Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers

eLife

Volumn 6, Issue , 2017, Pages

  Kelso, Timothy W R ^a   Porter, Devin K ^a   Amaral, Maria Luisa ^a   Shokhirev, Maxim N ^a   Benner, Christopher ^b   Hargreaves, Diana C ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; RETINOBLASTOMA BINDING PROTEIN 1; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR; ARID1A PROTEIN, HUMAN; ARID1B PROTEIN, HUMAN; DNA BINDING PROTEIN; HISTONE; MUTANT PROTEIN; NUCLEAR PROTEIN;

ARTICLE; CANCER GROWTH; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; ENHANCER REGION; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; HIGH THROUGHPUT SCREENING; HUMAN; IMMUNOBLOTTING; LETHAL MUTATION; MALIGNANT NEOPLASM; MOLECULAR GENETICS; NUCLEOSOME; OVARY CANCER; PROTEIN MOTIF; RNA ISOLATION; GENETICS; METABOLISM; NEOPLASM; PATHOLOGY; PROTEIN PROCESSING; TUMOR CELL LINE;

CELL LINE, TUMOR; CHROMATIN; DNA-BINDING PROTEINS; HISTONES; HUMANS; MUTANT PROTEINS; NEOPLASMS; NUCLEAR PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SYNTHETIC LETHAL MUTATIONS; TRANSCRIPTION FACTORS;

EID: 85032929524     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.30506.001     Document Type: Article

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