DUSP1 alleviates cardiac ischemia/reperfusion injury by suppressing the Mff-required mitochondrial fission and Bnip3-related mitophagy via the JNK pathways

Redox Biology

Volumn 14, Issue , 2018, Pages 576-587

  Jin, Qinhua ^a   Li, Ruibing ^a,c   Hu, Nan ^d   Xin, Ting ^a,b   Zhu, Pingjun ^a   Hu, Shunying ^a   Ma, Sai ^d   Zhu, Hong ^d   Ren, Jun ^d   Zhou, Hao ^a,d  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b TIANJIN FIRST CENTRAL HOSPITAL   (China)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Wyoming University   (United States)

Author keywords

Bnip3; Cardiac IR injury; DUSP1; JNK; Mff; Mitochondrial fission; Mitophagy

Indexed keywords

MEMBRANE PROTEIN; MITOCHONDRIAL FISSION FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; PROTEIN BNIP3; UNCLASSIFIED DRUG; BNIP3 PROTEIN, MOUSE; DUSP1 PROTEIN, MOUSE; MITOCHONDRIAL FISSION FACTOR, MOUSE; MITOCHONDRIAL PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL DAMAGE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME DEFICIENCY; ENZYME REGULATION; HEART FUNCTION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART STRESS; IN VITRO STUDY; IN VIVO STUDY; METABOLIC DISORDER; MITOCHONDRIAL RESPIRATION; MITOPHAGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; SURVIVAL; UPREGULATION; WILD TYPE; ANIMAL; CARDIAC MUSCLE; HEART MITOCHONDRION; MAPK SIGNALING; METABOLISM; MITOCHONDRIAL DYNAMICS; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; PATHOLOGY; TRANSGENIC MOUSE;

ANIMALS; DUAL SPECIFICITY PHOSPHATASE 1; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MICE, TRANSGENIC; MITOCHONDRIA, HEART; MITOCHONDRIAL DEGRADATION; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL PROTEINS; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM;

EID: 85034088701     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2017.11.004     Document Type: Article

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