Galectin-1 circumvents lysolecithin-induced demyelination through the modulation of microglial polarization/phagocytosis and oligodendroglial differentiation

Neurobiology of Disease

Volumn 96, Issue , 2016, Pages 127-143

  Rinaldi, M ^a   Thomas, L ^a   Mathieu, P ^a   Carabias, P ^a   Troncoso, M F ^a   Pasquini, J M ^a   Rabinovich, G A ^a,b   Pasquini, L A ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b INST DE BIOL Y MED EXPERIMENTAL   (Argentina)

Author keywords

Demyelination remyelination; Galectin 1; Lysolecithin; Microglia; Phagocytosis

Indexed keywords

GALECTIN 1; MYELIN; 2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; CNP PROTEIN, MOUSE; ENHANCED GREEN FLUORESCENT PROTEIN; GREEN FLUORESCENT PROTEIN; LYSOPHOSPHATIDYLCHOLINE; NERVE PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL POLARITY; CONTROLLED STUDY; DEMYELINATION; IN VITRO STUDY; IN VIVO STUDY; INTRACRANIAL DRUG ADMINISTRATION; MALE; MICROGLIA; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; RAT; REMYELINIZATION; ANIMAL; BRAIN; C57BL MOUSE; CELL DIFFERENTIATION; CHEMICALLY INDUCED; DEMYELINATING DISEASE; DISEASE MODEL; DRUG EFFECTS; GENETICS; METABOLISM; NEWBORN; OLIGODENDROGLIA; PATHOLOGY; TISSUE CULTURE TECHNIQUE; TRANSGENIC MOUSE; ULTRASTRUCTURE;

2',3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE; ANIMALS; ANIMALS, NEWBORN; BRAIN; CELL DIFFERENTIATION; CELL POLARITY; DEMYELINATING DISEASES; DISEASE MODELS, ANIMAL; GALECTIN 1; GREEN FLUORESCENT PROTEINS; LYSOPHOSPHATIDYLCHOLINES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; NERVE TISSUE PROTEINS; OLIGODENDROGLIA; PHAGOCYTOSIS; TISSUE CULTURE TECHNIQUES;

EID: 84986548155     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2016.09.003     Document Type: Article

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