Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence

Experimental Gerontology

Volumn 99, Issue , 2017, Pages 35-45

  Malavolta, Marco ^a   Costarelli, Laura ^a   Giacconi, Robertina ^a   Basso, Andrea ^a   Piacenza, Francesco ^a   Pierpaoli, Elisa ^a   Provinciali, Mauro ^a   Ogo, Ogo A ^b   Ford, Dianne ^c  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c NORTHUMBRIA UNIVERSITY   (United Kingdom)

Author keywords

Aging; Cellular senescence; Labile Zn; p16; Zn homeostasis; Zn transporters

Indexed keywords

METALLOTHIONEIN; ZINC; CHELATING AGENT; ETHYLENEDIAMINE DERIVATIVE; N,N,N',N'-TETRAKIS(2-PYRIDYLMETHYL)ETHYLENEDIAMINE; ZINC SULFATE;

ARTICLE; CELL AGING; CELL CULTURE; CELL DEATH; CELL DIVISION; CELL GROWTH; CELL POPULATION; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXICITY; ENDOTHELIUM CELL; GENE; GENE EXPRESSION; GENETIC CORRELATION; GROWTH DISORDER; HOMEOSTASIS; HUMAN; HUMAN CELL; LONG TERM EXPOSURE; METALLOTHIONEIN GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SLC30A1 GENE; SLC30A10 GENE; SLC30A5 GENE; SLC39A6 GENE; VASCULAR DISEASE; ZINC DEFICIENCY; APOPTOSIS; CELL PROLIFERATION; CELL SHAPE; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC DATABASE; METABOLISM; PATHOLOGY; PRIMARY CELL CULTURE; TIME FACTOR; UMBILICAL VEIN ENDOTHELIAL CELL;

APOPTOSIS; CELL PROLIFERATION; CELL SHAPE; CELLS, CULTURED; CELLULAR SENESCENCE; CHELATING AGENTS; DATABASES, GENETIC; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ETHYLENEDIAMINES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HOMEOSTASIS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; PRIMARY CELL CULTURE; TIME FACTORS; ZINC SULFATE;

EID: 85029826616     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2017.09.006     Document Type: Article

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