Screening of traditional antidiabetic medicinal plants of Mauritius for possible α-amylase inhibitory effects in vitro

Phytotherapy Research

Volumn 20, Issue 3, 2006, Pages 228-231

  Kotowaroo, M I ^a   Mahomoodally, M F ^a   Gurib Fakim, A ^a   Subratty, A H ^a  

^a UNIVERSITY OF MAURITIUS   (Mauritius)

Author keywords

Artocarpus heterophyllus; Diabetes; Enzyme kinetics; Mauritius; Starch blockers; Traditional medicine

Indexed keywords

AMYLASE; AMYLASE INHIBITOR; ANTIDIABETIC AGENT; ARTOCARPUS HETEROPHYLLUS EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

AEGLE; AEGLE MARMELOS; AQUEOUS SOLUTION; ARTICLE; ARTOCARPUS HETEROPHYLLUS; AZADIRACHTA INDICA; BREADFRUIT; CALCULATION; COIX; COIX LACRYMA JOBI; COMPETITIVE INHIBITION; CONTROLLED STUDY; DIABETES MELLITUS; DRUG EFFECT; DRUG SCREENING; ENZYME INHIBITION; ENZYME KINETICS; LINEWEAVER BURK CALCULATION; LOQUAT; MALE; MAURITIUS; MEDICINAL PLANT; MICHAELIS CONSTANT; MICHAELIS MENTEN KINETICS; NONHUMAN; PLANT LEAF; PLASMA; RAT; SYZYGIUM CUMINI; TRADITIONAL MEDICINE; VANGUERIA MADAGASCARIENSIS;

ALPHA-AMYLASE; ANGIOSPERMS; ANIMALS; ARTOCARPUS; ENZYME INHIBITORS; HYPOGLYCEMIC AGENTS; MALE; MAURITIUS; PLANT EXTRACTS; PLANT LEAVES; PLANTS; PLANTS, MEDICINAL; RATS; WATER;

AEGLE MARMELOS; ARTOCARPUS ALTILIS; ARTOCARPUS HETEROPHYLLUS; AZADIRACHTA INDICA; COIX; COIX LACRYMA-JOBI; ERIOBOTRYA JAPONICA; MELIACEAE; MORACEAE; MYRTACEAE; POACEAE; ROSACEAE; RUBIACEAE; RUTACEAE; SYZYGIUM CUMINI; VANGUERIA EDULIS;

EID: 33645462318     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.1839     Document Type: Article

References (10)

1. Deshpande SS, Sathe SK, Salunkhe DK, Cornforth DP. 1982. Effects of dehulling on phytic acid, polyphenols and enzyme inhibitors of dry beans (Phaseolus vulgaris L). J Food Sci 47: 1846-1850.
2. Gurib-Fakim A, Gueho J, Bissoondoyal MD. 1996. Plantes Medicinales de Maurice, 2. Editions de l'Ocean Indien: Rose Hill, Maurice, 440-441.
3. Kobayashi K, Funayama N, Suzuki R, Yoshizaki F. 2002. Survey of the influence of Chinese medicinal prescriptions on amylase activity in mouse plasma and gastrointestinal tube. Biol Pharm Bull 25: 1108-1111.
4. Mahomoodally MF, Gurib-Fakim A, Subratty AH. 2004. Momordica charantia extracts inhibit uptake of monosaccharide and amino acid across rat everted gut sacs in-vitro. Biol Pharm Bull 27: 216-218.
5. Mahomoodally MF, Gurib-Fakim A, Subratty AH. 2005. Experimental evidence for in vitro fluid transport in the presence of a traditional medicinal fruit extract across rat everted intestinal sacs. Fund Clin Pharm 19: 87-92.
6. Mao W, Kinsella J. 1981. Amylase activity in banana fruit: properties and changes in activity with ripening. J Food Sci 46: 436-440.
7. Mooradian AD, Thurman J. 1999. Drug therapy of post prandial hyperglycaemia. Drugs 57: 19-29.
8. Puls W, Keup U. 1973. Influence of an alpha amylase inhibitor (BAY d 7791) on blood glucose, serum insulin and NEFA in starch loading tests in rats, dogs and man. Diabetologia 9: 97-101.
9. Rang HP, Dale MM, Ritter JM. 1999. Pharmacology, 4th edn, Elsevier Science. UK, 100-150.
10. Tiwari A, Madhusudana R. 2002. Diabetes mellitus and multiple therapeutic approaches of phytochemicals: Present status and future prospects. Curr Sci 83: 30-38.