메뉴 건너뛰기




Volumn 199, Issue 11, 2017, Pages 3721-3730

Galectin-1: A jack-of-all-trades in the resolution of acute and chronic inflammation

Author keywords

[No Author keywords available]

Indexed keywords

GALECTIN 1; GLYCAN;

EID: 85034742647     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1701172     Document Type: Review
Times cited : (150)

References (142)
  • 2
    • 84901921079 scopus 로고    scopus 로고
    • Pro-resolving lipid mediators are leads for resolution physiology
    • Serhan, C. N. 2014. Pro-resolving lipid mediators are leads for resolution physiology. Nature 510: 92–101.
    • (2014) Nature , vol.510 , pp. 92-101
    • Serhan, C.N.1
  • 3
    • 79960990849 scopus 로고    scopus 로고
    • Resolution-associated molecular patterns (RAMP): RAMParts defending immunological homeostasis?
    • Shields, A. M., G. S. Panayi, and V. M. Corrigall. 2011. Resolution-associated molecular patterns (RAMP): RAMParts defending immunological homeostasis? Clin. Exp. Immunol. 165: 292–300.
    • (2011) Clin. Exp. Immunol. , vol.165 , pp. 292-300
    • Shields, A.M.1    Panayi, G.S.2    Corrigall, V.M.3
  • 4
    • 85009152051 scopus 로고    scopus 로고
    • Galectins: Emerging regulatory checkpoints linking tumor immunity and angiogenesis
    • Méndez-Huergo, S. P., A. G. Blidner, and G. A. Rabinovich. 2017. Galectins: emerging regulatory checkpoints linking tumor immunity and angiogenesis. Curr. Opin. Immunol. 45: 8–15.
    • (2017) Curr. Opin. Immunol. , vol.45 , pp. 8-15
    • Méndez-Huergo, S.P.1    Blidner, A.G.2    Rabinovich, G.A.3
  • 5
    • 67649774331 scopus 로고    scopus 로고
    • Galectins in innate immunity: Dual functions of host soluble beta-galactoside-binding lectins as damage-associated molecular patterns (DAMPs) and as receptors for pathogen-associated molecular patterns (PAMPs)
    • Sato, S., C. St-Pierre, P. Bhaumik, and J. Nieminen. 2009. Galectins in innate immunity: dual functions of host soluble beta-galactoside-binding lectins as damage-associated molecular patterns (DAMPs) and as receptors for pathogen-associated molecular patterns (PAMPs). Immunol. Rev. 230: 172–187.
    • (2009) Immunol. Rev. , vol.230 , pp. 172-187
    • Sato, S.1    St-Pierre, C.2    Bhaumik, P.3    Nieminen, J.4
  • 9
    • 0038701886 scopus 로고    scopus 로고
    • The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes
    • Nickel, W. 2003. The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes. Eur. J. Biochem. 270: 2109–2119.
    • (2003) Eur. J. Biochem. , vol.270 , pp. 2109-2119
    • Nickel, W.1
  • 10
    • 0028986607 scopus 로고
    • Galectin-1, a beta-galactoside-binding lectin in Chinese hamster ovary cells. II. Localization and biosynthesis
    • Cho, M., and R. D. Cummings. 1995. Galectin-1, a beta-galactoside-binding lectin in Chinese hamster ovary cells. II. Localization and biosynthesis. J. Biol. Chem. 270: 5207–5212.
    • (1995) J. Biol. Chem. , vol.270 , pp. 5207-5212
    • Cho, M.1    Cummings, R.D.2
  • 11
    • 84969900633 scopus 로고    scopus 로고
    • Galectins and immune responses-Just how do they do those things they do?
    • Thiemann, S., and L. G. Baum. 2016. Galectins and immune responses-Just how do they do those things they do? Annu. Rev. Immunol. 34: 243–264.
    • (2016) Annu. Rev. Immunol. , vol.34 , pp. 243-264
    • Thiemann, S.1    Baum, L.G.2
  • 12
    • 0033870111 scopus 로고    scopus 로고
    • Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses
    • Hsu, D. K., R. Y. Yang, Z. Pan, L. Yu, D. R. Salomon, W. P. Fung-Leung, and F. T. Liu. 2000. Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses. Am. J. Pathol. 156: 1073–1083.
    • (2000) Am. J. Pathol. , vol.156 , pp. 1073-1083
    • Hsu, D.K.1    Yang, R.Y.2    Pan, Z.3    Yu, L.4    Salomon, D.R.5    Fung-Leung, W.P.6    Liu, F.T.7
  • 14
    • 85010987773 scopus 로고    scopus 로고
    • Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration
    • Yip, P. K., A. Carrillo-Jimenez, P. King, A. Vilalta, K. Nomura, C. C. Chau, A. M. Egerton, Z. H. Liu, A. J. Shetty, J. L. Tremoleda, et al. 2017. Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration. Sci. Rep. 7: 41689.
    • (2017) Sci. Rep. , vol.7 , pp. 41689
    • Yip, P.K.1    Carrillo-Jimenez, A.2    King, P.3    Vilalta, A.4    Nomura, K.5    Chau, C.C.6    Egerton, A.M.7    Liu, Z.H.8    Shetty, A.J.9    Tremoleda, J.L.10
  • 15
    • 84962221817 scopus 로고    scopus 로고
    • Galectin-3 shapes antitumor immune responses by suppressing CD8+ T cells via LAG-3 and inhibiting expansion of plasmacytoid dendritic cells
    • Kouo, T., L. Huang, A. B. Pucsek, M. Cao, S. Solt, T. Armstrong, and E. Jaffee. 2015. Galectin-3 shapes antitumor immune responses by suppressing CD8+ T cells via LAG-3 and inhibiting expansion of plasmacytoid dendritic cells. Cancer Immunol. Res. 3: 412–423.
    • (2015) Cancer Immunol. Res. , vol.3 , pp. 412-423
    • Kouo, T.1    Huang, L.2    Pucsek, A.B.3    Cao, M.4    Solt, S.5    Armstrong, T.6    Jaffee, E.7
  • 22
    • 9444291851 scopus 로고    scopus 로고
    • Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase
    • Fuertes, M. B., L. L. Molinero, M. A. Toscano, J. M. Ilarregui, N. Rubinstein, L. Fainboim, N. W. Zwirner, and G. A. Rabinovich. 2004. Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase. Mol. Cell. Biochem. 267: 177–185.
    • (2004) Mol. Cell. Biochem. , vol.267 , pp. 177-185
    • Fuertes, M.B.1    Molinero, L.L.2    Toscano, M.A.3    Ilarregui, J.M.4    Rubinstein, N.5    Fainboim, L.6    Zwirner, N.W.7    Rabinovich, G.A.8
  • 23
    • 0034974155 scopus 로고    scopus 로고
    • Regulated expression of galectin-1 during B-cell activation and implications for T-cell apoptosis
    • Zuñiga, E., G. A. Rabinovich, M. M. Iglesias, and A. Gruppi. 2001. Regulated expression of galectin-1 during B-cell activation and implications for T-cell apoptosis. J. Leukoc. Biol. 70: 73–79.
    • (2001) J. Leukoc. Biol. , vol.70 , pp. 73-79
    • Zuñiga, E.1    Rabinovich, G.A.2    Iglesias, M.M.3    Gruppi, A.4
  • 24
    • 0029944559 scopus 로고    scopus 로고
    • Regulated expression of a 16-kd galectin-like protein in activated rat macrophages
    • Rabinovich, G., L. Castagna, C. Landa, C. M. Riera, and C. Sotomayor. 1996. Regulated expression of a 16-kd galectin-like protein in activated rat macrophages. J. Leukoc. Biol. 59: 363–370.
    • (1996) J. Leukoc. Biol. , vol.59 , pp. 363-370
    • Rabinovich, G.1    Castagna, L.2    Landa, C.3    Riera, C.M.4    Sotomayor, C.5
  • 27
    • 69049116053 scopus 로고    scopus 로고
    • Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10
    • Ilarregui, J. M., D. O. Croci, G. A. Bianco, M. A. Toscano, M. Salatino, M. E. Vermeulen, J. R. Geffner, and G. A. Rabinovich. 2009. Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10. Nat. Immunol. 10: 981–991.
    • (2009) Nat. Immunol. , vol.10 , pp. 981-991
    • Ilarregui, J.M.1    Croci, D.O.2    Bianco, G.A.3    Toscano, M.A.4    Salatino, M.5    Vermeulen, M.E.6    Geffner, J.R.7    Rabinovich, G.A.8
  • 33
    • 0037230314 scopus 로고    scopus 로고
    • Regulated expression and ultrastructural localization of galectin-1, a pro-apoptotic beta-galactoside-binding lectin, during spermatogenesis in rat testis
    • Dettin, L., N. Rubinstein, A. Aoki, G. A. Rabinovich, and C. A. Maldonado. 2003. Regulated expression and ultrastructural localization of galectin-1, a pro-apoptotic beta-galactoside-binding lectin, during spermatogenesis in rat testis. Biol. Reprod. 68: 51–59.
    • (2003) Biol. Reprod. , vol.68 , pp. 51-59
    • Dettin, L.1    Rubinstein, N.2    Aoki, A.3    Rabinovich, G.A.4    Maldonado, C.A.5
  • 34
    • 84938369571 scopus 로고    scopus 로고
    • Dual roles of endogenous and exogenous galectin-1 in the control of testicular immunopathology
    • Pérez, C. V., L. G. Gómez, G. S. Gualdoni, L. Lustig, G. A. Rabinovich, and V. A. Guazzone. 2015. Dual roles of endogenous and exogenous galectin-1 in the control of testicular immunopathology. Sci. Rep. 5: 12259.
    • (2015) Sci. Rep. , vol.5 , pp. 12259
    • Pérez, C.V.1    Gómez, L.G.2    Gualdoni, G.S.3    Lustig, L.4    Rabinovich, G.A.5    Guazzone, V.A.6
  • 36
    • 84879122077 scopus 로고    scopus 로고
    • Galectin-1–mediated suppression of Pseudomonas aeruginosa–induced corneal immunopathology
    • Suryawanshi, A., Z. Cao, T. Thitiprasert, T. S. Zaidi, and N. Panjwani. 2013. Galectin-1–mediated suppression of Pseudomonas aeruginosa–induced corneal immunopathology. J. Immunol. 190: 6397–6409.
    • (2013) J. Immunol. , vol.190 , pp. 6397-6409
    • Suryawanshi, A.1    Cao, Z.2    Thitiprasert, T.3    Zaidi, T.S.4    Panjwani, N.5
  • 42
  • 48
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • Medzhitov, R. 2008. Origin and physiological roles of inflammation. Nature 454: 428–435.
    • (2008) Nature , vol.454 , pp. 428-435
    • Medzhitov, R.1
  • 49
    • 77950365906 scopus 로고    scopus 로고
    • Nonresolving inflammation
    • Nathan, C., and A. Ding. 2010. Nonresolving inflammation. Cell 140: 871–882.
    • (2010) Cell , vol.140 , pp. 871-882
    • Nathan, C.1    Ding, A.2
  • 51
    • 0141648409 scopus 로고    scopus 로고
    • A novel biological activity for galectin-1: Inhibition of leukocyte-endothelial cell interactions in experimental inflammation
    • La, M., T. V. Cao, G. Cerchiaro, K. Chilton, J. Hirabayashi, K. Kasai, S. M. Oliani, Y. Chernajovsky, and M. Perretti. 2003. A novel biological activity for galectin-1: inhibition of leukocyte-endothelial cell interactions in experimental inflammation. Am. J. Pathol. 163: 1505–1515.
    • (2003) Am. J. Pathol. , vol.163 , pp. 1505-1515
    • La, M.1    Cao, T.V.2    Cerchiaro, G.3    Chilton, K.4    Hirabayashi, J.5    Kasai, K.6    Oliani, S.M.7    Chernajovsky, Y.8    Perretti, M.9
  • 52
    • 45949102754 scopus 로고    scopus 로고
    • Novel insights into the inhibitory effects of galectin-1 on neutrophil recruitment under flow
    • Cooper, D., L. V. Norling, and M. Perretti. 2008. Novel insights into the inhibitory effects of galectin-1 on neutrophil recruitment under flow. J. Leukoc. Biol. 83: 1459–1466.
    • (2008) J. Leukoc. Biol. , vol.83 , pp. 1459-1466
    • Cooper, D.1    Norling, L.V.2    Perretti, M.3
  • 56
    • 0037320747 scopus 로고    scopus 로고
    • Opposite effects of galectin-1 on alternative metabolic pathways of L-arginine in resident, inflammatory, and activated macrophages
    • Correa, S. G., C. E. Sotomayor, M. P. Aoki, C. A. Maldonado, and G. A. Rabinovich. 2003. Opposite effects of galectin-1 on alternative metabolic pathways of L-arginine in resident, inflammatory, and activated macrophages. Glycobiology 13: 119–128.
    • (2003) Glycobiology , vol.13 , pp. 119-128
    • Correa, S.G.1    Sotomayor, C.E.2    Aoki, M.P.3    Maldonado, C.A.4    Rabinovich, G.A.5
  • 57
    • 0034778551 scopus 로고    scopus 로고
    • Regulated expression and effect of galectin-1 on Trypanosoma cruzi–infected macrophages: Modulation of microbicidal activity and survival
    • Zúñiga, E., A. Gruppi, J. Hirabayashi, K. I. Kasai, and G. A. Rabinovich. 2001. Regulated expression and effect of galectin-1 on Trypanosoma cruzi–infected macrophages: modulation of microbicidal activity and survival. Infect. Immun. 69: 6804–6812.
    • (2001) Infect. Immun. , vol.69 , pp. 6804-6812
    • Zúñiga, E.1    Gruppi, A.2    Hirabayashi, J.3    Kasai, K.I.4    Rabinovich, G.A.5
  • 58
    • 33845958124 scopus 로고    scopus 로고
    • A novel function for galectin-1 at the crossroad of innate and adaptive immunity: Galectin-1 regulates monocyte/macrophage physiology through a nonapoptotic ERK-dependent pathway
    • Barrionuevo, P., M. Beigier-Bompadre, J. M. Ilarregui, M. A. Toscano, G. A. Bianco, M. A. Isturiz, and G. A. Rabinovich. 2007. A novel function for galectin-1 at the crossroad of innate and adaptive immunity: galectin-1 regulates monocyte/macrophage physiology through a nonapoptotic ERK-dependent pathway. J. Immunol. 178: 436–445.
    • (2007) J. Immunol. , vol.178 , pp. 436-445
    • Barrionuevo, P.1    Beigier-Bompadre, M.2    Ilarregui, J.M.3    Toscano, M.A.4    Bianco, G.A.5    Isturiz, M.A.6    Rabinovich, G.A.7
  • 59
    • 84889101128 scopus 로고    scopus 로고
    • Galectin-1 induces 12/15-lipoxygenase expression in murine macrophages and favors their conversion toward a pro-resolving phenotype
    • Rostoker, R., H. Yaseen, S. Schif-Zuck, R. G. Lichtenstein, G. A. Rabinovich, and A. Ariel. 2013. Galectin-1 induces 12/15-lipoxygenase expression in murine macrophages and favors their conversion toward a pro-resolving phenotype. Prostaglandins Other Lipid Mediat. 107: 85–94.
    • (2013) Prostaglandins Other Lipid Mediat , vol.107 , pp. 85-94
    • Rostoker, R.1    Yaseen, H.2    Schif-Zuck, S.3    Lichtenstein, R.G.4    Rabinovich, G.A.5    Ariel, A.6
  • 60
    • 71049158682 scopus 로고    scopus 로고
    • Galectin-1 stimulates monocyte chemotaxis via the p44/42 MAP kinase pathway and a pertussis toxin-sensitive pathway
    • Malik, R. K., R. R. Ghurye, D. J. Lawrence-Watt, and H. J. Stewart. 2009. Galectin-1 stimulates monocyte chemotaxis via the p44/42 MAP kinase pathway and a pertussis toxin-sensitive pathway. Glycobiology 19: 1402–1407.
    • (2009) Glycobiology , vol.19 , pp. 1402-1407
    • Malik, R.K.1    Ghurye, R.R.2    Lawrence-Watt, D.J.3    Stewart, H.J.4
  • 61
    • 33745301484 scopus 로고    scopus 로고
    • Galectin-1–matured human monocyte-derived dendritic cells have enhanced migration through extracellular matrix
    • Fulcher, J. A., S. T. Hashimi, E. L. Levroney, M. Pang, K. B. Gurney, L. G. Baum, and B. Lee. 2006. Galectin-1–matured human monocyte-derived dendritic cells have enhanced migration through extracellular matrix. J. Immunol. 177: 216–226.
    • (2006) J. Immunol. , vol.177 , pp. 216-226
    • Fulcher, J.A.1    Hashimi, S.T.2    Levroney, E.L.3    Pang, M.4    Gurney, K.B.5    Baum, L.G.6    Lee, B.7
  • 62
  • 63
    • 84941585321 scopus 로고    scopus 로고
    • Galectin-1 regulates tissue exit of specific dendritic cell populations
    • Thiemann, S., J. H. Man, M. H. Chang, B. Lee, and L. G. Baum. 2015. Galectin-1 regulates tissue exit of specific dendritic cell populations. J. Biol. Chem. 290: 22662–22677.
    • (2015) J. Biol. Chem. , vol.290 , pp. 22662-22677
    • Thiemann, S.1    Man, J.H.2    Chang, M.H.3    Lee, B.4    Baum, L.G.5
  • 64
    • 67649794885 scopus 로고    scopus 로고
    • Conveying glycan information into T-cell homeostatic programs: A challenging role for galectin-1 in inflammatory and tumor microenvironments
    • Rabinovich, G. A., and J. M. Ilarregui. 2009. Conveying glycan information into T-cell homeostatic programs: a challenging role for galectin-1 in inflammatory and tumor microenvironments. Immunol. Rev. 230: 144–159.
    • (2009) Immunol. Rev. , vol.230 , pp. 144-159
    • Rabinovich, G.A.1    Ilarregui, J.M.2
  • 65
    • 30744445427 scopus 로고    scopus 로고
    • Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death
    • Stillman, B. N., D. K. Hsu, M. Pang, C. F. Brewer, P. Johnson, F. T. Liu, and L. G. Baum. 2006. Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death. J. Immunol. 176: 778–789.
    • (2006) J. Immunol. , vol.176 , pp. 778-789
    • Stillman, B.N.1    Hsu, D.K.2    Pang, M.3    Brewer, C.F.4    Johnson, P.5    Liu, F.T.6    Baum, L.G.7
  • 66
    • 14844334137 scopus 로고    scopus 로고
    • Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpo-larization, budding, and fission
    • Matarrese, P., A. Tinari, E. Mormone, G. A. Bianco, M. A. Toscano, B. Ascione, G. A. Rabinovich, and W. Malorni. 2005. Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpo-larization, budding, and fission. J. Biol. Chem. 280: 6969–6985.
    • (2005) J. Biol. Chem. , vol.280 , pp. 6969-6985
    • Matarrese, P.1    Tinari, A.2    Mormone, E.3    Bianco, G.A.4    Toscano, M.A.5    Ascione, B.6    Rabinovich, G.A.7    Malorni, W.8
  • 68
    • 33845976972 scopus 로고    scopus 로고
    • Human galectin-1, -2, and -4 induce surface exposure of phosphatidylserine in activated human neutrophils but not in activated T cells
    • Stowell, S. R., S. Karmakar, C. J. Stowell, M. Dias-Baruffi, R. P. McEver, and R. D. Cummings. 2007. Human galectin-1, -2, and -4 induce surface exposure of phosphatidylserine in activated human neutrophils but not in activated T cells. Blood 109: 219–227.
    • (2007) Blood , vol.109 , pp. 219-227
    • Stowell, S.R.1    Karmakar, S.2    Stowell, C.J.3    Dias-Baruffi, M.4    McEver, R.P.5    Cummings, R.D.6
  • 69
  • 72
    • 66949166399 scopus 로고    scopus 로고
    • Galectin-1 tunes TCR binding and signal transduction to regulate CD8 burst size
    • Liu, S. D., T. Tomassian, K. W. Bruhn, J. F. Miller, F. Poirier, and M. C. Miceli. 2009. Galectin-1 tunes TCR binding and signal transduction to regulate CD8 burst size. J. Immunol. 182: 5283–5295.
    • (2009) J. Immunol. , vol.182 , pp. 5283-5295
    • Liu, S.D.1    Tomassian, T.2    Bruhn, K.W.3    Miller, J.F.4    Poirier, F.5    Miceli, M.C.6
  • 75
    • 84858790272 scopus 로고    scopus 로고
    • Galectin-1 triggers an immunoregulatory signature in Th cells functionally defined by IL-10 expression
    • Cedeno-Laurent, F., M. Opperman, S. R. Barthel, V. K. Kuchroo, and C. J. Dimitroff. 2012. Galectin-1 triggers an immunoregulatory signature in Th cells functionally defined by IL-10 expression. J. Immunol. 188: 3127–3137.
    • (2012) J. Immunol. , vol.188 , pp. 3127-3137
    • Cedeno-Laurent, F.1    Opperman, M.2    Barthel, S.R.3    Kuchroo, V.K.4    Dimitroff, C.J.5
  • 77
    • 64249146003 scopus 로고    scopus 로고
    • Cross-linking of GM1 ganglioside by galectin-1 mediates regulatory T cell activity involving TRPC5 channel activation: Possible role in suppressing experimental autoimmune encephalomyelitis
    • Wang, J., Z. H. Lu, H. J. Gabius, C. Rohowsky-Kochan, R. W. Ledeen, and G. Wu. 2009. Cross-linking of GM1 ganglioside by galectin-1 mediates regulatory T cell activity involving TRPC5 channel activation: possible role in suppressing experimental autoimmune encephalomyelitis. J. Immunol. 182: 4036–4045.
    • (2009) J. Immunol. , vol.182 , pp. 4036-4045
    • Wang, J.1    Lu, Z.H.2    Gabius, H.J.3    Rohowsky-Kochan, C.4    Ledeen, R.W.5    Wu, G.6
  • 78
    • 0036790940 scopus 로고    scopus 로고
    • Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering
    • Gauthier, L., B. Rossi, F. Roux, E. Termine, and C. Schiff. 2002. Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in synapse formation between pre-B and stromal cells and in pre-BCR triggering. Proc. Natl. Acad. Sci. USA 99: 13014–13019.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13014-13019
    • Gauthier, L.1    Rossi, B.2    Roux, F.3    Termine, E.4    Schiff, C.5
  • 79
    • 67651102911 scopus 로고    scopus 로고
    • Impaired B-cell development at the pre-BII-cell stage in galectin-1–deficient mice due to inefficient pre-BII/stromal cell interactions
    • Espeli, M., S. J. Mancini, C. Breton, F. Poirier, and C. Schiff. 2009. Impaired B-cell development at the pre-BII-cell stage in galectin-1–deficient mice due to inefficient pre-BII/stromal cell interactions. Blood 113: 5878–5886.
    • (2009) Blood , vol.113 , pp. 5878-5886
    • Espeli, M.1    Mancini, S.J.2    Breton, C.3    Poirier, F.4    Schiff, C.5
  • 83
    • 63149096258 scopus 로고    scopus 로고
    • T cell leukemia/ lymphoma 1 and galectin-1 regulate survival/cell death pathways in human naive and IgM+ memory B cells through altering balances in Bcl-2 family proteins
    • Tabrizi, S. J., H. Niiro, M. Masui, G. Yoshimoto, T. Iino, Y. Kikushige, T. Wakasaki, E. Baba, S. Shimoda, T. Miyamoto, et al. 2009. T cell leukemia/ lymphoma 1 and galectin-1 regulate survival/cell death pathways in human naive and IgM+ memory B cells through altering balances in Bcl-2 family proteins. J. Immunol. 182: 1490–1499.
    • (2009) J. Immunol. , vol.182 , pp. 1490-1499
    • Tabrizi, S.J.1    Niiro, H.2    Masui, M.3    Yoshimoto, G.4    Iino, T.5    Kikushige, Y.6    Wakasaki, T.7    Baba, E.8    Shimoda, S.9    Miyamoto, T.10
  • 84
    • 84878029193 scopus 로고    scopus 로고
    • Galectin 1 modulates plasma cell homeostasis and regulates the humoral immune response
    • Anginot, A., M. Espeli, L. Chasson, S. J. Mancini, and C. Schiff. 2013. Galectin 1 modulates plasma cell homeostasis and regulates the humoral immune response. J. Immunol. 190: 5526–5533.
    • (2013) J. Immunol. , vol.190 , pp. 5526-5533
    • Anginot, A.1    Espeli, M.2    Chasson, L.3    Mancini, S.J.4    Schiff, C.5
  • 86
    • 0025309457 scopus 로고
    • Recombinant human beta-galactoside binding lectin suppresses clinical and histological signs of experimental autoimmune encephalomyelitis
    • Offner, H., B. Celnik, T. S. Bringman, D. Casentini-Borocz, G. E. Nedwin, and A. A. Vandenbark. 1990. Recombinant human beta-galactoside binding lectin suppresses clinical and histological signs of experimental autoimmune encephalomyelitis. J. Neuroimmunol. 28: 177–184.
    • (1990) J. Neuroimmunol. , vol.28 , pp. 177-184
    • Offner, H.1    Celnik, B.2    Bringman, T.S.3    Casentini-Borocz, D.4    Nedwin, G.E.5    Vandenbark, A.A.6
  • 88
    • 84986548155 scopus 로고    scopus 로고
    • Galectin-1 circumvents lysolecithin-induced demyelination through the modulation of microglial polarization/ phagocytosis and oligodendroglial differentiation
    • Rinaldi, M., L. Thomas, P. Mathieu, P. Carabias, M. F. Troncoso, J. M. Pasquini, G. A. Rabinovich, and L. A. Pasquini. 2016. Galectin-1 circumvents lysolecithin-induced demyelination through the modulation of microglial polarization/ phagocytosis and oligodendroglial differentiation. Neurobiol. Dis. 96: 127–143.
    • (2016) Neurobiol. Dis. , vol.96 , pp. 127-143
    • Rinaldi, M.1    Thomas, L.2    Mathieu, P.3    Carabias, P.4    Troncoso, M.F.5    Pasquini, J.M.6    Rabinovich, G.A.7    Pasquini, L.A.8
  • 89
    • 85007507220 scopus 로고    scopus 로고
    • Galectin-1 reduces neuroinflammation via modulation of nitric oxide-arginase signaling in HIV-1–transfected microglia: A gold nano-particle–galectin-1 “Nanoplex” a possible neurotherapeutic?
    • Aalinkeel, R., C. S. Mangum, E. Abou-Jaoude, J. L. Reynolds, M. Liu, K. Sundquist, N. U. Parikh, L. D. Chaves, M. J. Mammen, S. A. Schwartz, and S. D. Mahajan. 2017. Galectin-1 reduces neuroinflammation via modulation of nitric oxide-arginase signaling in HIV-1–transfected microglia: a gold nano-particle–galectin-1 “Nanoplex” a possible neurotherapeutic? J. Neuroimmune Pharmacol. 12: 133–151.
    • (2017) J. Neuroimmune Pharmacol. , vol.12 , pp. 133-151
    • Aalinkeel, R.1    Mangum, C.S.2    Abou-Jaoude, E.3    Reynolds, J.L.4    Liu, M.5    Sundquist, K.6    Parikh, N.U.7    Chaves, L.D.8    Mammen, M.J.9    Schwartz, S.A.10    Mahajan, S.D.11
  • 90
    • 0032525046 scopus 로고    scopus 로고
    • Activated rat macrophages produce a galectin-1–like protein that induces apoptosis of T cells: Biochemical and functional characterization
    • Rabinovich, G. A., M. M. Iglesias, N. M. Modesti, L. F. Castagna, C. Wolfenstein-Todel, C. M. Riera, and C. E. Sotomayor. 1998. Activated rat macrophages produce a galectin-1–like protein that induces apoptosis of T cells: biochemical and functional characterization. J. Immunol. 160: 4831–4840.
    • (1998) J. Immunol. , vol.160 , pp. 4831-4840
    • Rabinovich, G.A.1    Iglesias, M.M.2    Modesti, N.M.3    Castagna, L.F.4    Wolfenstein-Todel, C.5    Riera, C.M.6    Sotomayor, C.E.7
  • 91
    • 0001853244 scopus 로고    scopus 로고
    • Specific inhibition of T-cell adhesion to extracellular matrix and proinflammatory cytokine secretion by human recombinant galectin-1
    • Rabinovich, G. A., A. Ariel, R. Hershkoviz, J. Hirabayashi, K. I. Kasai, and O. Lider. 1999. Specific inhibition of T-cell adhesion to extracellular matrix and proinflammatory cytokine secretion by human recombinant galectin-1. Immunology 97: 100–106.
    • (1999) Immunology , vol.97 , pp. 100-106
    • Rabinovich, G.A.1    Ariel, A.2    Hershkoviz, R.3    Hirabayashi, J.4    Kasai, K.I.5    Lider, O.6
  • 92
    • 0033517113 scopus 로고    scopus 로고
    • Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis
    • Rabinovich, G. A., G. Daly, H. Dreja, H. Tailor, C. M. Riera, J. Hirabayashi, and Y. Chernajovsky. 1999. Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis. J. Exp. Med. 190: 385–398.
    • (1999) J. Exp. Med. , vol.190 , pp. 385-398
    • Rabinovich, G.A.1    Daly, G.2    Dreja, H.3    Tailor, H.4    Riera, C.M.5    Hirabayashi, J.6    Chernajovsky, Y.7
  • 93
    • 0034897737 scopus 로고    scopus 로고
    • Expression of galectins-1 and -3 correlates with defective mononuclear cell apoptosis in patients with juvenile idiopathic arthritis
    • Harjacek, M., S. Diaz-Cano, M. De Miguel, H. Wolfe, C. A. Maldonado, and G. A. Rabinovich. 2001. Expression of galectins-1 and -3 correlates with defective mononuclear cell apoptosis in patients with juvenile idiopathic arthritis. J. Rheu-matol. 28: 1914–1922.
    • (2001) J. Rheu-Matol , vol.28 , pp. 1914-1922
    • Harjacek, M.1    Diaz-Cano, S.2    De Miguel, M.3    Wolfe, H.4    Maldonado, C.A.5    Rabinovich, G.A.6
  • 94
    • 77957979421 scopus 로고    scopus 로고
    • Intra-articular lentivirus-mediated delivery of galectin-3 shRNA and galectin-1 gene ameliorates collagen-induced arthritis
    • Wang, C. R., A. L. Shiau, S. Y. Chen, Z. S. Cheng, Y. T. Li, C. H. Lee, Y. T. Yo, C. W. Lo, Y. S. Lin, H. Y. Juan, et al. 2010. Intra-articular lentivirus-mediated delivery of galectin-3 shRNA and galectin-1 gene ameliorates collagen-induced arthritis. Gene Ther. 17: 1225–1233.
    • (2010) Gene Ther , vol.17 , pp. 1225-1233
    • Wang, C.R.1    Shiau, A.L.2    Chen, S.Y.3    Cheng, Z.S.4    Li, Y.T.5    Lee, C.H.6    Yo, Y.T.7    Lo, C.W.8    Lin, Y.S.9    Juan, H.Y.10
  • 95
    • 66449121028 scopus 로고    scopus 로고
    • Galectin 3 induces a distinctive pattern of cytokine and chemokine production in rheumatoid synovial fibroblasts via selective signaling pathways
    • Filer, A., M. Bik, G. N. Parsonage, J. Fitton, E. Trebilcock, K. Howlett, M. Cook, K. Raza, D. L. Simmons, A. M. Thomas, et al. 2009. Galectin 3 induces a distinctive pattern of cytokine and chemokine production in rheumatoid synovial fibroblasts via selective signaling pathways. Arthritis Rheum. 60: 1604–1614.
    • (2009) Arthritis Rheum , vol.60 , pp. 1604-1614
    • Filer, A.1    Bik, M.2    Parsonage, G.N.3    Fitton, J.4    Trebilcock, E.5    Howlett, K.6    Cook, M.7    Raza, K.8    Simmons, D.L.9    Thomas, A.M.10
  • 96
    • 84879617777 scopus 로고    scopus 로고
    • Endogenous galectin-1 exerts tonic inhibition on experimental arthritis
    • Iqbal, A. J., D. Cooper, A. Vugler, B. R. Gittens, A. Moore, and M. Perretti. 2013. Endogenous galectin-1 exerts tonic inhibition on experimental arthritis. J. Immunol. 191: 171–177.
    • (2013) J. Immunol. , vol.191 , pp. 171-177
    • Iqbal, A.J.1    Cooper, D.2    Vugler, A.3    Gittens, B.R.4    Moore, A.5    Perretti, M.6
  • 97
    • 84940854868 scopus 로고    scopus 로고
    • Protective effects of the galectin-1 protein on in vivo and in vitro models of ocular inflammation
    • Zanon, Cde. F., N. M. Sonehara, A. P. Girol, C. D. Gil, and S. M. Oliani. 2015. Protective effects of the galectin-1 protein on in vivo and in vitro models of ocular inflammation. Mol. Vis. 21: 1036–1050
    • (2015) Mol. Vis. , vol.21 , pp. 1036-1050
    • Zanon, C.De.F.1    Sonehara, N.M.2    Girol, A.P.3    Gil, C.D.4    Oliani, S.M.5
  • 98
    • 84860317094 scopus 로고    scopus 로고
    • Galectin-1 reduces the severity of herpes simplex virus-induced ocular immunopathological lesions
    • Rajasagi, N. K., A. Suryawanshi, S. Sehrawat, P. B. Reddy, S. Mulik, M. Hirashima, and B. T. Rouse. 2012. Galectin-1 reduces the severity of herpes simplex virus-induced ocular immunopathological lesions. J. Immunol. 188: 4631–4643.
    • (2012) J. Immunol. , vol.188 , pp. 4631-4643
    • Rajasagi, N.K.1    Suryawanshi, A.2    Sehrawat, S.3    Reddy, P.B.4    Mulik, S.5    Hirashima, M.6    Rouse, B.T.7
  • 99
    • 0032712421 scopus 로고    scopus 로고
    • Immunocytochemical study of the distribution of a 16-kDa galectin in the chicken retina
    • Maldonado, C. A., L. F. Castagna, G. A. Rabinovich, and C. A. Landa. 1999. Immunocytochemical study of the distribution of a 16-kDa galectin in the chicken retina. Invest. Ophthalmol. Vis. Sci. 40: 2971–2977
    • (1999) Invest. Ophthalmol. Vis. Sci. , vol.40 , pp. 2971-2977
    • Maldonado, C.A.1    Castagna, L.F.2    Rabinovich, G.A.3    Landa, C.A.4
  • 100
    • 0038125664 scopus 로고    scopus 로고
    • Participation of pigment epithelium in ocular immune privilege. 3. Epithelia cultured from iris, ciliary body, and retina suppress T-cell activation by partially non-overlapping mechanisms
    • Ishida, K., N. Panjwani, Z. Cao, and J. W. Streilein. 2003. Participation of pigment epithelium in ocular immune privilege. 3. Epithelia cultured from iris, ciliary body, and retina suppress T-cell activation by partially non-overlapping mechanisms. Ocul. Immunol. Inflamm. 11: 91–105.
    • (2003) Ocul. Immunol. Inflamm. , vol.11 , pp. 91-105
    • Ishida, K.1    Panjwani, N.2    Cao, Z.3    Streilein, J.W.4
  • 101
    • 33645968127 scopus 로고    scopus 로고
    • Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis
    • Romero, M. D., J. C. Muiño, G. A. Bianco, M. Ferrero, C. P. Juarez, J. D. Luna, and G. A. Rabinovich. 2006. Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis. Invest. Ophthalmol. Vis. Sci. 47: 1550–1556.
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 1550-1556
    • Romero, M.D.1    Muiño, J.C.2    Bianco, G.A.3    Ferrero, M.4    Juarez, C.P.5    Luna, J.D.6    Rabinovich, G.A.7
  • 102
    • 84973171128 scopus 로고    scopus 로고
    • Murine Sertoli cells promote the development of tolerogenic dendritic cells: A pivotal role of galectin-1
    • Gao, J., X. Wang, Y. Wang, F. Han, W. Cai, B. Zhao, Y. Li, S. Han, X. Wu, and D. Hu. 2016. Murine Sertoli cells promote the development of tolerogenic dendritic cells: a pivotal role of galectin-1. Immunology 148: 253–265.
    • (2016) Immunology , vol.148 , pp. 253-265
    • Gao, J.1    Wang, X.2    Wang, Y.3    Han, F.4    Cai, W.5    Zhao, B.6    Li, Y.7    Han, S.8    Wu, X.9    Hu, D.10
  • 105
    • 58149188480 scopus 로고    scopus 로고
    • The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells
    • Schneider, A., M. Rieck, S. Sanda, C. Pihoker, C. Greenbaum, and J. H. Buckner. 2008. The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells. J. Immunol. 181: 7350–7355.
    • (2008) J. Immunol. , vol.181 , pp. 7350-7355
    • Schneider, A.1    Rieck, M.2    Sanda, S.3    Pihoker, C.4    Greenbaum, C.5    Buckner, J.H.6
  • 106
    • 80052906797 scopus 로고    scopus 로고
    • Ganglioside GM1 deficiency in effector T cells from NOD mice induces resistance to regulatory T-cell suppression
    • Wu, G., Z. H. Lu, H. J. Gabius, R. W. Ledeen, and D. Bleich. 2011. Ganglioside GM1 deficiency in effector T cells from NOD mice induces resistance to regulatory T-cell suppression. Diabetes 60: 2341–2349.
    • (2011) Diabetes , vol.60 , pp. 2341-2349
    • Wu, G.1    Lu, Z.H.2    Gabius, H.J.3    Ledeen, R.W.4    Bleich, D.5
  • 107
    • 58149326953 scopus 로고    scopus 로고
    • Galectin-1 functions as a Th2 cytokine that selectively induces Th1 apoptosis and promotes Th2 function
    • Motran, C. C., K. M. Molinder, S. D. Liu, F. Poirier, and M. C. Miceli. 2008. Galectin-1 functions as a Th2 cytokine that selectively induces Th1 apoptosis and promotes Th2 function. Eur. J. Immunol. 38: 3015–3027.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 3015-3027
    • Motran, C.C.1    Molinder, K.M.2    Liu, S.D.3    Poirier, F.4    Miceli, M.C.5
  • 108
    • 84899639879 scopus 로고    scopus 로고
    • Cytokines in inflammatory bowel disease
    • Neurath, M. F. 2014. Cytokines in inflammatory bowel disease. Nat. Rev. Immunol. 14: 329–342.
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 329-342
    • Neurath, M.F.1
  • 109
    • 84932608065 scopus 로고    scopus 로고
    • Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease
    • Nalle, S. C., and J. R. Turner. 2015. Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease. Mucosal Immunol. 8: 720–730.
    • (2015) Mucosal Immunol. , vol.8 , pp. 720-730
    • Nalle, S.C.1    Turner, J.R.2
  • 112
    • 49949103139 scopus 로고    scopus 로고
    • Galectin-4 controls intestinal inflammation by selective regulation of peripheral and mucosal T cell apoptosis and cell cycle
    • Paclik, D., S. Danese, U. Berndt, B. Wiedenmann, A. Dignass, and A. Sturm. 2008. Galectin-4 controls intestinal inflammation by selective regulation of peripheral and mucosal T cell apoptosis and cell cycle. PLoS One 3: e2629.
    • (2008) PLoS One , vol.3
    • Paclik, D.1    Danese, S.2    Berndt, U.3    Wiedenmann, B.4    Dignass, A.5    Sturm, A.6
  • 117
    • 85010908346 scopus 로고    scopus 로고
    • Revisiting type 2-high and type 2-low airway inflammation in asthma: Current knowledge and therapeutic implications
    • Robinson, D., M. Humbert, R. Buhl, A. A. Cruz, H. Inoue, S. Korom, N. A. Hanania, and P. Nair. 2017. Revisiting type 2-high and type 2-low airway inflammation in asthma: current knowledge and therapeutic implications. Clin. Exp. Allergy 47: 161–175.
    • (2017) Clin. Exp. Allergy , vol.47 , pp. 161-175
    • Robinson, D.1    Humbert, M.2    Buhl, R.3    Cruz, A.A.4    Inoue, H.5    Korom, S.6    Hanania, N.A.7    Nair, P.8
  • 118
    • 40449120636 scopus 로고    scopus 로고
    • Inhibitory control of endothelial galectin-1 on in vitro and in vivo lymphocyte trafficking
    • Norling, L. V., A. L. Sampaio, D. Cooper, and M. Perretti. 2008. Inhibitory control of endothelial galectin-1 on in vitro and in vivo lymphocyte trafficking. FASEB J. 22: 682–690.
    • (2008) FASEB J. , vol.22 , pp. 682-690
    • Norling, L.V.1    Sampaio, A.L.2    Cooper, D.3    Perretti, M.4
  • 121
    • 33749370699 scopus 로고    scopus 로고
    • Spatial expression of two anti-inflammatory mediators, annexin 1 and galectin-1, in nasal polyposis
    • Sena, A. A., P. J. Provazzi, A. M. Fernandes, P. M. Cury, P. Rahal, and S. M. Oliani. 2006. Spatial expression of two anti-inflammatory mediators, annexin 1 and galectin-1, in nasal polyposis. Clin. Exp. Allergy 36: 1260–1267.
    • (2006) Clin. Exp. Allergy , vol.36 , pp. 1260-1267
    • Sena, A.A.1    Provazzi, P.J.2    Fernandes, A.M.3    Cury, P.M.4    Rahal, P.5    Oliani, S.M.6
  • 122
    • 85027517285 scopus 로고    scopus 로고
    • Long-term effects: Galectin-1 and specific immunotherapy for allergic responses in the intestine
    • Yang, L. T., Q. Shu, X. Q. Luo, Z. Q. Liu, S. Q. Qiu, J. Q. Liu, H. J. Guo, L. J. Li, M. G. Li, D. B. Liu, et al. 2017. Long-term effects: Galectin-1 and specific immunotherapy for allergic responses in the intestine. Allergy. DOI: 10.1111/all.13256.
    • (2017) Allergy
    • Yang, L.T.1    Shu, Q.2    Luo, X.Q.3    Liu, Z.Q.4    Qiu, S.Q.5    Liu, J.Q.6    Guo, H.J.7    Li, L.J.8    Li, M.G.9    Liu, D.B.10
  • 123
    • 84875050777 scopus 로고    scopus 로고
    • Sweetening’ pregnancy: Galectins at the fetomaternal interface
    • Blidner, A. G., and G. A. Rabinovich. 2013. ‘Sweetening’ pregnancy: galectins at the fetomaternal interface. Am. J. Reprod. Immunol. 69: 369–382.
    • (2013) Am. J. Reprod. Immunol. , vol.69 , pp. 369-382
    • Blidner, A.G.1    Rabinovich, G.A.2
  • 125
    • 57449107632 scopus 로고    scopus 로고
    • T cell apoptosis at the maternal-fetal interface in early human pregnancy, involvement of galectin-1
    • Kopcow, H. D., F. Rosetti, Y. Leung, D. S. Allan, J. L. Kutok, and J. L. Strominger. 2008. T cell apoptosis at the maternal-fetal interface in early human pregnancy, involvement of galectin-1. Proc. Natl. Acad. Sci. USA 105: 18472–18477.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 18472-18477
    • Kopcow, H.D.1    Rosetti, F.2    Leung, Y.3    Allan, D.S.4    Kutok, J.L.5    Strominger, J.L.6
  • 128
    • 33947259319 scopus 로고    scopus 로고
    • Immunosuppressive strategies that are mediated by tumor cells
    • Rabinovich, G. A., D. Gabrilovich, and E. M. Sotomayor. 2007. Immunosuppressive strategies that are mediated by tumor cells. Annu. Rev. Immunol. 25: 267–296.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 267-296
    • Rabinovich, G.A.1    Gabrilovich, D.2    Sotomayor, E.M.3
  • 132
    • 84863718828 scopus 로고    scopus 로고
    • Inhibiting galectin-1 reduces murine lung metastasis with increased CD4(+) and CD8(+) T cells and reduced cancer cell adherence
    • Ito, K., and S. J. Ralph. 2012. Inhibiting galectin-1 reduces murine lung metastasis with increased CD4(+) and CD8(+) T cells and reduced cancer cell adherence. Clin. Exp. Metastasis 29: 561–572.
    • (2012) Clin. Exp. Metastasis , vol.29 , pp. 561-572
    • Ito, K.1    Ralph, S.J.2
  • 134
    • 84973169046 scopus 로고    scopus 로고
    • Natural killer cells require monocytic Gr-1(+)/CD11b(+) myeloid cells to eradicate orthotopically engrafted glioma cells
    • Baker, G. J., P. Chockley, D. Zamler, M. G. Castro, and P. R. Lowenstein. 2016. Natural killer cells require monocytic Gr-1(+)/CD11b(+) myeloid cells to eradicate orthotopically engrafted glioma cells. OncoImmunology 5: e1163461.
    • (2016) OncoImmunology , vol.5 , pp. e1163461
    • Baker, G.J.1    Chockley, P.2    Zamler, D.3    Castro, M.G.4    Lowenstein, P.R.5
  • 135
    • 84863214425 scopus 로고    scopus 로고
    • Neuroblastoma triggers an immunoevasive program involving galectin-1-dependent modulation of T cell and dendritic cell compartments
    • Soldati, R., E. Berger, A. C. Zenclussen, G. Jorch, H. N. Lode, M. Salatino, G. A. Rabinovich, and S. Fest. 2012. Neuroblastoma triggers an immunoevasive program involving galectin-1-dependent modulation of T cell and dendritic cell compartments. Int. J. Cancer 131: 1131–1141.
    • (2012) Int. J. Cancer , vol.131 , pp. 1131-1141
    • Soldati, R.1    Berger, E.2    Zenclussen, A.C.3    Jorch, G.4    Lode, H.N.5    Salatino, M.6    Rabinovich, G.A.7    Fest, S.8
  • 136
    • 84859849194 scopus 로고    scopus 로고
    • Galectin-1 inhibits the viability, proliferation, and Th1 cytokine production of nonmalignant T cells in patients with leukemic cutaneous T-cell lymphoma
    • Cedeno-Laurent, F., R. Watanabe, J. E. Teague, T. S. Kupper, R. A. Clark, and C. J. Dimitroff. 2012. Galectin-1 inhibits the viability, proliferation, and Th1 cytokine production of nonmalignant T cells in patients with leukemic cutaneous T-cell lymphoma. Blood 119: 3534–3538.
    • (2012) Blood , vol.119 , pp. 3534-3538
    • Cedeno-Laurent, F.1    Watanabe, R.2    Teague, J.E.3    Kupper, T.S.4    Clark, R.A.5    Dimitroff, C.J.6
  • 139
    • 85014766041 scopus 로고    scopus 로고
    • Galectin-1 drives lymphoma CD20 immunotherapy resistance: Validation of a preclinical system to identify resistance mechanisms
    • Lykken, J. M., M. Horikawa, V. Minard-Colin, M. Kamata, T. Miyagaki, J. C. Poe, and T. F. Tedder. 2016. Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanisms. Blood 127: 1886–1895.
    • (2016) Blood , vol.127 , pp. 1886-1895
    • Lykken, J.M.1    Horikawa, M.2    Minard-Colin, V.3    Kamata, M.4    Miyagaki, T.5    Poe, J.C.6    Tedder, T.F.7
  • 142
    • 84973573760 scopus 로고    scopus 로고
    • Turning-off signaling by siglecs, selectins, and galectins: Chemical inhibition of glycan-dependent interactions in cancer
    • Cagnoni, A. J., J. M. Pérez Sáez, G. A. Rabinovich, and K. V. Mariño. 2016. Turning-off signaling by siglecs, selectins, and galectins: Chemical inhibition of glycan-dependent interactions in cancer. Front. Oncol. 6: 109.
    • (2016) Front. Oncol. , vol.6 , pp. 109
    • Cagnoni, A.J.1    Pérez Sáez, J.M.2    Rabinovich, G.A.3    Mariño, K.V.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.