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Volumn 16, Issue 7, 2015, Pages 775-784

The chromatin remodeler Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth

Author keywords

[No Author keywords available]

Indexed keywords

BRG1 PROTEIN; IMMUNOGLOBULIN HEAVY CHAIN; MYC PROTEIN; DNA HELICASE; NUCLEAR PROTEIN; PROTEIN BINDING; SMARCA4 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

EID: 84988228120     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3170     Document Type: Article
Times cited : (98)

References (45)
  • 1
    • 34848823741 scopus 로고    scopus 로고
    • Analysis of concentration-dependent functions of PU. 1 in hematopoiesis using mouse models
    • DeKoter, R.P., Kamath, M.B. & Houston, I.B. Analysis of concentration-dependent functions of PU.1 in hematopoiesis using mouse models. Blood Cells Mol. Dis. 39, 316-320 (2007).
    • (2007) Blood Cells Mol. Dis. , vol.39 , pp. 316-320
    • Dekoter, R.P.1    Kamath, M.B.2    Houston, I.B.3
  • 2
    • 0030498975 scopus 로고    scopus 로고
    • Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
    • Wang, J.H. et al. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 5, 537-549 (1996).
    • (1996) Immunity , vol.5 , pp. 537-549
    • Wang, J.H.1
  • 3
    • 70350093398 scopus 로고    scopus 로고
    • Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development
    • Inlay, M.A. et al. Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development. Genes Dev. 23, 2376-2381 (2009).
    • (2009) Genes Dev. , vol.23 , pp. 2376-2381
    • Inlay, M.A.1
  • 4
    • 50849143861 scopus 로고    scopus 로고
    • B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells
    • Mansson, R. et al. B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells. Blood 112, 1048-1055 (2008).
    • (2008) Blood , vol.112 , pp. 1048-1055
    • Mansson, R.1
  • 5
    • 84871390259 scopus 로고    scopus 로고
    • Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate
    • Mansson, R. et al. Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate. Proc. Natl. Acad. Sci. USA 109, 21028-21033 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 21028-21033
    • Mansson, R.1
  • 6
    • 0023022625 scopus 로고
    • The c-myc oncogene perturbs B lymphocyte development in E-mu-myc transgenic mice
    • Langdon, W.Y., Harris, A.W., Cory, S. & Adams, J.M. The c-myc oncogene perturbs B lymphocyte development in E-mu-myc transgenic mice. Cell 47, 11-18 (1986).
    • (1986) Cell , vol.47 , pp. 11-18
    • Langdon, W.Y.1    Harris, A.W.2    Cory, S.3    Adams, J.M.4
  • 7
    • 79959562288 scopus 로고    scopus 로고
    • B Lymphocyte commitment program is driven by the proto-oncogene c-Myc
    • Vallespinós, M. et al. B Lymphocyte commitment program is driven by the proto-oncogene c-Myc. J. Immunol. 186, 6726-6736 (2011).
    • (2011) J. Immunol. , vol.186 , pp. 6726-6736
    • Vallespinós, M.1
  • 8
    • 84890834574 scopus 로고    scopus 로고
    • Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals
    • Heizmann, B., Kastner, P. & Chan, S. Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals. J. Exp. Med. 210, 2823-2832 (2013).
    • (2013) J. Exp. Med. , vol.210 , pp. 2823-2832
    • Heizmann, B.1    Kastner, P.2    Chan, S.3
  • 9
    • 84894504942 scopus 로고    scopus 로고
    • Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia
    • Joshi, I. et al. Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia. Nat. Immunol. 15, 294-304 (2014).
    • (2014) Nat. Immunol. , vol.15 , pp. 294-304
    • Joshi, I.1
  • 10
    • 84894413913 scopus 로고    scopus 로고
    • Stage-specific control of early B cell development by the transcription factor Ikaros
    • Schwickert, T.A. et al. Stage-specific control of early B cell development by the transcription factor Ikaros. Nat. Immunol. 15, 283-293 (2014).
    • (2014) Nat. Immunol. , vol.15 , pp. 283-293
    • Schwickert, T.A.1
  • 11
    • 33646071250 scopus 로고    scopus 로고
    • Complete sequence assembly and characterization of the C57BL/6 mouse Ig heavy chain v region
    • Johnston, C.M., Wood, A.L., Bolland, D.J. & Corcoran, A.E. Complete sequence assembly and characterization of the C57BL/6 mouse Ig heavy chain V region. J. Immunol. 176, 4221-4234 (2006).
    • (2006) J. Immunol. , vol.176 , pp. 4221-4234
    • Johnston, C.M.1    Wood, A.L.2    Bolland, D.J.3    Corcoran, A.E.4
  • 12
    • 41949121201 scopus 로고    scopus 로고
    • The 3D structure of the immunoglobulin heavy-chain locus: Implications for long-range genomic interactions
    • Jhunjhunwala, S. et al. The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions. Cell 133, 265-279 (2008).
    • (2008) Cell , vol.133 , pp. 265-279
    • Jhunjhunwala, S.1
  • 13
    • 3042693975 scopus 로고    scopus 로고
    • Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A
    • Seet, C.S., Brumbaugh, R.L. & Kee, B.L. Early B cell factor promotes B lymphopoiesis with reduced interleukin 7 responsiveness in the absence of E2A. J. Exp. Med. 199, 1689-1700 (2004).
    • (2004) J. Exp. Med. , vol.199 , pp. 1689-1700
    • Seet, C.S.1    Brumbaugh, R.L.2    Kee, B.L.3
  • 14
    • 34249035911 scopus 로고    scopus 로고
    • Yin Yang 1 is a critical regulator of B-cell development
    • Liu, H. et al. Yin Yang 1 is a critical regulator of B-cell development. Genes Dev. 21, 1179-1189 (2007).
    • (2007) Genes Dev. , vol.21 , pp. 1179-1189
    • Liu, H.1
  • 15
    • 1542343974 scopus 로고    scopus 로고
    • Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene
    • Fuxa, M. et al. Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene. Genes Dev. 18, 411-422 (2004).
    • (2004) Genes Dev. , vol.18 , pp. 411-422
    • Fuxa, M.1
  • 16
    • 84876836223 scopus 로고    scopus 로고
    • Modification of enhancer chromatin: What, how, and why?
    • Calo, E. & Wysocka, J. Modification of enhancer chromatin: what, how, and why? Mol. Cell 49, 825-837 (2013).
    • (2013) Mol. Cell , vol.49 , pp. 825-837
    • Calo, E.1    Wysocka, J.2
  • 17
    • 78650758676 scopus 로고    scopus 로고
    • Histone H3K27ac separates active from poised enhancers and predicts developmental state
    • Creyghton, M.P. et al. Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc. Natl. Acad. Sci. USA 107, 21931-21936 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 21931-21936
    • Creyghton, M.P.1
  • 18
    • 77957139539 scopus 로고    scopus 로고
    • Mediator and cohesin connect gene expression and chromatin architecture
    • Kagey, M.H. et al. Mediator and cohesin connect gene expression and chromatin architecture. Nature 467, 430-435 (2010).
    • (2010) Nature , vol.467 , pp. 430-435
    • Kagey, M.H.1
  • 19
    • 84876216563 scopus 로고    scopus 로고
    • Master transcription factors and mediator establish super-enhancers at key cell identity genes
    • Whyte, W.A. et al. Master transcription factors and mediator establish super-enhancers at key cell identity genes. Cell 153, 307-319 (2013).
    • (2013) Cell , vol.153 , pp. 307-319
    • Whyte, W.A.1
  • 20
    • 75749101495 scopus 로고    scopus 로고
    • Chromatin remodelling during development
    • Ho, L. & Crabtree, G.R. Chromatin remodelling during development. Nature 463, 474-484 (2010).
    • (2010) Nature , vol.463 , pp. 474-484
    • Ho, L.1    Crabtree, G.R.2
  • 21
    • 0141705373 scopus 로고    scopus 로고
    • Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4
    • Morshead, K.B., Ciccone, D.N., Taverna, S.D., Allis, C.D. & Oettinger, M.A. Antigen receptor loci poised for V(D)J rearrangement are broadly associated with BRG1 and flanked by peaks of histone H3 dimethylated at lysine 4. Proc. Natl. Acad. Sci. USA 100, 11577-11582 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 11577-11582
    • Morshead, K.B.1    Ciccone, D.N.2    Taverna, S.D.3    Allis, C.D.4    Oettinger, M.A.5
  • 22
    • 68149179271 scopus 로고    scopus 로고
    • Cutting edge: SWI/SNF mediates antisense Igh transcription and locus-wide accessibility in B cell precursors
    • Osipovich, O.A., Subrahmanyam, R., Pierce, S., Sen, R. & Oltz, E.M. Cutting edge: SWI/SNF mediates antisense Igh transcription and locus-wide accessibility in B cell precursors. J. Immunol. 183, 1509-1513 (2009).
    • (2009) J. Immunol. , vol.183 , pp. 1509-1513
    • Osipovich, O.A.1    Subrahmanyam, R.2    Pierce, S.3    Sen, R.4    Oltz, E.M.5
  • 23
    • 67650445510 scopus 로고    scopus 로고
    • Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5
    • Gao, H. et al. Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5. Proc. Natl. Acad. Sci. USA 106, 11258-11263 (2009).
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 11258-11263
    • Gao, H.1
  • 24
    • 84860347851 scopus 로고    scopus 로고
    • The SWI/SNF-like BAF complex is essential for early B cell development
    • Choi, J. et al. The SWI/SNF-like BAF complex is essential for early B cell development. J. Immunol. 188, 3791-3803 (2012).
    • (2012) J. Immunol. , vol.188 , pp. 3791-3803
    • Choi, J.1
  • 25
    • 27744534349 scopus 로고    scopus 로고
    • Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation
    • Indra, A.K. et al. Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation. Development 132, 4533-4544 (2005).
    • (2005) Development , vol.132 , pp. 4533-4544
    • Indra, A.K.1
  • 26
    • 77949956058 scopus 로고    scopus 로고
    • Fate mapping reveals separate origins of T cells and myeloid lineages in the thymus
    • Schlenner, S.M. et al. Fate mapping reveals separate origins of T cells and myeloid lineages in the thymus. Immunity 32, 426-436 (2010).
    • (2010) Immunity , vol.32 , pp. 426-436
    • Schlenner, S.M.1
  • 27
    • 0033103374 scopus 로고    scopus 로고
    • Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes
    • Kim, J. et al. Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes. Immunity 10, 345-355 (1999).
    • (1999) Immunity , vol.10 , pp. 345-355
    • Kim, J.1
  • 28
    • 0033805828 scopus 로고    scopus 로고
    • An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells
    • O'Neill, D.W. et al. An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells. Mol. Cell. Biol. 20, 7572-7582 (2000).
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7572-7582
    • O'neill, D.W.1
  • 29
    • 1642311876 scopus 로고    scopus 로고
    • Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent
    • Ikawa, T., Kawamoto, H., Wright, L.Y. & Murre, C. Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent. Immunity 20, 349-360 (2004).
    • (2004) Immunity , vol.20 , pp. 349-360
    • Ikawa, T.1    Kawamoto, H.2    Wright, L.Y.3    Murre, C.4
  • 30
    • 77953763449 scopus 로고    scopus 로고
    • A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate
    • Lin, Y.C. et al. A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate. Nat. Immunol. 11, 635-643 (2010).
    • (2010) Nat. Immunol. , vol.11 , pp. 635-643
    • Lin, Y.C.1
  • 31
    • 84888877924 scopus 로고    scopus 로고
    • Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
    • Buenrostro, J.D., Giresi, P.G., Zaba, L.C., Chang, H.Y. & Greenleaf, W.J. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. Nat. Methods 10, 1213-1218 (2013).
    • (2013) Nat. Methods , vol.10 , pp. 1213-1218
    • Buenrostro, J.D.1    Giresi, P.G.2    Zaba, L.C.3    Chang, H.Y.4    Greenleaf, W.J.5
  • 32
    • 1142285361 scopus 로고    scopus 로고
    • Regulation of E2A gene expression in B-lymphocyte development
    • Zhuang, Y., Jackson, A., Pan, L., Shen, K. & Dai, M. Regulation of E2A gene expression in B-lymphocyte development. Mol. Immunol. 40, 1165-1177 (2004).
    • (2004) Mol. Immunol. , vol.40 , pp. 1165-1177
    • Zhuang, Y.1    Jackson, A.2    Pan, L.3    Shen, K.4    Dai, M.5
  • 33
    • 84862778059 scopus 로고    scopus 로고
    • Spatial organization of the mouse genome and its role in recurrent chromosomal translocations
    • Zhang, Y. et al. Spatial organization of the mouse genome and its role in recurrent chromosomal translocations. Cell 148, 908-921 (2012).
    • (2012) Cell , vol.148 , pp. 908-921
    • Zhang, Y.1
  • 34
    • 84869502375 scopus 로고    scopus 로고
    • Global changes in the nuclear positioning of genes and intra-and interdomain genomic interactions that orchestrate B cell fate
    • Lin, Y.C. et al. Global changes in the nuclear positioning of genes and intra-and interdomain genomic interactions that orchestrate B cell fate. Nat. Immunol. 13, 1196-1204 (2012).
    • (2012) Nat. Immunol. , vol.13 , pp. 1196-1204
    • Lin, Y.C.1
  • 35
    • 79951737927 scopus 로고    scopus 로고
    • The distal VH gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells
    • Ebert, A. et al. The distal VH gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells. Immunity 34, 175-187 (2011).
    • (2011) Immunity , vol.34 , pp. 175-187
    • Ebert, A.1
  • 36
    • 84882616986 scopus 로고    scopus 로고
    • Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire
    • Medvedovic, J. et al. Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire. Immunity 39, 229-244 (2013).
    • (2013) Immunity , vol.39 , pp. 229-244
    • Medvedovic, J.1
  • 37
    • 84890717859 scopus 로고    scopus 로고
    • Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation
    • Shi, J. et al. Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation. Genes Dev. 27, 2648-2662 (2013).
    • (2013) Genes Dev. , vol.27 , pp. 2648-2662
    • Shi, J.1
  • 38
    • 77949920493 scopus 로고    scopus 로고
    • MYC as a regulator of ribosome biogenesis and protein synthesis
    • van Riggelen, J., Yetil, A. & Felsher, D.W. MYC as a regulator of ribosome biogenesis and protein synthesis. Nat. Rev. Cancer 10, 301-309 (2010).
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 301-309
    • Van Riggelen, J.1    Yetil, A.2    Felsher, D.W.3
  • 39
    • 77952567987 scopus 로고    scopus 로고
    • Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
    • Heinz, S. et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 38, 576-589 (2010).
    • (2010) Mol. Cell , vol.38 , pp. 576-589
    • Heinz, S.1
  • 40
    • 84907419194 scopus 로고    scopus 로고
    • Chromatin state dynamics during blood formation
    • Lara-Astiaso, D. et al. Chromatin state dynamics during blood formation. Science 345, 943-949 (2014).
    • (2014) Science , vol.345 , pp. 943-949
    • Lara-Astiaso, D.1
  • 41
    • 0037512311 scopus 로고    scopus 로고
    • Distinct strategies to make nucleosomal DNA accessible
    • Fan, H.Y., He, X., Kingston, R.E. & Narlikar, G.J. Distinct strategies to make nucleosomal DNA accessible. Mol. Cell 11, 1311-1322 (2003).
    • (2003) Mol. Cell , vol.11 , pp. 1311-1322
    • Fan, H.Y.1    He, X.2    Kingston, R.E.3    Narlikar, G.J.4
  • 42
    • 32044439558 scopus 로고    scopus 로고
    • Selective and antagonistic functions of SWI/SNF and Mi-2beta nucleosome remodeling complexes during an inflammatory response
    • Ramirez-Carrozzi, V.R. et al. Selective and antagonistic functions of SWI/SNF and Mi-2beta nucleosome remodeling complexes during an inflammatory response. Genes Dev. 20, 282-296 (2006).
    • (2006) Genes Dev. , vol.20 , pp. 282-296
    • Ramirez-Carrozzi, V.R.1
  • 43
    • 84862102070 scopus 로고    scopus 로고
    • E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin κ locus
    • Sakamoto, S. et al. E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin κ locus. J. Immunol. 188, 5547-5560 (2012).
    • (2012) J. Immunol. , vol.188 , pp. 5547-5560
    • Sakamoto, S.1
  • 44
    • 84897502156 scopus 로고    scopus 로고
    • Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance
    • Buscarlet, M. et al. Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance. Blood 123, 1720-1728 (2014).
    • (2014) Blood , vol.123 , pp. 1720-1728
    • Buscarlet, M.1
  • 45
    • 84893685103 scopus 로고    scopus 로고
    • Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling
    • Clark, M.R., Mandal, M., Ochiai, K. & Singh, H. Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling. Nat. Rev. Immunol. 14, 69-80 (2014).
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 69-80
    • Clark, M.R.1    Mandal, M.2    Ochiai, K.3    Singh, H.4


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