메뉴 건너뛰기




Volumn 8, Issue MAY, 2017, Pages

Autism spectrum disorders and schizophrenia spectrum disorders: Excitation/inhibition imbalance and developmental trajectories

Author keywords

Autism spectrum disorders; Children and adolescents; Excitation inhibition imbalance; Psychosis; Schizophrenia spectrum disorders

Indexed keywords

4 AMINOBUTYRIC ACID; EPIDERMAL GROWTH FACTOR RECEPTOR 4; GLUTAMATE DECARBOXYLASE 67; GLUTAMIC ACID; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUREXIN; NEUREXIN 1 ALPHA; NEUROLIGIN; NEUROLIGIN 1; UNCLASSIFIED DRUG;

EID: 85029573269     PISSN: None     EISSN: 16640640     Source Type: Journal    
DOI: 10.3389/fpsyt.2017.00069     Document Type: Article
Times cited : (103)

References (60)
  • 1
    • 84940870758 scopus 로고    scopus 로고
    • Schizophrenia and autism-related disorders
    • Hommer RE, Swedo SE. Schizophrenia and autism-related disorders. Schizophr Bull (2015) 41(2):313-4. doi:10.1093/schbul/sbu188
    • (2015) Schizophr Bull , vol.41 , Issue.2 , pp. 313-314
    • Hommer, R.E.1    Swedo, S.E.2
  • 2
    • 0003472502 scopus 로고    scopus 로고
    • 5th ed. Washington, DC: American Psychiatric Association
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Washington, DC: American Psychiatric Association (2013).
    • (2013) Diagnostic and Statistical Manual of Mental Disorders
  • 3
    • 58249135361 scopus 로고    scopus 로고
    • Autism spectrum disorders and childhood-onset schizophrenia: clinical and biological contributions to a relation revisited
    • Rapoport J, Chavez A, Greenstein D, Addington A, Gogtay N. Autism spectrum disorders and childhood-onset schizophrenia: clinical and biological contributions to a relation revisited. J Am Acad Child Adolesc Psychiatry (2009) 48(1):10-8. doi:10.1097/CHI.0b013e31818b1c63
    • (2009) J Am Acad Child Adolesc Psychiatry , vol.48 , Issue.1 , pp. 10-18
    • Rapoport, J.1    Chavez, A.2    Greenstein, D.3    Addington, A.4    Gogtay, N.5
  • 4
    • 84883553086 scopus 로고    scopus 로고
    • Childhood onset schizophrenia and early onset schizophrenia spectrum disorders
    • Driver DI, Gogtay N, Rapoport J. Childhood onset schizophrenia and early onset schizophrenia spectrum disorders. Child Adolesc Psychiatr Clin N Am (2013) 22(4):539-55. doi:10.1016/j.chc.2013.04.001
    • (2013) Child Adolesc Psychiatr Clin N Am , vol.22 , Issue.4 , pp. 539-555
    • Driver, D.I.1    Gogtay, N.2    Rapoport, J.3
  • 5
    • 79952315874 scopus 로고    scopus 로고
    • Is schizophrenia on the autism spectrum?
    • King BH, Lord C. Is schizophrenia on the autism spectrum? Brain Res (2011) 1380:34-41. doi:10.1016/j.brainres.2010.11.031
    • (2011) Brain Res , vol.1380 , pp. 34-41
    • King, B.H.1    Lord, C.2
  • 6
    • 84883558332 scopus 로고    scopus 로고
    • 'Autism-plus' spectrum disorders: intersection with psychosis and the schizophrenia spectrum
    • Cochran DM, Dvir Y, Frazier JA. 'Autism-plus' spectrum disorders: intersection with psychosis and the schizophrenia spectrum. Child Adolesc Psychiatr Clin N Am (2013) 22(4):609-27. doi:10.1016/j.chc.2013.04.005
    • (2013) Child Adolesc Psychiatr Clin N Am , vol.22 , Issue.4 , pp. 609-627
    • Cochran, D.M.1    Dvir, Y.2    Frazier, J.A.3
  • 7
    • 57749183060 scopus 로고    scopus 로고
    • Social cognition in schizophrenia: a review of face processing
    • Marwick K, Hall J. Social cognition in schizophrenia: a review of face processing. Br Med Bull (2008) 88(1):3-58. doi:10.1093/bmb/ldn035
    • (2008) Br Med Bull , vol.88 , Issue.1 , pp. 3-58
    • Marwick, K.1    Hall, J.2
  • 8
    • 84966355882 scopus 로고    scopus 로고
    • Context effects on facial affect recognition in schizophrenia and autism: behavioral and eye-tracking evidence
    • Sasson NJ, Pinkham AE, Weittenhiller LP, Faso DJ, Simpson C. Context effects on facial affect recognition in schizophrenia and autism: behavioral and eye-tracking evidence. Schizophr Bull (2016) 42(3):675-8. doi:10.1093/schbul/sbv176.3
    • (2016) Schizophr Bull , vol.42 , Issue.3 , pp. 675-678
    • Sasson, N.J.1    Pinkham, A.E.2    Weittenhiller, L.P.3    Faso, D.J.4    Simpson, C.5
  • 9
    • 84875886243 scopus 로고    scopus 로고
    • Revisiting the relationship between autism and schizophrenia: toward an integrated neurobiology
    • de Lacy N, King BH. Revisiting the relationship between autism and schizophrenia: toward an integrated neurobiology. Annu Rev Clin Psychol (2013) 9:555-87. doi:10.1146/annurev-clinpsy-050212-185627
    • (2013) Annu Rev Clin Psychol , vol.9 , pp. 555-587
    • de Lacy, N.1    King, B.H.2
  • 11
    • 84908483881 scopus 로고    scopus 로고
    • Maternal immune activation and abnormal brain development across CNS disorders
    • Knuesel I, Chicha L, Britschgi M, Schobel SA, Bodmer M, Hellings JA, et al. Maternal immune activation and abnormal brain development across CNS disorders. Nat Rev Neurol (2014) 10(11):643-60. doi:10.1038/nrneurol. 2014.187
    • (2014) Nat Rev Neurol , vol.10 , Issue.11 , pp. 643-660
    • Knuesel, I.1    Chicha, L.2    Britschgi, M.3    Schobel, S.A.4    Bodmer, M.5    Hellings, J.A.6
  • 12
    • 84930196553 scopus 로고    scopus 로고
    • Common mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disorders
    • Gao R, Penzes P. Common mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disorders. Curr Mol Med (2015) 15(2):146-67. doi:10.2174/1566524015666150303003028
    • (2015) Curr Mol Med , vol.15 , Issue.2 , pp. 146-167
    • Gao, R.1    Penzes, P.2
  • 13
    • 84866778001 scopus 로고    scopus 로고
    • GABAergic circuit dysfunctions in neurodevelopmental disorders
    • Chattopadhyaya B, Cristo GD. GABAergic circuit dysfunctions in neurodevelopmental disorders. Front Psychiatry (2012) 3:51. doi:10.3389/fpsyt.2012.00051
    • (2012) Front Psychiatry , vol.3 , pp. 51
    • Chattopadhyaya, B.1    Cristo, G.D.2
  • 14
    • 84884288041 scopus 로고    scopus 로고
    • Dendritic spine pathology in schizophrenia
    • Glausier JR, Lewis DA. Dendritic spine pathology in schizophrenia. Neuroscience (2013) 251:90-107. doi:10.1016/j.neuroscience.2012.04.044
    • (2013) Neuroscience , vol.251 , pp. 90-107
    • Glausier, J.R.1    Lewis, D.A.2
  • 15
    • 72049108920 scopus 로고    scopus 로고
    • Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders
    • Hutsler JJ, Zhang C. Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders. Brain Res (2010) 1309:83-94. doi:10.1016/j.brainres.2009.09.120
    • (2010) Brain Res , vol.1309 , pp. 83-94
    • Hutsler, J.J.1    Zhang, C.2
  • 16
    • 84860358233 scopus 로고    scopus 로고
    • Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism
    • Silverman JL, Smith DG, Rizzo SJ, Karras MN, Turner SM, Tolu SS, et al. Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism. Sci Transl Med (2012) 4(131):131-51. doi:10.1126/scitranslmed.3003501
    • (2012) Sci Transl Med , vol.4 , Issue.131 , pp. 131-151
    • Silverman, J.L.1    Smith, D.G.2    Rizzo, S.J.3    Karras, M.N.4    Turner, S.M.5    Tolu, S.S.6
  • 17
    • 84937164423 scopus 로고    scopus 로고
    • GABAB receptor agonist r-baclofen reverses social deficits and reduces repetitive behavior in two mouse models of autism
    • Silverman JL, Pride MC, Hayes JE, Puhger KR, Butler-Struben HM, Baker S, et al. GABAB receptor agonist r-baclofen reverses social deficits and reduces repetitive behavior in two mouse models of autism. Neuropsychopharmacology (2015) 40(9):2228-39. doi:10.1038/npp.2015.66
    • (2015) Neuropsychopharmacology , vol.40 , Issue.9 , pp. 2228-2239
    • Silverman, J.L.1    Pride, M.C.2    Hayes, J.E.3    Puhger, K.R.4    Butler-Struben, H.M.5    Baker, S.6
  • 18
    • 84869213888 scopus 로고    scopus 로고
    • Synapse dysfunction in autism: a molecular medicine approach to drug discovery in neurodevelopmental disorders
    • Spooren W, Lindemann L, Ghosh A, Santarelli L. Synapse dysfunction in autism: a molecular medicine approach to drug discovery in neurodevelopmental disorders. Trends Pharmacol Sci (2012) 33(12):669-84. doi:10.1016/j. tips.2012.09.004
    • (2012) Trends Pharmacol Sci , vol.33 , Issue.12 , pp. 669-684
    • Spooren, W.1    Lindemann, L.2    Ghosh, A.3    Santarelli, L.4
  • 19
    • 84856110031 scopus 로고    scopus 로고
    • The role of neurexins in schizophrenia and autistic spectrum disorder
    • Reichelt AC, Rodgers RJ, Clapcote SJ. The role of neurexins in schizophrenia and autistic spectrum disorder. Neuropharmacology (2012) 62(3):1519-26. doi:10.1016/j.neuropharm.2011.01.024
    • (2012) Neuropharmacology , vol.62 , Issue.3 , pp. 1519-1526
    • Reichelt, A.C.1    Rodgers, R.J.2    Clapcote, S.J.3
  • 20
    • 84879522237 scopus 로고    scopus 로고
    • Altered social behaviours in neurexin 1alpha knockout mice resemble core symptoms in neurodevelopmental disorders
    • Grayton HM, Missler M, Collier DA, Fernandes C. Altered social behaviours in neurexin 1alpha knockout mice resemble core symptoms in neurodevelopmental disorders. PLoS One (2013) 8:e67114. doi:10.1371/journal. pone.0067114
    • (2013) PLoS One , vol.8
    • Grayton, H.M.1    Missler, M.2    Collier, D.A.3    Fernandes, C.4
  • 21
    • 84876738375 scopus 로고    scopus 로고
    • Targeting glia cells: novel perspectives for the treatment of neuropsychiatric diseases
    • Di Benedetto B, Rupprecht R. Targeting glia cells: novel perspectives for the treatment of neuropsychiatric diseases. Curr Neuropharmacol (2013) 11:171-85. doi:10.2174/1570159X11311020004
    • (2013) Curr Neuropharmacol , vol.11 , pp. 171-185
    • Di Benedetto, B.1    Rupprecht, R.2
  • 22
    • 84957606739 scopus 로고    scopus 로고
    • Targeting glia with N-acetylcysteine modulates brain glutamate and behaviors relevant to neurodevelopmental disorders in C57BL/6J mice
    • Durieux AMS, Fernandes C, Murphy D, Labouesse MA, Giovanoli S, Meyer U, et al. Targeting glia with N-acetylcysteine modulates brain glutamate and behaviors relevant to neurodevelopmental disorders in C57BL/6J mice. Front Behav Neurosci (2015) 9:343. doi:10.3389/fnbeh.2015.00343
    • (2015) Front Behav Neurosci , vol.9 , pp. 343
    • Durieux, A.M.S.1    Fernandes, C.2    Murphy, D.3    Labouesse, M.A.4    Giovanoli, S.5    Meyer, U.6
  • 23
    • 58549113548 scopus 로고    scopus 로고
    • GABA(A) receptor downregulation in brains of subjects with autism
    • Fatemi SH, Reutiman TJ, Folsom TD, Thuras PD. GABA(A) receptor downregulation in brains of subjects with autism. J Autism Dev Disord (2009) 39(2):223-30. doi:10.1007/s10803-008-0646-7
    • (2009) J Autism Dev Disord , vol.39 , Issue.2 , pp. 223-230
    • Fatemi, S.H.1    Reutiman, T.J.2    Folsom, T.D.3    Thuras, P.D.4
  • 24
    • 84920666512 scopus 로고    scopus 로고
    • Glial cells as key players in schizophrenia pathology: recent insights and concepts of therapy
    • Bernstein HG, Steiner J, Guest PC, Dobrowolny H, Bogerts B. Glial cells as key players in schizophrenia pathology: recent insights and concepts of therapy. Schizophr Res (2015) 161(1):4-18. doi:10.1016/j.schres.2014.03.035
    • (2015) Schizophr Res , vol.161 , Issue.1 , pp. 4-18
    • Bernstein, H.G.1    Steiner, J.2    Guest, P.C.3    Dobrowolny, H.4    Bogerts, B.5
  • 25
    • 84857190395 scopus 로고    scopus 로고
    • The role of immune dysfunction in the pathophysiology of autism
    • Onore C, Careaga M, Ashwood P. The role of immune dysfunction in the pathophysiology of autism. Brain Behav Immun (2012) 26(3):383-92. doi:10.1016/j.bbi.2011.08.007
    • (2012) Brain Behav Immun , vol.26 , Issue.3 , pp. 383-392
    • Onore, C.1    Careaga, M.2    Ashwood, P.3
  • 26
    • 84945232126 scopus 로고    scopus 로고
    • Excitatory/inhibitory imbalance in autism spectrum disorders: implications for interventions and therapeutics
    • Uzunova G, Pallanti S, Hollander E. Excitatory/inhibitory imbalance in autism spectrum disorders: implications for interventions and therapeutics. World J Biol Psychiatry (2016) 17(3):174-86. doi:10.3109/15622975.2015.10 85597
    • (2016) World J Biol Psychiatry , vol.17 , Issue.3 , pp. 174-186
    • Uzunova, G.1    Pallanti, S.2    Hollander, E.3
  • 27
    • 84959236937 scopus 로고    scopus 로고
    • Review: cortical construction in autism spectrum disorder: columns, connectivity and the subplate
    • Hutsler JJ, Casanova M. Review: cortical construction in autism spectrum disorder: columns, connectivity and the subplate. Neuropathol Appl Neurobiol (2016) 42(2):115-34. doi:10.1111/nan.12227
    • (2016) Neuropathol Appl Neurobiol , vol.42 , Issue.2 , pp. 115-134
    • Hutsler, J.J.1    Casanova, M.2
  • 28
    • 84903512633 scopus 로고    scopus 로고
    • Prefrontal cortical minicolumn: from executive control to disrupted cognitive processing
    • Opris I, Casanova MF. Prefrontal cortical minicolumn: from executive control to disrupted cognitive processing. Brain (2014) 137(7):1863-75. doi:10.1093/brain/awt359
    • (2014) Brain , vol.137 , Issue.7 , pp. 1863-1875
    • Opris, I.1    Casanova, M.F.2
  • 29
    • 79960627779 scopus 로고    scopus 로고
    • An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus
    • Etherton MR, Tabuchi K, Harma SM, Ko J, Sudhof TC. An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus. EMBO J (2011) 30(14):2908-19. doi:10.1038/emboj.2011.182
    • (2011) EMBO J , vol.30 , Issue.14 , pp. 2908-2919
    • Etherton, M.R.1    Tabuchi, K.2    Harma, S.M.3    Ko, J.4    Sudhof, T.C.5
  • 30
    • 69749113369 scopus 로고    scopus 로고
    • A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export
    • Zhang C, Milunsky JM, Newton S, Ko J, Zhao G, Maher TA, et al. A neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum export. J Neurosci (2009) 29(35):10843-54. doi:10.1523/JNEUROSCI.1248-09.2009
    • (2009) J Neurosci , vol.29 , Issue.35 , pp. 10843-10854
    • Zhang, C.1    Milunsky, J.M.2    Newton, S.3    Ko, J.4    Zhao, G.5    Maher, T.A.6
  • 31
    • 80054860297 scopus 로고    scopus 로고
    • Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia
    • Gauthier J, Siddiqui TJ, Huashan P, Yokomaku D, Hamdan FF, Champagne N, et al. Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia. Hum Genet (2011) 130(4):563-73. doi:10.1007/s00439-011-0975-z
    • (2011) Hum Genet , vol.130 , Issue.4 , pp. 563-573
    • Gauthier, J.1    Siddiqui, T.J.2    Huashan, P.3    Yokomaku, D.4    Hamdan, F.F.5    Champagne, N.6
  • 32
    • 84960111021 scopus 로고    scopus 로고
    • Phelan-McDermid syndrome: a review of the literature and practice parameters for medical assessment and monitoring
    • Kolevzon A, Angarita B, Bush L, Wang AT, Frank Y, Yang A, et al. Phelan-McDermid syndrome: a review of the literature and practice parameters for medical assessment and monitoring. J Neurodev Disord (2014) 6:39. doi:10.1186/1866-1955-6-39
    • (2014) J Neurodev Disord , vol.6 , pp. 39
    • Kolevzon, A.1    Angarita, B.2    Bush, L.3    Wang, A.T.4    Frank, Y.5    Yang, A.6
  • 33
    • 84907572367 scopus 로고    scopus 로고
    • Meta-analysis of SHANK mutations in autism spectrum disorders: a gradient of severity in cognitive impairments
    • Leblond CS, Nava C, Polge A, Jauthier G, Huguet G, Lumbroso S, et al. Meta-analysis of SHANK mutations in autism spectrum disorders: a gradient of severity in cognitive impairments. PLoS Genet (2014) 10(9):e1004580. doi:10.1371/journal.pgen.1004580
    • (2014) PLoS Genet , vol.10 , Issue.9
    • Leblond, C.S.1    Nava, C.2    Polge, A.3    Jauthier, G.4    Huguet, G.5    Lumbroso, S.6
  • 34
    • 84959539365 scopus 로고    scopus 로고
    • Reduced GABAergic action in the autistic brain
    • Robertson CE, Ratai EM, Kanwisher N. Reduced GABAergic action in the autistic brain. Curr Biol (2016) 26(1):80-5. doi:10.1016/j.cub.2015.11.019
    • (2016) Curr Biol , vol.26 , Issue.1 , pp. 80-85
    • Robertson, C.E.1    Ratai, E.M.2    Kanwisher, N.3
  • 35
    • 77955170379 scopus 로고    scopus 로고
    • Decreased GABA(B) receptors in the cingulate cortex and fusiform gyrus in autism
    • Oblak AL, Gibbs TT, Blatt GJ. Decreased GABA(B) receptors in the cingulate cortex and fusiform gyrus in autism. J Neurochem (2010) 114(5):1414-23. doi:10.1111/j.1471-4159.2010.06858.x
    • (2010) J Neurochem , vol.114 , Issue.5 , pp. 1414-1423
    • Oblak, A.L.1    Gibbs, T.T.2    Blatt, G.J.3
  • 36
    • 84937212591 scopus 로고    scopus 로고
    • FOXG1-dependent dysregulation of GABA/glutamate neuron differentiation in autism spectrum disorders
    • Mariani J, Coppola G, Zhang P, Abyzov A, Provini L, Tomasini L, et al. FOXG1-dependent dysregulation of GABA/glutamate neuron differentiation in autism spectrum disorders. Cell (2015) 16(162):375-90. doi:10.1016/j. cell.2015.06.034 37. Lewis DA. The chandelier neuron in schizophrenia. Dev Neurobiol (2011) 1(71):118-27. doi:10.1002/dneu.20825
    • (2015) Cell , vol.16 , Issue.162 , pp. 375-390
    • Mariani, J.1    Coppola, G.2    Zhang, P.3    Abyzov, A.4    Provini, L.5    Tomasini, L.6
  • 37
    • 78650060737 scopus 로고    scopus 로고
    • The chandelier neuron in schizophrenia
    • Lewis DA. The chandelier neuron in schizophrenia. Dev Neurobiol (2011) 1(71):118-27. doi:10.1002/dneu.20825
    • (2011) Dev Neurobiol , vol.1 , Issue.71 , pp. 118-127
    • Lewis, D.A.1
  • 38
    • 54149109208 scopus 로고    scopus 로고
    • GABA neurons and the mechanisms of network oscillations: implications for understanding cortical dysfunction in schizophrenia
    • Gonzalez-Burgos G, Lewis DA. GABA neurons and the mechanisms of network oscillations: implications for understanding cortical dysfunction in schizophrenia. Schizophr Bull (2008) 34(5):944-61. doi:10.1093/schbul/sbn070
    • (2008) Schizophr Bull , vol.34 , Issue.5 , pp. 944-961
    • Gonzalez-Burgos, G.1    Lewis, D.A.2
  • 39
    • 84878254691 scopus 로고    scopus 로고
    • NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
    • Paoletti R, Bellone C, Zhou Q. NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease. Nat Rev Neurosci (2013) 14(6):383-400. doi:10.1038/nrn3504
    • (2013) Nat Rev Neurosci , vol.14 , Issue.6 , pp. 383-400
    • Paoletti, R.1    Bellone, C.2    Zhou, Q.3
  • 40
    • 67749088757 scopus 로고    scopus 로고
    • Altered excitatory-inhibitory balance in the NMDA-hypofunction model of schizophrenia
    • Kehrer C, Maziashvili N, Dugladze T, Gloveli T. Altered excitatory-inhibitory balance in the NMDA-hypofunction model of schizophrenia. Front Mol Neurosci (2008) 8(1):6. doi:10.3389/neuro.02.006.2008
    • (2008) Front Mol Neurosci , vol.8 , Issue.1 , pp. 6
    • Kehrer, C.1    Maziashvili, N.2    Dugladze, T.3    Gloveli, T.4
  • 41
    • 84959573573 scopus 로고    scopus 로고
    • The NMDA receptor and schizophrenia: from pathophysiology to treatment
    • Balu DT. The NMDA receptor and schizophrenia: from pathophysiology to treatment. Adv Pharmacol (2016) 76:351-82. doi:10.1016/bs.apha.2016.01.006
    • (2016) Adv Pharmacol , vol.76 , pp. 351-382
    • Balu, D.T.1
  • 42
  • 43
    • 84875952213 scopus 로고    scopus 로고
    • NMDA hypofunction as a convergence point for progression and symptoms of schizophrenia
    • Snyder MA, Gao WJ. NMDA hypofunction as a convergence point for progression and symptoms of schizophrenia. Front Cell Neurosci (2013) 27(7):31. doi:10.3389/fncel.2013.00031
    • (2013) Front Cell Neurosci , vol.27 , Issue.7 , pp. 31
    • Snyder, M.A.1    Gao, W.J.2
  • 44
    • 79959262465 scopus 로고    scopus 로고
    • Transcriptomic analysis of autistic brain reveals convergent molecular pathology
    • Voineagau I, Wang X, Johnston P, Tian Y, Horvath S, Mill J, et al. Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature (2011) 474(7351):380-4. doi:10.1038/nature10110
    • (2011) Nature , vol.474 , Issue.7351 , pp. 380-384
    • Voineagau, I.1    Wang, X.2    Johnston, P.3    Tian, Y.4    Horvath, S.5    Mill, J.6
  • 45
    • 81555218550 scopus 로고    scopus 로고
    • Rare mutations in N-methyl-d-aspartate glutamate receptors in autism spectrum disorders and schizophrenia
    • Tarabeux J, Kebir O, Gauthier J, Hamdan FF, Xiong L, Piton A, et al. Rare mutations in N-methyl-d-aspartate glutamate receptors in autism spectrum disorders and schizophrenia. Transl Psychiatry (2011) 15(1):e55. doi:10.1038/tp.2011.52
    • (2011) Transl Psychiatry , vol.15 , Issue.1
    • Tarabeux, J.1    Kebir, O.2    Gauthier, J.3    Hamdan, F.F.4    Xiong, L.5    Piton, A.6
  • 46
    • 77956652609 scopus 로고    scopus 로고
    • Neuregulin 1-erbB4 pathway in schizophrenia: from genes to an interactome
    • Banerjee A, Macdonald ML, Borgmann-Winter KE, Hahn CG. Neuregulin 1-erbB4 pathway in schizophrenia: from genes to an interactome. Brain Res Bull (2010) 83(3-4):132-9. doi:10.1016/j.brainresbull.2010.04.011
    • (2010) Brain Res Bull , vol.83 , Issue.3-4 , pp. 132-139
    • Banerjee, A.1    Macdonald, M.L.2    Borgmann-Winter, K.E.3    Hahn, C.G.4
  • 47
    • 84954052750 scopus 로고    scopus 로고
    • ErbB4 in laminated brain structures: a neurodevelopmental approach to schizophrenia
    • Perez-Garcia CG. ErbB4 in laminated brain structures: a neurodevelopmental approach to schizophrenia. Front Cell Neurosci (2015) 18(9):472. doi:10.3389/fncel.2015.00472
    • (2015) Front Cell Neurosci , vol.18 , Issue.9 , pp. 472
    • Perez-Garcia, C.G.1
  • 48
    • 33846873634 scopus 로고    scopus 로고
    • Role of DISC1 in neural development and schizophrenia
    • Mackie S, Millar JK, Porteous DJ. Role of DISC1 in neural development and schizophrenia. Curr Opin Neurobiol (2007) 17(1):95-102. doi:10.1016/j. conb.2007.01.007
    • (2007) Curr Opin Neurobiol , vol.17 , Issue.1 , pp. 95-102
    • Mackie, S.1    Millar, J.K.2    Porteous, D.J.3
  • 49
    • 84856118476 scopus 로고    scopus 로고
    • DISC1-binding proteins in neural development, signalling and schizophrenia
    • Bradshaw NJ, DJ Porteous DJ. DISC1-binding proteins in neural development, signalling and schizophrenia. Neuropharmacology (2012) 62(3):1230-41. doi:10.1016/j.neuropharm.2010.12.027
    • (2012) Neuropharmacology , vol.62 , Issue.3 , pp. 1230-1241
    • Bradshaw, N.J.1    D.J Porteous, D.J.2
  • 50
    • 85008347714 scopus 로고    scopus 로고
    • Are hallucinations due to an imbalance between excitatory and inhibitory influences on the brain?
    • Jardri R, Hugdahl K, Hughes M, Brunelin J, Waters F, Alderson-Day B, et al. Are hallucinations due to an imbalance between excitatory and inhibitory influences on the brain? Schizophr Bull (2016) 42(5):1124-34. doi:10.1093/schbul/sbw075
    • (2016) Schizophr Bull , vol.42 , Issue.5 , pp. 1124-1134
    • Jardri, R.1    Hugdahl, K.2    Hughes, M.3    Brunelin, J.4    Waters, F.5    Alderson-Day, B.6
  • 51
    • 84901937317 scopus 로고    scopus 로고
    • Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome
    • Schneider M, Debbane M, Bassett AS, Chow EW, Fung WL, van den Bree M, et al. Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome. Am J Psychiatry (2014) 171(6):627-39. doi:10.1176/appi.ajp.2013.13070864
    • (2014) Am J Psychiatry , vol.171 , Issue.6 , pp. 627-639
    • Schneider, M.1    Debbane, M.2    Bassett, A.S.3    Chow, E.W.4    Fung, W.L.5    van den Bree, M.6
  • 52
    • 84953839767 scopus 로고    scopus 로고
    • Mice with Shank3 mutations associated with ASD and schizophrenia display both shared and distinct defects
    • Zhou Y, Kaiser T, Monteiro P, Zhang X, Van der Goes MS, Wang D, et al. Mice with Shank3 mutations associated with ASD and schizophrenia display both shared and distinct defects. Neuron (2016) 89(1):147-62. doi:10.1016/j. neuron.2015.11.023
    • (2016) Neuron , vol.89 , Issue.1 , pp. 147-162
    • Zhou, Y.1    Kaiser, T.2    Monteiro, P.3    Zhang, X.4    Van der Goes, M.S.5    Wang, D.6
  • 53
    • 84974687454 scopus 로고    scopus 로고
    • mTOR, a potential target to treat autism spectrum disorder
    • Sato A. mTOR, a potential target to treat autism spectrum disorder. CNS Neurol Disord Drug Targets (2016) 15(5):533-43. doi:10.2174/18715273156 66160413120638
    • (2016) CNS Neurol Disord Drug Targets , vol.15 , Issue.5 , pp. 533-543
    • Sato, A.1
  • 54
    • 84875921248 scopus 로고    scopus 로고
    • Reversing autism by targeting downstream mTOR signaling
    • Wang H, Doering LC. Reversing autism by targeting downstream mTOR signaling. Front Cell Neurosci (2013) 7:28. doi:10.3389/fncel.2013.00028
    • (2013) Front Cell Neurosci , vol.7 , pp. 28
    • Wang, H.1    Doering, L.C.2
  • 55
    • 84898949603 scopus 로고    scopus 로고
    • Is the mTOR-signalling cascade disrupted in schizophrenia? J Neurochem (2014) 129(3):377-87
    • Gururajan A, van den Buuse M. Is the mTOR-signalling cascade disrupted in schizophrenia? J Neurochem (2014) 129(3):377-87. doi:10.1111/jnc.12622
    • doi:10.1111/jnc.12622
    • Gururajan, A.1    van den Buuse, M.2
  • 56
    • 84864965624 scopus 로고    scopus 로고
    • Multiple roles for mammalian target of rapamycin signaling in both glutamatergic and GABAergic synaptic transmission
    • Weston MC, Chen H, Swann JW. Multiple roles for mammalian target of rapamycin signaling in both glutamatergic and GABAergic synaptic transmission. J Neurosci (2012) 32(33):11441-52. doi:10.1523/JNEUROSCI.1283-12.2012
    • (2012) J Neurosci , vol.32 , Issue.33 , pp. 11441-11452
    • Weston, M.C.1    Chen, H.2    Swann, J.W.3
  • 57
    • 65349191920 scopus 로고    scopus 로고
    • The neurodevelopmental hypothesis of schizophrenia, revisited
    • Fatemi SH, Folsom TD. The neurodevelopmental hypothesis of schizophrenia, revisited. Schizophr Bull (2009) 35(3):528-48. doi:10.1093/schbul/sbn187
    • (2009) Schizophr Bull , vol.35 , Issue.3 , pp. 528-548
    • Fatemi, S.H.1    Folsom, T.D.2
  • 58
    • 84886826594 scopus 로고    scopus 로고
    • mTOR complexes in neurodevelopmental and neuropsychiatric disorders
    • Costa-Mattioli M, Monteggia LM. mTOR complexes in neurodevelopmental and neuropsychiatric disorders. Nat Neurosci (2013) 16(11):1537-43. doi:10.1038/nn.3546
    • (2013) Nat Neurosci , vol.16 , Issue.11 , pp. 1537-1543
    • Costa-Mattioli, M.1    Monteggia, L.M.2
  • 59
    • 84959484235 scopus 로고    scopus 로고
    • The National Institute of Mental Health research domain criteria and clinical research in child and adolescent psychiatry
    • Garvey M, Avenevoli S, Anderson K. The National Institute of Mental Health research domain criteria and clinical research in child and adolescent psychiatry. J Am Acad Child Adolesc Psychiatry (2016) 55(2):93-8. doi:10.1016/j. jaac.2015.11.002
    • (2016) J Am Acad Child Adolesc Psychiatry , vol.55 , Issue.2 , pp. 93-98
    • Garvey, M.1    Avenevoli, S.2    Anderson, K.3
  • 60
    • 84893511145 scopus 로고    scopus 로고
    • The RDoC framework: facilitating transition from ICD/DSM to dimensional approaches that integrate neuroscience and psychopathology
    • Cuthbert BN. The RDoC framework: facilitating transition from ICD/DSM to dimensional approaches that integrate neuroscience and psychopathology. World Psychiatry (2014) 13(1):28-35. doi:10.1002/wps.20087
    • (2014) World Psychiatry , vol.13 , Issue.1 , pp. 28-35
    • Cuthbert, B.N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.