Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease

Nature

Volumn 531, Issue 7592, 2016, Pages 105-109

  Fattahi, Faranak ^a,b,c   Steinbeck, Julius A ^a,b   Kriks, Sonja ^a,b   Tchieu, Jason ^a,b   Zimmer, Bastian ^a,b   Kishinevsky, Sarah ^a,b,c   Zeltner, Nadja ^a,b   Mica, Yvonne ^a,b,h   El Nachef, Wael ^d   Zhao, Huiyong ^d   De Stanchina, Elisa ^d   Gershon, Michael D ^e   Grikscheit, Tracy C ^f   Chen, Shuibing ^g   Studer, Lorenz ^a,b  

^a The Center for Stem Cell Biology   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c Weill Cornell Graduate School of Biomedical Sciences   (United States)

^d Molecular Pharmacology and Chemistry Program   (United States)

^e College of Physicians and Surg ^*  (United States)

^f CHILDREN S HOSPITAL LOS ANGELES   (United States)

^g WEILL CORNELL MEDICAL COLLEGE   (United States)

^h Thermo Fisher Scientific   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROTRANSMITTER; PEPSTATIN; EDNRB PROTEIN, HUMAN; ENDOTHELIN B RECEPTOR;

CELLS AND CELL COMPONENTS; COLONIZATION; DIGESTIVE SYSTEM; DISEASE; DRUG; DRUG DEVELOPMENT; HEALTH CARE; NERVOUS SYSTEM;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CELL LINEAGE; CELL MIGRATION; CELL THERAPY; CHICK EMBRYO; COLON; ENGRAFTMENT; HIRSCHSPRUNG DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INTESTINE INNERVATION; MORTALITY; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROGENITOR CELL LINE; AGING; ANIMAL; BIOLOGICAL THERAPY; CELL LINE; CELL MOTION; CELL SEPARATION; DISEASE MODEL; DRUG DEVELOPMENT; DRUG EFFECTS; FEMALE; GASTROINTESTINAL TRACT; MALE; METABOLISM; NERVE CELL; PATHOLOGY; PROCEDURES; SIGNAL TRANSDUCTION;

MUS;

AGING; ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; CELL MOVEMENT; CELL SEPARATION; CELL- AND TISSUE-BASED THERAPY; CHICK EMBRYO; COLON; DISEASE MODELS, ANIMAL; DRUG DISCOVERY; ENTERIC NERVOUS SYSTEM; FEMALE; GASTROINTESTINAL TRACT; HIRSCHSPRUNG DISEASE; HUMANS; MALE; MICE; NEURONS; PEPSTATINS; PLURIPOTENT STEM CELLS; RECEPTOR, ENDOTHELIN B; SIGNAL TRANSDUCTION;

EID: 84960145334     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature16951     Document Type: Article

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