A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential

Cell

Volumn 171, Issue 1, 2017, Pages 229-241.e15

  Wang, Jiaqi ^a,b   Bardelli, Marco ^c   Espinosa, Diego A ^d   Pedotti, Mattia ^c   Ng, Thiam Seng ^a,b   Bianchi, Siro ^e   Simonelli, Luca ^c   Lim, Elisa X Y ^a,b   Foglierini, Mathilde ^c   Zatta, Fabrizia ^e   Jaconi, Stefano ^e   Beltramello, Martina ^e   Cameroni, Elisabetta ^e   Fibriansah, Guntur ^a,b   Shi, Jian ^b,f   Barca, Taylor ^d   Pagani, Isabel ^g   Rubio, Alicia ^g   Broccoli, Vania ^g,h   Vicenzi, Elisa ^g   Graham, Victoria ⁱ   Pullan, Steven ⁱ   Dowall, Stuart ⁱ   Hewson, Roger ⁱ   Jurt, Simon ^j   Zerbe, Oliver ^j   Stettler, Karin ^e   Lanzavecchia, Antonio ^c   Sallusto, Federica ^c   Cavalli, Andrea ^c   Harris, Eva ^d   Lok, Shee Mei ^a,b   Varani, Luca ^c   Corti, Davide ^e   more..

^a DUKE NUS MEDICAL SCHOOL   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Switzerland)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e Humabs BioMed SA a subsidiary of Vir Biotechnology Inc ^*  (Switzerland)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^g SAN RAFFAELE HOSPITAL   (Italy)

^h CNR   (Italy)

ⁱ PUBLIC HEALTH ENGLAND   (United Kingdom)

^j UNIVERSITY OF ZURICH   (Switzerland)

more..

Author keywords

neutralizing antibody; serotherapy; Zika

Indexed keywords

BISPECIFIC ANTIBODY; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY ZKA190; UNCLASSIFIED DRUG; VIRAL PROTEIN; VIRUS E PROTEIN; EPITOPE; NEUTRALIZING ANTIBODY; VIRUS ANTIBODY; VIRUS ENVELOPE PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY ISOLATION; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL SURFACE; CONTROLLED STUDY; CROSS LINKING; CRYOELECTRON MICROSCOPY; DRUG POTENCY; EPITOPE MAPPING; FEMALE; HUMAN; IN VIVO STUDY; MALE; MORBIDITY; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN QUATERNARY STRUCTURE; VIRUS MUTATION; VIRUS STRAIN; ZIKA FEVER; ZIKA VIRUS; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; IMMUNOLOGY; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SEQUENCE ALIGNMENT; ZIKA VIRUS INFECTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; CRYOELECTRON MICROSCOPY; EPITOPES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MODELS, MOLECULAR; SEQUENCE ALIGNMENT; VIRAL ENVELOPE PROTEINS; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85029651511     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.09.002     Document Type: Article

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