Berberine alleviates cardiac ischemia/reperfusion injury by inhibiting excessive autophagy in cardiomyocytes

European Journal of Pharmacology

Volumn 762, Issue , 2015, Pages 1-10

  Huang, Zhouqing ^a   Han, Zhihua ^b   Ye, Bozhi ^a   Dai, Zhenyu ^a   Shan, Peiren ^a   Lu, Zhongqiu ^a   Dai, Kezhi ^a   Wang, Changqian ^b   Huang, Weijian ^a  

^a THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^b SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

Author keywords

AMPK; Autophagy; Berberine; Heart; Ischemia reperfusion injury

Indexed keywords

BECLIN 1; BERBERINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PEROXIDASE; PROTEIN BNIP3; SIRTUIN 1; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE; TOR COMPLEX 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CORRELATIONAL STUDY; DEPHOSPHORYLATION; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG STRUCTURE; ENZYME ACTIVITY; GENE EXPRESSION; HEART FUNCTION; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART PROTECTION; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; SINGLE DRUG DOSE; ANIMAL; APOPTOSIS; C57BL MOUSE; CARDIAC MUSCLE CELL; CELL LINE; CELL PROTECTION; CONVALESCENCE; DRUG EFFECTS; METABOLISM; MYOCARDIAL REPERFUSION INJURY; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; APOPTOSIS; AUTOPHAGY; BERBERINE; CELL LINE; CYTOPROTECTION; MALE; MICE; MICE, INBRED C57BL; MULTIPROTEIN COMPLEXES; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; PHOSPHORYLATION; RECOVERY OF FUNCTION; TOR SERINE-THREONINE KINASES;

EID: 84929624343     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.05.028     Document Type: Article

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