Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

Neuron

Volumn 89, Issue 1, 2016, Pages 147-162

  Zhou, Yang ^a,f   Kaiser, Tobias ^a   Monteiro, Patrícia ^a,d,e   Zhang, Xiangyu ^a   Van der Goes, Marie S ^a   Wang, Dongqing ^a   Barak, Boaz ^a   Zeng, Menglong ^a,g   Li, Chenchen ^a,d   Lu, Congyi ^a,d   Wells, Michael ^a,h   Amaya, Aldo ^d   Nguyen, Shannon ^d   Lewis, Michael ^d   Sanjana, Neville ^a,d   Zhou, Yongdi ^f   Zhang, Mingjie ^g   Zhang, Feng ^a,b,c,d   Fu, Zhanyan ^a,d   Feng, Guoping ^a,b,d  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c Massachusetts Institute of Technology Cambridge   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e UNIVERSITY OF COIMBRA   (Portugal)

^f B326 Science Building   (China)

^g HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^h DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; MESSENGER RNA; PROTEIN SHANK1; PROTEIN SHANK2; PROTEIN SHANK3; UNCLASSIFIED DRUG; NERVE PROTEIN; SHANK1 PROTEIN, MOUSE; SHANK2 PROTEIN, MOUSE; SHANK3 PROTEIN, MOUSE;

AGE; ALLELE; ALTERNATIVE RNA SPLICING; AMINO TERMINAL SEQUENCE; ARTICLE; AUTISM; BEHAVIOR; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE MUTATION; GENETIC ASSOCIATION; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN CELL; MALE; MOLECULAR BIOLOGY; MOUSE; MUTATIONAL ANALYSIS; NEUROTRANSMISSION; NONHUMAN; ONSET AGE; PATHOGENESIS; PHENOTYPE; POSTSYNAPTIC DENSITY; PREFRONTAL CORTEX; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RNA STABILITY; SCHIZOPHRENIA; SHANK1 GENE; SHANK2 GENE; SHANK3 GENE; SOCIAL DOMINANCE; SOCIAL INTERACTION; SPECIES DIFFERENTIATION; SPINE DENSITY; STOP CODON; SYMPTOMATOLOGY; SYNAPSE; UPREGULATION; AGING; ANIMAL; ANIMAL BEHAVIOR; DISEASE MODEL; GENETICS; HIPPOCAMPUS; METABOLISM; MUTATION; NERVE CELL; PATHOPHYSIOLOGY; SOCIAL BEHAVIOR; SYNAPTIC TRANSMISSION; TRANSGENIC MOUSE;

AGING; ANIMALS; AUTISM SPECTRUM DISORDER; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; MICE, TRANSGENIC; MUTATION; NERVE TISSUE PROTEINS; NEURONS; SCHIZOPHRENIA; SOCIAL BEHAVIOR; SYNAPTIC TRANSMISSION;

EID: 84953839767     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2015.11.023     Document Type: Article

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