IL-7 restores t lymphocyte immunometabolic failure in septic shock patients through mtor activation

Journal of Immunology

Volumn 199, Issue 5, 2017, Pages 1606-1615

  Venet, Fabienne ^a   Demaret, Julie ^a   Blaise, Benjamin J ^b   Rouget, Christelle ^a   Girardot, Thibaut ^a   Idealisoa, Estellie ^a   Rimmele, Thomas ^a   Mallet, Francois ^a   Lepape, Alain ^c   Textoris, Julien ^a   Monneret, Guillaume ^a  

^a EDOUARD HERRIOT HOSPITAL   (France)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c CENTRE HOSPITALIER LYON SUD   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; GLUCOSE TRANSPORTER 1; INTERLEUKIN 7; MTOR PROTEIN, HUMAN; RAPAMYCIN; SLC2A1 PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

AGED; CELL CULTURE; CELL PROLIFERATION; DRUG EFFECTS; ENERGY METABOLISM; FEMALE; GENETICS; GLYCOLYSIS; HUMAN; IMMUNOLOGY; IMMUNOTHERAPY; MALE; METABOLISM; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE; OXIDATIVE PHOSPHORYLATION; PROCEDURES; SHOCK, SEPTIC; T LYMPHOCYTE; VERY ELDERLY;

ADENOSINE TRIPHOSPHATE; AGED; AGED, 80 AND OVER; CELL PROLIFERATION; CELLS, CULTURED; ENERGY METABOLISM; FEMALE; GLUCOSE; GLUCOSE TRANSPORTER TYPE 1; GLYCOLYSIS; HUMANS; IMMUNOTHERAPY; INTERLEUKIN-7; MALE; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXIDATIVE PHOSPHORYLATION; SHOCK, SEPTIC; SIROLIMUS; T-LYMPHOCYTES; TOR SERINE-THREONINE KINASES;

EID: 85027982774     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1700127     Document Type: Article

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