A comeback for gene therapy

Science

Volumn 326, Issue 5954, 2009, Pages 805-806

  Naldini, Luigi ^a  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LENTIVIRUS VECTOR; MYELIN; RETROVIRUS VECTOR; ABC TRANSPORTER; ABCD1 PROTEIN, HUMAN;

DISEASE TREATMENT; GENETIC ENGINEERING; NERVOUS SYSTEM DISORDER; VIRUS;

ABCD1 GENE; ADRENOLEUKODYSTROPHY; BONE MARROW; CARCINOGENESIS; CELL TRANSFER; CHILDHOOD DISEASE; CLINICAL TRIAL; DEGENERATIVE DISEASE; DEMYELINATING DISEASE; ENGRAFTMENT; GENE; GENE EXPRESSION; GENE MUTATION; GENE THERAPY; GENE TRANSFER; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; LENTIVIRINAE; LEUKEMIA; MICROGLIA; MUTAGENESIS; OLIGODENDROGLIA; PRIORITY JOURNAL; PROGENY; SHORT SURVEY; VIRAL GENE DELIVERY SYSTEM; X CHROMOSOME LINKED DISORDER; AUTOTRANSPLANTATION; CHILD; DISEASE COURSE; GENE VECTOR; GENETIC TRANSDUCTION; GENETICS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN IMMUNODEFICIENCY VIRUS 1; MALE; NOTE; PHYSIOLOGY; VIROLOGY; VIRUS DNA CELL DNA INTERACTION;

LENTIVIRUS;

ADRENOLEUKODYSTROPHY; ATP-BINDING CASSETTE TRANSPORTERS; CHILD; DISEASE PROGRESSION; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HIV-1; HUMANS; MALE; TRANSDUCTION, GENETIC; TRANSPLANTATION, AUTOLOGOUS; VIRUS INTEGRATION;

EID: 70449337791     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1181937     Document Type: Short Survey

References (18)

1. A. Aiuti et al., N. Engl. J. Med. 360,447 (2009).
2. A. Fischer, M. Cavazzana-Calvo, Lancet 371,2044 (2008).
3. J.W. Miller, N. Engl. J. Med. 358, 2282 (2008).
4. N. Cartier et al., Science 326,818 (2009).
5. L. Naldini et al., Science 272, 263 (1996).
6. N. Uchida et al., Proc. Natl. Acad. Sei. U.S.A. 95,11939 (1998).
7. H. Miyoshi, K. A. Smith, D. E. Mosier, I. M. Verma, B. E. Torbett, Science 283, 682 (1999).
8. S. S. Case et al., Proc. Natl. Acad. Sei. U.S.A. 96, 2988 (1999).
9. F. Mazurier, O. I. Gan, J. L. McKenzie, M. Doedens, J. E. Dick, Blood 103, 545 (2004).
10. G. D. Trobridge et al., Blood 111, 5537 (2008).
11. Y. J. Kim et al., Blood 113, 5434 (2009).
12. P. Aubourg et al., N. Engl. J. Med. 322,1860 (1990).
13. F. Bushman et al., Nat. Rev. Microbiol. 3,848 (2005).
14. C. Cattoglio et al., Blood 110,1770 (2007).
15. E. Montini et al., J. Clin. Invest. 119,964 (2009).
16. U. Modlich et al., Mol. Ther. 10.1038/mt.2009.179 (2009).
17. M. G. Ott et al., Nat. Med. 12,401 (2006).
18. C. Baum et al., Hum. Gene Ther. 17, 253 (2006).