A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages

Cell Stem Cell

Volumn 21, Issue 3, 2017, Pages 399-410.e7

  Tchieu, Jason ^a   Zimmer, Bastian ^a   Fattahi, Faranak ^a,b   Amin, Sadaf ^b,c   Zeltner, Nadja ^a   Chen, Shuibing ^c   Studer, Lorenz ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Weill Cornell Medical Center   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

chemical screen; chemically defined Ectoderm; cortical neurons; cranial placode; directed differentiation; human pluripotent stem cells; neural crest; non neural ectoderm; TFAP2A

Indexed keywords

3 [4 METHYL 2 (2 OXO 3 INDOLINYLMETHYLIDENYL) 3 PYRROLYL]PROPIONIC ACID; 6 [4 (1 PIPERAZINYL)PHENYL] 3 (4 QUINOLINYL)PYRAZOLO[1,5 A]PYRIMIDINE; 6 [[2 [[4 (2,4 DICHLOROPHENYL) 5 (4 METHYL 1H IMIDAZOL 2 YL) 2 PYRIMIDINYL]AMINO]ETHYL]AMINO]NICOTINONITRILE; ANXA1 PROTEIN; BONE MORPHOGENETIC PROTEIN 4; ELAV LIKE PROTEIN 4; HAND1 PROTEIN; LGI1 PROTEIN; MYOD PROTEIN; NEUROGENIN 1; NR2F2 PROTEIN; PHENANTHROLINE; PROTEIN; SMYD1 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP2 ALPHA; TRANSCRIPTION FACTOR AP2 BETA; TRANSCRIPTION FACTOR HES 5; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR SIX1; TRANSCRIPTION FACTOR SOX1; TRANSCRIPTION FACTOR SOX10; TRANSCRIPTION FACTOR SOX17; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VITRONECTIN; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN 229; ZINC FINGER PROTEIN 503; BONE MORPHOGENETIC PROTEIN; PHENANTHROLINE DERIVATIVE; TFAP2A PROTEIN, HUMAN; TRANSCRIPTION FACTOR AP 2;

ARTICLE; CALCIUM BINDING; CELL ADHESION; CELL DENSITY; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; ECTODERM; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; KERATINOCYTE; MEMBRANE TRANSPORT; NEURAL CREST; NEUROECTODERM; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; UPREGULATION; WNT SIGNALING; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; METABOLISM; MOLECULAR LIBRARY; NEURAL STEM CELL; PHARMACOLOGY; SIGNAL TRANSDUCTION;

BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL LINEAGE; ECTODERM; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; NEURAL CREST; NEURAL PLATE; NEURAL STEM CELLS; PHENANTHROLINES; PLURIPOTENT STEM CELLS; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES; TRANSCRIPTION FACTOR AP-2;

EID: 85030847462     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2017.08.015     Document Type: Article

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