Molecular cloning of the baboon UDP-glucuronosyltransferase 1A gene family: Evolution of the primate UGT1 locus and relevance for models of human drug metabolism

Pharmacogenetics and Genomics

Volumn 17, Issue 1, 2007, Pages 11-24

  Caspersen, Casper S ^a   Reznik, Boris ^a   Weldy, Piper L ^a   Abildskov, Kirsten M ^a   Stark, Raymond I ^a   Garland, Marianne ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Baboon UGT1A; Bilirubin; Evolution; Glucuronidation; Phylogenetic tree

Indexed keywords

BILIRUBIN; BUPRENORPHINE; COMPLEMENTARY DNA; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A; GLUCURONOSYLTRANSFERASE 1A10; GLUCURONOSYLTRANSFERASE 1A11; GLUCURONOSYLTRANSFERASE 1A12; GLUCURONOSYLTRANSFERASE 1A13; GLUCURONOSYLTRANSFERASE 1A2; GLUCURONOSYLTRANSFERASE 1A3; GLUCURONOSYLTRANSFERASE 1A4; GLUCURONOSYLTRANSFERASE 1A5; GLUCURONOSYLTRANSFERASE 1A7; GLUCURONOSYLTRANSFERASE 1A8; GLUCURONOSYLTRANSFERASE 1A9; PARACETAMOL; SEROTONIN; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ANIMAL TISSUE; ARTICLE; BABOON; BIOLOGICAL MODEL; CONTROLLED STUDY; DRUG GLUCURONIDATION; DRUG METABOLISM; EMBRYO; EXON; FETUS; GENE DUPLICATION; GENE LOCUS; GENE REARRANGEMENT; GENETIC VARIABILITY; GLUCURONIDATION; HUMAN; HUMAN CELL; HUMAN VERSUS ANIMAL COMPARISON; MOLECULAR CLONING; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PHYLOGENY; PRIMATE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BILIRUBIN; CLONING, MOLECULAR; CONSERVED SEQUENCE; CRIGLER-NAJJAR SYNDROME; EVOLUTION, MOLECULAR; GLUCURONOSYLTRANSFERASE; HUMANS; MODELS, ANIMAL; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PAPIO; PHARMACOGENETICS; PHYLOGENY; SEQUENCE ALIGNMENT;

PAPIO; PRIMATES;

EID: 33846687370     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/01.fpc.0000236323.96056.d8     Document Type: Article

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