-
1
-
-
84864311450
-
Commensal bacteria calibrate the activation threshold of innate antiviral immunity
-
Abt, M.C., Osborne, L.C., Monticelli, L.A., Doering, T.A., Alenghat, T., Sonnenberg, G.F., Paley, M.A., Antenus, M., Williams, K.L., Erikson, J., et al. (2012). Commensal bacteria calibrate the activation threshold of innate antiviral immunity. Immunity 37, 158-170.
-
(2012)
Immunity
, vol.37
, pp. 158-170
-
-
Abt, M.C.1
Osborne, L.C.2
Monticelli, L.A.3
Doering, T.A.4
Alenghat, T.5
Sonnenberg, G.F.6
Paley, M.A.7
Antenus, M.8
Williams, K.L.9
Erikson, J.10
-
2
-
-
79953061608
-
Human TLRs and IL-1Rs in host defense: natural insights from evolutionary, epidemiological, and clinical genetics
-
Casanova, J.L., Abel, L., and Quintana-Murci, L. (2011). Human TLRs and IL-1Rs in host defense: natural insights from evolutionary, epidemiological, and clinical genetics. Annu. Rev. Immunol. 29, 447-491.
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 447-491
-
-
Casanova, J.L.1
Abel, L.2
Quintana-Murci, L.3
-
3
-
-
76249120134
-
Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity
-
Clarke, T.B., Davis, K.M., Lysenko, E.S., Zhou, A.Y., Yu, Y., and Weiser, J.N. (2010). Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity. Nat. Med. 16, 228-231.
-
(2010)
Nat. Med.
, vol.16
, pp. 228-231
-
-
Clarke, T.B.1
Davis, K.M.2
Lysenko, E.S.3
Zhou, A.Y.4
Yu, Y.5
Weiser, J.N.6
-
4
-
-
4644345036
-
Tumor-infiltrating dendritic cell precursors recruited by a betadefensin contribute to vasculogenesis under the influence of Vegf-A
-
Conejo-Garcia, J.R., Benencia, F., Courreges, M.C., Kang, E., Mohamed-Hadley, A., Buckanovich, R.J., Holtz, D.O., Jenkins, A., Na, H., Zhang, L., et al. (2004). Tumor-infiltrating dendritic cell precursors recruited by a betadefensin contribute to vasculogenesis under the influence of Vegf-A. Nat. Med. 10, 950-958.
-
(2004)
Nat. Med.
, vol.10
, pp. 950-958
-
-
Conejo-Garcia, J.R.1
Benencia, F.2
Courreges, M.C.3
Kang, E.4
Mohamed-Hadley, A.5
Buckanovich, R.J.6
Holtz, D.O.7
Jenkins, A.8
Na, H.9
Zhang, L.10
-
5
-
-
68849112640
-
Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity
-
Cubillos-Ruiz, J.R., Engle, X., Scarlett, U.K., Martinez, D., Barber, A., Elgueta, R., Wang, L., Nesbeth, Y., Durant, Y., Gewirtz, A.T., et al. (2009). Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity. J. Clin. Invest. 119, 2231-2244.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 2231-2244
-
-
Cubillos-Ruiz, J.R.1
Engle, X.2
Scarlett, U.K.3
Martinez, D.4
Barber, A.5
Elgueta, R.6
Wang, L.7
Nesbeth, Y.8
Durant, Y.9
Gewirtz, A.T.10
-
6
-
-
84873449312
-
Targeting galectin-1 overcomes breast cancerassociated immunosuppression and prevents metastatic disease
-
Dalotto-Moreno, T., Croci, D.O., Cerliani, J.P., Martinez-Allo, V.C., Dergan-Dylon, S., Méndez-Huergo, S.P., Stupirski, J.C., Mazal, D., Osinaga, E., Toscano, M.A., et al. (2013). Targeting galectin-1 overcomes breast cancerassociated immunosuppression and prevents metastatic disease. Cancer Res. 73, 1107-1117.
-
(2013)
Cancer Res.
, vol.73
, pp. 1107-1117
-
-
Dalotto-Moreno, T.1
Croci, D.O.2
Cerliani, J.P.3
Martinez-Allo, V.C.4
Dergan-Dylon, S.5
Méndez-Huergo, S.P.6
Stupirski, J.C.7
Mazal, D.8
Osinaga, E.9
Toscano, M.A.10
-
7
-
-
33646866567
-
Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease
-
Gewirtz, A.T., Vijay-Kumar, M., Brant, S.R., Duerr, R.H., Nicolae, D.L., and Cho, J.H. (2006). Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease. Am. J. Physiol. Gastrointest. Liver Physiol. 290, G1157-G1163.
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.290
, pp. G1157-G1163
-
-
Gewirtz, A.T.1
Vijay-Kumar, M.2
Brant, S.R.3
Duerr, R.H.4
Nicolae, D.L.5
Cho, J.H.6
-
8
-
-
10744226016
-
A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease
-
Hawn, T.R., Verbon, A., Lettinga, K.D., Zhao, L.P., Li, S.S., Laws, R.J., Skerrett, S.J., Beutler, B., Schroeder, L., Nachman, A., et al. (2003). A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease. J. Exp. Med. 198, 1563-1572.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1563-1572
-
-
Hawn, T.R.1
Verbon, A.2
Lettinga, K.D.3
Zhao, L.P.4
Li, S.S.5
Laws, R.J.6
Skerrett, S.J.7
Beutler, B.8
Schroeder, L.9
Nachman, A.10
-
9
-
-
67650105333
-
Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women
-
Hawn, T.R., Scholes, D., Li, S.S., Wang, H., Yang, Y., Roberts, P.L., Stapleton, A.E., Janer, M., Aderem, A., Stamm, W.E., et al. (2009). Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women. PLoS ONE 4, e5990.
-
(2009)
PLoS ONE
, vol.4
-
-
Hawn, T.R.1
Scholes, D.2
Li, S.S.3
Wang, H.4
Yang, Y.5
Roberts, P.L.6
Stapleton, A.E.7
Janer, M.8
Aderem, A.9
Stamm, W.E.10
-
10
-
-
34249017939
-
Prevalence of CARD15/NOD2 mutations in Caucasian healthy people
-
Hugot, J.P., Zaccaria, I., Cavanaugh, J., Yang, H., Vermeire, S., Lappalainen, M., Schreiber, S., Annese, V., Jewell, D.P., Fowler, E.V., et al.; IBD International Genetics Consortium (2007). Prevalence of CARD15/NOD2 mutations in Caucasian healthy people. Am. J. Gastroenterol. 102, 1259-1267.
-
(2007)
Am. J. Gastroenterol.
, vol.102
, pp. 1259-1267
-
-
Hugot, J.P.1
Zaccaria, I.2
Cavanaugh, J.3
Yang, H.4
Vermeire, S.5
Lappalainen, M.6
Schreiber, S.7
Annese, V.8
Jewell, D.P.9
Fowler, E.V.10
-
11
-
-
84888049920
-
Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment
-
Iida, N., Dzutsev, A., Stewart, C.A., Smith, L., Bouladoux, N., Weingarten, R.A., Molina, D.A., Salcedo, R., Back, T., Cramer, S., et al. (2013). Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment. Science 342, 967-970.
-
(2013)
Science
, vol.342
, pp. 967-970
-
-
Iida, N.1
Dzutsev, A.2
Stewart, C.A.3
Smith, L.4
Bouladoux, N.5
Weingarten, R.A.6
Molina, D.A.7
Salcedo, R.8
Back, T.9
Cramer, S.10
-
12
-
-
0035893252
-
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
-
Jackson, E.L., Willis, N., Mercer, K., Bronson, R.T., Crowley, D., Montoya, R., Jacks, T., and Tuveson, D.A. (2001). Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. Genes Dev. 15, 3243-3248.
-
(2001)
Genes Dev.
, vol.15
, pp. 3243-3248
-
-
Jackson, E.L.1
Willis, N.2
Mercer, K.3
Bronson, R.T.4
Crowley, D.5
Montoya, R.6
Jacks, T.7
Tuveson, D.A.8
-
13
-
-
0035734285
-
Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
-
Jonkers, J., Meuwissen, R., van der Gulden, H., Peterse, H., van der Valk, M., and Berns, A. (2001). Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Nat. Genet. 29, 418-425.
-
(2001)
Nat. Genet.
, vol.29
, pp. 418-425
-
-
Jonkers, J.1
Meuwissen, R.2
van der Gulden, H.3
Peterse, H.4
van der Valk, M.5
Berns, A.6
-
14
-
-
69849107597
-
Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments
-
Kryczek, I., Banerjee, M., Cheng, P., Vatan, L., Szeliga, W., Wei, S., Huang, E., Finlayson, E., Simeone, D., Welling, T.H., et al. (2009). Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood 114, 1141-1149.
-
(2009)
Blood
, vol.114
, pp. 1141-1149
-
-
Kryczek, I.1
Banerjee, M.2
Cheng, P.3
Vatan, L.4
Szeliga, W.5
Wei, S.6
Huang, E.7
Finlayson, E.8
Simeone, D.9
Welling, T.H.10
-
15
-
-
44449106055
-
A microbial symbiosis factor prevents intestinal inflammatory disease
-
Mazmanian, S.K., Round, J.L., and Kasper, D.L. (2008). A microbial symbiosis factor prevents intestinal inflammatory disease. Nature 453, 620-625.
-
(2008)
Nature
, vol.453
, pp. 620-625
-
-
Mazmanian, S.K.1
Round, J.L.2
Kasper, D.L.3
-
16
-
-
39549123040
-
Toll-like receptor polymorphisms and susceptibility to human diseas
-
(London, England: 1979)
-
Misch, E., and Hawn, T. (2008). Toll-like receptor polymorphisms and susceptibility to human disease. Clinical science (London, England: 1979) 114, 347-360.
-
(2008)
Clinical science
, vol.114
, pp. 347-360
-
-
Misch, E.1
Hawn, T.2
-
17
-
-
34548024379
-
Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway
-
Peng, G., Wang, H.Y., Peng, W., Kiniwa, Y., Seo, K.H., and Wang, R.F. (2007). Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique toll-like receptor signaling pathway. Immunity 27, 334-348.
-
(2007)
Immunity
, vol.27
, pp. 334-348
-
-
Peng, G.1
Wang, H.Y.2
Peng, W.3
Kiniwa, Y.4
Seo, K.H.5
Wang, R.F.6
-
18
-
-
84858766894
-
Regulatory circuits mediated by lectin-glycan interactions in autoimmunity and cancer
-
Rabinovich, G.A., and Croci, D.O. (2012). Regulatory circuits mediated by lectin-glycan interactions in autoimmunity and cancer. Immunity 36, 322-335.
-
(2012)
Immunity
, vol.36
, pp. 322-335
-
-
Rabinovich, G.A.1
Croci, D.O.2
-
19
-
-
12144285871
-
Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumorimmune privilege
-
Rubinstein, N., Alvarez, M., Zwirner, N.W., Toscano, M.A., Ilarregui, J.M., Bravo, A., Mordoh, J., Fainboim, L., Podhajcer, O.L., and Rabinovich, G.A. (2004). Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumorimmune privilege. Cancer Cell 5, 241-251.
-
(2004)
Cancer Cell
, vol.5
, pp. 241-251
-
-
Rubinstein, N.1
Alvarez, M.2
Zwirner, N.W.3
Toscano, M.A.4
Ilarregui, J.M.5
Bravo, A.6
Mordoh, J.7
Fainboim, L.8
Podhajcer, O.L.9
Rabinovich, G.A.10
-
20
-
-
84922228853
-
Initiation of metastatic breast carcinoma by targeting of the ductal epithelium with adenovirus-cre: a novel transgenic mouse model of breast cancer.
-
Rutkowski, M.R., Allegrezza, M.J., Svoronos, N., Tesone, A.J., Stephen, T.L., Perales-Puchalt, A., Nguyen, J., Zhang, P.J., Fiering, S.N., Tchou, J., and Conejo-Garcia, J.R. (2014). Initiation of metastatic breast carcinoma by targeting of the ductal epithelium with adenovirus-cre: a novel transgenic mouse model of breast cancer. J. Vis. Exp. 26.
-
(2014)
J. Vis. Exp.
, pp. 26
-
-
Rutkowski, M.R.1
Allegrezza, M.J.2
Svoronos, N.3
Tesone, A.J.4
Stephen, T.L.5
Perales-Puchalt, A.6
Nguyen, J.7
Zhang, P.J.8
Fiering, S.N.9
Tchou, J.10
Conejo-Garcia, J.R.11
-
21
-
-
82755162136
-
Adenosinergic regulation of the expansion and immunosuppressive activity of CD11b+Gr1+ cells
-
Ryzhov, S., Novitskiy, S.V., Goldstein, A.E., Biktasova, A., Blackburn, M.R., Biaggioni, I., Dikov, M.M., and Feoktistov, I. (2011). Adenosinergic regulation of the expansion and immunosuppressive activity of CD11b+Gr1+ cells. J. Immunol. 187, 6120-6129.
-
(2011)
J. Immunol.
, vol.187
, pp. 6120-6129
-
-
Ryzhov, S.1
Novitskiy, S.V.2
Goldstein, A.E.3
Biktasova, A.4
Blackburn, M.R.5
Biaggioni, I.6
Dikov, M.M.7
Feoktistov, I.8
-
22
-
-
84859845998
-
A TLR5 (g.1174C > T) variant that encodes a stop codon (R392X) is associated with bronchopulmonary dysplasia
-
Sampath, V., Garland, J.S., Le, M., Patel, A.L., Konduri, G.G., Cohen, J.D., Simpson, P.M., and Hines, R.N. (2012). A TLR5 (g.1174C > T) variant that encodes a stop codon (R392X) is associated with bronchopulmonary dysplasia. Pediatr. Pulmonol. 47, 460-468.
-
(2012)
Pediatr. Pulmonol.
, vol.47
, pp. 460-468
-
-
Sampath, V.1
Garland, J.S.2
Le, M.3
Patel, A.L.4
Konduri, G.G.5
Cohen, J.D.6
Simpson, P.M.7
Hines, R.N.8
-
23
-
-
84858793263
-
Ovarian cancer progression is controlled by phenotypic changes in dendritic cells
-
Scarlett, U.K., Rutkowski, M.R., Rauwerdink, A.M., Fields, J., Escovar-Fadul, X., Baird, J., Cubillos-Ruiz, J.R., Jacobs, A.C., Gonzalez, J.L., Weaver, J., et al. (2012). Ovarian cancer progression is controlled by phenotypic changes in dendritic cells. J. Exp. Med. 209, 495-506.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 495-506
-
-
Scarlett, U.K.1
Rutkowski, M.R.2
Rauwerdink, A.M.3
Fields, J.4
Escovar-Fadul, X.5
Baird, J.6
Cubillos-Ruiz, J.R.7
Jacobs, A.C.8
Gonzalez, J.L.9
Weaver, J.10
-
24
-
-
34547099820
-
Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death
-
Toscano, M.A., Bianco, G.A., Ilarregui, J.M., Croci, D.O., Correale, J., Hernandez, J.D., Zwirner, N.W., Poirier, F., Riley, E.M., Baum, L.G., and Rabinovich, G.A. (2007). Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death. Nat. Immunol. 8, 825-834.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 825-834
-
-
Toscano, M.A.1
Bianco, G.A.2
Ilarregui, J.M.3
Croci, D.O.4
Correale, J.5
Hernandez, J.D.6
Zwirner, N.W.7
Poirier, F.8
Riley, E.M.9
Baum, L.G.10
Rabinovich, G.A.11
-
25
-
-
84888059687
-
The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide
-
Viaud, S., Saccheri, F., Mignot, G., Yamazaki, T., Daillère, R., Hannani, D., Enot, D.P., Pfirschke, C., Engblom, C., Pittet, M.L., et al. (2013). The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science 342, 971-976.
-
(2013)
Science
, vol.342
, pp. 971-976
-
-
Viaud, S.1
Saccheri, F.2
Mignot, G.3
Yamazaki, T.4
Daillère, R.5
Hannani, D.6
Enot, D.P.7
Pfirschke, C.8
Engblom, C.9
Pittet, M.L.10
-
26
-
-
67650495415
-
IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway
-
Wang, L., Yi, T., Kortylewski, M., Pardoll, D.M., Zeng, D., and Yu, H. (2009). IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway. J. Exp. Med. 206, 1457-1464.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1457-1464
-
-
Wang, L.1
Yi, T.2
Kortylewski, M.3
Pardoll, D.M.4
Zeng, D.5
Yu, H.6
|