Chronic urticaria: Pathogenesis and treatment

Journal of Allergy and Clinical Immunology

Volumn 114, Issue 3, 2004, Pages 465-474

  Kaplan, Allen P ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

anaphylaxis; autoimmune; Chronic urticaria; hives; skin

Indexed keywords

ANTIHISTAMINIC AGENT; CD4 ANTIGEN; CELL ADHESION MOLECULE; CETIRIZINE; CHEMOKINE; COLCHICINE; COMPLEMENT COMPONENT C5A; CORTICOSTEROID; CYCLOSPORIN; CYTOKINE; DAPSONE; DIPHENHYDRAMINE; FEXOFENADINE; HISTAMINE; HISTAMINE H2 RECEPTOR ANTAGONIST; HYDROXYCHLOROQUINE; HYDROXYZINE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E RECEPTOR; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; LEUKOTRIENE RECEPTOR BLOCKING AGENT; SALAZOSULFAPYRIDINE; STEROID; THYROID ANTIBODY;

ALPHA CHAIN; ANGIONEUROTIC EDEMA; AUTOIMMUNE DISEASE; BASOPHIL; BLOOD PRESSURE MONITORING; CELL INFILTRATION; CHRONIC URTICARIA; COMPLEMENT ACTIVATION; CREATININE BLOOD LEVEL; DISEASE SEVERITY; EOSINOPHIL; HISTOLOGY; HUMAN; IDIOPATHIC DISEASE; LYMPHOCYTE; MONOCYTE; NEUTROPHIL; PRIORITY JOURNAL; REVIEW; SEDATION; SIDE EFFECT; TH1 CELL; TH2 CELL; UREA NITROGEN BLOOD LEVEL; URINALYSIS;

AUTOANTIBODIES; AUTOIMMUNE DISEASES; CHRONIC DISEASE; CYCLOSPORINE; HISTAMINE H1 ANTAGONISTS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; STEROIDS; URTICARIA;

EID: 4444379725     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2004.02.049     Document Type: Review

References (58)

1. Kaplan A.P. Urticaria and angioedema. Adkinson N.F. Jr., Yunginger J.W., Busse W.W., Bochner B.S., Holgate S.T., Simons F.E.R. Allergy: principles and practice. 2003;1537-1558 Mosby, Philadelphia
2. Greaves M. Chronic urticaria. J Allergy Clin Immunol. 105:2000;664-672
3. DiCampli C., Gasbarrini A., Nucera E., Franceschi F., Ojetti V., Sanz Torre E., et al. Beneficial effects of Helicobacter pylori eradication on chronic idiopathic urticaria. Dig Dis Sci. 43:1998;1226-1229
4. Wedi B., Wagner S., Werfel T., Manns M.P., Kapp A. Prevalence of Helicobacter pylori associated gastritis in chronic urticaria. Int Arch Allergy Immunol. 116:1998;288-294
5. Liutu M., Kalimo K., Uksila J., Kalimo H. Etiological aspects of chronic urticaria. Int J Dermatol. 37:1998;515-519
6. Becker H., Meyer M., Paul E. Remission ration of chronic urticaria: "spontaneous" healing as result of eradication of Helicobacter pylori? Hautarzt. 49:1998;907-911
7. Vasecchi R., Pigatto P. Chronic urticaria and Helicobacter pylori. Acta Derm Venereol. 78:1998;440-442
8. Schuyder B., Helbling A., Pichler W.J. Chronic idiopathic urticaria: natural cause and association with H. pylori infection. Int Arch Allergy Immunol. 119:1999;60-63
9. Hidvegi B., Gonzales-Cabello R., Temesvari E., Szentmihalyi A., Nagy E., Fekete B., et al. The effect of heat-inactivated Helicobacter pylori in the blastogenic response of peripheral blood mononuclear cells of patients with chronic urticaria. Int Arch Allergy Immunol. 126:2001;167-172
10. Leznoff A., Josse R.G., Denberg J., Dolovich J. Association of chronic urticaria and angioedema with thyroid autoimmunity. Arch Dermatol. 119:1983;636-640
11. Leznoff A., Sussman F.L. Syndrome of idiopathic chronic urticaria and angioedema with thyroid autoimmunity: a study of 90 patients. J Allergy Clin Immunol. 84:1989;66-71
12. Kaplan A.P., Finn A. Autoimmunity and the etiology of chronic urticaria. Can J Allergy Clin Immunol. 4:1999;286-292
13. Kikuchi Y., Fann T., Kaplan A.P. Antithyroid antibodies in chronic urticaria and angioedema. J Allergy Clin Immunol. 112:2003;218
14. Gruber B.L., Baeza M., Marchese M., Agnella V., Kaplan A.P. Prevalence and functional role of anti-IgE autoantibodies in urticaria syndromes. J Invest Dermatol. 90:1988;213-217
15. Grattan C.E.H., Wallington T.B., Wurin R.P., Kennedy C.T.C., Bradfield J.W. A serological mediator in chronic idiopathic urticaria. A clinical, immunological, and histological evaluation. Br J Dermatol. 114:1986;583-590
16. Grattan C.E.H., Hamon C.G.B., Cowan M.A., Leeming R.J. Preliminary identification of a low molecular weight serological mediator in chronic idiopathic urticaria. Br J Dermatol. 119:1998;179-184
17. Hide M., Francis D.M., Grattan C.E.H., Hakimi J., Kochan J.P., Greaves M.W. Autoantibodies against the high affinity IgE receptor as a cause of histamine release in chronic urticaria. N Engl J Med. 328:1993;1599-1604
18. Grattan C.E.H., Francis D.M., Hide M., Greaves M.W. Detection of circulating histamine releasing autoantibodies with functional properties of anti-IgE in chronic urticaria. Clin Exp Allergy. 21:1992;695-704
19. Fiebiger E., Maurer D., Holub H., Reininger B., Hartmann G., Woisetschlager M., et al. Serum IgG autoantibodies directed against the a-chain of FceRI; a selection marker and pathogenetic factor for a distinct subset of chronic urticaria patients? J Clin Invest. 96:1995;2606-2612
20. Zweiman B., Valenzano M., Atkins P.C., Tanus T., Getsy J.A. Characteristics of histamine-releasing activity in the sera of patients with chronic idiopathic urticaria. J Allergy Clin Immunol. 98:1996;89-98
21. Tong L.J., Balakrishnan G., Kochan J.P., Kinet J.P., Kaplan A.P. Assessment of autoimmunity in patients with chronic urticaria. J Allergy Clin Immunol. 99:1997;461-465
22. Ferrer M., Kinet J.P., Kaplan A. Comparative studies of functional and binding assays for IgG anti-Fc (epsilon) RI alpha (alpha subunit) in chronic urticaria. J Allergy Clin Immunol. 101:1998;672-676
23. Kikuchi Y., Kaplan A.P. Mechanisms of autoimmune activation of basophils in chronic urticaria. J Allergy Clin Immunol. 107:2001;1056-1062
24. Ferrer M., Luguin E., Kaplan A.P. IL3 effect on basophil histamine release upon stimulation with chronic urticaria sera. Allergy. 58:2003;802-807
25. Ferrer M., Luguin E., Sanchez-Iborrola A., Moreno C., Sanz M.L., Kaplan A.P. Secretion of cytokines, histamine, and leukotrienes in chronic urticaria. Int Arch Allergy Immunol. 129:2002;254-260
26. Wedi B., Novacovic V., Koerner M., Kapp A. Chronic urticaria serum induces histamine release, leukotrienes production, and basophil CD63 surface expression - inhibitory effects of anti-inflammatory drugs. J Allergy Clin Immunol. 105:2000;552-560
27. Niimi N., Francis D.M., Kermani F., Odonnell B.F., Hide M., Kobzablack A., et al. Dermal mast cell activation by autoantibody against the high affinity IgE receptor in chronic urticaria. J Invest Dermatol. 106:1996;1001-1006
28. Ferrer M., Nakazawa K., Kaplan A.P. Complement dependence of histamine release in chronic urticaria. J Allergy Clin Immunol. 104:1999;169-172
29. Fiebiger E., Hammerschmid F., Stingl G., Maurer D. Anti-fcepsilon RIalpha autoantibodies in autoimmune-mediated disorders. Identification of a structure-function relationship. J Clin Invest. 101:1998;243-251
30. Horn M.P., Pachlopnik J.M., Vogel M., Dahinden M., Wurm F., Stadler B.M., et al. Conditional autoimmunity mediated by human natural anti FcεRIα antibodies. FASEB J. 15:2001;2268-2274
31. Pachlopnik J.M., Horn M.P., Fux M., Dahinden M., Mandallaz M., Schneeberger D., et al. Natural anti FcεRIα antibodies may interfere with diagnostic tests for chronic urticaria. J Autoimmun. 22:2004;43-51
32. Horn M.P., Gerster T., Ochensberger B., Derer T., Kricck F., Jouvin M.H., Kinet J.P., et al. Human anti-FceRIα auto-antibodies isolated from healthy donors cross react with tetanus toxoid. Eur J Immunol. 29:1999;1139-1148
33. Kikuchi Y., Kaplan A.P. A role for C5a in augmenting IgG-dependent histamine release from basophils in chronic urticaria. J Allergy Clin Immunol. 109:2002;114-118
34. Natbony S.F., Phillips M.E., Elias J.M., Godfrey H.P., Kaplan A.P. Histologic studies of chronic idiopathic urticaria. J Allergy Clin Immunol. 71:1983;117-183
35. Elias J., Boss C., Kaplan A.P. Studies of the cellular infiltrate of chronic idiopathic urticaria: prominence of T lymphocytes, monocytes, and mast cells. J Allergy Clin Immunol. 78:1986;914-918
36. Haas N., Toppe E., Henz B.M. Microscopic morphology of different types of urticaria. Arch Dermatol. 134:1998;41-46
37. Sabroe R.A., Poon E., Orchard G.E., Lane D., Francis D.M., Barr R.M., et al. Cutaneous inflammatory cell infiltrate in chronic idiopathic urticaria: comparison of patients with and without anti-Fc-epsilon RI or anti-IgE autoantibodies. J Allergy Clin Immunol. 103:1999;484-493
38. Peters M.S., Schroeter A.L., Kephart G.M., Gleich G.J. Localization of eosinophil granule major basic protein in chronic urticaria. J Invest Dermatol. 81:1983;39-43
39. Gratten C.E.H., Boon A.P., Eady R.A.J., Winklemann R.K. The pathology of the autologous serum skin test response in chronic urticaria resembles IgE-mediated late-phase reactions. Int Arch Allergy Appl Immunol. 93:1990;198-204
40. Haas N., Schadendort D., Henz B.M. Differential endothelial adhesion molecule expression in early and late whealing reactions. Int Arch Allergy Immunol. 115:1998;210-214
41. Lee K.H., Kim J.Y., Kang D.S., Choi Y.J., Lee W.J., Ro J.Y. Increased expression of endothelial cell adhesion molecules due to mediator release from human foreskin mast cells stimulated by autoantibodies in chronic urticaria sera. J Invest Dermatol. 118:2002;658-663
42. Ying S., Robinson D.S., Meng Q., Barata L.T., McEuen A.R., Buckley M.G., et al. C-C chemokines in allergen-induced late-phase cutaneous responses in atopic subjects: association of eotaxin with early 6-hour eosinophils, and eotaxin-2 and MCP-4 with the later 24-hour tissue eosinophilia, and relationship to basophils and other C-C chemokines (MCP-3 and RANTES). J Immunol. 163:1999;3976-3984
43. Sabroe R.A., Fiebiger E., Francis D.M., Maurer D., Seed P.T., Gratten C.E.H., et al. Classification of anti FcεRI and anti-IgE autoantibodies in chronic urticaria and correlation with disease activity. J Allergy Clin Immunol. 40:2002;492-499
44. Kern F., Lichtenstein L.M. Defective histamine release in chronic urticaria. J Clin Invest. 57:1976;1369-1377
45. Sabroe R.A., Francis D.M., Barr R.M., Black A.K., Greaves M.W. Anti-FceRI autoantibodies and basophil histamine releasability in chronic idiopathic urticaria. J Allergy Clin Immunol. 102:1998;651-658
46. Grattan C.E., Walpole D., Francis D.M., Niimi N., Dootson G., Edler S., et al. Flow cytometric analysis of basophil numbers in chronic urticaria: basopenia is related to serum histamine releasing activity. Clin Exp Allergy. 27:1997;1417-1424
47. Confino-Cohen R., Aharoni D., Goldberg A., Gurevitch I., Buchs A., Weiss M., Weissgarten J., et al. Evidence for aberrant regulation of the P21 Ras pathway in PBMCCs of patients with chronic urticaria. J Allergy Clin Immunol. 109:2002;349-356
48. Kaplan A.P. Chronic urticaria and angioedema. N Engl J Med. 346:2002;175-179
49. Torbi E., Blant A., Kessel A., Golan T.D. Low-dose cyclosporine A is the treatment of severe chronic idiopathic urticaria. Allergy. 52:1997;312-316
50. Fradin M.S., Ellis C.N., Goldfarb M.T., Vourhees J.J. Oral cyclosporine for severe chronic idiopathic urticaria and angioedema. J Am Acad Dermatol. 25:1991;1065-1067
51. Grattan C.E.H., O'Donnell B.F., Francis D.M., et al. Randomized double-blind study of cyclosporine in chronic idiopathic urticaria. Br J Dermatol. 143:2000;365-372
52. Casolmo V., Spadero G., Patella V., Marone G. In vivo characterization of the anti-inflammatory effect of cyclosporine A on human basophils. J Immunol. 151:1993;5563-5573
53. Stellato C., de Paulis A., Ciccarelli A., Cirillo R., Patella A., Casolaro V., et al. Anti-inflmmatory effect of cyclosporin A on human skin mast cells. J Invest Dermatol. 98:1992;800-804
54. Lopez L.R., Davis K.C., Kohler P.F., et al. The hypocomplementeric urticarial-vasculitis syndrome: therapeutic response to hydroxychoroqine. J Allergy Clin Immunol. 73:1984;600-603
55. Versten J., Volkerts E.R., Von Osterwijck A.W.A.A., Arab M., Bijtjes S.I.R., DeWeert M., et al. Acute and subchronic effects of levocetirizine and dephenhydromone on memory functioning, psychomotor performance, and mood. J Allergy Clin Immunol. 111:2003;623-627
56. Weiler J.M., Bloom J.R., Woodworth G.G., Grant A.R., Layton T.A., Brown T.L., et al. Effects of fexofenadine, dephenhydramine, and alcohol on driving performance. A randomized, placebo-controlled trial in the Iowa driving simulator. Ann Intern Med. 132:2000;354-363
57. Bender B.G., Berning S., Dudden R., Milgran H., Tran Z.V. Sedational performance impairment of dephenhydramine and second-generation antihistaminics: a meta-analysis. J Allergy Clin Immunol. 111:2003;770-776
58. Poon E., Greaves M.W., Kobza-Black A. The extent and nature of disability in different urticaria conditions. Br J Dermatol. 140:1999;667-671