메뉴 건너뛰기




Volumn 30, Issue 12, 2016, Pages 531-533

Gene therapy to cure HIV: Where to from here?

Author keywords

Cure; Gene therapy; HIV; In vivo targeting; Transduction efficiency

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CHEMOKINE RECEPTOR CCR5;

EID: 85002632505     PISSN: 10872914     EISSN: 15577449     Source Type: Journal    
DOI: 10.1089/apc.2016.0240     Document Type: Review
Times cited : (6)

References (19)
  • 1
    • 84994860400 scopus 로고    scopus 로고
    • HIV DNA set point is rapidly established in acute HIV infection and dramatically reduced by early ART
    • Ananworanich J, Chomont N, Eller LA, et al. HIV DNA set point is rapidly established in acute HIV infection and dramatically reduced by early ART. EBioMedicine 2016; 11:68-72.
    • (2016) EBioMedicine , vol.11 , pp. 68-72
    • Ananworanich, J.1    Chomont, N.2    Eller, L.A.3
  • 2
    • 84901502098 scopus 로고    scopus 로고
    • A randomized open-label study of 3- versus 5-drug combination anti-retroviral therapy in newly HIV-1-infected individuals
    • Markowitz M, Evering TH, Garmon D, et al. A randomized open-label study of 3- versus 5-drug combination anti-retroviral therapy in newly HIV-1-infected individuals. J Acquir Immune Defic Syndr 2014;66:140-147.
    • (2014) J Acquir Immune Defic Syndr , vol.66 , pp. 140-147
    • Markowitz, M.1    Evering, T.H.2    Garmon, D.3
  • 3
    • 84894046809 scopus 로고    scopus 로고
    • Intensification of a raltegravir-based regimen with maraviroc in early HIV-1 infection
    • Puertas MC, Massanella M, Llibre JM, et al. Intensification of a raltegravir-based regimen with maraviroc in early HIV-1 infection. AIDS 2014;28:325-334.
    • (2014) AIDS , vol.28 , pp. 325-334
    • Puertas, M.C.1    Massanella, M.2    Llibre, J.M.3
  • 4
    • 84978120368 scopus 로고    scopus 로고
    • International AIDS Society global scientific strategy: Towards an HIV cure 2016
    • Deeks SG, Lewin SR, Ross AL, et al. International AIDS Society global scientific strategy: Towards an HIV cure 2016. Nat Med 2016;22:839-850.
    • (2016) Nat Med , vol.22 , pp. 839-850
    • Deeks, S.G.1    Lewin, S.R.2    Ross, A.L.3
  • 5
    • 0036888919 scopus 로고    scopus 로고
    • Viral evolution during structured treatment interruptions in chronically human immunodeficiency virus-infected individuals
    • Martinez-Picado J, Frost SD, Izquierdo N, et al. Viral evolution during structured treatment interruptions in chronically human immunodeficiency virus-infected individuals. J Virol 2002;76:12344-12348.
    • (2002) J Virol , vol.76 , pp. 12344-12348
    • Martinez-Picado, J.1    Frost, S.D.2    Izquierdo, N.3
  • 6
    • 33751515147 scopus 로고    scopus 로고
    • CD4+ count-guided interruption of antiretroviral treatment
    • Strategies for Management of Antiretroviral Therapy Study Group, El-Sadr WM, Lundgren J, et al. CD4+ count-guided interruption of antiretroviral treatment. N Engl J Med 2006; 355:2283-2296.
    • (2006) N Engl J Med , vol.355 , pp. 2283-2296
    • El-Sadr, W.M.1    Lundgren, J.2
  • 7
    • 84986211938 scopus 로고    scopus 로고
    • Therapeutic vaccines and immuno-logical intervention in HIV infection: A paradigm change
    • Pantaleo G, Levy Y. Therapeutic vaccines and immuno-logical intervention in HIV infection: A paradigm change. Curr Opin HIV AIDS 2016;11:576-584.
    • (2016) Curr Opin HIV AIDS , vol.11 , pp. 576-584
    • Pantaleo, G.1    Levy, Y.2
  • 8
    • 84936874205 scopus 로고    scopus 로고
    • Expanded cytotoxic T-cell lymphocytes target the latent HIV reservoir
    • Sung JA, Lam S, Garrido C, et al. Expanded cytotoxic T-cell lymphocytes target the latent HIV reservoir. J Infect Dis 2015;212:258-263.
    • (2015) J Infect Dis , vol.212 , pp. 258-263
    • Sung, J.A.1    Lam, S.2    Garrido, C.3
  • 9
    • 85002640390 scopus 로고    scopus 로고
    • Combining cell and gene therapy in an effort to eradicate HIV
    • Wagner T. Combining cell and gene therapy in an effort to eradicate HIV. AIDS Patient Care STDs 2016;30:534-538.
    • (2016) AIDS Patient Care STDs , vol.30 , pp. 534-538
    • Wagner, T.1
  • 10
    • 85002774820 scopus 로고    scopus 로고
    • Engineering HIV-specific immunity with chimeric antigen receptors
    • Kitchen SG, Zack JA. Engineering HIV-specific immunity with chimeric antigen receptors. AIDS Patient Care STDs 2016;30:556-561.
    • (2016) AIDS Patient Care STDs , vol.30 , pp. 556-561
    • Kitchen, S.G.1    Zack, J.A.2
  • 11
    • 84928405730 scopus 로고    scopus 로고
    • Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117
    • Caskey M, Klein F, Lorenzi JC, et al. Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117. Nature 2015;522:487-491.
    • (2015) Nature , vol.522 , pp. 487-491
    • Caskey, M.1    Klein, F.2    Lorenzi, J.C.3
  • 13
    • 60549090253 scopus 로고    scopus 로고
    • Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
    • Hutter G, Nowak D, Mossner M, et al. Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N Engl J Med 2009;360:692-698.
    • (2009) N Engl J Med , vol.360 , pp. 692-698
    • Hutter, G.1    Nowak, D.2    Mossner, M.3
  • 14
    • 84878503062 scopus 로고    scopus 로고
    • Challenges in detecting HIV persistence during potentially curative interventions: A study of the Berlin patient
    • Yukl SA, Boritz E, Busch M, et al. Challenges in detecting HIV persistence during potentially curative interventions: A study of the Berlin patient. PLoS Pathog 2013;9: e1003347.
    • (2013) PLoS Pathog , vol.9 , pp. e1003347
    • Yukl, S.A.1    Boritz, E.2    Busch, M.3
  • 15
    • 85002749257 scopus 로고    scopus 로고
    • Clinical applications of genome editing to HIV cure
    • Wang CX, Cannon PM. Clinical applications of genome editing to HIV cure. AIDS Patient Care STDs 2016;30: 539-544.
    • (2016) AIDS Patient Care STDs , vol.30 , pp. 539-544
    • Wang, C.X.1    Cannon, P.M.2
  • 16
    • 85002669470 scopus 로고    scopus 로고
    • Cell-delivered entry inhibitors for HIV-1: CCR5 downregula-tion and blocking virus/membrane fusion in defending the host cell population
    • Symonds G, Bartlett JS, Kiem H-P, Tsie M, Breton L. Cell-delivered entry inhibitors for HIV-1: CCR5 downregula-tion and blocking virus/membrane fusion in defending the host cell population. AIDS Patient Care STDs 2016;30: 545-550.
    • (2016) AIDS Patient Care STDs , vol.30 , pp. 545-550
    • Symonds, G.1    Bartlett, J.S.2    Kiem, H.-P.3    Tsie, M.4    Breton, L.5
  • 17
    • 85002755328 scopus 로고    scopus 로고
    • Disruption or excision of provirus as an approach to HIV cure
    • Jerome KR. Disruption or excision of provirus as an approach to HIV cure. AIDS Patient Care STDs 2016;30:551-555.
    • (2016) AIDS Patient Care STDs , vol.30 , pp. 551-555
    • Jerome, K.R.1
  • 18
    • 84895487305 scopus 로고    scopus 로고
    • Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV
    • Tebas P, Stein D, Tang WW, et al. Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV. N Engl J Med 2014;370:901-910.
    • (2014) N Engl J Med , vol.370 , pp. 901-910
    • Tebas, P.1    Stein, D.2    Tang, W.W.3
  • 19
    • 84979860400 scopus 로고    scopus 로고
    • Viremic control and viral coreceptor usage in two HIV-1-infected persons ho-mozygous for CCR5 Delta32
    • Henrich TJ, Hanhauser E, Hu Z, et al. Viremic control and viral coreceptor usage in two HIV-1-infected persons ho-mozygous for CCR5 Delta32. AIDS 2015;29:867-876.
    • (2015) AIDS , vol.29 , pp. 867-876
    • Henrich, T.J.1    Hanhauser, E.2    Hu, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.