메뉴 건너뛰기




Volumn 195, Issue 7, 2015, Pages 3311-3324

Trypanosoma cruzi infection imparts a regulatory program in dendritic cells and T cells via galectin-1-dependent mechanisms

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GALECTIN 1; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR ALPHA; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1; GAMMA INTERFERON; IDO1 PROTEIN, MOUSE; IL10 PROTEIN, MOUSE; INDOLEAMINE 2,3 DIOXYGENASE; PDCD1LG2 PROTEIN, MOUSE; PROGRAMMED DEATH 1 LIGAND 2;

EID: 84942436387     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1403019     Document Type: Article
Times cited : (57)

References (65)
  • 1
    • 77955562196 scopus 로고    scopus 로고
    • World Health Organization. 2010. Chagas disease: control and elimination. Available at: http://apps.who.int/gb/ebwha/pdf-files/WHA63/A63-17-en.pdf.
    • (2010) Chagas Disease: Control and Elimination
  • 3
    • 0031615613 scopus 로고    scopus 로고
    • Cytokines in innate and acquired immunity to Trypanosoma cruzi infection
    • Abrahamsohn, I. A. 1998. Cytokines in innate and acquired immunity to Trypanosoma cruzi infection. Braz. J. Med. Biol. Res. 31: 117-121.
    • (1998) Braz. J. Med. Biol. Res. , vol.31 , pp. 117-121
    • Abrahamsohn, I.A.1
  • 5
    • 0030051238 scopus 로고    scopus 로고
    • Trypanosoma cruzi infection in MHC-deficient mice: Further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease
    • Tarleton, R. L., M. J. Grusby, M. Postan, and L. H. Glimcher. 1996. Trypanosoma cruzi infection in MHC-deficient mice: further evidence for the role of both class I- and class II-restricted T cells in immune resistance and disease. Int. Immunol. 8: 13-22.
    • (1996) Int. Immunol. , vol.8 , pp. 13-22
    • Tarleton, R.L.1    Grusby, M.J.2    Postan, M.3    Glimcher, L.H.4
  • 7
    • 77956209421 scopus 로고    scopus 로고
    • CD8+ T cells specific for immunodominant trans-sialidase epitopes contribute to control of Trypanosoma cruzi infection but are not required for resistance
    • Rosenberg, C. S., D. L. Martin, and R. L. Tarleton. 2010. CD8+ T cells specific for immunodominant trans-sialidase epitopes contribute to control of Trypanosoma cruzi infection but are not required for resistance. J. Immunol. 185: 560-568.
    • (2010) J. Immunol. , vol.185 , pp. 560-568
    • Rosenberg, C.S.1    Martin, D.L.2    Tarleton, R.L.3
  • 8
    • 0036605949 scopus 로고    scopus 로고
    • Chemokines, inflammation and Trypanosoma cruzi infection
    • Teixeira, M. M., R. T. Gazzinelli, and J. S. Silva. 2002. Chemokines, inflammation and Trypanosoma cruzi infection. Trends Parasitol. 18: 262-265.
    • (2002) Trends Parasitol. , vol.18 , pp. 262-265
    • Teixeira, M.M.1    Gazzinelli, R.T.2    Silva, J.S.3
  • 9
    • 79951471956 scopus 로고    scopus 로고
    • Evasion of immune responses by Trypanosoma cruzi, the etiological agent of Chagas disease
    • DosReis, G. A. 2011. Evasion of immune responses by Trypanosoma cruzi, the etiological agent of Chagas disease. Braz. J. Med. Biol. Res. 44: 84-90.
    • (2011) Braz. J. Med. Biol. Res. , vol.44 , pp. 84-90
    • DosReis, G.A.1
  • 10
    • 0036797824 scopus 로고    scopus 로고
    • Trypanosoma cruzi down-regulates lipopolysaccharide-induced MHC class i on human dendritic cells and impairs antigen presentation to specific CD8+ T lymphocytes
    • Van Overtvelt, L., M. Andrieu, V. Verhasselt, F. Connan, J. Choppin, V. Vercruysse, M. Goldman, A. Hosmalin, and B. Vray. 2002. Trypanosoma cruzi down-regulates lipopolysaccharide-induced MHC class I on human dendritic cells and impairs antigen presentation to specific CD8+ T lymphocytes. Int. Immunol. 14: 1135-1144.
    • (2002) Int. Immunol. , vol.14 , pp. 1135-1144
    • Van Overtvelt, L.1    Andrieu, M.2    Verhasselt, V.3    Connan, F.4    Choppin, J.5    Vercruysse, V.6    Goldman, M.7    Hosmalin, A.8    Vray, B.9
  • 11
    • 0037234946 scopus 로고    scopus 로고
    • Differential CD86 and CD40 co-stimulatory molecules and cytokine expression pattern induced by Trypanosoma cruzi in APCs from resistant or susceptible mice
    • Planelles, L., M. C. Thomas, C. Marañón, M. Morell, and M. C. López. 2003. Differential CD86 and CD40 co-stimulatory molecules and cytokine expression pattern induced by Trypanosoma cruzi in APCs from resistant or susceptible mice. Clin. Exp. Immunol. 131: 41-47.
    • (2003) Clin. Exp. Immunol. , vol.131 , pp. 41-47
    • Planelles, L.1    Thomas, M.C.2    Marañón, C.3    Morell, M.4    López, M.C.5
  • 12
    • 0037369744 scopus 로고    scopus 로고
    • Trypanosoma cruzi infection modulates in vivo expression of major histocompatibility complex class II molecules on antigen-presenting cells and T-cell stimulatory activity of dendritic cells in a strain-dependent manner
    • Alba Soto, C. D., G. A. Mirkin, M. E. Solana, and S. M. González Cappa. 2003. Trypanosoma cruzi infection modulates in vivo expression of major histocompatibility complex class II molecules on antigen-presenting cells and T-cell stimulatory activity of dendritic cells in a strain-dependent manner. Infect. Immun. 71: 1194-1199.
    • (2003) Infect. Immun. , vol.71 , pp. 1194-1199
    • Alba Soto, C.D.1    Mirkin, G.A.2    Solana, M.E.3    González Cappa, S.M.4
  • 14
    • 84875537655 scopus 로고    scopus 로고
    • Molecular control of steady-state dendritic cell maturation and immune homeostasis
    • Hammer, G. E., and A. Ma. 2013. Molecular control of steady-state dendritic cell maturation and immune homeostasis. Annu. Rev. Immunol. 31: 743-791.
    • (2013) Annu. Rev. Immunol. , vol.31 , pp. 743-791
    • Hammer, G.E.1    Ma, A.2
  • 15
    • 0032792516 scopus 로고    scopus 로고
    • Trypanosoma cruzi infects human dendritic cells and prevents their maturation: Inhibition of cytokines, HLA-DR, and costimulatory molecules
    • Van Overtvelt, L., N. Vanderheyde, V. Verhasselt, J. Ismaili, L. De Vos, M. Goldman, F. Willems, and B. Vray. 1999. Trypanosoma cruzi infects human dendritic cells and prevents their maturation: inhibition of cytokines, HLA-DR, and costimulatory molecules. Infect. Immun. 67: 4033-4040.
    • (1999) Infect. Immun. , vol.67 , pp. 4033-4040
    • Van Overtvelt, L.1    Vanderheyde, N.2    Verhasselt, V.3    Ismaili, J.4    De Vos, L.5    Goldman, M.6    Willems, F.7    Vray, B.8
  • 17
    • 77953616184 scopus 로고    scopus 로고
    • Central role of extracellular signal-regulated kinase and Toll-like receptor 4 in IL-10 production in regulatory dendritic cells induced by Trypanosoma cruzi
    • Poncini, C. V., G. Giménez, C. A. Pontillo, C. D. Alba-Soto, E. L. de Isola, I. Piazzón, and S. M. Cappa. 2010. Central role of extracellular signal-regulated kinase and Toll-like receptor 4 in IL-10 production in regulatory dendritic cells induced by Trypanosoma cruzi. Mol. Immunol. 47: 1981-1988.
    • (2010) Mol. Immunol. , vol.47 , pp. 1981-1988
    • Poncini, C.V.1    Giménez, G.2    Pontillo, C.A.3    Alba-Soto, C.D.4    De Isola, E.L.5    Piazzón, I.6    Cappa, S.M.7
  • 18
    • 44049095632 scopus 로고    scopus 로고
    • Protein-glycan interactions in the control of innate and adaptive immune responses
    • van Kooyk, Y., and G. A. Rabinovich. 2008. Protein-glycan interactions in the control of innate and adaptive immune responses. Nat. Immunol. 9: 593-601.
    • (2008) Nat. Immunol. , vol.9 , pp. 593-601
    • Van Kooyk, Y.1    Rabinovich, G.A.2
  • 19
    • 67349258025 scopus 로고    scopus 로고
    • Turning "sweet" on immunity: Galectin-glycan interactions in immune tolerance and inflammation
    • Rabinovich, G. A., and M. A. Toscano. 2009. Turning "sweet" on immunity: galectin-glycan interactions in immune tolerance and inflammation. Nat. Rev. Immunol. 9: 338-352.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 338-352
    • Rabinovich, G.A.1    Toscano, M.A.2
  • 22
    • 21244502470 scopus 로고    scopus 로고
    • Novel innate immune functions for galectin-1: Galectin-1 inhibits cell fusion by Nipah virus envelope glycoproteins and augments dendritic cell secretion of proinflammatory cytokines
    • Levroney, E. L., H. C. Aguilar, J. A. Fulcher, L. Kohatsu, K. E. Pace, M. Pang, K. B. Gurney, L. G. Baum, and B. Lee. 2005. Novel innate immune functions for galectin-1: galectin-1 inhibits cell fusion by Nipah virus envelope glycoproteins and augments dendritic cell secretion of proinflammatory cytokines. J. Immunol. 175: 413-420.
    • (2005) J. Immunol. , vol.175 , pp. 413-420
    • Levroney, E.L.1    Aguilar, H.C.2    Fulcher, J.A.3    Kohatsu, L.4    Pace, K.E.5    Pang, M.6    Gurney, K.B.7    Baum, L.G.8    Lee, B.9
  • 23
    • 15444380346 scopus 로고    scopus 로고
    • Galectin-1 acts as a soluble host factor that promotes HIV-1 infectivity through stabilization of virus attachment to host cells
    • Ouellet, M., S. Mercier, I. Pelletier, S. Bounou, J. Roy, J. Hirabayashi, S. Sato, and M. J. Tremblay. 2005. Galectin-1 acts as a soluble host factor that promotes HIV-1 infectivity through stabilization of virus attachment to host cells. J. Immunol. 174: 4120-4126.
    • (2005) J. Immunol. , vol.174 , pp. 4120-4126
    • Ouellet, M.1    Mercier, S.2    Pelletier, I.3    Bounou, S.4    Roy, J.5    Hirabayashi, J.6    Sato, S.7    Tremblay, M.J.8
  • 24
    • 84858766894 scopus 로고    scopus 로고
    • Regulatory circuits mediated by lectin-glycan interactions in autoimmunity and cancer
    • Rabinovich, G. A., and D. O. Croci. 2012. Regulatory circuits mediated by lectin-glycan interactions in autoimmunity and cancer. Immunity 36: 322-335.
    • (2012) Immunity , vol.36 , pp. 322-335
    • Rabinovich, G.A.1    Croci, D.O.2
  • 25
    • 69049116053 scopus 로고    scopus 로고
    • Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10
    • Ilarregui, J. M., D. O. Croci, G. A. Bianco, M. A. Toscano, M. Salatino, M. E. Vermeulen, J. R. Geffner, and G. A. Rabinovich. 2009. Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10. Nat. Immunol. 10: 981-991.
    • (2009) Nat. Immunol. , vol.10 , pp. 981-991
    • Ilarregui, J.M.1    Croci, D.O.2    Bianco, G.A.3    Toscano, M.A.4    Salatino, M.5    Vermeulen, M.E.6    Geffner, J.R.7    Rabinovich, G.A.8
  • 26
    • 65649109738 scopus 로고    scopus 로고
    • Roles of galectins in infection
    • Vasta, G. R. 2009. Roles of galectins in infection. Nat. Rev. Microbiol. 7: 424-438.
    • (2009) Nat. Rev. Microbiol. , vol.7 , pp. 424-438
    • Vasta, G.R.1
  • 27
    • 84905647104 scopus 로고    scopus 로고
    • Microbe-host interactions are positively and negatively regulated by galectin-glycan interactions
    • Baum, L. G., O. B. Garner, K. Schaefer, and B. Lee. 2014. Microbe-host interactions are positively and negatively regulated by galectin-glycan interactions. Front. Immunol. 5: 284.
    • (2014) Front. Immunol. , vol.5 , pp. 284
    • Baum, L.G.1    Garner, O.B.2    Schaefer, K.3    Lee, B.4
  • 28
    • 0037124095 scopus 로고    scopus 로고
    • Specific recognition and cleavage of galectin-3 by Leishmania major through species-specific polygalactose epitope
    • Pelletier, I., and S. Sato. 2002. Specific recognition and cleavage of galectin-3 by Leishmania major through species-specific polygalactose epitope. J. Biol. Chem. 277: 17663-17670.
    • (2002) J. Biol. Chem. , vol.277 , pp. 17663-17670
    • Pelletier, I.1    Sato, S.2
  • 29
    • 33749125248 scopus 로고    scopus 로고
    • Galectin-3 induces death of Candida species expressing specific b-1,2-linked mannans
    • Kohatsu, L., D. K. Hsu, A. G. Jegalian, F. T. Liu, and L. G. Baum. 2006. Galectin-3 induces death of Candida species expressing specific b-1,2-linked mannans. J. Immunol. 177: 4718-4726.
    • (2006) J. Immunol. , vol.177 , pp. 4718-4726
    • Kohatsu, L.1    Hsu, D.K.2    Jegalian, A.G.3    Liu, F.T.4    Baum, L.G.5
  • 33
    • 7044228232 scopus 로고    scopus 로고
    • Human galectin-3 promotes Trypanosoma cruzi adhesion to human coronary artery smooth muscle cells
    • Kleshchenko, Y. Y., T. N. Moody, V. A. Furtak, J. Ochieng, M. F. Lima, and F. Villalta. 2004. Human galectin-3 promotes Trypanosoma cruzi adhesion to human coronary artery smooth muscle cells. Infect. Immun. 72: 6717-6721.
    • (2004) Infect. Immun. , vol.72 , pp. 6717-6721
    • Kleshchenko, Y.Y.1    Moody, T.N.2    Furtak, V.A.3    Ochieng, J.4    Lima, M.F.5    Villalta, F.6
  • 34
    • 51449101867 scopus 로고    scopus 로고
    • Galectin-1 on cervical epithelial cells is a receptor for the sexually transmitted human parasite Trichomonas vaginalis
    • Okumura, C. Y., L. G. Baum, and P. J. Johnson. 2008. Galectin-1 on cervical epithelial cells is a receptor for the sexually transmitted human parasite Trichomonas vaginalis. Cell. Microbiol. 10: 2078-2090.
    • (2008) Cell. Microbiol. , vol.10 , pp. 2078-2090
    • Okumura, C.Y.1    Baum, L.G.2    Johnson, P.J.3
  • 35
    • 0034974155 scopus 로고    scopus 로고
    • Regulated expression of galectin-1 during B-cell activation and implications for T-cell apoptosis
    • Zuñiga, E., G. A. Rabinovich, M. M. Iglesias, and A. Gruppi. 2001. Regulated expression of galectin-1 during B-cell activation and implications for T-cell apoptosis. J. Leukoc. Biol. 70: 73-79.
    • (2001) J. Leukoc. Biol. , vol.70 , pp. 73-79
    • Zuñiga, E.1    Rabinovich, G.A.2    Iglesias, M.M.3    Gruppi, A.4
  • 36
    • 0034778551 scopus 로고    scopus 로고
    • Regulated expression and effect of galectin-1 on Trypanosoma cruzi-infected macrophages: Modulation of microbicidal activity and survival
    • Zúñiga, E., A. Gruppi, J. Hirabayashi, K. I. Kasai, and G. A. Rabinovich. 2001. Regulated expression and effect of galectin-1 on Trypanosoma cruzi-infected macrophages: modulation of microbicidal activity and survival. Infect. Immun. 69: 6804-6812.
    • (2001) Infect. Immun. , vol.69 , pp. 6804-6812
    • Zúñiga, E.1    Gruppi, A.2    Hirabayashi, J.3    Kasai, K.I.4    Rabinovich, G.A.5
  • 38
    • 84898538880 scopus 로고    scopus 로고
    • DTU i isolates of Trypanosoma cruzi induce upregulation of galectin-3 in murine myocarditis and fibrosis
    • Ferrer, M. F., C. A. Pascuale, R. M. Gomez, and M. S. Leguizamón. 2014. DTU I isolates of Trypanosoma cruzi induce upregulation of galectin-3 in murine myocarditis and fibrosis. Parasitology 141: 849-858.
    • (2014) Parasitology , vol.141 , pp. 849-858
    • Ferrer, M.F.1    Pascuale, C.A.2    Gomez, R.M.3    Leguizamón, M.S.4
  • 39
    • 84942427346 scopus 로고    scopus 로고
    • Interactions of human galectins with Trypanosoma cruzi: Binding profile correlate with genetic clustering of lineages
    • Pineda, M. A., L. Corvo, M. Soto, M. Fresno, and P. Bonay. 2015. Interactions of human galectins with Trypanosoma cruzi: binding profile correlate with genetic clustering of lineages. Glycobiology 25: 197-210.
    • (2015) Glycobiology , vol.25 , pp. 197-210
    • Pineda, M.A.1    Corvo, L.2    Soto, M.3    Fresno, M.4    Bonay, P.5
  • 42
    • 67651171608 scopus 로고    scopus 로고
    • Reduction of parasite levels in blood improves pregnancy outcome during experimental Trypanosoma cruzi infection
    • Solana, M. E., C. D. Alba Soto, M. C. Fernández, C. V. Poncini, M. Postan, and S. M. González Cappa. 2009. Reduction of parasite levels in blood improves pregnancy outcome during experimental Trypanosoma cruzi infection. Parasitology 136: 627-639.
    • (2009) Parasitology , vol.136 , pp. 627-639
    • Solana, M.E.1    Alba Soto, C.D.2    Fernández, M.C.3    Poncini, C.V.4    Postan, M.5    González Cappa, S.M.6
  • 44
    • 84858790272 scopus 로고    scopus 로고
    • Galectin-1 triggers an immunoregulatory signature in Th cells functionally defined by IL-10 expression
    • Cedeno-Laurent, F., M. Opperman, S. R. Barthel, V. K. Kuchroo, and C. J. Dimitroff. 2012. Galectin-1 triggers an immunoregulatory signature in Th cells functionally defined by IL-10 expression. J. Immunol. 188: 3127-3137.
    • (2012) J. Immunol. , vol.188 , pp. 3127-3137
    • Cedeno-Laurent, F.1    Opperman, M.2    Barthel, S.R.3    Kuchroo, V.K.4    Dimitroff, C.J.5
  • 45
    • 0036798269 scopus 로고    scopus 로고
    • Immunosuppression during acute Trypanosoma cruzi infection: Involvement of Ly6G (Gr1+)CD11b+ immature myeloid suppressor cells
    • Goñi, O., P. Alcaide, and M. Fresno. 2002. Immunosuppression during acute Trypanosoma cruzi infection: involvement of Ly6G (Gr1+)CD11b+ immature myeloid suppressor cells. Int. Immunol. 14: 1125-1134.
    • (2002) Int. Immunol. , vol.14 , pp. 1125-1134
    • Goñi, O.1    Alcaide, P.2    Fresno, M.3
  • 48
    • 84878898554 scopus 로고    scopus 로고
    • Analysis of the dynamics of infiltrating CD4+ T cell subsets in the heart during experimental Trypanosoma cruzi infection
    • Sanoja, C., S. Carbajosa, M. Fresno, and N. Gironès. 2013. Analysis of the dynamics of infiltrating CD4+ T cell subsets in the heart during experimental Trypanosoma cruzi infection. PLoS One 8: e65820.
    • (2013) PLoS One , vol.8 , pp. e65820
    • Sanoja, C.1    Carbajosa, S.2    Fresno, M.3    Gironès, N.4
  • 50
    • 0034963054 scopus 로고    scopus 로고
    • Antigalectin-1 autoantibodies in human Trypanosoma cruzi infection: Differential expression of this beta-galactoside-binding protein in cardiac Chagas' disease
    • Giordanengo, L., S. Gea, G. Barbieri, and G. A. Rabinovich. 2001. Antigalectin-1 autoantibodies in human Trypanosoma cruzi infection: differential expression of this beta-galactoside-binding protein in cardiac Chagas' disease. Clin. Exp. Immunol. 124: 266-273.
    • (2001) Clin. Exp. Immunol. , vol.124 , pp. 266-273
    • Giordanengo, L.1    Gea, S.2    Barbieri, G.3    Rabinovich, G.A.4
  • 54
    • 67649138829 scopus 로고    scopus 로고
    • Regulatory T cells in the control of hostmicroorganism interactions
    • Belkaid, Y., and K. Tarbell. 2009. Regulatory T cells in the control of hostmicroorganism interactions. Annu. Rev. Immunol. 27: 551-589.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 551-589
    • Belkaid, Y.1    Tarbell, K.2
  • 55
    • 0036884607 scopus 로고    scopus 로고
    • B7/CD28-dependent CD4+CD25+ regulatory T cells are essential components of the memory-protective immunity to Candida albicans
    • Montagnoli, C., A. Bacci, S. Bozza, R. Gaziano, P. Mosci, A. H. Sharpe, and L. Romani. 2002. B7/CD28-dependent CD4+CD25+ regulatory T cells are essential components of the memory-protective immunity to Candida albicans. J. Immunol. 169: 6298-6308.
    • (2002) J. Immunol. , vol.169 , pp. 6298-6308
    • Montagnoli, C.1    Bacci, A.2    Bozza, S.3    Gaziano, R.4    Mosci, P.5    Sharpe, A.H.6    Romani, L.7
  • 56
    • 2242423605 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
    • Belkaid, Y., C. A. Piccirillo, S. Mendez, E. M. Shevach, and D. L. Sacks. 2002. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature 420: 502-507.
    • (2002) Nature , vol.420 , pp. 502-507
    • Belkaid, Y.1    Piccirillo, C.A.2    Mendez, S.3    Shevach, E.M.4    Sacks, D.L.5
  • 58
    • 33846838637 scopus 로고    scopus 로고
    • Endogenous CD4+ CD25+ regulatory T cells have a limited role in the control of Trypanosoma cruzi infection in mice
    • Kotner, J., and R. Tarleton. 2007. Endogenous CD4+ CD25+ regulatory T cells have a limited role in the control of Trypanosoma cruzi infection in mice. Infect. Immun. 75: 861-869.
    • (2007) Infect. Immun. , vol.75 , pp. 861-869
    • Kotner, J.1    Tarleton, R.2
  • 61
    • 33750296886 scopus 로고    scopus 로고
    • Cooperative activation of TLR2 and bradykinin B2 receptor is required for induction of type 1 immunity in a mouse model of subcutaneous infection by Trypanosoma cruzi
    • Monteiro, A. C., V. Schmitz, E. Svensjo, R. T. Gazzinelli, I. C. Almeida, A. Todorov, L. B. de Arruda, A. C. Torrecilhas, J. B. Pesquero, A. Morrot, et al. 2006. Cooperative activation of TLR2 and bradykinin B2 receptor is required for induction of type 1 immunity in a mouse model of subcutaneous infection by Trypanosoma cruzi. J. Immunol. 177: 6325-6335.
    • (2006) J. Immunol. , vol.177 , pp. 6325-6335
    • Monteiro, A.C.1    Schmitz, V.2    Svensjo, E.3    Gazzinelli, R.T.4    Almeida, I.C.5    Todorov, A.6    De Arruda, L.B.7    Torrecilhas, A.C.8    Pesquero, J.B.9    Morrot, A.10
  • 62
    • 37349081546 scopus 로고    scopus 로고
    • Bradykinin B2 receptors of dendritic cells, acting as sensors of kinins proteolytically released by Trypanosoma cruzi, are critical for the development of protective type-1 responses
    • Monteiro, A. C., V. Schmitz, A. Morrot, L. B. de Arruda, F. Nagajyothi, A. Granato, J. B. Pesquero, W. Müller-Esterl, H. B. Tanowitz, and J. Scharfstein. 2007. Bradykinin B2 receptors of dendritic cells, acting as sensors of kinins proteolytically released by Trypanosoma cruzi, are critical for the development of protective type-1 responses. PLoS Pathog. 3: e185.
    • (2007) PLoS Pathog. , vol.3 , pp. e185
    • Monteiro, A.C.1    Schmitz, V.2    Morrot, A.3    De Arruda, L.B.4    Nagajyothi, F.5    Granato, A.6    Pesquero, J.B.7    Müller-Esterl, W.8    Tanowitz, H.B.9    Scharfstein, J.10
  • 63
    • 0025707153 scopus 로고
    • A major cysteine proteinase is developmentally regulated in Trypanosoma cruzi
    • Campetella, O., J. Martínez, and J. J. Cazzulo. 1990. A major cysteine proteinase is developmentally regulated in Trypanosoma cruzi. FEMS Microbiol. Lett. 55: 145-149.
    • (1990) FEMS Microbiol. Lett. , vol.55 , pp. 145-149
    • Campetella, O.1    Martínez, J.2    Cazzulo, J.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.