메뉴 건너뛰기




Volumn 8, Issue , 2017, Pages 508-519

Erratum: LRRK2 Antisense Oligonucleotides Ameliorate α-Synuclein Inclusion Formation in a Parkinson's Disease Mouse Model (Molecular Therapy - Nucleic Acids (2017) 8 (508–519), (S2162253117302287), (10.1016/j.omtn.2017.08.002));LRRK2 Antisense Oligonucleotides Ameliorate α-Synuclein Inclusion Formation in a Parkinson's Disease Mouse Model

Author keywords

antisense oligonucleotides; LRRK2; Parkinson's disease; preformed fibrils; synuclein

Indexed keywords

ALPHA SYNUCLEIN; ANTISENSE OLIGONUCLEOTIDE; LEUCINE RICH REPEAT KINASE 2; TYROSINE 3 MONOOXYGENASE;

EID: 85029310621     PISSN: None     EISSN: 21622531     Source Type: Journal    
DOI: 10.1016/j.omtn.2021.05.013     Document Type: Erratum
Times cited : (158)

References (55)
  • 1
    • 0031910093 scopus 로고    scopus 로고
    • Aggregation of neurofilament and alpha-synuclein proteins in Lewy bodies: implications for the pathogenesis of Parkinson disease and Lewy body dementia
    • Trojanowski, J.Q., Lee, V.M., Aggregation of neurofilament and alpha-synuclein proteins in Lewy bodies: implications for the pathogenesis of Parkinson disease and Lewy body dementia. Arch. Neurol. 55 (1998), 151–152.
    • (1998) Arch. Neurol. , vol.55 , pp. 151-152
    • Trojanowski, J.Q.1    Lee, V.M.2
  • 5
    • 84863237380 scopus 로고    scopus 로고
    • α-synuclein, LRRK2 and their interplay in Parkinson's disease
    • Liu, G., Aliaga, L., Cai, H., α-synuclein, LRRK2 and their interplay in Parkinson's disease. Future Neurol. 7 (2012), 145–153.
    • (2012) Future Neurol. , vol.7 , pp. 145-153
    • Liu, G.1    Aliaga, L.2    Cai, H.3
  • 8
    • 84981164616 scopus 로고    scopus 로고
    • Identification of bona-fide LRRK2 kinase substrates
    • West, A.B., Cookson, M.R., Identification of bona-fide LRRK2 kinase substrates. Mov. Disord. 31 (2016), 1140–1141.
    • (2016) Mov. Disord. , vol.31 , pp. 1140-1141
    • West, A.B.1    Cookson, M.R.2
  • 13
    • 85176842928 scopus 로고    scopus 로고
    • Single and Multiple Dose Study of BIIB067 in Adults with Amyotrophic Lateral Sclerosis (ALS).
    • Single and Multiple Dose Study of BIIB067 in Adults with Amyotrophic Lateral Sclerosis (ALS). https://ClinicalTrials.gov/show/NCT02623699.
  • 14
    • 85176856760 scopus 로고    scopus 로고
    • Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS-HTTRx in Patients with Early Manifest Huntington's Disease.
    • Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS-HTTRx in Patients with Early Manifest Huntington's Disease. https://ClinicalTrials.gov/show/NCT02519036.
  • 15
    • 85176830552 scopus 로고    scopus 로고
    • An Open-Label Safety, Tolerability, and Dose-Range Finding Study of Nusinersen (ISIS 396443) in Participants with Spinal Muscular Atrophy (SMA) (SMNRx).
    • An Open-Label Safety, Tolerability, and Dose-Range Finding Study of Nusinersen (ISIS 396443) in Participants with Spinal Muscular Atrophy (SMA) (SMNRx). https://ClinicalTrials.gov/show/NCT01494701.
  • 16
    • 85176843716 scopus 로고    scopus 로고
    • An Open-Label Safety, Tolerability and Dose-Range Finding Study of Multiple Doses of Nusinersen (ISIS 396443) in Participants with Spinal Muscular Atrophy.
    • An Open-Label Safety, Tolerability and Dose-Range Finding Study of Multiple Doses of Nusinersen (ISIS 396443) in Participants with Spinal Muscular Atrophy. https://ClinicalTrials.gov/show/NCT01703988.
  • 17
    • 85176829807 scopus 로고    scopus 로고
    • An Open-Label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants with Spinal Muscular Atrophy Who Previously Participated in ISIS 396443-CS1 (NCT01494701).
    • An Open-Label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants with Spinal Muscular Atrophy Who Previously Participated in ISIS 396443-CS1 (NCT01494701). https://ClinicalTrials.gov/show/NCT01780246.
  • 18
    • 85176840618 scopus 로고    scopus 로고
    • An Open-Label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants with Spinal Muscular Atrophy (SMA) Who Previously Participated in ISIS 396443-CS2 (NCT01703988) or ISIS 396443-CS10 (NCT01780246).
    • An Open-Label Safety and Tolerability Study of Nusinersen (ISIS 396443) in Participants with Spinal Muscular Atrophy (SMA) Who Previously Participated in ISIS 396443-CS2 (NCT01703988) or ISIS 396443-CS10 (NCT01780246). https://ClinicalTrials.gov/show/NCT02052791.
  • 19
    • 85176851858 scopus 로고    scopus 로고
    • A Study to Assess the Efficacy, Safety and Pharmacokinetics of Nusinersen (ISIS 396443) in Infants with Spinal Muscular Atrophy (SMA).
    • A Study to Assess the Efficacy, Safety and Pharmacokinetics of Nusinersen (ISIS 396443) in Infants with Spinal Muscular Atrophy (SMA). https://ClinicalTrials.gov/show/NCT01839656.
  • 20
    • 85176863892 scopus 로고    scopus 로고
    • A Study for Participants with Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies (SHINE).
    • A Study for Participants with Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies (SHINE). https://ClinicalTrials.gov/show/NCT02594124.
  • 21
    • 85176866334 scopus 로고    scopus 로고
    • A Study to Assess the Safety and Tolerability of Nusinersen (ISIS 396443) in Participants with Spinal Muscular Atrophy (SMA) (EMBRACE).
    • A Study to Assess the Safety and Tolerability of Nusinersen (ISIS 396443) in Participants with Spinal Muscular Atrophy (SMA) (EMBRACE). https://ClinicalTrials.gov/show/NCT02462759.
  • 22
    • 85176863726 scopus 로고    scopus 로고
    • A Study of Multiple Doses of Nusinersen (ISIS 396443) Delivered to Infants with Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy (NUTURE).
    • A Study of Multiple Doses of Nusinersen (ISIS 396443) Delivered to Infants with Genetically Diagnosed and Presymptomatic Spinal Muscular Atrophy (NUTURE). https://ClinicalTrials.gov/show/NCT02386553.
  • 23
    • 85176822077 scopus 로고    scopus 로고
    • for Nusinersen in Participants with Infantile-Onset (Consistent with Type 1) Spinal Muscular Atrophy (SMA).
    • Expanded Access Program (EAP) for Nusinersen in Participants with Infantile-Onset (Consistent with Type 1) Spinal Muscular Atrophy (SMA). https://ClinicalTrials.gov/show/NCT02865109.
  • 24
    • 85176862925 scopus 로고    scopus 로고
    • A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Participants with Later-Onset Spinal Muscular Atrophy (SMA) (CHERISH).
    • A Study to Assess the Efficacy and Safety of Nusinersen (ISIS 396443) in Participants with Later-Onset Spinal Muscular Atrophy (SMA) (CHERISH). https://ClinicalTrials.gov/show/NCT02292537.
  • 25
    • 61349102407 scopus 로고    scopus 로고
    • Ribonuclease H: the enzymes in eukaryotes
    • Cerritelli, S.M., Crouch, R.J., Ribonuclease H: the enzymes in eukaryotes. FEBS J. 276 (2009), 1494–1505.
    • (2009) FEBS J. , vol.276 , pp. 1494-1505
    • Cerritelli, S.M.1    Crouch, R.J.2
  • 27
    • 84890319075 scopus 로고    scopus 로고
    • Characterization of target mRNA reduction through in situ RNA hybridization in multiple organ systems following systemic antisense treatment in animals
    • Hung, G., Xiao, X., Peralta, R., Bhattacharjee, G., Murray, S., Norris, D., Guo, S., Monia, B.P., Characterization of target mRNA reduction through in situ RNA hybridization in multiple organ systems following systemic antisense treatment in animals. Nucleic Acid Ther. 23 (2013), 369–378.
    • (2013) Nucleic Acid Ther. , vol.23 , pp. 369-378
    • Hung, G.1    Xiao, X.2    Peralta, R.3    Bhattacharjee, G.4    Murray, S.5    Norris, D.6    Guo, S.7    Monia, B.P.8
  • 29
    • 84903546492 scopus 로고    scopus 로고
    • Pharmacology of a central nervous system delivered 2′-O-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates
    • Rigo, F., Chun, S.J., Norris, D.A., Hung, G., Lee, S., Matson, J., Fey, R.A., Gaus, H., Hua, Y., Grundy, J.S., et al. Pharmacology of a central nervous system delivered 2′-O-methoxyethyl-modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates. J. Pharmacol. Exp. Ther. 350 (2014), 46–55.
    • (2014) J. Pharmacol. Exp. Ther. , vol.350 , pp. 46-55
    • Rigo, F.1    Chun, S.J.2    Norris, D.A.3    Hung, G.4    Lee, S.5    Matson, J.6    Fey, R.A.7    Gaus, H.8    Hua, Y.9    Grundy, J.S.10
  • 31
    • 84903441419 scopus 로고    scopus 로고
    • A-synuclein immunotherapy blocks uptake and templated propagation of misfolded α-synuclein and neurodegeneration
    • Tran, H.T., Chung, C.H., Iba, M., Zhang, B., Trojanowski, J.Q., Luk, K.C., Lee, V.M., A-synuclein immunotherapy blocks uptake and templated propagation of misfolded α-synuclein and neurodegeneration. Cell Rep. 7 (2014), 2054–2065.
    • (2014) Cell Rep. , vol.7 , pp. 2054-2065
    • Tran, H.T.1    Chung, C.H.2    Iba, M.3    Zhang, B.4    Trojanowski, J.Q.5    Luk, K.C.6    Lee, V.M.7
  • 36
    • 84869109864 scopus 로고    scopus 로고
    • Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice
    • Luk, K.C., Kehm, V., Carroll, J., Zhang, B., O'Brien, P., Trojanowski, J.Q., Lee, V.M., Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice. Science 338 (2012), 949–953.
    • (2012) Science , vol.338 , pp. 949-953
    • Luk, K.C.1    Kehm, V.2    Carroll, J.3    Zhang, B.4    O'Brien, P.5    Trojanowski, J.Q.6    Lee, V.M.7
  • 41
    • 84961266899 scopus 로고    scopus 로고
    • Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers
    • Fraser, K.B., Moehle, M.S., Alcalay, R.N., West, A.B., LRRK2 Cohort Consortium. Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers. Neurology 86 (2016), 994–999.
    • (2016) Neurology , vol.86 , pp. 994-999
    • Fraser, K.B.1    Moehle, M.S.2    Alcalay, R.N.3    West, A.B.4
  • 42
    • 84991272394 scopus 로고    scopus 로고
    • Ser(P)-1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson's disease
    • Fraser, K.B., Rawlins, A.B., Clark, R.G., Alcalay, R.N., Standaert, D.G., Liu, N., West, A.B., Parkinson's Disease Biomarker Program Consortium. Ser(P)-1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson's disease. Mov. Disord. 31 (2016), 1543–1550.
    • (2016) Mov. Disord. , vol.31 , pp. 1543-1550
    • Fraser, K.B.1    Rawlins, A.B.2    Clark, R.G.3    Alcalay, R.N.4    Standaert, D.G.5    Liu, N.6    West, A.B.7
  • 44
    • 84994357526 scopus 로고    scopus 로고
    • Leucine-rich repeat kinase 2 influences fate decision of human monocytes differentiated from induced pluripotent stem cells
    • Speidel, A., Felk, S., Reinhardt, P., Sterneckert, J., Gillardon, F., Leucine-rich repeat kinase 2 influences fate decision of human monocytes differentiated from induced pluripotent stem cells. PLoS ONE, 11, 2016, e0165949.
    • (2016) PLoS ONE , vol.11 , pp. e0165949
    • Speidel, A.1    Felk, S.2    Reinhardt, P.3    Sterneckert, J.4    Gillardon, F.5
  • 47
    • 72149087091 scopus 로고    scopus 로고
    • Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein
    • Lin, X., Parisiadou, L., Gu, X.L., Wang, L., Shim, H., Sun, L., Xie, C., Long, C.X., Yang, W.J., Ding, J., et al. Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein. Neuron 64 (2009), 807–827.
    • (2009) Neuron , vol.64 , pp. 807-827
    • Lin, X.1    Parisiadou, L.2    Gu, X.L.3    Wang, L.4    Shim, H.5    Sun, L.6    Xie, C.7    Long, C.X.8    Yang, W.J.9    Ding, J.10
  • 49
    • 84891776413 scopus 로고    scopus 로고
    • Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies
    • Skibinski, G., Nakamura, K., Cookson, M.R., Finkbeiner, S., Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies. J. Neurosci. 34 (2014), 418–433.
    • (2014) J. Neurosci. , vol.34 , pp. 418-433
    • Skibinski, G.1    Nakamura, K.2    Cookson, M.R.3    Finkbeiner, S.4
  • 51
    • 84944865481 scopus 로고    scopus 로고
    • Heterogeneity of leucine-rich repeat kinase 2 mutations: genetics, mechanisms and therapeutic implications
    • Rudenko, I.N., Cookson, M.R., Heterogeneity of leucine-rich repeat kinase 2 mutations: genetics, mechanisms and therapeutic implications. Neurotherapeutics 11 (2014), 738–750.
    • (2014) Neurotherapeutics , vol.11 , pp. 738-750
    • Rudenko, I.N.1    Cookson, M.R.2
  • 54
    • 84921996531 scopus 로고    scopus 로고
    • Antisense oligonucleotide-based therapies for diseases caused by pre-mRNA processing defects
    • Rigo, F., Seth, P.P., Bennett, C.F., Antisense oligonucleotide-based therapies for diseases caused by pre-mRNA processing defects. Adv. Exp. Med. Biol. 825 (2014), 303–352.
    • (2014) Adv. Exp. Med. Biol. , vol.825 , pp. 303-352
    • Rigo, F.1    Seth, P.P.2    Bennett, C.F.3
  • 55
    • 84907033533 scopus 로고    scopus 로고
    • Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates
    • Volpicelli-Daley, L.A., Luk, K.C., Lee, V.M., Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite-like aggregates. Nat. Protoc. 9 (2014), 2135–2146.
    • (2014) Nat. Protoc. , vol.9 , pp. 2135-2146
    • Volpicelli-Daley, L.A.1    Luk, K.C.2    Lee, V.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.