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Volumn 60, Issue 2, 2016, Pages 167-177

Melatonin suppression of aerobic glycolysis (Warburg effect), survival signalling and metastasis in human leiomyosarcoma

Author keywords

leiomyosarcoma; melatonin; metastasis; signalling pathways; Warburg effect

Indexed keywords

CYCLIC AMP; DNA; GLYCOGEN SYNTHASE KINASE 3BETA; LINOLEIC ACID; MELATONIN; MITOGEN ACTIVATED PROTEIN KINASE 14; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN HYDROLYSATE; PROTEIN KINASE B; TRANSCRIPTION FACTOR RELA;

EID: 84956873099     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/jpi.12298     Document Type: Article
Times cited : (74)

References (36)
  • 2
    • 84927572152 scopus 로고    scopus 로고
    • Clinical features of leiomyosarcoma of the urinary bladder: Analysis of 183 cases
    • Rodriguez D, Preston MA, Barrisford GW, et al., Clinical features of leiomyosarcoma of the urinary bladder: analysis of 183 cases. Urol Oncol 2014; 32: 958-965.
    • (2014) Urol Oncol , vol.32 , pp. 958-965
    • Rodriguez, D.1    Preston, M.A.2    Barrisford, G.W.3
  • 3
    • 84902303839 scopus 로고    scopus 로고
    • Locally-advanced unresected uterine leiomyosarcoma with triple-modality treatment combining radiotherapy, chemotherapy and hyperthermia: A case report
    • Shirafuji A, Shinagawa A, Kurokawa T, et al., Locally-advanced unresected uterine leiomyosarcoma with triple-modality treatment combining radiotherapy, chemotherapy and hyperthermia: a case report. Oncol Lett 2014; 8: 637-641.
    • (2014) Oncol Lett , vol.8 , pp. 637-641
    • Shirafuji, A.1    Shinagawa, A.2    Kurokawa, T.3
  • 4
    • 70350228630 scopus 로고    scopus 로고
    • Therapeutic potential of hepatocyte growth factor/scatter factor neutralizing antibodies: Inhibition of tumor growth in both autocrine and paracrine hepatocyte growth factor/scatter factor:c-Met-driven models of leiomyosarcoma
    • Gao CF, Xie Q, Zhang YW, et al., Therapeutic potential of hepatocyte growth factor/scatter factor neutralizing antibodies: inhibition of tumor growth in both autocrine and paracrine hepatocyte growth factor/scatter factor:c-Met-driven models of leiomyosarcoma. Mol Cancer Ther 2009; 8: 2803-2810.
    • (2009) Mol Cancer Ther , vol.8 , pp. 2803-2810
    • Gao, C.F.1    Xie, Q.2    Zhang, Y.W.3
  • 5
    • 77956519685 scopus 로고    scopus 로고
    • Hepatocyte growth factor activator inhibitors (HAI-1 and HAI-2) are potential targets in uterine leiomyosarcoma
    • Nakamura K, Abarzua F, Hongo A, et al., Hepatocyte growth factor activator inhibitors (HAI-1 and HAI-2) are potential targets in uterine leiomyosarcoma. Int J Oncol 2010; 37: 605-614.
    • (2010) Int J Oncol , vol.37 , pp. 605-614
    • Nakamura, K.1    Abarzua, F.2    Hongo, A.3
  • 6
    • 19944430738 scopus 로고    scopus 로고
    • Enhanced growth of human met-expressing xenografts in a new strain of immunocompromised mice transgenic for human hepatocyte growth factor/scatter factor
    • Zhang YW, Su Y, Lanning N, et al., Enhanced growth of human met-expressing xenografts in a new strain of immunocompromised mice transgenic for human hepatocyte growth factor/scatter factor. Oncogene 2005; 24: 101-106.
    • (2005) Oncogene , vol.24 , pp. 101-106
    • Zhang, Y.W.1    Su, Y.2    Lanning, N.3
  • 7
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA,. The hallmarks of cancer. Cell 2000; 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 8
    • 84858604270 scopus 로고    scopus 로고
    • Metabolic reprogramming: A cancer hallmark even Warburg did not anticipate
    • Ward PS, Thompson CB,. Metabolic reprogramming: a cancer hallmark even Warburg did not anticipate. Cancer Cell 2012; 21: 297-307.
    • (2012) Cancer Cell , vol.21 , pp. 297-307
    • Ward, P.S.1    Thompson, C.B.2
  • 9
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O,. On the origin of cancer cells. Science 1956; 123: 309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 10
    • 84910028645 scopus 로고    scopus 로고
    • Loss of GLUT4 induces metabolic reprogramming and impairs viability of breast cancer cells
    • Garrido P, Osorio FG, Moran J, et al., Loss of GLUT4 induces metabolic reprogramming and impairs viability of breast cancer cells. J Cell Physiol 2015; 230: 191-198.
    • (2015) J Cell Physiol , vol.230 , pp. 191-198
    • Garrido, P.1    Osorio, F.G.2    Moran, J.3
  • 11
    • 84255162057 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism
    • Hitosugi T, Fan J, Chung TW, et al., Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism. Mol Cell 2011; 44: 864-877.
    • (2011) Mol Cell , vol.44 , pp. 864-877
    • Hitosugi, T.1    Fan, J.2    Chung, T.W.3
  • 13
    • 67649992027 scopus 로고    scopus 로고
    • Antineoplastic effects of melatonin on a rare malignancy of mesenchymal origin: Melatonin receptor-mediated inhibition of signal transduction, linoleic acid metabolism and growth in tissue-isolated human leiomyosarcoma xenografts
    • Dauchy RT, Blask DE, Dauchy EM, et al., Antineoplastic effects of melatonin on a rare malignancy of mesenchymal origin: melatonin receptor-mediated inhibition of signal transduction, linoleic acid metabolism and growth in tissue-isolated human leiomyosarcoma xenografts. J Pineal Res 2009; 47: 32-42.
    • (2009) J Pineal Res , vol.47 , pp. 32-42
    • Dauchy, R.T.1    Blask, D.E.2    Dauchy, E.M.3
  • 14
    • 0002825153 scopus 로고    scopus 로고
    • An overview of the neuroendocrine regulation of experimental tumor growth by melatonin and its analogs and the therapeutic use of melatonin in oncology
    • Bartsch C. Bartsch H. Blask D.E. et al., eds., Springer-Verlag, Berlin Heidelberg
    • Blask DE,. An overview of the neuroendocrine regulation of experimental tumor growth by melatonin and its analogs and the therapeutic use of melatonin in oncology. In: The Pineal Gland and Cancer, Bartsch C, Bartsch H, Blask DE, et al., eds., Springer-Verlag, Berlin Heidelberg, 2001; pp. 309-335.
    • (2001) The Pineal Gland and Cancer , pp. 309-335
    • Blask, D.E.1
  • 15
    • 84905501655 scopus 로고    scopus 로고
    • Circadian and melatonin disruption by exposure to light at night drives intrinsic resistance to tamoxifen therapy in breast cancer
    • Dauchy RT, Xiang S, Mao L, et al., Circadian and melatonin disruption by exposure to light at night drives intrinsic resistance to tamoxifen therapy in breast cancer. Cancer Res 2014; 74: 4099-4110.
    • (2014) Cancer Res , vol.74 , pp. 4099-4110
    • Dauchy, R.T.1    Xiang, S.2    Mao, L.3
  • 16
    • 28244481148 scopus 로고    scopus 로고
    • Melatonin-depleted blood from premenopausal women exposed to light at night stimulates growth of human breast cancer xenografts in nude rats
    • Blask DE, Brainard GC, Dauchy RT, et al., Melatonin-depleted blood from premenopausal women exposed to light at night stimulates growth of human breast cancer xenografts in nude rats. Cancer Res 2005; 65: 11174-11184.
    • (2005) Cancer Res , vol.65 , pp. 11174-11184
    • Blask, D.E.1    Brainard, G.C.2    Dauchy, R.T.3
  • 17
    • 84868107443 scopus 로고    scopus 로고
    • Circadian gating of epithelial-to-mesenchymal transition in breast cancer cells via melatonin-regulation of GSK3β
    • Mao L, Dauchy RT, Blask DE,. Circadian gating of epithelial-to-mesenchymal transition in breast cancer cells via melatonin-regulation of GSK3β. Mol Endocrinol 2012; 26: 1808-1820.
    • (2012) Mol Endocrinol , vol.26 , pp. 1808-1820
    • Mao, L.1    Dauchy, R.T.2    Blask, D.E.3
  • 18
    • 0037174920 scopus 로고    scopus 로고
    • Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate. Alteration in peroxisome proliferator-activated receptor gamma
    • Hsi LC, Wilson LC, Eling TE,. Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate. Alteration in peroxisome proliferator-activated receptor gamma. J Biol Chem 2002; 277: 40549-40556.
    • (2002) J Biol Chem , vol.277 , pp. 40549-40556
    • Hsi, L.C.1    Wilson, L.C.2    Eling, T.E.3
  • 19
    • 84858019563 scopus 로고    scopus 로고
    • Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways
    • Yan D, Avtanksi D, Saxena NK, et al., Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways. J Biol Chem 2012; 287: 8598-8612.
    • (2012) J Biol Chem , vol.287 , pp. 8598-8612
    • Yan, D.1    Avtanksi, D.2    Saxena, N.K.3
  • 20
    • 0030994681 scopus 로고    scopus 로고
    • A mathematical model of diurnal variations in human plasma melatonin levels
    • Brown EN, Choe Y, Shanahan TL, et al., A mathematical model of diurnal variations in human plasma melatonin levels. Am J Physiol 1997; 272: E506-E516.
    • (1997) Am J Physiol , vol.272 , pp. E506-E516
    • Brown, E.N.1    Choe, Y.2    Shanahan, T.L.3
  • 21
    • 0023698530 scopus 로고
    • Effects of the pineal hormone melatonin on the proliferation and morphological characteristics of human breast cancer cells (MCF-7) in culture
    • Hill SM, Blask DE,. Effects of the pineal hormone melatonin on the proliferation and morphological characteristics of human breast cancer cells (MCF-7) in culture. Cancer Res 1988; 48: 6121-6126.
    • (1988) Cancer Res , vol.48 , pp. 6121-6126
    • Hill, S.M.1    Blask, D.E.2
  • 22
    • 80053552019 scopus 로고    scopus 로고
    • Melatonin and associated signaling pathways that control normal breast epithelium and breast cancer
    • Hill SM, Blask DE, Xiang S, et al., Melatonin and associated signaling pathways that control normal breast epithelium and breast cancer. J Mammary Gland Biol Neoplasia 2011; 16: 235-245.
    • (2011) J Mammary Gland Biol Neoplasia , vol.16 , pp. 235-245
    • Hill, S.M.1    Blask, D.E.2    Xiang, S.3
  • 23
    • 84875459340 scopus 로고    scopus 로고
    • Proliferation-independent control of tumor glycolysis by PDGFR-mediated AKT activation
    • Ran C, Liu H, Hitoshi Y, et al., Proliferation-independent control of tumor glycolysis by PDGFR-mediated AKT activation. Cancer Res 2013; 73: 1831-1843.
    • (2013) Cancer Res , vol.73 , pp. 1831-1843
    • Ran, C.1    Liu, H.2    Hitoshi, Y.3
  • 24
    • 84934296827 scopus 로고    scopus 로고
    • Doxorubicin resistance in breast cancer is driven by light at night-induced disruption of the circadian melatonin signal
    • Xiang S, Dauchy RT, Hauch A, et al., Doxorubicin resistance in breast cancer is driven by light at night-induced disruption of the circadian melatonin signal. J Pineal Res 2015; 59: 60-69.
    • (2015) J Pineal Res , vol.59 , pp. 60-69
    • Xiang, S.1    Dauchy, R.T.2    Hauch, A.3
  • 25
    • 79960425073 scopus 로고    scopus 로고
    • Inhibition of breast cancer cell invasion by melatonin is mediated through regulation of the p38 mitogen-activated protein kinase signaling pathway
    • Mao L, Yuan L, Slakey LM, et al., Inhibition of breast cancer cell invasion by melatonin is mediated through regulation of the p38 mitogen-activated protein kinase signaling pathway. Breast Cancer Res 2010; 12: R107.
    • (2010) Breast Cancer Res , vol.12 , pp. R107
    • Mao, L.1    Yuan, L.2    Slakey, L.M.3
  • 26
    • 77957288981 scopus 로고    scopus 로고
    • A differentiation-based microRNA signature identifies leiomyosarcoma as a mesenchymal stem cell malignancy
    • Danielson LS, Menendex S, Attolinini CS, et al., A differentiation-based microRNA signature identifies leiomyosarcoma as a mesenchymal stem cell malignancy. Am J Pathol 2010; 177: 908-917.
    • (2010) Am J Pathol , vol.177 , pp. 908-917
    • Danielson, L.S.1    Menendex, S.2    Attolinini, C.S.3
  • 27
    • 20744439516 scopus 로고    scopus 로고
    • The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it
    • Hay ED,. The mesenchymal cell, its role in the embryo, and the remarkable signaling mechanisms that create it. Dev Dyn 2005; 3: 706-720.
    • (2005) Dev Dyn , vol.3 , pp. 706-720
    • Hay, E.D.1
  • 28
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery JP,. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2002; 2: 442-454.
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 29
    • 28144440871 scopus 로고    scopus 로고
    • Changes in cytoskeletal protein composition indicative of an epithelial-mesenchymal transition in human micrometastatic and primary breast carcinoma cells
    • Willipinski-Stapelfedt B, Reithdorf S, Assmann V, et al., Changes in cytoskeletal protein composition indicative of an epithelial-mesenchymal transition in human micrometastatic and primary breast carcinoma cells. Clin Cancer Res 2005; 11: 8006-8014.
    • (2005) Clin Cancer Res , vol.11 , pp. 8006-8014
    • Willipinski-Stapelfedt, B.1    Reithdorf, S.2    Assmann, V.3
  • 32
    • 0037504665 scopus 로고    scopus 로고
    • Transactivation of vimentin by β-catenin in human breast cancer cells
    • Gilles C, Polette M, Mestdagt M, et al., Transactivation of vimentin by β-catenin in human breast cancer cells. Cancer Res 2003; 63: 2658-2664.
    • (2003) Cancer Res , vol.63 , pp. 2658-2664
    • Gilles, C.1    Polette, M.2    Mestdagt, M.3
  • 33
    • 79952283136 scopus 로고    scopus 로고
    • Inhibition of c-Met down-regulates TIGAR expression and reduces NADPH production leading to cell death
    • Lui VW, Wong EY, Ho K, et al., Inhibition of c-Met down-regulates TIGAR expression and reduces NADPH production leading to cell death. Oncogene 2011; 30: 1127-1134.
    • (2011) Oncogene , vol.30 , pp. 1127-1134
    • Lui, V.W.1    Wong, E.Y.2    Ho, K.3
  • 34
    • 84925482726 scopus 로고    scopus 로고
    • ROS and energy metabolism in cancer cells: Alliance for fast growth
    • Kang SW, Lee S, Lee EK,. ROS and energy metabolism in cancer cells: alliance for fast growth. Arch Pharm Res 2015; 38: 338-345.
    • (2015) Arch Pharm Res , vol.38 , pp. 338-345
    • Kang, S.W.1    Lee, S.2    Lee, E.K.3
  • 35
    • 84929305819 scopus 로고    scopus 로고
    • Expression and phosphorylation of the AS160v2 splice variant supports GLUT4 activation and the Warburg effect in multiple myeloma
    • Cheng JC, McBrayer SK, Coarfa C, et al., Expression and phosphorylation of the AS160v2 splice variant supports GLUT4 activation and the Warburg effect in multiple myeloma. Cancer Metab 2013; 1: 14.
    • (2013) Cancer Metab , vol.1 , pp. 14
    • Cheng, J.C.1    McBrayer, S.K.2    Coarfa, C.3
  • 36
    • 84905472527 scopus 로고    scopus 로고
    • Light exposure at night disrupts host/cancer circadian regulatory dynamics: Impact on the Warburg effect, lipid signaling and tumor growth prevention
    • Blask DE, Dauchy RT, Dauchy EM, et al., Light exposure at night disrupts host/cancer circadian regulatory dynamics: impact on the Warburg effect, lipid signaling and tumor growth prevention. PLoS One 2014; 9: e102776.
    • (2014) PLoS One , vol.9 , pp. e102776
    • Blask, D.E.1    Dauchy, R.T.2    Dauchy, E.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.