In vitro and in silico studies of mangiferin from aphloia theiformis on key enzymes linked to diabetes type 2 and associated complications

Medicinal Chemistry

Volumn 13, Issue 7, 2017, Pages 633-640

  Picot, Marie C N ^a   Zengin, Gokhan ^b   Mollica, Adriano ^c   Stefanucci, Azzurra ^c   Carradori, Simone ^c   Mahomoodally, Mohamad F ^a  

^a UNIVERSITY OF MAURITIUS   (Mauritius)

^b SELCUK UNIVERSITY   (Turkey)

^c UNIVERSITY OF CHIETI   (Italy)

Author keywords

Aphloia theiformis; Diabetes type 2; Mangiferin; Molecular docking; Natural enzyme inhibitor; Obesity.

Indexed keywords

ACETIC ACID ETHYL ESTER; ACETYLCHOLINESTERASE; ALPHA GLUCOSIDASE; AMYLASE; BUTANOL; CHOLESTEROL ESTERASE; DIPEPTIDYL CARBOXYPEPTIDASE; ENZYME; GLYCOGEN PHOSPHORYLASE; MANGIFERIN; METHANOL; PARAOXON; PLANT EXTRACT; TRIACYLGLYCEROL LIPASE; TRYPTOPHAN; UREASE; HYDROLASE; XANTHONE DERIVATIVE;

ALLOSTERIC SITE; ALZHEIMER DISEASE; APHLOIA THEIFORMIS; ARTICLE; CATALYSIS; COMPUTER MODEL; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DIABETIC COMPLICATION; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG PROTEIN BINDING; ENZYME STRUCTURE; HYDROGEN BOND; HYPERTENSION; IN VITRO STUDY; MOLECULAR DOCKING; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; SALICACEAE; UROLITHIASIS; ANIMAL; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; FABACEAE; HUMAN; KINETICS; PIG; VASCULAR PLANT;

ALLOSTERIC SITE; ANIMALS; CATALYTIC DOMAIN; DIABETES MELLITUS, TYPE 2; FABACEAE; GLYCOGEN PHOSPHORYLASE; HUMANS; HYDROGEN BONDING; HYDROLASES; KINETICS; MOLECULAR DOCKING SIMULATION; PARAOXON; SWINE; TRACHEOPHYTA; XANTHONES;

EID: 85028932381     PISSN: 15734064     EISSN: 18756638     Source Type: Journal    
DOI: 10.2174/1573406413666170307163929     Document Type: Article

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