Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors

Nature Communications

Volumn 8, Issue 1, 2017, Pages

  Sisquella, Xavier ^a,b   Ofir Birin, Yifat ^c   Pimentel, Matthew A ^a,b   Cheng, Lesley ^d,e   Abou Karam, Paula ^c   Sampaio, Natália G ^a,b   Penington, Jocelyn Sietsma ^a   Connolly, Dympna ^f   Giladi, Tal ^c   Scicluna, Benjamin J ^d,e   Sharples, Robyn A ^d,e   Waltmann, Andreea ^a,b   Avni, Dror ^g   Schwartz, Eli ^g,h   Schofield, Louis ^a,b,i   Porat, Ziv ^c   Hansen, Diana S ^a,b   Papenfuss, Anthony T ^a,b   Eriksson, Emily M ^a,b   Gerlic, Motti ^h   Hill, Andrew F ^d,e   Bowie, Andrew G ^f   Regev Rudzki, Neta ^c   more..

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e LA TROBE UNIVERSITY   (Australia)

^f TRINITY COLLEGE DUBLIN   (Ireland)

^g SHEBA MEDICAL CENTER   (Israel)

^h TEL AVIV UNIVERSITY   (Israel)

ⁱ JAMES COOK UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA BINDING PROTEIN; GENOMIC DNA; INTERFERON REGULATORY FACTOR 3; PARASITE DNA; RIBOSOME RNA; TRANSFER RNA; UNCLASSIFIED DRUG; IRF3 PROTEIN, HUMAN; MEMBRANE PROTEIN; MPYS PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; PROTOZOAL DNA; PROTOZOAL RNA; TBK1 PROTEIN, HUMAN;

BLOOD; CELL; CELL COMPONENT; DISEASE TREATMENT; DNA; ENZYME; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC ANALYSIS; GENOMICS; MALARIA; MOSQUITO; PARASITE; PATHOGEN; PROTEIN; RNA; VIRULENCE;

ARTICLE; CELL COMMUNICATION; CELL DENSITY; CELL DIFFERENTIATION; CELLULAR SECRETION; CONTROLLED STUDY; CYTOSOL; ERYTHROCYTE; EXOSOME; GENE INDUCTION; HOST CELL; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; INNATE IMMUNITY; INTERNALIZATION; MALARIA; MONOCYTE; NONHUMAN; NORMAL HUMAN; PARASITE VIRULENCE; PLASMODIUM FALCIPARUM; TRANSMISSION ELECTRON MICROSCOPY; CELL LINE; CELL NUCLEUS; CRYOELECTRON MICROSCOPY; GENETICS; IMMUNOLOGY; MALARIA FALCIPARUM; METABOLISM; PARASITOLOGY; PATHOGENICITY; PHOSPHORYLATION; PRIMARY CELL CULTURE; SECRETION (PROCESS); SIGNAL TRANSDUCTION; ULTRASTRUCTURE;

PLASMODIUM FALCIPARUM;

CELL LINE; CELL NUCLEUS; CRYOELECTRON MICROSCOPY; CYTOSOL; DNA, PROTOZOAN; ERYTHROCYTES; EXTRACELLULAR VESICLES; HUMANS; IMMUNITY, INNATE; INTERFERON REGULATORY FACTOR-3; MALARIA, FALCIPARUM; MEMBRANE PROTEINS; MONOCYTES; PHOSPHORYLATION; PLASMODIUM FALCIPARUM; PRIMARY CELL CULTURE; PROTEIN-SERINE-THREONINE KINASES; RNA, PROTOZOAN; SIGNAL TRANSDUCTION;

EID: 85038077958     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-02083-1     Document Type: Article

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