-
1
-
-
0033545342
-
Acute-phase proteins and other systemic responses to inflammation
-
Gabay, C. & Kushner, I. Acute-phase proteins and other systemic responses to inflammation. N. Engl. J. Med. 340, 448-54 (1999).
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 448-454
-
-
Gabay, C.1
Kushner, I.2
-
2
-
-
84860250390
-
Hepatic acute phase proteins-Regulation by IL-6-and IL-1-Type cytokines involving STAT3 and its crosstalk with NF-kappaB-dependent signaling
-
Bode, J. G., Albrecht, U., Haussinger, D., Heinrich, P. C. & Schaper, F. Hepatic acute phase proteins-regulation by IL-6-and IL-1-Type cytokines involving STAT3 and its crosstalk with NF-kappaB-dependent signaling. Eur. J. Cell Biol. 91, 496-505 (2012).
-
(2012)
Eur. J. Cell Biol.
, vol.91
, pp. 496-505
-
-
Bode, J.G.1
Albrecht, U.2
Haussinger, D.3
Heinrich, P.C.4
Schaper, F.5
-
3
-
-
84966431031
-
Hepatocytes: A key cell type for innate immunity
-
Zhou, Z., Xu, M. J. & Gao, B. Hepatocytes: A key cell type for innate immunity. Cell Mol. Immunol. 13, 301-15 (2016).
-
(2016)
Cell Mol. Immunol.
, vol.13
, pp. 301-315
-
-
Zhou, Z.1
Xu, M.J.2
Gao, B.3
-
4
-
-
84953314438
-
Hepatocytes as immunological agents
-
Crispe, I. N. Hepatocytes as immunological agents. J. Immunol. 196, 17-21 (2016).
-
(2016)
J. Immunol.
, vol.196
, pp. 17-21
-
-
Crispe, I.N.1
-
5
-
-
84901820722
-
Role of interleukins in obesity: Implications for metabolic disease
-
Febbraio, M. A. Role of interleukins in obesity: implications for metabolic disease. Trends Endocrinol. Metab. 25, 312-9 (2014).
-
(2014)
Trends Endocrinol. Metab.
, vol.25
, pp. 312-319
-
-
Febbraio, M.A.1
-
6
-
-
79151478555
-
Type 2 diabetes as an inflammatory disease
-
Donath, M. Y. & Shoelson, S. E. Type 2 diabetes as an inflammatory disease. Nat. Rev. Immunol. 11, 98-107 (2011).
-
(2011)
Nat. Rev. Immunol.
, vol.11
, pp. 98-107
-
-
Donath, M.Y.1
Shoelson, S.E.2
-
7
-
-
79751492851
-
NF-kappaB in the liver-Linking injury, fibrosis and hepatocellular carcinoma
-
Luedde, T. & Schwabe, R. F. NF-kappaB in the liver-linking injury, fibrosis and hepatocellular carcinoma. Nat. Rev. Gastroenterol Hepatol. 8, 108-18 (2011).
-
(2011)
Nat Rev Gastroenterol Hepatol
, vol.8
, pp. 108-118
-
-
Luedde, T.1
Schwabe, R.F.2
-
8
-
-
84963541541
-
IL-6 pathway in the liver: From physiopathology to therapy
-
Schmidt-Arras, D. & Rose-John, S. IL-6 pathway in the liver: From physiopathology to therapy. J. Hepatol. 64, 1403-15 (2016).
-
(2016)
J. Hepatol.
, vol.64
, pp. 1403-1415
-
-
Schmidt-Arras, D.1
Rose-John, S.2
-
9
-
-
84860587432
-
Hepatocyte-specific mutation of both NF-kappaB RelA and STAT3 abrogates the acute phase response in mice
-
Quinton, L. J. et al. Hepatocyte-specific mutation of both NF-kappaB RelA and STAT3 abrogates the acute phase response in mice. J. Clin. Invest. 122, 1758-63 (2012).
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1758-1763
-
-
Quinton, L.J.1
-
10
-
-
0035131190
-
Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver
-
Alonzi, T. et al. Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver. Mol. Cell. Biol. 21, 1621-32 (2001).
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 1621-1632
-
-
Alonzi, T.1
-
11
-
-
77954399377
-
Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function
-
Sander, L. E. et al. Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function. J. Exp. Med. 207, 1453-64 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1453-1464
-
-
Sander, L.E.1
-
12
-
-
66549093853
-
Mechanisms of the hepatic acute-phase response during bacterial pneumonia
-
Quinton, L. J., Jones, M. R., Robson, B. E. & Mizgerd, J. P. Mechanisms of the hepatic acute-phase response during bacterial pneumonia. Infect. Immun. 77, 2417-26 (2009).
-
(2009)
Infect. Immun.
, vol.77
, pp. 2417-2426
-
-
Quinton, L.J.1
Jones, M.R.2
Robson, B.E.3
Mizgerd, J.P.4
-
13
-
-
0030589152
-
Initiation of acute phase response and synthesis of cytokines
-
Koj, A. Initiation of acute phase response and synthesis of cytokines. Biochim. Biophys. Acta 1317, 84-94 (1996).
-
(1996)
Biochim. Biophys. Acta
, vol.1317
, pp. 84-94
-
-
Koj, A.1
-
14
-
-
79960918745
-
Metabolic nuclear receptor signaling and the inflammatory acute phase response
-
Venteclef, N., Jakobsson, T., Steffensen, K. R. & Treuter, E. Metabolic nuclear receptor signaling and the inflammatory acute phase response. Trends Endocrinol. Metab. 22, 333-43 (2011).
-
(2011)
Trends Endocrinol. Metab.
, vol.22
, pp. 333-343
-
-
Venteclef, N.1
Jakobsson, T.2
Steffensen, K.R.3
Treuter, E.4
-
15
-
-
0034887798
-
Gene transcription in hepatocytes during the acute phase of a systemic inflammation: From transcription factors to target genes
-
Ruminy, P. et al. Gene transcription in hepatocytes during the acute phase of a systemic inflammation: from transcription factors to target genes. Inflamm. Res. 50, 383-90 (2001).
-
(2001)
Inflamm. Res.
, vol.50
, pp. 383-390
-
-
Ruminy, P.1
-
16
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
Yu, H., Pardoll, D. & Jove, R. STATs in cancer inflammation and immunity: A leading role for STAT3. Nat. Rev. Cancer 9, 798-809 (2009).
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
17
-
-
79151473780
-
NF-kappaB and STAT3 signaling hubs for lung innate immunity
-
Quinton, L. J. & Mizgerd, J. P. NF-kappaB and STAT3 signaling hubs for lung innate immunity. Cell Tissue Res. 343, 153-65 (2011).
-
(2011)
Cell Tissue Res.
, vol.343
, pp. 153-165
-
-
Quinton, L.J.1
Mizgerd, J.P.2
-
18
-
-
34249868449
-
Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB
-
Yang, J. et al. Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB. Genes Dev. 21, 1396-408 (2007).
-
(2007)
Genes Dev.
, vol.21
, pp. 1396-1408
-
-
Yang, J.1
-
19
-
-
0036797750
-
Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB
-
Yu, Z., Zhang, W. & Kone, B. C. Signal transducers and activators of transcription 3 (STAT3) inhibits transcription of the inducible nitric oxide synthase gene by interacting with nuclear factor kappaB. Biochem. J. 367, 97-105 (2002).
-
(2002)
Biochem. J.
, vol.367
, pp. 97-105
-
-
Yu, Z.1
Zhang, W.2
Kone, B.C.3
-
20
-
-
63249092765
-
Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors
-
Lee, H. et al. Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors. Cancer Cell 15, 283-93 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 283-293
-
-
Lee, H.1
-
21
-
-
85009841534
-
Nuclear translocation of STAT3 and NF-kappaB are independent of each other but NF-kappaB supports expression and activation of STAT3
-
Martincuks, A. et al. Nuclear translocation of STAT3 and NF-kappaB are independent of each other but NF-kappaB supports expression and activation of STAT3. Cell Signal. 32, 36-47 (2017).
-
(2017)
Cell Signal.
, vol.32
, pp. 36-47
-
-
Martincuks, A.1
-
22
-
-
84899450857
-
Transcriptional enhancers: From properties to genome-wide predictions
-
Shlyueva, D., Stampfel, G. & Stark, A. Transcriptional enhancers: from properties to genome-wide predictions. Nat. Rev. Genet. 15, 272-286 (2014).
-
(2014)
Nat. Rev.Genet.
, vol.15
, pp. 272-286
-
-
Shlyueva, D.1
Stampfel, G.2
Stark, A.3
-
23
-
-
77949971595
-
Selective transcription in response to an inflammatory stimulus
-
Smale, S. T. Selective transcription in response to an inflammatory stimulus. Cell 140, 833-844 (2010).
-
(2010)
Cell
, vol.140
, pp. 833-844
-
-
Smale, S.T.1
-
24
-
-
84959346645
-
Inducible chromatin priming is associated with the establishment of immunological memory in T cells
-
Bevington, S. L. et al. Inducible chromatin priming is associated with the establishment of immunological memory in T cells. EMBO. J. 35, 515-535 (2016).
-
(2016)
EMBO. J.
, vol.35
, pp. 515-535
-
-
Bevington, S.L.1
-
25
-
-
84908425487
-
Transcriptional control of inflammatory responses
-
Smale, S. T. & Natoli, G. Transcriptional control of inflammatory responses. Cold Spring Harb. Perspect Biol. 6, a016261 (2014).
-
(2014)
Cold Spring Harb. Perspect Biol
, vol.6
, pp. a016261
-
-
Smale, S.T.1
Natoli, G.2
-
26
-
-
84892800329
-
Dynamic regulation of transcriptional states by chromatin and transcription factors
-
Voss, T. C. & Hager, G. L. Dynamic regulation of transcriptional states by chromatin and transcription factors. Nat. Rev. Genet. 15, 69-81 (2014).
-
(2014)
Nat. Rev.Genet.
, vol.15
, pp. 69-81
-
-
Voss, T.C.1
Hager, G.L.2
-
27
-
-
84964555664
-
Chromatin structure and gene regulation: A dynamic view of enhancer function
-
Stavreva, D. A. & Hager, G. L. Chromatin structure and gene regulation: A dynamic view of enhancer function. Nucleus 6, 442-448 (2015).
-
(2015)
Nucleus
, vol.6
, pp. 442-448
-
-
Stavreva, D.A.1
Hager, G.L.2
-
28
-
-
80052000538
-
Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism
-
Voss, T. C. et al. Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism. Cell 146, 544-554 (2011).
-
(2011)
Cell
, vol.146
, pp. 544-554
-
-
Voss, T.C.1
-
29
-
-
84992446138
-
Pioneer factors and ATP-dependent chromatin remodeling factors interact dynamically: A new perspective: Multiple transcription factors can effect chromatin pioneer functions through dynamic interactions with ATP-dependent chromatin remodeling factors
-
Swinstead, E. E., Paakinaho, V., Presman, D. M. & Hager, G. L. Pioneer factors and ATP-dependent chromatin remodeling factors interact dynamically: A new perspective: Multiple transcription factors can effect chromatin pioneer functions through dynamic interactions with ATP-dependent chromatin remodeling factors. Bioessays 38, 1150-1157 (2016).
-
(2016)
Bioessays
, vol.38
, pp. 1150-1157
-
-
Swinstead, E.E.1
Paakinaho, V.2
Presman, D.M.3
Hager, G.L.4
-
30
-
-
79959911826
-
Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding
-
Biddie, S. C. et al. Transcription factor AP1 potentiates chromatin accessibility and glucocorticoid receptor binding. Mol. Cell 43, 145-155 (2011).
-
(2011)
Mol. Cell
, vol.43
, pp. 145-155
-
-
Biddie, S.C.1
-
31
-
-
84878547373
-
C/EBP maintains chromatin accessibility in liver and facilitates glucocorticoid receptor recruitment to steroid response elements
-
Grontved, L. et al. C/EBP maintains chromatin accessibility in liver and facilitates glucocorticoid receptor recruitment to steroid response elements. EMBO J 32, 1568-1583 (2013).
-
(2013)
EMBO J
, vol.32
, pp. 1568-1583
-
-
Grontved, L.1
-
32
-
-
84882600977
-
Reprogramming of the chromatin landscape: Interplay of the estrogen and glucocorticoid receptors at the genomic level
-
Miranda, T. B. et al. Reprogramming of the chromatin landscape: interplay of the estrogen and glucocorticoid receptors at the genomic level. Cancer Res. 73, 5130-5139 (2013).
-
(2013)
Cancer Res.
, vol.73
, pp. 5130-5139
-
-
Miranda, T.B.1
-
33
-
-
84894235553
-
Peroxisome proliferator-Activated receptor gamma and C/EBPalpha synergistically activate key metabolic adipocyte genes by assisted loading
-
Madsen, M. S., Siersbaek, R., Boergesen, M., Nielsen, R. & Mandrup, S. Peroxisome proliferator-Activated receptor gamma and C/EBPalpha synergistically activate key metabolic adipocyte genes by assisted loading. Mol. Cell. Biol. 34, 939-954 (2014).
-
(2014)
Mol. Cell. Biol.
, vol.34
, pp. 939-954
-
-
Madsen, M.S.1
Siersbaek, R.2
Boergesen, M.3
Nielsen, R.4
Mandrup, S.5
-
34
-
-
84934325147
-
Genetic variation determines PPARgamma function and anti-diabetic drug response in vivo
-
Soccio, R. E. et al. Genetic variation determines PPARgamma function and anti-diabetic drug response in vivo. Cell 162, 33-44 (2015).
-
(2015)
Cell
, vol.162
, pp. 33-44
-
-
Soccio, R.E.1
-
35
-
-
84962630625
-
Steroid receptors reprogram FoxA1 occupancy through dynamic chromatin transitions
-
Swinstead, E. E. et al. Steroid receptors reprogram FoxA1 occupancy through dynamic chromatin transitions. Cell 165, 593-605 (2016).
-
(2016)
Cell
, vol.165
, pp. 593-605
-
-
Swinstead, E.E.1
-
36
-
-
84952871218
-
Coactivator-dependent oscillation of chromatin accessibility dictates circadian gene amplitude via REV-ERB loading
-
Zhu, B. et al. Coactivator-dependent oscillation of chromatin accessibility dictates circadian gene amplitude via REV-ERB loading. Mol. Cell 60, 769-83 (2015).
-
(2015)
Mol. Cell
, vol.60
, pp. 769-783
-
-
Zhu, B.1
-
37
-
-
85016485849
-
Transcription factor assisted loading and enhancer dynamics dictate the hepatic fasting response
-
Goldstein, I. et al. Transcription factor assisted loading and enhancer dynamics dictate the hepatic fasting response. Genome Res. 27, 427-439 (2017).
-
(2017)
Genome Res.
, vol.27
, pp. 427-439
-
-
Goldstein, I.1
-
38
-
-
84884829249
-
Mapping human epigenomes
-
Rivera, C. M. & Ren, B. Mapping human epigenomes. Cell 155, 39-55 (2013).
-
(2013)
Cell
, vol.155
, pp. 39-55
-
-
Rivera, C.M.1
Ren, B.2
-
39
-
-
78650758676
-
Histone H3K27ac separates active from poised enhancers and predicts developmental state
-
Creyghton, M. P. et al. Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc. Natl Acad. Sci. USA 107, 21931-21936 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 21931-21936
-
-
Creyghton, M.P.1
-
40
-
-
84865755978
-
The accessible chromatin landscape of the human genome
-
Thurman, R. E. et al. The accessible chromatin landscape of the human genome. Nature 489, 75-82 (2012).
-
(2012)
Nature
, vol.489
, pp. 75-82
-
-
Thurman, R.E.1
-
41
-
-
84904395679
-
Proteomic and genomic studies of non-Alcoholic fatty liver disease-Clues in the pathogenesis
-
Lim, J. W., Dillon, J. & Miller, M. Proteomic and genomic studies of non-Alcoholic fatty liver disease-clues in the pathogenesis. World J. Gastroenterol. 20, 8325-40 (2014).
-
(2014)
World J. Gastroenterol.
, vol.20
, pp. 8325-8340
-
-
Lim, J.W.1
Dillon, J.2
Miller, M.3
-
42
-
-
73249130002
-
Serum levels of proinflammatory cytokines interleukin-1beta, interleukin-6, and tumor necrosis factor alpha in mixed cryoglobulinemia
-
Antonelli, A. et al. Serum levels of proinflammatory cytokines interleukin-1beta, interleukin-6, and tumor necrosis factor alpha in mixed cryoglobulinemia. Arthritis Rheum. 60, 3841-7 (2009).
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 3841-3847
-
-
Antonelli, A.1
-
43
-
-
77952367798
-
Widespread transcription at neuronal activity-regulated enhancers
-
Kim, T. K. et al. Widespread transcription at neuronal activity-regulated enhancers. Nature 465, 182-187 (2010).
-
(2010)
Nature
, vol.465
, pp. 182-187
-
-
Kim, T.K.1
-
44
-
-
77952908743
-
A large fraction of extragenic RNA pol II transcription sites overlap enhancers
-
De Santa, F. et al. A large fraction of extragenic RNA pol II transcription sites overlap enhancers. PLoS Biol. 8, e1000384 (2010).
-
(2010)
PLoS Biol.
, vol.8
, pp. e1000384
-
-
De Santa, F.1
-
45
-
-
33646547951
-
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4
-
Gilchrist, M. et al. Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4. Nature 441, 173-8 (2006).
-
(2006)
Nature
, vol.441
, pp. 173-178
-
-
Gilchrist, M.1
-
46
-
-
84905970514
-
Metformin suppresses lipopolysaccharide (LPS)-induced inflammatory response in murine macrophages via activating transcription factor-3 (ATF-3) induction
-
Kim, J. et al. Metformin suppresses lipopolysaccharide (LPS)-induced inflammatory response in murine macrophages via activating transcription factor-3 (ATF-3) induction. J. Biol. Chem. 289, 23246-55 (2014).
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 23246-23255
-
-
Kim, J.1
-
47
-
-
36348995922
-
Signal transducer and activator of transcription 3 signaling within hepatocytes attenuates systemic inflammatory response and lethality in septic mice
-
Sakamori, R. et al. Signal transducer and activator of transcription 3 signaling within hepatocytes attenuates systemic inflammatory response and lethality in septic mice. Hepatology 46, 1564-73 (2007).
-
(2007)
Hepatology
, vol.46
, pp. 1564-1573
-
-
Sakamori, R.1
-
48
-
-
84922480037
-
Regulation of RNA polymerase II activation by histone acetylation in single living cells
-
Stasevich, T. J. et al. Regulation of RNA polymerase II activation by histone acetylation in single living cells. Nature 516, 272-275(2014).
-
(2014)
Nature
, vol.516
, pp. 272-275
-
-
Stasevich, T.J.1
-
49
-
-
65549104157
-
Histone modifications at human enhancers reflect global cell-Type-specific gene expression
-
Heintzman, N. D. et al. Histone modifications at human enhancers reflect global cell-Type-specific gene expression. Nature 459, 108-112 (2009).
-
(2009)
Nature
, vol.459
, pp. 108-112
-
-
Heintzman, N.D.1
-
50
-
-
79951516056
-
A unique chromatin signature uncovers early developmental enhancers in humans
-
Rada-Iglesias, A. et al. A unique chromatin signature uncovers early developmental enhancers in humans. Nature 470, 279-283 (2011).
-
(2011)
Nature
, vol.470
, pp. 279-283
-
-
Rada-Iglesias, A.1
-
51
-
-
84958191207
-
Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells
-
Soucie, E. L. et al. Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells. Science 351, aad5510 (2016).
-
(2016)
Science
, vol.351
, pp. aad5510
-
-
Soucie, E.L.1
-
52
-
-
84929135130
-
Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers
-
Hilton, I. B. et al. Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. Nat. Biotechnol. 33, 510-7 (2015).
-
(2015)
Nat. Biotechnol.
, vol.33
, pp. 510-517
-
-
Hilton, I.B.1
-
53
-
-
0032039076
-
Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
-
Zhong, H., Voll, R. E. & Ghosh, S. Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol. Cell 1, 661-71 (1998).
-
(1998)
Mol. Cell
, vol.1
, pp. 661-671
-
-
Zhong, H.1
Voll, R.E.2
Ghosh, S.3
-
54
-
-
84923349602
-
The activation of IL-1-induced enhancers depends on TAK1 kinase activity and NF-kappaB p65
-
S2211-1247(15)00002-9
-
Jurida, L. et al. The activation of IL-1-induced enhancers depends on TAK1 kinase activity and NF-kappaB p65. Cell Rep. pii: S2211-1247(15)00002-9. doi: 10.1016/j.celrep.2015.01.001 (2015).
-
(2015)
Cell Rep
-
-
Jurida, L.1
-
55
-
-
84908602740
-
NF-kappaB directs dynamic super enhancer formation in inflammation and atherogenesis
-
Brown, J. D. et al. NF-kappaB directs dynamic super enhancer formation in inflammation and atherogenesis. Mol. Cell 56, 219-31 (2014).
-
(2014)
Mol. Cell
, vol.56
, pp. 219-231
-
-
Brown, J.D.1
-
56
-
-
84872522528
-
Latent enhancers activated by stimulation in differentiated cells
-
Ostuni, R. et al. Latent enhancers activated by stimulation in differentiated cells. Cell 152, 157-71 (2013).
-
(2013)
Cell
, vol.152
, pp. 157-171
-
-
Ostuni, R.1
-
57
-
-
84884355522
-
Synergistic activation of inflammatory cytokine genes by interferon-gamma-induced chromatin remodeling and toll-like receptor signaling
-
Qiao, Y. et al. Synergistic activation of inflammatory cytokine genes by interferon-gamma-induced chromatin remodeling and toll-like receptor signaling. Immunity 39, 454-69 (2013).
-
(2013)
Immunity
, vol.39
, pp. 454-469
-
-
Qiao, Y.1
-
58
-
-
80455144479
-
Pioneer transcription factors: Establishing competence for gene expression
-
Zaret, K. S. & Carroll, J. S. Pioneer transcription factors: establishing competence for gene expression. Genes Dev. 25, 2227-2241 (2011).
-
(2011)
Genes Dev.
, vol.25
, pp. 2227-2241
-
-
Zaret, K.S.1
Carroll, J.S.2
-
60
-
-
85018462823
-
The pioneer factor OCT4 requires the chromatin remodeller BRG1 to support gene regulatory element function in mouse embryonic stem cells
-
King, H. W. & Klose, R. J. The pioneer factor OCT4 requires the chromatin remodeller BRG1 to support gene regulatory element function in mouse embryonic stem cells. Elife 6, pii: e22631 (2017).
-
(2017)
Elife
, vol.6
, pp. e22631
-
-
King, H.W.1
Klose, R.J.2
-
61
-
-
77952972412
-
Isolation and culture of adult mouse hepatocytes
-
Li, W. C., Ralphs, K. L. & Tosh, D. Isolation and culture of adult mouse hepatocytes. Methods Mol. Biol. 633, 185-96 (2010).
-
(2010)
Methods Mol. Biol.
, vol.633
, pp. 185-196
-
-
Li, W.C.1
Ralphs, K.L.2
Tosh, D.3
-
62
-
-
84872198346
-
Differential analysis of gene regulation at transcript resolution with RNA-seq
-
Trapnell, C. et al. Differential analysis of gene regulation at transcript resolution with RNA-seq. Nat. Biotechnol. 31, 46-53 (2013).
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 46-53
-
-
Trapnell, C.1
-
63
-
-
77952123055
-
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
-
Trapnell, C. et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat. Biotechnol. 28, 511-5 (2010).
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 511-515
-
-
Trapnell, C.1
-
64
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian, A. et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc. Natl Acad. Sci. USA 102, 15545-50 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
-
65
-
-
77958471357
-
Differential expression analysis for sequence count data
-
R106 1:CAS:528:DC%2BC3cXhsVahs7bI 20979621 3218662
-
Anders, S. & Huber, W. Differential expression analysis for sequence count data. Genome Biol. 11, R106 (2010).
-
(2010)
Genome Biol.
, vol.11
-
-
Anders, S.1
Huber, W.2
-
66
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz, S. et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38, 576-589 (2010).
-
(2010)
Mol. Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
-
67
-
-
84962921733
-
Suppression of the SWI/SNF component Arid1a promotes mammalian regeneration
-
Sun, X. et al. Suppression of the SWI/SNF component Arid1a promotes mammalian regeneration. Cell Stem Cell 18, 456-66 (2016).
-
(2016)
Cell Stem Cell
, vol.18
, pp. 456-466
-
-
Sun, X.1
-
68
-
-
84868325694
-
Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules
-
Faure, A. J. et al. Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules. Genome Res. 22, 2163-75 (2012).
-
(2012)
Genome Res.
, vol.22
, pp. 2163-2175
-
-
Faure, A.J.1
-
69
-
-
46249131371
-
Disturbed hepatic carbohydrate management during high metabolic demand in medium-chain acyl-CoA dehydrogenase (MCAD)-deficient mice
-
Herrema, H. et al. Disturbed hepatic carbohydrate management during high metabolic demand in medium-chain acyl-CoA dehydrogenase (MCAD)-deficient mice. Hepatology 47, 1894-904 (2008).
-
(2008)
Hepatology
, vol.47
, pp. 1894-1904
-
-
Herrema, H.1
-
70
-
-
84930666013
-
Integrative genomic signatures of hepatocellular carcinoma derived from nonalcoholic Fatty liver disease
-
Frades, I. et al. Integrative genomic signatures of hepatocellular carcinoma derived from nonalcoholic Fatty liver disease. PLoS ONE 10, e0124544 (2015).
-
(2015)
PLoS ONE
, vol.10
, pp. e0124544
-
-
Frades, I.1
-
71
-
-
84905492815
-
Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome
-
Meissner, E. G. et al. Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome. J. Clin. Invest. 124, 3352-63 (2014).
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 3352-3363
-
-
Meissner, E.G.1
|