메뉴 건너뛰기




Volumn 23, Issue 8, 2017, Pages 1886-1890

Atezolizumab: A PD-L1-blocking antibody for bladder cancer

Author keywords

[No Author keywords available]

Indexed keywords

ATEZOLIZUMAB; BCG VACCINE; CARBOPLATIN; CXCL11 CHEMOKINE; DOCETAXEL; GAMMA INTERFERON; GEMCITABINE; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 18; JANUS KINASE 3; LIVER ENZYME; PACLITAXEL; PLATINUM; PROGRAMMED DEATH 1 RECEPTOR; VINFLUNINE; ANTINEOPLASTIC AGENT; CD274 PROTEIN, HUMAN; MONOCLONAL ANTIBODY; PROGRAMMED DEATH 1 LIGAND 1;

EID: 85018853350     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-16-1417     Document Type: Article
Times cited : (183)

References (26)
  • 2
    • 79953306651 scopus 로고    scopus 로고
    • Identification of a soluble form of B7-H1 that retains immunosuppressive activity and is associated with aggressive renal cell carcinoma
    • Frigola X, Inman BA, Lohse CM, Krco CJ, Cheville JC, Thompson RH, et al. Identification of a soluble form of B7-H1 that retains immunosuppressive activity and is associated with aggressive renal cell carcinoma. Clin Cancer Res 2011;17:1915-23.
    • (2011) Clin Cancer Res , vol.17 , pp. 1915-1923
    • Frigola, X.1    Inman, B.A.2    Lohse, C.M.3    Krco, C.J.4    Cheville, J.C.5    Thompson, R.H.6
  • 3
    • 84959865627 scopus 로고    scopus 로고
    • Regulation of PD-L1: A novel role of prosurvival signalling in cancer
    • Chen J, Jiang CC, Jin L, Zhang XD. Regulation of PD-L1: a novel role of prosurvival signalling in cancer. Ann Oncol 2016;27:409-16.
    • (2016) Ann Oncol , vol.27 , pp. 409-416
    • Chen, J.1    Jiang, C.C.2    Jin, L.3    Zhang, X.D.4
  • 4
    • 34247113727 scopus 로고    scopus 로고
    • PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCGinduced granulomata: Associations with localized stage progression
    • Inman BA, Sebo TJ, Frigola X, Dong H, Bergstralh EJ, Frank I, et al. PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCGinduced granulomata: associations with localized stage progression. Cancer 2007;109:1499-505.
    • (2007) Cancer , vol.109 , pp. 1499-1505
    • Inman, B.A.1    Sebo, T.J.2    Frigola, X.3    Dong, H.4    Bergstralh, E.J.5    Frank, I.6
  • 5
    • 34248586083 scopus 로고    scopus 로고
    • Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers
    • Nakanishi J, Wada Y, Matsumoto K, Azuma M, Kikuchi K, Ueda S. Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers. Cancer Immunol Immunother 2007;56:1173-82.
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 1173-1182
    • Nakanishi, J.1    Wada, Y.2    Matsumoto, K.3    Azuma, M.4    Kikuchi, K.5    Ueda, S.6
  • 6
    • 51049096135 scopus 로고    scopus 로고
    • T-cell coregulatory molecule expression in urothelial cell carcinoma: Clinicopathologic correlations and association with survival
    • Boorjian SA, Sheinin Y, Crispen PL, Farmer SA, Lohse CM, Kuntz SM, et al. T-cell coregulatory molecule expression in urothelial cell carcinoma: clinicopathologic correlations and association with survival. Clin Cancer Res 2008;14:4800-8.
    • (2008) Clin Cancer Res , vol.14 , pp. 4800-4808
    • Boorjian, S.A.1    Sheinin, Y.2    Crispen, P.L.3    Farmer, S.A.4    Lohse, C.M.5    Kuntz, S.M.6
  • 7
    • 84961664582 scopus 로고    scopus 로고
    • Preclinical pharmacokinetics, pharmacodynamics, tissue distribution, and tumor penetration of anti-PD-L1 monoclonal antibody, an immune checkpoint inhibitor
    • Deng R, Bumbaca D, Pastuskovas CV, Boswell CA, West D, Cowan KJ, et al. Preclinical pharmacokinetics, pharmacodynamics, tissue distribution, and tumor penetration of anti-PD-L1 monoclonal antibody, an immune checkpoint inhibitor. mAbs 2016;8:593-603.
    • (2016) MAbs , vol.8 , pp. 593-603
    • Deng, R.1    Bumbaca, D.2    Pastuskovas, C.V.3    Boswell, C.A.4    West, D.5    Cowan, K.J.6
  • 8
    • 84920956735 scopus 로고    scopus 로고
    • Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
    • Herbst RS, Soria JC, Kowanetz M, Fine GD, Hamid O, Gordon MS, et al. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature 2014;515:563-7.
    • (2014) Nature , vol.515 , pp. 563-567
    • Herbst, R.S.1    Soria, J.C.2    Kowanetz, M.3    Fine, G.D.4    Hamid, O.5    Gordon, M.S.6
  • 9
    • 84923078390 scopus 로고    scopus 로고
    • MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
    • Powles T, Eder JP, Fine GD, Braiteh FS, Loriot Y, Cruz C, et al. MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer. Nature 2014;515:558-62.
    • (2014) Nature , vol.515 , pp. 558-562
    • Powles, T.1    Eder, J.P.2    Fine, G.D.3    Braiteh, F.S.4    Loriot, Y.5    Cruz, C.6
  • 10
    • 84947287356 scopus 로고    scopus 로고
    • A phase Ia study of MPDL3280A (anti-PDL1): Updated response and survival data in urothelial bladder cancer (UBC)
    • (suppl; abstr 4501)
    • Petrylack DP, Powles T, Bellmunt J, Braiteh F, Loriot Y, Zambrano C, et al. A phase Ia study of MPDL3280A (anti-PDL1): updated response and survival data in urothelial bladder cancer (UBC). J Clin Oncol 33, 2015 (suppl; abstr 4501).
    • (2015) J Clin Oncol , vol.33
    • Petrylack, D.P.1    Powles, T.2    Bellmunt, J.3    Braiteh, F.4    Loriot, Y.5    Zambrano, C.6
  • 11
    • 84959577118 scopus 로고    scopus 로고
    • Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: A single-arm, multicentre, phase 2 trial
    • Rosenberg JE, Hoffman-Censits J, Powles T, van der Heijden MS, Balar AV, Necchi A, et al. Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial. Lancet 2016;387:1909-20.
    • (2016) Lancet , vol.387 , pp. 1909-1920
    • Rosenberg, J.E.1    Hoffman-Censits, J.2    Powles, T.3    Van Der Heijden, M.S.4    Balar, A.V.5    Necchi, A.6
  • 12
    • 84982794411 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration, Silver Spring, MD: U.S. Food and Drug Administration; [cited 2016 Aug 21]
    • U.S. Food and Drug Administration. FDA approves new, targeted treatment for bladder cancer. Silver Spring, MD: U.S. Food and Drug Administration; 2016[cited 2016 Aug 21]. Available from: http://www.fda.gov/ NewsEvents/Newsroom/PressAnnouncements/ucm501762.htm.
    • (2016) FDA Approves New, Targeted Treatment for Bladder Cancer
  • 13
    • 84991202610 scopus 로고    scopus 로고
    • Atezolizumab (atezo) as first-line (1L) therapy in cisplatin-ineligible locally advanced/metastatic urothelial carcinoma (mUC): Primary analysis of IMvigor210 cohort 1
    • (suppl; abstr LBA4500)
    • Balar AV, Galsky MD, Loriot Y, Dawson NA, Necchi A, Srinivas S, et al. Atezolizumab (atezo) as first-line (1L) therapy in cisplatin-ineligible locally advanced/metastatic urothelial carcinoma (mUC): primary analysis of IMvigor210 cohort 1. J Clin Oncol 34, 2016 (suppl; abstr LBA4500).
    • (2016) J Clin Oncol , vol.34
    • Balar, A.V.1    Galsky, M.D.2    Loriot, Y.3    Dawson, N.A.4    Necchi, A.5    Srinivas, S.6
  • 14
    • 84896329384 scopus 로고    scopus 로고
    • Six-month progression-free survival as the primary endpoint to evaluate the activity of new agents as second-line therapy for advanced urothelial carcinoma
    • Agarwal N, Bellmunt J, Maughan BL, Boucher KM, Choueiri TK, Qu AQ, et al. Six-month progression-free survival as the primary endpoint to evaluate the activity of new agents as second-line therapy for advanced urothelial carcinoma. Clin Genitourin Cancer 2014;12:130-7.
    • (2014) Clin Genitourin Cancer , vol.12 , pp. 130-137
    • Agarwal, N.1    Bellmunt, J.2    Maughan, B.L.3    Boucher, K.M.4    Choueiri, T.K.5    Qu, A.Q.6
  • 15
    • 84855583390 scopus 로고    scopus 로고
    • Randomized phase II/III trial assessing gemcitabine/carboplatin and methotrexate/carboplatin/vinblastine in patients with advanced urothelial cancer who are unfit for cisplatin-based chemotherapy: EORTC study 30986
    • De Santis M, Bellmunt J, Mead G, Kerst JM, Leahy M, Maroto P, et al. Randomized phase II/III trial assessing gemcitabine/carboplatin and methotrexate/carboplatin/vinblastine in patients with advanced urothelial cancer who are unfit for cisplatin-based chemotherapy: EORTC study 30986. J Clin Oncol 2012;30:191-9.
    • (2012) J Clin Oncol , vol.30 , pp. 191-199
    • De Santis, M.1    Bellmunt, J.2    Mead, G.3    Kerst, J.M.4    Leahy, M.5    Maroto, P.6
  • 16
    • 84953837254 scopus 로고    scopus 로고
    • Second line chemotherapy for advanced and metastatic urothelial carcinoma: Vinflunine and beyond-A comprehensive review of the current literature
    • Oing C, RinkM, Oechsle K, Seidel C, von AmsbergG, Bokemeyer C. Second line chemotherapy for advanced and metastatic urothelial carcinoma: vinflunine and beyond-A comprehensive review of the current literature. J Urol 2016;195:254-63.
    • (2016) J Urol , vol.195 , pp. 254-263
    • Oing, C.1    Rink, M.2    Oechsle, K.3    Seidel, C.4    Von Amsberg, G.5    Bokemeyer, C.6
  • 17
    • 84969710115 scopus 로고    scopus 로고
    • Managing immune checkpoint-blocking antibody side effects
    • Postow MA. Managing immune checkpoint-blocking antibody side effects. Am Soc Clin Oncol Educ Book 2015:76-83.
    • (2015) Am Soc Clin Oncol Educ Book , pp. 76-83
    • Postow, M.A.1
  • 18
    • 84975728236 scopus 로고    scopus 로고
    • Management of toxicities of immune checkpoint inhibitors
    • Spain L, Diem S, Larkin J. Management of toxicities of immune checkpoint inhibitors. Cancer Treat Rev 2016;44:51-60.
    • (2016) Cancer Treat Rev , vol.44 , pp. 51-60
    • Spain, L.1    Diem, S.2    Larkin, J.3
  • 19
    • 84939227614 scopus 로고    scopus 로고
    • Differential activity of nivolumab, pembrolizumab and MPDL3280A according to the tumor expression of programmed death-ligand-1 (PDL1): Sensitivity analysis of trials in melanoma, lung and genitourinary cancers
    • Carbognin L, Pilotto S, Milella M, Vaccaro V, Brunelli M, Calio A, et al. Differential activity of nivolumab, pembrolizumab and MPDL3280A according to the tumor expression of programmed death-ligand-1 (PDL1): sensitivity analysis of trials in melanoma, lung and genitourinary cancers. PLoS One 2015;10:e0130142.
    • (2015) PLoS One , vol.10 , pp. e0130142
    • Carbognin, L.1    Pilotto, S.2    Milella, M.3    Vaccaro, V.4    Brunelli, M.5    Calio, A.6
  • 20
    • 84892544676 scopus 로고    scopus 로고
    • Association of T-cell co-regulatory protein expression with clinical outcomes following radical cystectomy for urothelial carcinoma of the bladder
    • Xylinas E, Robinson BD, Kluth LA, Volkmer BG, Hautmann R, Kufer R, et al. Association of T-cell co-regulatory protein expression with clinical outcomes following radical cystectomy for urothelial carcinoma of the bladder. Eur J Surg Oncol 2014;40:121-7.
    • (2014) Eur J Surg Oncol , vol.40 , pp. 121-127
    • Xylinas, E.1    Robinson, B.D.2    Kluth, L.A.3    Volkmer, B.G.4    Hautmann, R.5    Kufer, R.6
  • 21
    • 84904024273 scopus 로고    scopus 로고
    • Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy
    • Taube JM, Klein A, Brahmer JR, Xu H, Pan X, Kim JH, et al. Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy. Clin Cancer Res 2014;20: 5064-74.
    • (2014) Clin Cancer Res , vol.20 , pp. 5064-5074
    • Taube, J.M.1    Klein, A.2    Brahmer, J.R.3    Xu, H.4    Pan, X.5    Kim, J.H.6
  • 22
    • 84962497081 scopus 로고    scopus 로고
    • Atezolizumab, an anti-programmed death-ligand 1 antibody, in metastatic renal cell carcinoma: Long-term safety, clinical activity, and immune correlates from a phase Ia study
    • McDermott DF, Sosman JA, Sznol M, Massard C, Gordon MS, Hamid O, et al. Atezolizumab, an anti-programmed death-ligand 1 antibody, in metastatic renal cell carcinoma: long-term safety, clinical activity, and immune correlates from a phase Ia study. J Clin Oncol 2016;34:833-42.
    • (2016) J Clin Oncol , vol.34 , pp. 833-842
    • McDermott, D.F.1    Sosman, J.A.2    Sznol, M.3    Massard, C.4    Gordon, M.S.5    Hamid, O.6
  • 23
    • 84962038946 scopus 로고    scopus 로고
    • Atezolizumab versus docetaxel for patientswith previously treated non-small-cell lung cancer (POPLAR): A multicentre, open-label, phase 2 randomised controlled trial
    • Fehrenbacher L, Spira A, Ballinger M, Kowanetz M, Vansteenkiste J, Mazieres J, et al. Atezolizumab versus docetaxel for patientswith previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial. Lancet 2016;387:1837-46.
    • (2016) Lancet , vol.387 , pp. 1837-1846
    • Fehrenbacher, L.1    Spira, A.2    Ballinger, M.3    Kowanetz, M.4    Vansteenkiste, J.5    Mazieres, J.6
  • 26
    • 84975292831 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy for muscle-invasive bladder cancer: A systematic review and two-step meta-analysis
    • Yin M, Joshi M, Meijer RP, Glantz M, Holder S, Harvey HA, et al. Neoadjuvant chemotherapy for muscle-invasive bladder cancer: a systematic review and two-step meta-analysis. Oncologist 2016;21:708-15.
    • (2016) Oncologist , vol.21 , pp. 708-715
    • Yin, M.1    Joshi, M.2    Meijer, R.P.3    Glantz, M.4    Holder, S.5    Harvey, H.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.