Modulating Cytotoxic Effector Functions by Fc Engineering to Improve Cancer Therapy

Transfusion Medicine and Hemotherapy

Volumn 44, Issue 5, 2017, Pages 327-336

  Kellner, Christian ^a   Otte, Anna ^a   Cappuzzello, Elisa ^b   Klausz, Katja ^a   Peipp, Matthias ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

ADCC; Antibody engineering; CDC

Indexed keywords

ATEZOLIZUMAB; BI 836826; IMMUNOGLOBULIN FC FRAGMENT; INEBILIZUMAB; JNJ 56022473; LUMRETUZUMAB; MARGETUXIMAB; MOGAMULIZUMAB; MOR 208; OBINUTUZUMAB; PANKOMAB GEX; RITUXIMAB; TALACOTUZUMAB; TECENRIQ; TOMUZOTUXIMAB; UBLITUXIMAB; UNCLASSIFIED DRUG; XMAB 5574;

ANTIBODY AFFINITY; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ANTIBODY DEPENDENT CELLULAR PHAGOCYTOSIS; BIOENGINEERING; CANCER THERAPY; COMPLEMENT DEPENDENT CYTOTOXICITY; DNA MODIFICATION; DRUG CYTOTOXICITY; DRUG EFFICACY; FUCOSYLATION; GLYCO ENGINEERING; GLYCOSYLATION; IMMUNOCYTOTOXICITY; LYMPHATIC LEUKEMIA; NONHUMAN; PROCESS OPTIMIZATION; PROTEIN ENGINEERING; REVIEW; TRANSLATIONAL RESEARCH;

EID: 85028982223     PISSN: 16603796     EISSN: 16603818     Source Type: Journal    
DOI: 10.1159/000479980     Document Type: Review

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