Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality

Immunity

Volumn 45, Issue 5, 2016, Pages 1093-1107

  Yu, Xiao ^a,c   Cai, Baowei ^c,d   Wang, Mingjun ^b,c   Tan, Peng ^c,g   Ding, Xilai ^c   Wu, Jian ^e   Li, Jian ^d   Li, Qingtian ^c   Liu, Pinghua ^c   Xing, Changsheng ^c   Wang, Helen Y ^c   Su, Xin zhuan ^d,e   Wang, Rong Fu ^c,f,g  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^d XIAMEN UNIVERSITY   (China)

^e NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

^g TEXAS A M COLLEGE OF MEDICINE   (United States)

Author keywords

Innate immune response; Malaria infection; Plasmacytoid dendritic cells; Type I IFN signaling

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; GENOMIC DNA; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; MYELOID DIFFERENTIATION FACTOR 88; SUPPRESSOR OF CYTOKINE SIGNALING 1; TOLL LIKE RECEPTOR 7; INTERFERON;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENETIC CODE; HOST; IMMUNOREGULATION; IN VIVO STUDY; MACROPHAGE; MORTALITY; MOUSE; NEWBORN; NONHUMAN; PARASITE IMMUNITY; PLASMACYTOID DENDRITIC CELL; PLASMODIUM YOELII; PLASMODIUM YOELII INFECTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ADAPTIVE IMMUNITY; ANIMAL; DENDRITIC CELL; DISEASE MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE SILENCING; IMMUNOLOGY; KNOCKOUT MOUSE; MALARIA; POLYMERASE CHAIN REACTION;

ADAPTIVE IMMUNITY; ANIMALS; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE KNOCKDOWN TECHNIQUES; INTERFERON TYPE I; MALARIA; MICE; MICE, KNOCKOUT; PLASMODIUM YOELII; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84999885091     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.10.001     Document Type: Article

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