메뉴 건너뛰기




Volumn 24, Issue 9, 2017, Pages 572-577

Gene therapy research in Asia

Author keywords

[No Author keywords available]

Indexed keywords

ASIA; CANCER GENE THERAPY; CARDIOVASCULAR DISEASE; CHINA; CLINICAL TRIAL (TOPIC); GENE THERAPY; GENE VECTOR; HUMAN; INFECTION; MONOGENIC DISORDER; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; REVIEW; MEDICAL RESEARCH; STATISTICS AND NUMERICAL DATA;

EID: 85032486259     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2017.62     Document Type: Review
Times cited : (16)

References (77)
  • 1
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptormodified T cells in chronic lymphoid leukemia
    • Porter DL, Levine BL, Kalos M, Bagg A, June CH. Chimeric antigen receptormodified T cells in chronic lymphoid leukemia. N Engl J Med 2011; 365: 725-733.
    • (2011) N Engl J Med , vol.365 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3    Bagg, A.4    June, C.H.5
  • 2
    • 84947743247 scopus 로고    scopus 로고
    • Gene therapy for cancer: Regulatory considerations for approval
    • Husain SR, Han J, Au P, Shannon K, Puri RK. Gene therapy for cancer: regulatory considerations for approval. Cancer Gene Ther 2015; 22: 554-563.
    • (2015) Cancer Gene Ther , vol.22 , pp. 554-563
    • Husain, S.R.1    Han, J.2    Au, P.3    Shannon, K.4    Puri, R.K.5
  • 3
    • 84895487305 scopus 로고    scopus 로고
    • Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV
    • Tebas P, Stein D, Tang WW, Frank I, Wang SQ, Lee G et al. Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV. N Engl J Med 2014; 370: 901-910.
    • (2014) N Engl J Med , vol.370 , pp. 901-910
    • Tebas, P.1    Stein, D.2    Tang, W.W.3    Frank, I.4    Wang, S.Q.5    Lee, G.6
  • 6
    • 76249131912 scopus 로고    scopus 로고
    • Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease
    • Stein S, Ott MG, Schultze-Strasser S, Jauch A, Burwinkel B, Kinner A et al. Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease. Nat Med 2010; 16: 198-204.
    • (2010) Nat Med , vol.16 , pp. 198-204
    • Stein, S.1    Ott, M.G.2    Schultze-Strasser, S.3    Jauch, A.4    Burwinkel, B.5    Kinner, A.6
  • 7
    • 0142089747 scopus 로고    scopus 로고
    • Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
    • Raper SE, Chirmule N, Lee FS, Wivel NA, Bagg A, Gao GP et al. Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Mol Genet Metab 2003; 80: 148-158.
    • (2003) Mol Genet Metab , vol.80 , pp. 148-158
    • Raper, S.E.1    Chirmule, N.2    Lee, F.S.3    Wivel, N.A.4    Bagg, A.5    Gao, G.P.6
  • 9
    • 1342289322 scopus 로고    scopus 로고
    • Activation of the T-cell oncogene LMO2 after gene therapy for X-linked severe combined immunodeficiency
    • McCormack MP, Rabbitts TH. Activation of the T-cell oncogene LMO2 after gene therapy for X-linked severe combined immunodeficiency. N Engl J Med 2004; 350: 913-922.
    • (2004) N Engl J Med , vol.350 , pp. 913-922
    • McCormack, M.P.1    Rabbitts, T.H.2
  • 11
    • 70449337791 scopus 로고    scopus 로고
    • Medicine A comeback for gene therapy
    • Naldini L. Medicine. A comeback for gene therapy. Science (New York, NY) 2009; 326: 805-806.
    • (2009) Science (New York, NY) , vol.326 , pp. 805-806
    • Naldini, L.1
  • 12
    • 84890814629 scopus 로고    scopus 로고
    • Breakthrough of the year 2013 Cancer immunotherapy
    • Couzin-Frankel J. Breakthrough of the year 2013. Cancer immunotherapy. Science (New York, NY) 2013; 342: 1432-1433.
    • (2013) Science (New York, NY) , vol.342 , pp. 1432-1433
    • Couzin-Frankel, J.1
  • 13
    • 24944454988 scopus 로고    scopus 로고
    • Current status of gendicine in China: Recombinant human Ad-p53 agent for treatment of cancers
    • Peng Z. Current status of gendicine in China: recombinant human Ad-p53 agent for treatment of cancers. Hum Gene Ther 2005; 16: 1016-1027.
    • (2005) Hum Gene Ther , vol.16 , pp. 1016-1027
    • Peng, Z.1
  • 14
    • 84863543350 scopus 로고    scopus 로고
    • Clinical development of oncolytic viruses in China
    • Liang M. Clinical development of oncolytic viruses in China. Curr Pharm Biotechnol 2012; 13: 1852-1857.
    • (2012) Curr Pharm Biotechnol , vol.13 , pp. 1852-1857
    • Liang, M.1
  • 15
    • 84866899464 scopus 로고    scopus 로고
    • Endgame: Glybera finally recommended for approval as the first gene therapy drug in the European union
    • Yla-Herttuala S. Endgame: glybera finally recommended for approval as the first gene therapy drug in the European union. Mol Ther 2012; 20: 1831-1832.
    • (2012) Mol Ther , vol.20 , pp. 1831-1832
    • Yla-Herttuala, S.1
  • 17
    • 85006216313 scopus 로고    scopus 로고
    • Investor outlook: Rising from the ashes; GSK's European approval of strimvelis for ADA-SCID
    • Schimmer J, Breazzano S. Investor outlook: rising from the ashes; GSK's European approval of strimvelis for ADA-SCID. Hum Gene Ther Clin Dev 2016; 27: 57-61.
    • (2016) Hum Gene Ther Clin Dev , vol.27 , pp. 57-61
    • Schimmer, J.1    Breazzano, S.2
  • 18
    • 85007203250 scopus 로고    scopus 로고
    • Motor neuron disease: Nusinersen potentially effective in SMA
    • Adams L. Motor neuron disease: Nusinersen potentially effective in SMA. Nat Rev Neurol 2017; 13: 66.
    • (2017) Nat Rev Neurol , vol.13 , pp. 66
    • Adams, L.1
  • 19
    • 85006321439 scopus 로고    scopus 로고
    • Treatment of infantile-onset spinal muscular atrophy with nusinersen: A phase 2, open-label, dose-escalation study
    • Finkel RS, Chiriboga CA, Vajsar J, Day JW, Montes J, De Vivo DC et al. Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study. Lancet (Lond, Engl) 2016; 388: 3017-3026.
    • (2016) Lancet (Lond, Engl) , vol.388 , pp. 3017-3026
    • Finkel, R.S.1    Chiriboga, C.A.2    Vajsar, J.3    Day, J.W.4    Montes, J.5    De Vivo, D.C.6
  • 20
    • 84982136632 scopus 로고    scopus 로고
    • Chinese scientists to pioneer first human CRISPR trial
    • Cyranoski D. Chinese scientists to pioneer first human CRISPR trial. Nature 2016; 535: 476-477.
    • (2016) Nature , vol.535 , pp. 476-477
    • Cyranoski, D.1
  • 23
    • 84896098750 scopus 로고    scopus 로고
    • Mutant p53 in cancer: New functions and therapeutic opportunities
    • Muller PA, Vousden KH. Mutant p53 in cancer: new functions and therapeutic opportunities. Cancer Cell 2014; 25: 304-317.
    • (2014) Cancer Cell , vol.25 , pp. 304-317
    • Muller, P.A.1    Vousden, K.H.2
  • 24
    • 84923116483 scopus 로고    scopus 로고
    • Key points of basic theories and clinical practice in rAd-p53 (Gendicine ) gene therapy for solid malignant tumors
    • Li Y, Li B, Li CJ, Li LJ. Key points of basic theories and clinical practice in rAd-p53 (Gendicine ) gene therapy for solid malignant tumors. Expert Opin Biol Ther 2015; 15: 437-454.
    • (2015) Expert Opin Biol Ther , vol.15 , pp. 437-454
    • Li, Y.1    Li, B.2    Li, C.J.3    Li, L.J.4
  • 25
    • 22244479672 scopus 로고    scopus 로고
    • Heat shock phenocopies E1B-55 K late functions and selectively sensitizes refractory tumor cells to ONYX-015 oncolytic viral therapy
    • O'Shea CC, Soria C, Bagus B, McCormick F. Heat shock phenocopies E1B-55 K late functions and selectively sensitizes refractory tumor cells to ONYX-015 oncolytic viral therapy. Cancer Cell 2005; 8: 61-74.
    • (2005) Cancer Cell , vol.8 , pp. 61-74
    • O'Shea, C.C.1    Soria, C.2    Bagus, B.3    McCormick, F.4
  • 26
    • 19944363519 scopus 로고    scopus 로고
    • Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity
    • O'Shea CC, Johnson L, Bagus B, Choi S, Nicholas C, Shen A et al. Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity. Cancer Cell 2004; 6: 611-623.
    • (2004) Cancer Cell , vol.6 , pp. 611-623
    • O'Shea, C.C.1    Johnson, L.2    Bagus, B.3    Choi, S.4    Nicholas, C.5    Shen, A.6
  • 27
  • 28
    • 84960285027 scopus 로고    scopus 로고
    • Progress and problems with the use of suicide genes for targeted cancer therapy
    • Karjoo Z, Chen X, Hatefi A. Progress and problems with the use of suicide genes for targeted cancer therapy. Adv Drug Deliv Rev 2016; 99 (Pt A): 113-128.
    • (2016) Adv Drug Deliv Rev , vol.99 , pp. 113-128
    • Karjoo, Z.1    Chen, X.2    Hatefi, A.3
  • 29
    • 35348903899 scopus 로고    scopus 로고
    • Adjuvant adenovirus-mediated delivery of herpes simplex virus thymidine kinase administration improves outcome of liver transplantation in patients with advanced hepatocellular carcinoma
    • Li N, Zhou J, Weng D, Zhang C, Li L, Wang B et al. Adjuvant adenovirus-mediated delivery of herpes simplex virus thymidine kinase administration improves outcome of liver transplantation in patients with advanced hepatocellular carcinoma. Clin Cancer Res 2007; 13: 5847-5854.
    • (2007) Clin Cancer Res , vol.13 , pp. 5847-5854
    • Li, N.1    Zhou, J.2    Weng, D.3    Zhang, C.4    Li, L.5    Wang, B.6
  • 30
    • 68949197421 scopus 로고    scopus 로고
    • Phase i and biodistribution study of recombinant adenovirus vector-mediated herpes simplex virus thymidine kinase gene and ganciclovir administration in patients with head and neck cancer and other malignant tumors
    • Xu F, Li S, Li XL, Guo Y, Zou BY, Xu R et al. Phase I and biodistribution study of recombinant adenovirus vector-mediated herpes simplex virus thymidine kinase gene and ganciclovir administration in patients with head and neck cancer and other malignant tumors. Cancer Gene Ther 2009; 16: 723-730.
    • (2009) Cancer Gene Ther , vol.16 , pp. 723-730
    • Xu, F.1    Li, S.2    Li, X.L.3    Guo, Y.4    Zou, B.Y.5    Xu, R.6
  • 31
    • 84957989697 scopus 로고    scopus 로고
    • Adenovirus-mediated delivery of herpes simplex virus thymidine kinase administration improves outcome of recurrent high-grade glioma
    • Ji N, Weng D, Liu C, Gu Z, Chen S, Guo Y et al. Adenovirus-mediated delivery of herpes simplex virus thymidine kinase administration improves outcome of recurrent high-grade glioma. Oncotarget 2016; 7: 4369-4378.
    • (2016) Oncotarget , vol.7 , pp. 4369-4378
    • Ji, N.1    Weng, D.2    Liu, C.3    Gu, Z.4    Chen, S.5    Guo, Y.6
  • 32
    • 84879790467 scopus 로고    scopus 로고
    • Antitumor effects of radioiodine labeled KH901 on nude mice bearing hepatoma
    • Mi Y, Li Y, Long Y. [Antitumor effects of radioiodine labeled KH901 on nude mice bearing hepatoma]. J Biomed Eng 2010; 27: 389-394.
    • (2010) J Biomed Eng , vol.27 , pp. 389-394
    • Mi, Y.1    Li, Y.2    Long, Y.3
  • 33
    • 77951029861 scopus 로고    scopus 로고
    • Imaging of radioiodine-labeled KH901, a tumor-specific oncolytic recombinant adenovirus, in nude mice with human hepatocellular carcinoma
    • Mi YX, Li YC, Long YH. Imaging of radioiodine-labeled KH901, a tumor-specific oncolytic recombinant adenovirus, in nude mice with human hepatocellular carcinoma. Nucl Med Commun 2010; 31: 405-410.
    • (2010) Nucl Med Commun , vol.31 , pp. 405-410
    • Mi, Y.X.1    Li, Y.C.2    Long, Y.H.3
  • 34
    • 66149098502 scopus 로고    scopus 로고
    • A phase i study of KH901, a conditionally replicating granulocyte-macrophage colony-stimulating factor: Armed oncolytic adenovirus for the treatment of head and neck cancers
    • Chang J, Zhao X, Wu X, Guo Y, Guo H, Cao J et al. A phase I study of KH901, a conditionally replicating granulocyte-macrophage colony-stimulating factor: armed oncolytic adenovirus for the treatment of head and neck cancers. Cancer Biol Ther 2009; 8: 676-682.
    • (2009) Cancer Biol Ther , vol.8 , pp. 676-682
    • Chang, J.1    Zhao, X.2    Wu, X.3    Guo, Y.4    Guo, H.5    Cao, J.6
  • 35
    • 85016090043 scopus 로고    scopus 로고
    • Study on the application effect of Once Vex (GM)(-)(CSF) and adriamycin in the interventional therapy of malignant tumor in clinical curative effect
    • Gao YD, Chen GL, Guo PD, Yang XL. [Study on the application effect of Once Vex (GM)(-)(CSF) and adriamycin in the interventional therapy of malignant tumor in clinical curative effect]. Zhonghua Yi Xue Za Zhi 2016; 96: 2173-2175.
    • (2016) Zhonghua Yi Xue Za Zhi , vol.96 , pp. 2173-2175
    • Gao, Y.D.1    Chen, G.L.2    Guo, P.D.3    Yang, X.L.4
  • 36
    • 80053028199 scopus 로고    scopus 로고
    • Gene therapy with recombinant adenovirus encoding endostatin encapsulated in cationic liposome in coxsackievirus and adenovirus receptor-deficient colon carcinoma murine models
    • Wang L, Yao B, Li Q, Mei K, Xu JR, Li HX et al. Gene therapy with recombinant adenovirus encoding endostatin encapsulated in cationic liposome in coxsackievirus and adenovirus receptor-deficient colon carcinoma murine models. Hum Gene Ther 2011; 22: 1061-1069.
    • (2011) Hum Gene Ther , vol.22 , pp. 1061-1069
    • Wang, L.1    Yao, B.2    Li, Q.3    Mei, K.4    Xu, J.R.5    Li, H.X.6
  • 37
    • 84902177306 scopus 로고    scopus 로고
    • Multicenter randomized phase 2 clinical trial of a recombinant human endostatin adenovirus in patients with advanced head and neck carcinoma
    • Ye W, Liu R, Pan C, Jiang W, Zhang L, Guan Z et al. Multicenter randomized phase 2 clinical trial of a recombinant human endostatin adenovirus in patients with advanced head and neck carcinoma. Mol Ther 2014; 22: 1221-1229.
    • (2014) Mol Ther , vol.22 , pp. 1221-1229
    • Ye, W.1    Liu, R.2    Pan, C.3    Jiang, W.4    Zhang, L.5    Guan, Z.6
  • 38
    • 84925607772 scopus 로고    scopus 로고
    • Adoptive cellular therapy: A race to the finish line
    • June CH, Riddell SR, Schumacher TN. Adoptive cellular therapy: a race to the finish line. Sci Transl Med 2015; 7: 280ps7.
    • (2015) Sci Transl Med , vol.7 , pp. 280ps7
    • June, C.H.1    Riddell, S.R.2    Schumacher, T.N.3
  • 39
    • 85007288271 scopus 로고    scopus 로고
    • Regression of glioblastoma after chimeric antigen receptor T-cell therapy
    • Brown CE, Alizadeh D, Starr R, Weng L, Wagner JR, Naranjo A et al. Regression of glioblastoma after chimeric antigen receptor T-cell therapy. N Engl J Med 2016; 375: 2561-2569.
    • (2016) N Engl J Med , vol.375 , pp. 2561-2569
    • Brown, C.E.1    Alizadeh, D.2    Starr, R.3    Weng, L.4    Wagner, J.R.5    Naranjo, A.6
  • 41
    • 84978886867 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells for the treatment of solid tumors: Defining the challenges and next steps
    • Beatty GL, O'Hara M. Chimeric antigen receptor-modified T cells for the treatment of solid tumors: defining the challenges and next steps. Pharmacol Ther 2016; 166: 30-39.
    • (2016) Pharmacol Ther , vol.166 , pp. 30-39
    • Beatty, G.L.1    O'Hara, M.2
  • 42
    • 84920693049 scopus 로고    scopus 로고
    • Treatment of CD33-directed chimeric antigen receptor-modified T cells in one patient with relapsed and refractory acute myeloid leukemia
    • Wang QS, Wang Y, Lv HY, Han QW, Fan H, Guo B et al. Treatment of CD33-directed chimeric antigen receptor-modified T cells in one patient with relapsed and refractory acute myeloid leukemia. Mol Ther 2015; 23: 184-191.
    • (2015) Mol Ther , vol.23 , pp. 184-191
    • Wang, Q.S.1    Wang, Y.2    Lv, H.Y.3    Han, Q.W.4    Fan, H.5    Guo, B.6
  • 43
    • 84941758827 scopus 로고    scopus 로고
    • Tolerance and efficacy of autologous or donor-derived T cells expressing CD19 chimeric antigen receptors in adult B-ALL with extramedullary leukemia
    • Dai H, Zhang W, Li X, Han Q, Guo Y, Zhang Y et al. Tolerance and efficacy of autologous or donor-derived T cells expressing CD19 chimeric antigen receptors in adult B-ALL with extramedullary leukemia. Oncoimmunology 2015; 4: e1027469.
    • (2015) Oncoimmunology , vol.4 , pp. e1027469
    • Dai, H.1    Zhang, W.2    Li, X.3    Han, Q.4    Guo, Y.5    Zhang, Y.6
  • 44
    • 84908299844 scopus 로고    scopus 로고
    • Effective response and delayed toxicities of refractory advanced diffuse large B-cell lymphoma treated by CD20-directed chimeric antigen receptor-modified T cells
    • Wang Y, Zhang WY, Han QW, Liu Y, Dai HR, Guo YL et al. Effective response and delayed toxicities of refractory advanced diffuse large B-cell lymphoma treated by CD20-directed chimeric antigen receptor-modified T cells. Clin Immunol 2014; 155: 160-175.
    • (2014) Clin Immunol , vol.155 , pp. 160-175
    • Wang, Y.1    Zhang, W.Y.2    Han, Q.W.3    Liu, Y.4    Dai, H.R.5    Guo, Y.L.6
  • 45
    • 85008425546 scopus 로고    scopus 로고
    • Cocktail treatment with EGFRspecific and CD133-specific chimeric antigen receptor-modified T cells in a patient with advanced cholangiocarcinoma
    • Feng KC, Guo YL, Liu Y, Dai HR, Wang Y, Lv HY et al. Cocktail treatment with EGFRspecific and CD133-specific chimeric antigen receptor-modified T cells in a patient with advanced cholangiocarcinoma. J Hematol Oncol 2017; 10: 4.
    • (2017) J Hematol Oncol , vol.10 , pp. 4
    • Feng, K.C.1    Guo, Y.L.2    Liu, Y.3    Dai, H.R.4    Wang, Y.5    Lv, H.Y.6
  • 46
    • 85018795014 scopus 로고    scopus 로고
    • Phase i escalating-dose trial of CAR-T therapy targeting CEA+ metastatic colorectal cancers
    • Zhang C, Wang Z, Yang Z, Wang M, Li S, Li Y et al. Phase I escalating-dose trial of CAR-T therapy targeting CEA+ metastatic colorectal cancers. Mol Ther 2017; 25: 1248-1258.
    • (2017) Mol Ther , vol.25 , pp. 1248-1258
    • Zhang, C.1    Wang, Z.2    Yang, Z.3    Wang, M.4    Li, S.5    Li, Y.6
  • 47
  • 48
    • 84902095353 scopus 로고    scopus 로고
    • Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
    • Yin H, Xue W, Chen S, Bogorad RL, Benedetti E, Grompe M et al. Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype. Nat Biotechnol 2014; 32: 551-553.
    • (2014) Nat Biotechnol , vol.32 , pp. 551-553
    • Yin, H.1    Xue, W.2    Chen, S.3    Bogorad, R.L.4    Benedetti, E.5    Grompe, M.6
  • 49
    • 84875230671 scopus 로고    scopus 로고
    • DVC1-0101 to treat peripheral arterial disease: A Phase I/IIa open-label dose-escalation clinical trial
    • Yonemitsu Y, Matsumoto T, Itoh H, Okazaki J, Uchiyama M, Yoshida K et al. DVC1-0101 to treat peripheral arterial disease: a Phase I/IIa open-label dose-escalation clinical trial. Mol Ther 2013; 21: 707-714.
    • (2013) Mol Ther , vol.21 , pp. 707-714
    • Yonemitsu, Y.1    Matsumoto, T.2    Itoh, H.3    Okazaki, J.4    Uchiyama, M.5    Yoshida, K.6
  • 50
    • 84978700997 scopus 로고    scopus 로고
    • Improved quality of life in patients with no-option critical limb ischemia undergoing gene therapy with DVC1-0101
    • Matsumoto T, Tanaka M, Yoshiya K, Yoshiga R, Matsubara Y, Horiuchi-Yoshida K et al. Improved quality of life in patients with no-option critical limb ischemia undergoing gene therapy with DVC1-0101. Sci Rep 2016; 6: 30035.
    • (2016) Sci Rep , vol.6 , pp. 30035
    • Matsumoto, T.1    Tanaka, M.2    Yoshiya, K.3    Yoshiga, R.4    Matsubara, Y.5    Horiuchi-Yoshida, K.6
  • 51
    • 85001875191 scopus 로고    scopus 로고
    • Necroptosis induced by Ad-HGF activates endogenous C-Kit+ cardiac stem cells and promotes cardiomyocyte proliferation and angiogenesis in the infarcted aged heart
    • Liu J, Wu P, Wang H, Wang Y, Du Y, Cheng W et al. Necroptosis induced by Ad-HGF activates endogenous C-Kit+ cardiac stem cells and promotes cardiomyocyte proliferation and angiogenesis in the infarcted aged heart. Cell Physiol Biochem 2016; 40: 847-860.
    • (2016) Cell Physiol Biochem , vol.40 , pp. 847-860
    • Liu, J.1    Wu, P.2    Wang, H.3    Wang, Y.4    Du, Y.5    Cheng, W.6
  • 52
    • 67651099104 scopus 로고    scopus 로고
    • Phase i clinical trial on intracoronary administration of Ad-hHGF treating severe coronary artery disease
    • Yang ZJ, Zhang YR, Chen B, Zhang SL, Jia EZ, Wang LS et al. Phase I clinical trial on intracoronary administration of Ad-hHGF treating severe coronary artery disease. Mol Biol Rep 2009; 36: 1323-1329.
    • (2009) Mol Biol Rep , vol.36 , pp. 1323-1329
    • Yang, Z.J.1    Zhang, Y.R.2    Chen, B.3    Zhang, S.L.4    Jia, E.Z.5    Wang, L.S.6
  • 53
    • 84998890554 scopus 로고    scopus 로고
    • Ad-HGF improves the cardiac remodeling of rat following myocardial infarction by upregulating autophagy and necroptosis and inhibiting apoptosis
    • Liu J, Wu P, Wang Y, Du Y, N A, Liu S et al. Ad-HGF improves the cardiac remodeling of rat following myocardial infarction by upregulating autophagy and necroptosis and inhibiting apoptosis. Am J Transl Res 2016; 8: 4605-4627.
    • (2016) Am J Transl Res , vol.8 , pp. 4605-4627
    • Liu, J.1    Wu, P.2    Wang, Y.3    Du, Y.4    Liu, S.5
  • 54
    • 77953173235 scopus 로고    scopus 로고
    • Improvement of heart function in postinfarct heart failure swine models after hepatocyte growth factor gene transfer: Comparison of low-, medium-and high-dose groups
    • Yang ZJ, Chen B, Sheng Z, Zhang DG, Jia EZ, Wang W et al. Improvement of heart function in postinfarct heart failure swine models after hepatocyte growth factor gene transfer: comparison of low-, medium-and high-dose groups. Mol Biol Rep 2010; 37: 2075-2081.
    • (2010) Mol Biol Rep , vol.37 , pp. 2075-2081
    • Yang, Z.J.1    Chen, B.2    Sheng, Z.3    Zhang, D.G.4    Jia, E.Z.5    Wang, W.6
  • 55
    • 0031975088 scopus 로고    scopus 로고
    • Successful peripheral T-lymphocyte-directed gene transfer for a patient with severe combined immune deficiency caused by adenosine deaminase deficiency
    • Onodera M, Ariga T, Kawamura N, Kobayashi I, Ohtsu M, Yamada M et al. Successful peripheral T-lymphocyte-directed gene transfer for a patient with severe combined immune deficiency caused by adenosine deaminase deficiency. Blood 1998; 91: 30-36.
    • (1998) Blood , vol.91 , pp. 30-36
    • Onodera, M.1    Ariga, T.2    Kawamura, N.3    Kobayashi, I.4    Ohtsu, M.5    Yamada, M.6
  • 56
    • 0030275393 scopus 로고    scopus 로고
    • Implantation of autologous skin fibroblast genetically modified to secrete clotting factor IX partially corrects the hemorrhagic tendencies in two hemophilia B patients
    • Qiu X, Lu D, Zhou J, Wang J, Yang J, Meng P et al. Implantation of autologous skin fibroblast genetically modified to secrete clotting factor IX partially corrects the hemorrhagic tendencies in two hemophilia B patients. Chinese Med J 1996; 109: 832-839.
    • (1996) Chinese Med J , vol.109 , pp. 832-839
    • Qiu, X.1    Lu, D.2    Zhou, J.3    Wang, J.4    Yang, J.5    Meng, P.6
  • 57
    • 84988521082 scopus 로고    scopus 로고
    • Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: An ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial
    • Sessa M, Lorioli L, Fumagalli F, Acquati S, Redaelli D, Baldoli C et al. Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial. Lancet (Lond, Engl) 2016; 388: 476-487.
    • (2016) Lancet (Lond, Engl) , vol.388 , pp. 476-487
    • Sessa, M.1    Lorioli, L.2    Fumagalli, F.3    Acquati, S.4    Redaelli, D.5    Baldoli, C.6
  • 60
    • 85007425309 scopus 로고    scopus 로고
    • Gene therapy: A promising approach for neuroprotection in Parkinson's disease?
    • Valdes P, Schneider BL. Gene therapy: a promising approach for neuroprotection in Parkinson's disease? Front Neuroanat 2016; 10: 123.
    • (2016) Front Neuroanat , vol.10 , pp. 123
    • Valdes, P.1    Schneider, B.L.2
  • 62
    • 84897076939 scopus 로고    scopus 로고
    • Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: A dose escalation, open-label, phase 1/2 trial
    • Palfi S, Gurruchaga JM, Ralph GS, Lepetit H, Lavisse S, Buttery PC et al. Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial. Lancet (Lond, Engl) 2014; 383: 1138-1146.
    • (2014) Lancet (Lond, Engl) , vol.383 , pp. 1138-1146
    • Palfi, S.1    Gurruchaga, J.M.2    Ralph, G.S.3    Lepetit, H.4    Lavisse, S.5    Buttery, P.C.6
  • 64
    • 85002632505 scopus 로고    scopus 로고
    • Gene therapy to cure HIV: Where to from here?
    • Johnston R. Gene therapy to cure HIV: where to from here? AIDS Patient Care STDs 2016; 30: 531-533.
    • (2016) AIDS Patient Care STDs , vol.30 , pp. 531-533
    • Johnston, R.1
  • 65
    • 61849131130 scopus 로고    scopus 로고
    • Increased in vivo immunological potency of HB-110, a novel therapeutic HBV DNA vaccine, by electroporation
    • Kim CY, Kang ES, Kim SB, Kim HE, Choi JH, Lee DS et al. Increased in vivo immunological potency of HB-110, a novel therapeutic HBV DNA vaccine, by electroporation. Exp Mol Med 2008; 40: 669-676.
    • (2008) Exp Mol Med , vol.40 , pp. 669-676
    • Kim, C.Y.1    Kang, E.S.2    Kim, S.B.3    Kim, H.E.4    Choi, J.H.5    Lee, D.S.6
  • 66
    • 84922699091 scopus 로고    scopus 로고
    • Safety and immunogenicity of therapeutic DNA vaccine with antiviral drug in chronic HBV patients and its immunogenicity in mice
    • Yoon SK, Seo YB, Im SJ, Bae SH, Song MJ, You CR et al. Safety and immunogenicity of therapeutic DNA vaccine with antiviral drug in chronic HBV patients and its immunogenicity in mice. Liver Int 2015; 35: 805-815.
    • (2015) Liver Int , vol.35 , pp. 805-815
    • Yoon, S.K.1    Seo, Y.B.2    Im, S.J.3    Bae, S.H.4    Song, M.J.5    You, C.R.6
  • 68
    • 84944339068 scopus 로고    scopus 로고
    • Gene therapy returns to centre stage
    • Naldini L. Gene therapy returns to centre stage. Nature 2015; 526: 351-360.
    • (2015) Nature , vol.526 , pp. 351-360
    • Naldini, L.1
  • 70
    • 84961291537 scopus 로고    scopus 로고
    • Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy
    • Long C, Amoasii L, Mireault AA, McAnally JR, Li H, Sanchez-Ortiz E et al. Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy. Science (New York, NY) 2016; 351: 400-403.
    • (2016) Science (New York, NY) , vol.351 , pp. 400-403
    • Long, C.1    Amoasii, L.2    Mireault, A.A.3    McAnally, J.R.4    Li, H.5    Sanchez-Ortiz, E.6
  • 72
    • 84960422519 scopus 로고    scopus 로고
    • CRISPR/Cas9-mediated somatic correction of a novel coagulator factor IX gene mutation ameliorates hemophilia in mouse
    • Guan Y, Ma Y, Li Q, Sun Z, Ma L, Wu L et al. CRISPR/Cas9-mediated somatic correction of a novel coagulator factor IX gene mutation ameliorates hemophilia in mouse. EMBO Mol Med 2016; 8: 477-488.
    • (2016) EMBO Mol Med , vol.8 , pp. 477-488
    • Guan, Y.1    Ma, Y.2    Li, Q.3    Sun, Z.4    Ma, L.5    Wu, L.6
  • 73
    • 85032485286 scopus 로고    scopus 로고
    • Sciences NAoMedicine NAoNational Academies of Sciences E, Medicine. Human Genome Editing: Science, Ethics, and Governance. The National Academies Press: Washington, DC, 2017
    • Sciences NAoMedicine NAoNational Academies of Sciences E, Medicine. Human Genome Editing: Science, Ethics, and Governance. The National Academies Press: Washington, DC, 2017.
  • 74
    • 84884162833 scopus 로고    scopus 로고
    • Broadening the indications for hematopoietic stem cell genetic therapies
    • Williams DA. Broadening the indications for hematopoietic stem cell genetic therapies. Cell Stem Cell 2013; 13: 263-264.
    • (2013) Cell Stem Cell , vol.13 , pp. 263-264
    • Williams, D.A.1
  • 76
    • 84928475324 scopus 로고    scopus 로고
    • Clinical applications of gene therapy for primary immunodeficiencies
    • Cicalese MP, Aiuti A. Clinical applications of gene therapy for primary immunodeficiencies. Hum Gene Ther 2015; 26: 210-219.
    • (2015) Hum Gene Ther , vol.26 , pp. 210-219
    • Cicalese, M.P.1    Aiuti, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.