunyer, F.X.1
-
7
-
-
85030434746
-
Increased oxidative stress in obesity and its impact on metabolic syndrome
-
Furukawa, S, Fujita, T, Shimabukuro, M, Iwaki, M, Yamada, Y, Nakajima, Y et al. (2004). Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest 114: 1752-1761.
-
(2004)
J Clin Invest
, vol.114
, pp. 1752-1761
-
-
Furukawa, S.1
Fujita, T.2
Shimabukuro, M.3
Iwaki, M.4
Yamada, Y.5
Nakajima, Y.6
-
8
-
-
77955362775
-
Chronic inflammation in obesity and the metabolic syndrome
-
pii: 289645
-
Monteiro, R and Azevedo, I (2010). Chronic inflammation in obesity and the metabolic syndrome. Mediators Inflamm 2010: pii: 289645.
-
(2010)
Mediators Inflamm
, vol.2010
-
-
Monteiro, R.1
Azevedo, I.2
-
9
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu, H, Barnes, GT, Yang, Q, Tan, G, Yang, D, Chou, CJ et al. (2003). Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112: 1821-1830.
-
(2003)
J Clin Invest
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
-
10
-
-
0038283161
-
Interleukin-10 therapy-review of a new approach
-
Asadullah, K, Sterry, W and Volk, HD (2003). Interleukin-10 therapy-review of a new approach. Pharmacol Rev 55: 241-269.
-
(2003)
Pharmacol Rev
, vol.55
, pp. 241-269
-
-
Asadullah, K.1
Sterry, W.2
Volk, H.D.3
-
11
-
-
14644419628
-
Adipose tissue is a regulated source of interleukin-10
-
Juge-Aubry, CE, Somm, E, Pernin, A, Alizadeh, N, Giusti, V, Dayer, JM et al. (2005). Adipose tissue is a regulated source of interleukin-10. Cytokine 29: 270-274.
-
(2005)
Cytokine
, vol.29
, pp. 270-274
-
-
Juge-Aubry, C.E.1
Somm, E.2
Pernin, A.3
Alizadeh, N.4
Giusti, V.5
Dayer, J.M.6
-
12
-
-
27744434818
-
Association of interleukin-6, C-reactive protein, interleukin-10 and adiponectin plasma concentrations with measures of obesity, insulin sensitivity and glucose metabolism
-
Bluher, M, Fasshauer, M, Tonjes, A, Kratzsch, J, Schon, MR and Paschke, R (2005). Association of interleukin-6, C-reactive protein, interleukin-10 and adiponectin plasma concentrations with measures of obesity, insulin sensitivity and glucose metabolism. Exp Clin Endocrinol Diabetes 113: 534-537.
-
(2005)
Exp Clin Endocrinol Diabetes
, vol.113
, pp. 534-537
-
-
Bluher, M.1
Fasshauer, M.2
Tonjes, A.3
Kratzsch, J.4
Schon, M.R.5
Paschke, R.6
-
13
-
-
26244467653
-
Association between circulating adiponectin and interleukin-10 levels in android obesity: Effects of weight loss
-
Manigrasso, MR, Ferroni, P, Santilli, F, Taraborelli, T, Guagnano, MT, Michetti, N et al. (2005). Association between circulating adiponectin and interleukin-10 levels in android obesity: effects of weight loss. J Clin Endocrinol Metab 90: 5876-5879.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 5876-5879
-
-
Manigrasso, M.R.1
Ferroni, P.2
Santilli, F.3
Taraborelli, T.4
Guagnano, M.T.5
Michetti, N.6
-
14
-
-
33745304040
-
Variants of the interleukin-10 promoter gene are associated with obesity and insulin resistance but not type 2 diabetes in caucasian italian subjects
-
Scarpelli, D, Cardellini, M, Andreozzi, F, Laratta, E, Hribal, ML, Marini, MA et al. (2006). Variants of the interleukin-10 promoter gene are associated with obesity and insulin resistance but not type 2 diabetes in caucasian italian subjects. Diabetes 55: 1529-1533.
-
(2006)
Diabetes
, vol.55
, pp. 1529-1533
-
-
Scarpelli, D.1
Cardellini, M.2
Andreozzi, F.3
Laratta, E.4
Hribal, M.L.5
Marini, M.A.6
-
15
-
-
70350561703
-
Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle
-
Hong, EG, Ko, HJ, Cho, YR, Kim, HJ, Ma, Z, Yu, TY et al. (2009). Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle. Diabetes 58: 2525-2535.
-
(2009)
Diabetes
, vol.58
, pp. 2525-2535
-
-
Hong, E.G.1
Ko, H.J.2
Cho, Y.R.3
Kim, H.J.4
Ma, Z.5
Yu, T.Y.6
-
16
-
-
84862154208
-
Interleukin-10 expression induced by adeno-associated virus vector suppresses proteinuria in Zucker obese rats
-
Ogura, M, Urabe, M, Akimoto, T, Onishi, A, Ito, C, Ito, T et al. (2012). Interleukin-10 expression induced by adeno-associated virus vector suppresses proteinuria in Zucker obese rats. Gene Ther 19: 476-482.
-
(2012)
Gene Ther
, vol.19
, pp. 476-482
-
-
Ogura, M.1
Urabe, M.2
Akimoto, T.3
Onishi, A.4
Ito, C.5
Ito, T.6
-
17
-
-
33748754038
-
Endogenous interleukin-10 protects against hepatic steatosis but does not improve insulin sensitivity during high-fat feeding in mice
-
den Boer, MA, Voshol, PJ, Schroder-van der Elst, JP, Korsheninnikova, E, Ouwens, DM, Kuipers, F et al. (2006). Endogenous interleukin-10 protects against hepatic steatosis but does not improve insulin sensitivity during high-fat feeding in mice. Endocrinology 147: 4553-4558.
-
(2006)
Endocrinology
, vol.147
, pp. 4553-4558
-
-
Den Boer, M.A.1
Voshol, P.J.2
Schroder-Van Der Elst, J.P.3
Korsheninnikova, E.4
Ouwens, D.M.5
Kuipers, F.6
-
18
-
-
39849107173
-
Interleukin-10 is a protective factor against diet-induced insulin resistance in liver
-
Cintra, DE, Pauli, JR, Araujo, EP, Moraes, JC, de Souza, CT, Milanski, M et al. (2008). Interleukin-10 is a protective factor against diet-induced insulin resistance in liver. J Hepatol 48: 628-637.
-
(2008)
J Hepatol
, vol.48
, pp. 628-637
-
-
Cintra, D.E.1
Pauli, J.R.2
Araujo, E.P.3
Moraes, J.C.4
De Souza, C.T.5
Milanski, M.6
-
19
-
-
74049092099
-
The role of proliferator-activated receptor gamma coactivator-1alpha in the fatty-aciddependent transcriptional control of interleukin-10 in hepatic cells of rodents
-
Morari, J, Torsoni, AS, Anhe, GF, Roman, EA, Cintra, DE, Ward, LS et al. (2010). The role of proliferator-activated receptor gamma coactivator-1alpha in the fatty-aciddependent transcriptional control of interleukin-10 in hepatic cells of rodents. Metab Clin Exp 59: 215-223.
-
(2010)
Metab Clin Exp
, vol.59
, pp. 215-223
-
-
Morari, J.1
Torsoni, A.S.2
Anhe, G.F.3
Roman, E.A.4
Cintra, D.E.5
Ward, L.S.6
-
20
-
-
53549101295
-
Interleukin-10 to tumor necrosis factor-alpha ratio is a predictive biomarker in nonalcoholic fatty liver disease: Interleukin-10 to tumor necrosis factor-alpha ratio in steatohepatitis
-
Hashem, RM, Mahmoud, MF, El-Moselhy, MA and Soliman, HM (2008). Interleukin-10 to tumor necrosis factor-alpha ratio is a predictive biomarker in nonalcoholic fatty liver disease: interleukin-10 to tumor necrosis factor-alpha ratio in steatohepatitis. Eur J Gastroenterol Hepatol 20: 995-1001.
-
(2008)
Eur J Gastroenterol Hepatol
, vol.20
, pp. 995-1001
-
-
Hashem, R.M.1
Mahmoud, M.F.2
El-Moselhy, M.A.3
Soliman, H.M.4
-
21
-
-
84871686339
-
Spleen-derived interleukin-10 downregulates the severity of high-fat diet-induced non-alcoholic fatty pancreas disease
-
Gotoh, K, Inoue, M, Shiraishi, K, Masaki, T, Chiba, S, Mitsutomi, K et al. (2012). Spleen-derived interleukin-10 downregulates the severity of high-fat diet-induced non-alcoholic fatty pancreas disease. PLoS ONE 7: e53154.
-
(2012)
PLoS ONE
, vol.7
-
-
Gotoh, K.1
Inoue, M.2
Shiraishi, K.3
Masaki, T.4
Chiba, S.5
Mitsutomi, K.6
-
22
-
-
0036224269
-
Low production capacity of interleukin-10 associates with the metabolic syndrome and type 2 diabetes: The Leiden 85-Plus Study
-
van Exel, E, Gussekloo, J, de Craen, AJ, Frolich, M, Bootsma-Van Der Wiel, A and Westendorp, RG; Leiden 85 Plus Study (2002). Low production capacity of interleukin-10 associates with the metabolic syndrome and type 2 diabetes: the Leiden 85-Plus Study. Diabetes 51: 1088-1092.
-
(2002)
Diabetes
, vol.51
, pp. 1088-1092
-
-
Van Exel, E.1
Gussekloo, J.2
De Craen, A.J.3
Frolich, M.4
Bootsma-Van Der Wiel, A.5
Westendorp, R.G.6
Study Plus, L.7
-
23
-
-
50949108719
-
Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice
-
Murano, I, Barbatelli, G, Parisani, V, Latini, C, Muzzonigro, G, Castellucci, M et al. (2008). Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice. J Lipid Res 49: 1562-1568.
-
(2008)
J Lipid Res
, vol.49
, pp. 1562-1568
-
-
Murano, I.1
Barbatelli, G.2
Parisani, V.3
Latini, C.4
Muzzonigro, G.5
Castellucci, M.6
-
24
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
Shi, H, Kokoeva, MV, Inouye, K, Tzameli, I, Yin, H and Flier, JS (2006). TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 116: 3015-3025.
-
(2006)
J Clin Invest
, vol.116
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
Tzameli, I.4
Yin, H.5
Flier, J.S.6
-
25
-
-
84856957894
-
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
-
Henao-Mejia, J, Elinav, E, Jin, C, Hao, L, Mehal, WZ, Strowig, T et al. (2012). Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature 482: 179-185.
-
(2012)
Nature
, vol.482
, pp. 179-185
-
-
Henao-Mejia, J.1
Elinav, E.2
Jin, C.3
Hao, L.4
Mehal, W.Z.5
Strowig, T.6
-
26
-
-
80053087484
-
Inflammasome is a central player in the induction of obesity and insulin resistance
-
Stienstra, R, van Diepen, JA, Tack, CJ, Zaki, MH, van de Veerdonk, FL, Perera, D et al. (2011). Inflammasome is a central player in the induction of obesity and insulin resistance. Proc Natl Acad Sci USA 108: 15324-15329.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 15324-15329
-
-
Stienstra, R.1
Van Diepen, J.A.2
Tack, C.J.3
Zaki, M.H.4
Van De Veerdonk, F.L.5
Perera, D.6
-
27
-
-
0032805251
-
Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
-
Liu, F, Song, Y and Liu, D (1999). Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther 6: 1258-1266.
-
(1999)
Gene Ther
, vol.6
, pp. 1258-1266
-
-
Liu, F.1
Song, Y.2
Liu, D.3
-
28
-
-
0033166561
-
High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA
-
Zhang, G, Budker, V and Wolff, JA (1999). High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA. Hum Gene Ther 10: 1735-1737.
-
(1999)
Hum Gene Ther
, vol.10
, pp. 1735-1737
-
-
Zhang, G.1
Budker, V.2
Wolff, J.A.3
-
29
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak, KJ and Schmittgen, TD (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
30
-
-
70449718904
-
Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice
-
Hirata, A, Maeda, N, Hiuge, A, Hibuse, T, Fujita, K, Okada, T et al. (2009). Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice. Cardiovasc Res 84: 164-172.
-
(2009)
Cardiovasc Res
, vol.84
, pp. 164-172
-
-
Hirata, A.1
Maeda, N.2
Hiuge, A.3
Hibuse, T.4
Fujita, K.5
Okada, T.6
-
31
-
-
0018128226
-
Lipid extraction of tissues with a low-toxicity solvent
-
Hara, A and Radin, NS (1978). Lipid extraction of tissues with a low-toxicity solvent. Anal Biochem 90: 420-426.
-
(1978)
Anal Biochem
, vol.90
, pp. 420-426
-
-
Hara, A.1
Radin, N.S.2
|