Genetic Variation Determines PPARγ Function and Anti-diabetic Drug Response in Vivo

Cell

Volumn 162, Issue 1, 2015, Pages 33-44

  Soccio, Raymond E ^a,b   Chen, Eric R ^a,b   Rajapurkar, Satyajit R ^a,b   Safabakhsh, Pegah ^a,b   Marinis, Jill M ^a,b   Dispirito, Joanna R ^a,b   Emmett, Matthew J ^a,b   Briggs, Erika R ^a,b   Fang, Bin ^a,b   Everett, Logan J ^a,b   Lim, Hee Woong ^b   Won, Kyoung Jae ^b   Steger, David J ^a,b   Wu, Ying ^c   Civelek, Mete ^d   Voight, Benjamin F ^b   Lazar, Mitchell A ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ROSIGLITAZONE; ANTIDIABETIC AGENT; TRANSCRIPTION FACTOR;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG RESPONSE; GENE ACTIVATION; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC DIFFERENCE; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; QUANTITATIVE TRAIT LOCUS; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION INITIATION SITE; 129 MOUSE; ANIMAL; C57BL MOUSE; GENETICS; METABOLISM;

MUS;

ADIPOSE TISSUE; ANIMALS; GENE EXPRESSION; HUMANS; HYPOGLYCEMIC AGENTS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; POLYMORPHISM, SINGLE NUCLEOTIDE; PPAR GAMMA; TRANSCRIPTION FACTORS;

EID: 84934325147     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.06.025     Document Type: Article

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