Revisiting the latency of uridine diphosphate-glucuronosyltransferases (UGTs)-how doethe endoplasmic reticulum membrane influence their function?

Pharmaceutics

Volumn 9, Issue 3, 2017, Pages

  Liu, Yuejian ^a   Coughtrie, Michael W H ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Glucuronidation; Latency; Microsomes; References; Regulation; UDP glucuronosyltransferase

Indexed keywords

ADENINE NUCLEOTIDE; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A6; MEMBRANE PROTEIN; PHOSPHOLIPID;

ALLOSTERISM; CELL COMPARTMENTALIZATION; CONFORMATIONAL TRANSITION; DETOXIFICATION; DRUG CLEARANCE; ENDOPLASMIC RETICULUM MEMBRANE; ENZYME CONFORMATION; ENZYME LOCALIZATION; GLUCURONIDATION; HUMAN; INTRACELLULAR TRANSPORT; LIPID RAFT; LIVER MICROSOME; MEMBRANE COMPONENT; MEMBRANE DAMAGE; MICROSOME MEMBRANE; NONHUMAN; PROTEIN LIPID INTERACTION; REVIEW;

EID: 85028632740     PISSN: None     EISSN: 19994923     Source Type: Journal    
DOI: 10.3390/pharmaceutics9030032     Document Type: Review

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