-
1
-
-
0012870750
-
Generation and characterization of a novel tetravalent bispecific antibody that binds to hepatitis B virus surface antigens
-
11451417.PMID
-
Park SS, Ryu CJ, Kang YJ, Kashmiri SV, Hong HJ. Generation and characterization of a novel tetravalent bispecific antibody that binds to hepatitis B virus surface antigens. Mol Immunol 2000; 37:1123-30; PMID:11451417; https://doi.org/10.1016/S0161-5890(01)00027-X
-
(2000)
Mol Immunol
, vol.37
, pp. 1123-1130
-
-
Park, S.S.1
Ryu, C.J.2
Kang, Y.J.3
Kashmiri, S.V.4
Hong, H.J.5
-
2
-
-
84919904195
-
Combined inhibition of tumor necrosis factor alpha and interleukin-17 as a therapeutic opportunity in rheumatoid arthritis: Development and characterization of a novel bispecific antibody
-
25303306.PMID
-
Fischer JA, Hueber AJ, Wilson S, Galm M, Baum W, Kitson C, Auer J, Lorenz SH, Moelleken J, Bader M, et al. Combined inhibition of tumor necrosis factor alpha and interleukin-17 as a therapeutic opportunity in rheumatoid arthritis: Development and characterization of a novel bispecific antibody. Arthritis Rheumatol 2015; 67:51-62; PMID:25303306; https://doi.org/10.1002/art.38896
-
(2015)
Arthritis Rheumatol
, vol.67
, pp. 51-62
-
-
Fischer, J.A.1
Hueber, A.J.2
Wilson, S.3
Galm, M.4
Baum, W.5
Kitson, C.6
Auer, J.7
Lorenz, S.H.8
Moelleken, J.9
Bader, M.10
-
3
-
-
84977497581
-
A novel bispecific antibody targeting EGFR and cMet is effective against EGFR inhibitor-resistant lung tumors
-
27216193.PMID
-
Moores SL, Chiu ML, Bushey BS, Chevalier K, Luistro L, Dorn K, Brezski RJ, Haytko P, Kelly T, Wu SJ, et al. A novel bispecific antibody targeting EGFR and cMet is effective against EGFR inhibitor-resistant lung tumors. Cancer Res 2016; 76:3942-53; PMID:27216193; https://doi.org/10.1158/0008-5472.CAN-15-2833
-
(2016)
Cancer Res
, vol.76
, pp. 3942-3953
-
-
Moores, S.L.1
Chiu, M.L.2
Bushey, B.S.3
Chevalier, K.4
Luistro, L.5
Dorn, K.6
Brezski, R.J.7
Haytko, P.8
Kelly, T.9
Wu, S.J.10
-
4
-
-
67449156132
-
Bispecific T-cell engaging antibodies for cancer therapy
-
19509221.PMID
-
Baeuerle PA, Reinhardt C. Bispecific T-cell engaging antibodies for cancer therapy. Cancer Res 2009; 69:4941-4; PMID:19509221; https://doi.org/10.1158/0008-5472.CAN-09-0547
-
(2009)
Cancer Res
, vol.69
, pp. 4941-4944
-
-
Baeuerle, P.A.1
Reinhardt, C.2
-
5
-
-
84870302675
-
A bispecific antibody to factors IXa and X restores factor VIII hemostatic activity in a hemophilia A model
-
23023498.PMID
-
Kitazawa T, Igawa T, Sampei Z, Muto A, Kojima T, Soeda T, Yoshihashi K, Okuyama-Nishida Y, Saito H, Tsunoda H, et al. A bispecific antibody to factors IXa and X restores factor VIII hemostatic activity in a hemophilia A model. Nat Med 2012; 18:1570-4; PMID:23023498; https://doi.org/10.1038/nm.2942
-
(2012)
Nat Med
, vol.18
, pp. 1570-1574
-
-
Kitazawa, T.1
Igawa, T.2
Sampei, Z.3
Muto, A.4
Kojima, T.5
Soeda, T.6
Yoshihashi, K.7
Okuyama-Nishida, Y.8
Saito, H.9
Tsunoda, H.10
-
6
-
-
49649120397
-
Tumor regression in cancer patients by very low doses of a T cell-engaging antibody
-
18703743.PMID
-
Bargou R, Leo E, Zugmaier G, Klinger M, Goebeler M, Knop S, Noppeney R, Viardot A, Hess G, Schuler M, et al. Tumor regression in cancer patients by very low doses of a T cell-engaging antibody. Science 2008; 321:974-7; PMID:18703743; https://doi.org/10.1126/science.1158545
-
(2008)
Science
, vol.321
, pp. 974-977
-
-
Bargou, R.1
Leo, E.2
Zugmaier, G.3
Klinger, M.4
Goebeler, M.5
Knop, S.6
Noppeney, R.7
Viardot, A.8
Hess, G.9
Schuler, M.10
-
7
-
-
85019289859
-
Despite slow progress, bispecifics generate buzz
-
27926715.PMID
-
Sheridan C. Despite slow progress, bispecifics generate buzz. Nat Biotechnol 2016; 34:1215-7; PMID:27926715; https://doi.org/10.1038/nbt1216-1215
-
(2016)
Nat Biotechnol
, vol.34
, pp. 1215-1217
-
-
Sheridan, C.1
-
8
-
-
85011347310
-
The making of bispecific antibodies
-
28071970.PMID
-
Brinkmann U, Kontermann RE. The making of bispecific antibodies. MAbs 2017; 9:182-212; PMID:28071970; https://doi.org/10.1080/19420862.2016.1268307
-
(2017)
MAbs
, vol.9
, pp. 182-212
-
-
Brinkmann, U.1
Kontermann, R.E.2
-
9
-
-
84881460836
-
Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies
-
23831709.PMID
-
Spiess C, Merchant M, Huang A, Zheng Z, Yang NY, Peng J, Ellerman D, Shatz W, Reilly D, Yansura DG, et al. Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies. Nat Biotechnol 2013; 31:753-8; PMID:23831709; https://doi.org/10.1038/nbt.2621
-
(2013)
Nat Biotechnol
, vol.31
, pp. 753-758
-
-
Spiess, C.1
Merchant, M.2
Huang, A.3
Zheng, Z.4
Yang, N.Y.5
Peng, J.6
Ellerman, D.7
Shatz, W.8
Reilly, D.9
Yansura, D.G.10
-
10
-
-
79960592856
-
Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies
-
21690412.PMID
-
Schaefer W, Regula JT, Bähner M, Schanzer J, Croasdale R, Dürr H, Gassner C, Georges G, Kettenberger H, Imhof-Jung S, et al. Immunoglobulin domain crossover as a generic approach for the production of bispecific IgG antibodies. Proc Natl Acad Sci U S A 2011; 108:11187-92; PMID:21690412; https://doi.org/10.1073/pnas.1019002108
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 11187-11192
-
-
Schaefer, W.1
Regula, J.T.2
Bähner, M.3
Schanzer, J.4
Croasdale, R.5
Dürr, H.6
Gassner, C.7
Georges, G.8
Kettenberger, H.9
Imhof-Jung, S.10
-
11
-
-
35948977323
-
Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin
-
17934452.PMID
-
Wu C, Ying H, Grinnell C, Bryant S, Miller R, Clabbers A, Bose S, McCarthy D, Zhu RR, Santora L, et al. Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin. Nat Biotechnol 2007; 25:1290-7; PMID:17934452; https://doi.org/10.1038/nbt1345
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1290-1297
-
-
Wu, C.1
Ying, H.2
Grinnell, C.3
Bryant, S.4
Miller, R.5
Clabbers, A.6
Bose, S.7
McCarthy, D.8
Zhu, R.R.9
Santora, L.10
-
12
-
-
84926348347
-
Alternative molecular formats and therapeutic applications for bispecific antibodies
-
25637431.PMID
-
Spiess C, Zhai Q, Carter PJ. Alternative molecular formats and therapeutic applications for bispecific antibodies. Mol Immunol 2015; 67:95-106; PMID:25637431; https://doi.org/10.1016/j.molimm.2015.01.003
-
(2015)
Mol Immunol
, vol.67
, pp. 95-106
-
-
Spiess, C.1
Zhai, Q.2
Carter, P.J.3
-
15
-
-
84895153556
-
Emerging cell and cytokine targets in rheumatoid arthritis
-
24217582.PMID
-
Burmester GR, Feist E, Dörner T. Emerging cell and cytokine targets in rheumatoid arthritis. Nat Rev Rheumatol 2014; 10:77-88; PMID:24217582; https://doi.org/10.1038/nrrheum.2013.168
-
(2014)
Nat Rev Rheumatol
, vol.10
, pp. 77-88
-
-
Burmester, G.R.1
Feist, E.2
Dörner, T.3
-
16
-
-
38649119730
-
Signaling networks assembled by oncogenic EGFR and c-Met
-
18180459.PMID
-
Guo A, Villén J, Kornhauser J, Lee KA, Stokes MP, Rikova K, Possemato A, Nardone J, Innocenti G, Wetzel R, et al. Signaling networks assembled by oncogenic EGFR and c-Met. Proc Natl Acad Sci U S A 2008; 105:692-7; PMID:18180459; https://doi.org/10.1073/pnas.0707270105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 692-697
-
-
Guo, A.1
Villén, J.2
Kornhauser, J.3
Lee, K.A.4
Stokes, M.P.5
Rikova, K.6
Possemato, A.7
Nardone, J.8
Innocenti, G.9
Wetzel, R.10
-
17
-
-
73649102105
-
Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC
-
20129249.PMID
-
Turke AB, Zejnullahu K, Wu YL, Song Y, Dias-Santagata D, Lifshits E, Toschi L, Rogers A, Mok T, Sequist L, et al. Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC. Cancer Cell 2010; 17:77-88; PMID:20129249; https://doi.org/10.1016/j.ccr.2009.11.022
-
(2010)
Cancer Cell
, vol.17
, pp. 77-88
-
-
Turke, A.B.1
Zejnullahu, K.2
Wu, Y.L.3
Song, Y.4
Dias-Santagata, D.5
Lifshits, E.6
Toschi, L.7
Rogers, A.8
Mok, T.9
Sequist, L.10
-
20
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao W, Miller VA, Politi KA, Riely GJ, Somwar R, Zakowski MF, Kris MG, Varmus H. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2005; 2:0225-35; PMID:15737014; https://dx.doi/10.1371/journal.pmed.0020073
-
(2005)
PLoS Med
, vol.2
, pp. 0225-235
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
Riely, G.J.4
Somwar, R.5
Zakowski, M.F.6
Kris, M.G.7
Varmus, H.8
-
21
-
-
21144439000
-
Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib
-
15897464.PMID
-
Kwak EL, Sordella R, Bell DW, Godin-Heymann N, Okimoto RA, Brannigan BW, Harris PL, Driscoll DR, Fidias P, Lynch TJ, et al. Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib. Proc Natl Acad Sci U S A 2005; 102:7665-70; PMID:15897464; https://doi.org/10.1073/pnas.0502860102
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 7665-7670
-
-
Kwak, E.L.1
Sordella, R.2
Bell, D.W.3
Godin-Heymann, N.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Driscoll, D.R.8
Fidias, P.9
Lynch, T.J.10
-
22
-
-
84950989868
-
Bispecific antibodies and their applications
-
26692321.PMID
-
Fan G, Wang Z, Hao M, Li J. Bispecific antibodies and their applications. J Hematol Oncol 2015; 8:130; PMID:26692321; https://doi.org/10.1186/s13045-015-0227-0
-
(2015)
J Hematol Oncol
, vol.8
, pp. 130
-
-
Fan, G.1
Wang, Z.2
Hao, M.3
Li, J.4
-
23
-
-
84954316938
-
A bispecific antibody targeting CD47 and CD20 selectively binds and eliminates dual antigen expressing lymphoma cells
-
26083076.PMID
-
Piccione EC, Juarez S, Liu J, Tseng S, Ryan CE, Narayanan C, Wang L, Weiskopf K, Majeti R. A bispecific antibody targeting CD47 and CD20 selectively binds and eliminates dual antigen expressing lymphoma cells. MAbs 2015; 7:946-56; PMID:26083076; https://doi.org/10.1080/19420862.2015.1062192
-
(2015)
MAbs
, vol.7
, pp. 946-956
-
-
Piccione, E.C.1
Juarez, S.2
Liu, J.3
Tseng, S.4
Ryan, C.E.5
Narayanan, C.6
Wang, L.7
Weiskopf, K.8
Majeti, R.9
-
24
-
-
68449086890
-
Immunotherapy of lymphoma and leukemia with T-cell engaging BiTE antibody blinatumomab
-
19455460.PMID
-
Nagorsen D, Bargou R, Ruttinger D, Kufer P, Baeuerle PA, Zugmaier G. Immunotherapy of lymphoma and leukemia with T-cell engaging BiTE antibody blinatumomab. Leuk Lymphoma 2009; 50:886-91; PMID:19455460; https://doi.org/10.1080/10428190902943077
-
(2009)
Leuk Lymphoma
, vol.50
, pp. 886-891
-
-
Nagorsen, D.1
Bargou, R.2
Ruttinger, D.3
Kufer, P.4
Baeuerle, P.A.5
Zugmaier, G.6
-
25
-
-
84988696751
-
A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses
-
27608667.PMID
-
Wec AZ, Nyakatura EK, Herbert AS, Howell KA, Holtsberg FW, Bakken RR, Mittler E, Christin JR, Shulenin S, Jangra RK, et al. A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses. Science 2016; 354:350-4; PMID:27608667; https://doi.org/10.1126/science.aag3267
-
(2016)
Science
, vol.354
, pp. 350-354
-
-
Wec, A.Z.1
Nyakatura, E.K.2
Herbert, A.S.3
Howell, K.A.4
Holtsberg, F.W.5
Bakken, R.R.6
Mittler, E.7
Christin, J.R.8
Shulenin, S.9
Jangra, R.K.10
-
26
-
-
84975270914
-
Bispecific Anti-HIV-1 antibodies with enhanced breadth and potency
-
27315478.PMID
-
Bournazos S, Gazumyan A, Seaman MS, Nussenzweig MC, Ravetch J V. Bispecific Anti-HIV-1 antibodies with enhanced breadth and potency. Cell 2016; 165:1609-20; PMID:27315478; https://doi.org/10.1016/j.cell.2016.04.050
-
(2016)
Cell
, vol.165
, pp. 1609-1620
-
-
Bournazos, S.1
Gazumyan, A.2
Seaman, M.S.3
Nussenzweig, M.C.4
Ravetch, V.5
-
27
-
-
84945176688
-
Fab-based bispecific antibody formats with robust biophysical properties and biological activity
-
25774965.PMID
-
Wu X, Sereno AJ, Huang F, Lewis SM, Lieu RL, Weldon C, Torres C, Fine C, Batt MA, Jonathan R, et al. Fab-based bispecific antibody formats with robust biophysical properties and biological activity. MAbs 2015; 862:470-82; PMID:25774965; https://doi.org/10.1080/19420862.2015.1022694
-
(2015)
MAbs
, vol.862
, pp. 470-482
-
-
Wu, X.1
Sereno, A.J.2
Huang, F.3
Lewis, S.M.4
Lieu, R.L.5
Weldon, C.6
Torres, C.7
Fine, C.8
Batt, M.A.9
Jonathan, R.10
-
28
-
-
84962622376
-
Design and validation of a novel generic platform for the production of tetravalent IgG1-like bispecific antibodies
-
26921308.PMID
-
Golay J, Choblet S, Iwaszkiewicz J, Cérutti P, Ozil A, Loisel S, Pugnière M, Ubiali G, Zoete V, Michielin O, et al. Design and validation of a novel generic platform for the production of tetravalent IgG1-like bispecific antibodies. J Immunol 2016; 196:3199-211; PMID:26921308; https://doi.org/10.4049/jimmunol.1501592
-
(2016)
J Immunol
, vol.196
, pp. 3199-3211
-
-
Golay, J.1
Choblet, S.2
Iwaszkiewicz, J.3
Cérutti, P.4
Ozil, A.5
Loisel, S.6
Pugnière, M.7
Ubiali, G.8
Zoete, V.9
Michielin, O.10
-
29
-
-
4143137525
-
Effect of linker sequences between the antibody variable domains on the formation, stability and biological activity of a bispecific tandem diabody
-
15126676.PMID
-
Le Gall F, Reusch U, Little M, Kipriyanov SM. Effect of linker sequences between the antibody variable domains on the formation, stability and biological activity of a bispecific tandem diabody. Protein Eng Des Sel 2004; 17:357-66; PMID:15126676; https://doi.org/10.1093/protein/gzh039
-
(2004)
Protein Eng Des Sel
, vol.17
, pp. 357-366
-
-
Le Gall, F.1
Reusch, U.2
Little, M.3
Kipriyanov, S.M.4
-
30
-
-
84982295378
-
Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding
-
27532598.PMID
-
Davé E, Adams R, Zaccheo O, Carrington B, Compson JE, Dugdale S, Airey M, Malcolm S, Hailu H, Wild G, et al. Fab-dsFv: A bispecific antibody format with extended serum half-life through albumin binding. MAbs 2016; 8:1319-35; PMID:27532598; https://doi.org/10.1080/19420862.2016.1210747
-
(2016)
MAbs
, vol.8
, pp. 1319-1335
-
-
Davé, E.1
Adams, R.2
Zaccheo, O.3
Carrington, B.4
Compson, J.E.5
Dugdale, S.6
Airey, M.7
Malcolm, S.8
Hailu, H.9
Wild, G.10
-
31
-
-
84893859920
-
Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface
-
24463572.PMID
-
Lewis SM, Wu X, Pustilnik A, Sereno A, Huang F, Rick HL, Guntas G, Leaver-Fay A, Smith EM, Ho C, et al. Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat Biotechnol 2014; 32:191-8; PMID:24463572; https://doi.org/10.1038/nbt.2797
-
(2014)
Nat Biotechnol
, vol.32
, pp. 191-198
-
-
Lewis, S.M.1
Wu, X.2
Pustilnik, A.3
Sereno, A.4
Huang, F.5
Rick, H.L.6
Guntas, G.7
Leaver-Fay, A.8
Smith, E.M.9
Ho, C.10
-
32
-
-
77951520735
-
Molecular construction and optimization of anti-human IL-1α/β dual variable domain immunoglobulin (DVD-Ig) molecules
-
20068402.PMID
-
Wu C, Ying H, Bose S, Miller R, Medina L, Santora L, Ghayur T. Molecular construction and optimization of anti-human IL-1α/β dual variable domain immunoglobulin (DVD-Ig) molecules. MAbs 2009; 1:339-47; PMID:20068402; https://doi.org/10.4161/mabs.1.4.8755
-
(2009)
MAbs
, vol.1
, pp. 339-347
-
-
Wu, C.1
Ying, H.2
Bose, S.3
Miller, R.4
Medina, L.5
Santora, L.6
Ghayur, T.7
-
33
-
-
84876270534
-
Crystal structure of an Anti-Ang2 crossfab demonstrates complete structural and functional integrity of the variable domain
-
23613981.PMID
-
Fenn S, Schiller CB, Griese JJ, Duerr H, Imhof-Jung S, Gassner C, Moelleken J, Regula JT, Schaefer W, Thomas M, et al. Crystal structure of an Anti-Ang2 crossfab demonstrates complete structural and functional integrity of the variable domain. PLoS One 2013; 8:1-7; PMID:23613981; https://doi.org/10.1371/journal.pone.0061953
-
(2013)
PLoS One
, vol.8
, pp. 1-7
-
-
Fenn, S.1
Schiller, C.B.2
Griese, J.J.3
Duerr, H.4
Imhof-Jung, S.5
Gassner, C.6
Moelleken, J.7
Regula, J.T.8
Schaefer, W.9
Thomas, M.10
-
34
-
-
84890551686
-
A novel bispecific EGFR/Met antibody blocks tumor-promoting phenotypic effects induced by resistance to EGFR inhibition and has potent antitumor activity
-
23812422.PMID
-
Castoldi R, Ecker V, Wiehle L, Majety M, Busl-Schuller R, Asmussen M, Nopora A, Jucknischke U, Osl F, Kobold S, et al. A novel bispecific EGFR/Met antibody blocks tumor-promoting phenotypic effects induced by resistance to EGFR inhibition and has potent antitumor activity. Oncogene 2013; 32:5593-601; PMID:23812422; https://doi.org/10.1038/onc.2013.245
-
(2013)
Oncogene
, vol.32
, pp. 5593-5601
-
-
Castoldi, R.1
Ecker, V.2
Wiehle, L.3
Majety, M.4
Busl-Schuller, R.5
Asmussen, M.6
Nopora, A.7
Jucknischke, U.8
Osl, F.9
Kobold, S.10
-
35
-
-
0026466775
-
Plasticity of early endosomes
-
1478937,; PMID
-
Parton RG, Schrotz P, Bucci C, Gruenberg J. Plasticity of early endosomes. J Cell Sci 1992; 103(Pt 2):335-48; PMID:1478937
-
(1992)
J Cell Sci
, vol.103
, pp. 335-348
-
-
Parton, R.G.1
Schrotz, P.2
Bucci, C.3
Gruenberg, J.4
-
36
-
-
80053517167
-
Antibodies to cell surface proteins redirect intracellular trafficking pathways
-
21819978.PMID
-
St. Pierre CA, Leonard D, Corvera S, Kurt-Jones EA, Finberg RW. Antibodies to cell surface proteins redirect intracellular trafficking pathways. Exp Mol Pathol 2011; 91:723-32; PMID:21819978; https://doi.org/10.1016/j.yexmp.2011.05.011
-
(2011)
Exp Mol Pathol
, vol.91
, pp. 723-732
-
-
St. Pierre, C.A.1
Leonard, D.2
Corvera, S.3
Kurt-Jones, E.A.4
Finberg, R.W.5
-
37
-
-
84881058016
-
Multivalent immune complexes divert FcRn to lysosomes by exclusion from recycling sorting tubules
-
23741050.PMID
-
Weflen AW, Baier N, Tang Q-J, Van den Hof M, Blumberg RS, Lencer WI, Massol RH. Multivalent immune complexes divert FcRn to lysosomes by exclusion from recycling sorting tubules. Mol Biol Cell 2013; 24:2398-405; PMID:23741050; https://doi.org/10.1091/mbc.E13-04-0174
-
(2013)
Mol Biol Cell
, vol.24
, pp. 2398-2405
-
-
Weflen, A.W.1
Baier, N.2
Tang, Q.-J.3
Van den Hof, M.4
Blumberg, R.S.5
Lencer, W.I.6
Massol, R.H.7
-
38
-
-
27344439995
-
Control of epidermal growth factor receptor endocytosis by receptor dimerization, rather than receptor kinase activation
-
16113650.PMID
-
Wang Q, Villeneuve G, Wang Z. Control of epidermal growth factor receptor endocytosis by receptor dimerization, rather than receptor kinase activation. EMBO Rep 2005; 6:942-8; PMID:16113650; https://doi.org/10.1038/sj.embor.7400491
-
(2005)
EMBO Rep
, vol.6
, pp. 942-948
-
-
Wang, Q.1
Villeneuve, G.2
Wang, Z.3
-
39
-
-
84979224082
-
The use of CrossMAb technology for the generation of bi- and multispecific antibodies
-
27285945.PMID
-
Klein C, Schaefer W, Regula JT. The use of CrossMAb technology for the generation of bi- and multispecific antibodies. MAbs 2016; 8:1010-20; PMID:27285945; https://doi.org/10.1080/19420862.2016.1197457
-
(2016)
MAbs
, vol.8
, pp. 1010-1020
-
-
Klein, C.1
Schaefer, W.2
Regula, J.T.3
-
40
-
-
84964316543
-
Editorial overview: Special section: New concepts in antibody therapeutics: What's in store for antibody therapy?
-
27083411.PMID
-
Schuurman J, Parren PWHI. Editorial overview: Special section: New concepts in antibody therapeutics: What's in store for antibody therapy? Curr Opin Immunol 2016; 40:vii-xiii; PMID:27083411; https://doi.org/10.1016/j.coi.2016.04.001
-
(2016)
Curr Opin Immunol
, vol.40
, pp. vii-xiii
-
-
Schuurman, J.1
Parren, P.W.H.I.2
-
41
-
-
84924425633
-
Amgen's bispecific antibody puffs across finish line
-
25748895.PMID
-
Sheridan C. Amgen's bispecific antibody puffs across finish line. Nat Biotechnol 2015; 33:219-21; PMID:25748895; https://doi.org/10.1038/nbt0315-219
-
(2015)
Nat Biotechnol
, vol.33
, pp. 219-221
-
-
Sheridan, C.1
-
42
-
-
0026568359
-
Cytokine release and dynamics of leukocyte populations after CD3/TCR monoclonal antibody treatment
-
1400897.PMID
-
Zlabinger GJ, Stuhlmeier KM, Eher R, Schmaldienst S, Klauser R, Vychytil A, Watschinger B, Traindl O, Kovarik J, Pohanka E. Cytokine release and dynamics of leukocyte populations after CD3/TCR monoclonal antibody treatment. J Clin Immunol 1992; 12:170-7; PMID:1400897; https://doi.org/10.1007/BF00918085
-
(1992)
J Clin Immunol
, vol.12
, pp. 170-177
-
-
Zlabinger, G.J.1
Stuhlmeier, K.M.2
Eher, R.3
Schmaldienst, S.4
Klauser, R.5
Vychytil, A.6
Watschinger, B.7
Traindl, O.8
Kovarik, J.9
Pohanka, E.10
-
43
-
-
0025342326
-
Cytokine-related syndrome following injection of anti-CD3 monoclonal antibody: Further evidence for transient in vivo T cell activation
-
2138557.PMID
-
Ferran C, Sheehan K, Dy M, Schreiber R, Merite S, Landais P, Noel LH, Grau G, Bluestone J, Bach JF, et al. Cytokine-related syndrome following injection of anti-CD3 monoclonal antibody: Further evidence for transient in vivo T cell activation. Eur J Immunol 1990; 20:509-15; PMID:2138557; https://doi.org/10.1002/eji.1830200308
-
(1990)
Eur J Immunol
, vol.20
, pp. 509-515
-
-
Ferran, C.1
Sheehan, K.2
Dy, M.3
Schreiber, R.4
Merite, S.5
Landais, P.6
Noel, L.H.7
Grau, G.8
Bluestone, J.9
Bach, J.F.10
-
44
-
-
77950517325
-
The safety and side effects of monoclonal antibodies
-
20305665.PMID
-
Hansel TT, Kropshofer H, Singer T, Mitchell JA, George AJ. The safety and side effects of monoclonal antibodies. Nat Rev Drug Discov 2010; 9:325-38; PMID:20305665; https://doi.org/10.1038/nrd3003
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 325-338
-
-
Hansel, T.T.1
Kropshofer, H.2
Singer, T.3
Mitchell, J.A.4
George, A.J.5
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