Structural characterization of angiotensin I-converting enzyme in complex with a selenium analogue of captopril

FEBS Journal

Volumn 278, Issue 19, 2011, Pages 3644-3650

  Akif, Mohd ^a   Masuyer, Geoffrey ^a   Schwager, Sylva L U ^b   Bhuyan, Bhaskar J ^c   Mugesh, Govindasamy ^c   Isaac, R Elwyn ^d   Sturrock, Edward D ^b   Acharya, K Ravi ^a  

^a University of Bath   (United Kingdom)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c INDIAN INSTITUTE OF SCIENCE   (India)

^d UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

angiotensin I converting enzyme (ACE); cardiovascular disease; inhibitor design; metalloprotease; selenium

Indexed keywords

CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE; SELENIUM DERIVATIVE; SELENOLATE; UNCLASSIFIED DRUG; ZINC ION;

ANIMAL CELL; ANTIHYPERTENSIVE ACTIVITY; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DROSOPHILA MELANOGASTER; DRUG BINDING SITE; DRUG EFFECT; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME STRUCTURE; FEMALE; HAMSTER; IC 50; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; REVIEW; STRUCTURE ANALYSIS;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; CAPTOPRIL; CATALYTIC DOMAIN; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; HUMANS; MALE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PEPTIDYL-DIPEPTIDASE A; PROTEIN CONFORMATION; SELENIUM; TESTIS; X-RAY DIFFRACTION;

DROSOPHILA MELANOGASTER;

EID: 80052966095     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08276.x     Document Type: Review

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