Enhanced nonpeptidergic intraepidermal fiber density and an expanded subset of chloroquine-responsive trigeminal neurons in a mouse model of dry skin itch

Journal of Pain

Volumn 16, Issue 4, 2015, Pages 346-356

  Valtcheva, Manouela V ^a,b   Samineni, Vijay K ^a   Golden, Judith P ^a   Gereau, Robert W ^a   Davidson, Steve ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

Author keywords

epidermis; GDNF family receptor 3 (GFRa3); glial cellderived neurotrophic factor (GDNF); hyperinnervation; Pruritus; Ret; xerosis

Indexed keywords

ACETONE; CALCITONIN GENE RELATED PEPTIDE; CHLOROQUINE; ETHER; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR RECEPTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR RECEPTOR ALPHA3; UNCLASSIFIED DRUG; WATER; CALCIUM; ENHANCED GREEN FLUORESCENT PROTEIN; GFRA3 PROTEIN, MOUSE; GREEN FLUORESCENT PROTEIN; PROTEIN RET; RET PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEEK; COMPARATIVE STUDY; CONTROLLED STUDY; DRY SKIN; EXCITABILITY; EXPERIMENT; FORELIMB; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE FIBER; NONHUMAN; NONPEPTIDERGIC FIBER; PATCH CLAMP TECHNIQUE; PRIMARY CULTURE; PRURITUS; SCRATCHING; SENSORY NERVE CELL; SKIN ELECTROPHYSIOLOGY; SKIN NERVE; SPINAL CORD DORSAL HORN; TRIGEMINAL NERVE; TRIGEMINUS GANGLION; WHOLE CELL PATCH CLAMP; 129 MOUSE; ANIMAL; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; FACE; GENETICS; INNERVATION; METABOLISM; NERVE CELL; NEUROANATOMICAL TRACT TRACING; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SKIN; TRANSGENIC MOUSE;

ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; CALCIUM; CELLS, CULTURED; CHLOROQUINE; DISEASE MODELS, ANIMAL; FACE; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS; GREEN FLUORESCENT PROTEINS; IMMUNOHISTOCHEMISTRY; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, TRANSGENIC; NEUROANATOMICAL TRACT-TRACING TECHNIQUES; NEURONS; PATCH-CLAMP TECHNIQUES; PROTO-ONCOGENE PROTEINS C-RET; PRURITUS; SKIN; TRIGEMINAL GANGLION;

EID: 84926385337     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2015.01.005     Document Type: Article

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