Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch

Cell

Volumn 171, Issue 1, 2017, Pages 217-228.e13

  Oetjen, Landon K ^a   Mack, Madison R ^a   Feng, Jing ^a   Whelan, Timothy M ^a   Niu, Haixia ^a   Guo, Changxiong J ^a   Chen, Sisi ^b   Trier, Anna M ^a   Xu, Amy Z ^a   Tripathi, Shivani V ^a   Luo, Jialie ^a   Gao, Xiaofei ^a   Yang, Lihua ^a   Hamilton, Samantha L ^a   Wang, Peter L ^a   Brestoff, Jonathan R ^a   Council, M Laurin ^a   Brasington, Richard ^a   Schaffer, András ^a   Brombacher, Frank ^c   Hsieh, Chyi Song ^a   Gereau, Robert W ^a   Miller, Mark J ^a   Chen, Zhou Feng ^a   Hu, Hongzhen ^a   Davidson, Steve ^b   Liu, Qin ^a   Kim, Brian S ^a   more..

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

atopic dermatitis; IL 13; IL 4; IL 4R ; itch; JAK1; pruriceptor; pruritus; type 2 cytokines

Indexed keywords

ACETONE; ALCOHOL; CALCIPOTRIOL; CYTOKINE; ETHER; HISTAMINE; INTERLEUKIN 13; INTERLEUKIN 4 RECEPTOR ALPHA; JANUS KINASE 1; JANUS KINASE INHIBITOR; RUXOLITINIB; TOFACITINIB; WATER; INTERLEUKIN 4; JAK1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTHMA; ATOPIC DERMATITIS; CONTROLLED STUDY; COUGHING; DERMATITIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE SYSTEM; IMMUNOPATHOGENESIS; IMMUNOSUPPRESSIVE TREATMENT; INFECTIOUS AGENT; MALE; MOUSE; NERVE CELL STIMULATION; NERVOUS SYSTEM; NEWBORN; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; PRURITUS; SCRATCHING; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SKIN SENSATION; SOMATOSENSORY SYSTEM; TARGET CELL; ANIMAL; C57BL MOUSE; IMMUNOLOGY; METABOLISM; PATHOLOGY; SKIN DISEASE; SPINAL GANGLION;

ANIMALS; GANGLIA, SPINAL; HUMANS; INTERLEUKIN-13; INTERLEUKIN-4; JANUS KINASE 1; MICE; MICE, INBRED C57BL; PRURITUS; SENSORY RECEPTOR CELLS; SIGNAL TRANSDUCTION; SKIN DISEASES;

EID: 85029621074     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.08.006     Document Type: Article

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