-
1
-
-
33750047495
-
Management of Sepsis
-
10.1056/NEJMra043632, 17050894
-
Russell JA. Management of Sepsis. New Engl J Med 2006, 355:1699-1713. 10.1056/NEJMra043632, 17050894.
-
(2006)
New Engl J Med
, vol.355
, pp. 1699-1713
-
-
Russell, J.A.1
-
2
-
-
0037180768
-
The immunopathogenesis of sepsis
-
10.1038/nature01326, 12490963
-
Cohen J. The immunopathogenesis of sepsis. Nature 2002, 420:885-891. 10.1038/nature01326, 12490963.
-
(2002)
Nature
, vol.420
, pp. 885-891
-
-
Cohen, J.1
-
3
-
-
0030843156
-
Sepsis: a new hypothesis for pathogenesis of the disease process
-
10.1378/chest.112.1.235, 9228382
-
Bone RC, Grodzin CJ, Balk RA. Sepsis: a new hypothesis for pathogenesis of the disease process. Chest 1997, 112:235-243. 10.1378/chest.112.1.235, 9228382.
-
(1997)
Chest
, vol.112
, pp. 235-243
-
-
Bone, R.C.1
Grodzin, C.J.2
Balk, R.A.3
-
4
-
-
0036213966
-
Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study
-
10.1007/s00134-001-1143-z, 11907653
-
Alberti C, Brun-Buisson C, Burchardi H, Martin C, Goodman S, Artigas A, Sicignano A, Palazzo M, Moreno R, Boulme R, Lepage E, Le Gall R. Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study. Intensive Care Med 2002, 28:108-121. 10.1007/s00134-001-1143-z, 11907653.
-
(2002)
Intensive Care Med
, vol.28
, pp. 108-121
-
-
Alberti, C.1
Brun-Buisson, C.2
Burchardi, H.3
Martin, C.4
Goodman, S.5
Artigas, A.6
Sicignano, A.7
Palazzo, M.8
Moreno, R.9
Boulme, R.10
Lepage, E.11
Le Gall, R.12
-
5
-
-
66749164669
-
The sepsis seesaw: tilting toward immunosuppression
-
10.1038/nm0509-496, 19424209
-
Hotchkiss RS, Coopersmith CM, McDunn JE, Ferguson TA. The sepsis seesaw: tilting toward immunosuppression. Nat Med 2009, 15:496-497. 10.1038/nm0509-496, 19424209.
-
(2009)
Nat Med
, vol.15
, pp. 496-497
-
-
Hotchkiss, R.S.1
Coopersmith, C.M.2
McDunn, J.E.3
Ferguson, T.A.4
-
6
-
-
47849130092
-
Cytomegalovirus reactivation in critically ill immunocompetent patients
-
10.1001/jama.300.4.413, 2774501, 18647984
-
Limaye AP, Kirby KA, Rubenfeld GD, Leisenring WM, Bulger EM, Neff MJ, Gibran NS, Huang ML, Santo Hayes TK, Corey L, Boeckh M. Cytomegalovirus reactivation in critically ill immunocompetent patients. JAMA 2008, 300:413-422. 10.1001/jama.300.4.413, 2774501, 18647984.
-
(2008)
JAMA
, vol.300
, pp. 413-422
-
-
Limaye, A.P.1
Kirby, K.A.2
Rubenfeld, G.D.3
Leisenring, W.M.4
Bulger, E.M.5
Neff, M.J.6
Gibran, N.S.7
Huang, M.L.8
Santo Hayes, T.K.9
Corey, L.10
Boeckh, M.11
-
7
-
-
0032770246
-
Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction
-
10.1097/00003246-199907000-00002, 10446814
-
Hotchkiss RS, Swanson PE, Freeman BD, Tinsley KW, Cobb JP, Matuschak GM, Buchman TG, Karl IE. Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction. Crit Care Med 1999, 27:1230-1251. 10.1097/00003246-199907000-00002, 10446814.
-
(1999)
Crit Care Med
, vol.27
, pp. 1230-1251
-
-
Hotchkiss, R.S.1
Swanson, P.E.2
Freeman, B.D.3
Tinsley, K.W.4
Cobb, J.P.5
Matuschak, G.M.6
Buchman, T.G.7
Karl, I.E.8
-
8
-
-
5944251623
-
Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte
-
10.1038/82741, 11101871
-
Hotchkiss RS, Chang KC, Swanson PE, Tinsley KW, Hui JJ, Klender P, Xanthoudakis S, Roy S, Black C, Grimm E, Aspiotis R, Han Y, Nicholson DW, Karl IE. Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte. Nat Immunol 2000, 1:496-501. 10.1038/82741, 11101871.
-
(2000)
Nat Immunol
, vol.1
, pp. 496-501
-
-
Hotchkiss, R.S.1
Chang, K.C.2
Swanson, P.E.3
Tinsley, K.W.4
Hui, J.J.5
Klender, P.6
Xanthoudakis, S.7
Roy, S.8
Black, C.9
Grimm, E.10
Aspiotis, R.11
Han, Y.12
Nicholson, D.W.13
Karl, I.E.14
-
9
-
-
0035338993
-
Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans
-
Hotchkiss RS, Tinsley KW, Swanson PE, Schmieg RE, Hui JJ, Chang KC, Osborne DF, Freeman BD, Cobb JP, Buchman TG, Karl IE. Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans. J Immunol 2001, 166:6952-6963.
-
(2001)
J Immunol
, vol.166
, pp. 6952-6963
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
Schmieg, R.E.4
Hui, J.J.5
Chang, K.C.6
Osborne, D.F.7
Freeman, B.D.8
Cobb, J.P.9
Buchman, T.G.10
Karl, I.E.11
-
10
-
-
0036499162
-
Depletion of dendritic cells, but not macrophages, in patients with sepsis
-
Hotchkiss RS, Tinsley KW, Swanson PE, Grayson MH, Osborne DF, Wagner TH, Cobb JP, Coopersmith C, Karl IE. Depletion of dendritic cells, but not macrophages, in patients with sepsis. J Immunol 2002, 168:2493-2500.
-
(2002)
J Immunol
, vol.168
, pp. 2493-2500
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
Grayson, M.H.4
Osborne, D.F.5
Wagner, T.H.6
Cobb, J.P.7
Coopersmith, C.8
Karl, I.E.9
-
11
-
-
0030917203
-
Monocyte deactivation in septic patients: restoration by IFN-gamma treatment
-
10.1038/nm0697-678, 9176497
-
Docke WD, Randow F, Syrbe U, Krausch D, Asadullah K, Reinke P, Volk HD, Kox W. Monocyte deactivation in septic patients: restoration by IFN-gamma treatment. Nat Med 1997, 3:678-681. 10.1038/nm0697-678, 9176497.
-
(1997)
Nat Med
, vol.3
, pp. 678-681
-
-
Docke, W.D.1
Randow, F.2
Syrbe, U.3
Krausch, D.4
Asadullah, K.5
Reinke, P.6
Volk, H.D.7
Kox, W.8
-
12
-
-
33747156889
-
Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock
-
10.1007/s00134-006-0204-8, 16741700
-
Monneret G, Lepape A, Voirin N, Bohe J, Venet F, Debard AL, Thizy H, Bienvenu J, Gueyffier F, Vanhems P. Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock. Intensive Care Med 2006, 32:1175-1183. 10.1007/s00134-006-0204-8, 16741700.
-
(2006)
Intensive Care Med
, vol.32
, pp. 1175-1183
-
-
Monneret, G.1
Lepape, A.2
Voirin, N.3
Bohe, J.4
Venet, F.5
Debard, A.L.6
Thizy, H.7
Bienvenu, J.8
Gueyffier, F.9
Vanhems, P.10
-
13
-
-
68949158556
-
Differential role for CD80 and CD86 in the regulation of the innate immune response in murine polymicrobial sepsis
-
10.1371/journal.pone.0006600, 2719911, 19672303
-
Nolan A, Kobayashi H, Naveed B, Kelly A, Hoshino Y, Hoshino S, Karulf MR, Rom WN, Weiden MD, Gold JA. Differential role for CD80 and CD86 in the regulation of the innate immune response in murine polymicrobial sepsis. PLoS One 2009, 4:e6600. 10.1371/journal.pone.0006600, 2719911, 19672303.
-
(2009)
PLoS One
, vol.4
-
-
Nolan, A.1
Kobayashi, H.2
Naveed, B.3
Kelly, A.4
Hoshino, Y.5
Hoshino, S.6
Karulf, M.R.7
Rom, W.N.8
Weiden, M.D.9
Gold, J.A.10
-
14
-
-
33847011663
-
The contribution of CD4+ CD25+ T-regulatory-cells to immune suppression in sepsis
-
10.1097/01.shk.0000239780.33398.e4, 1805637, 17304105
-
Wisnoski N, Chung CS, Chen Y, Huang X, Ayala A. The contribution of CD4+ CD25+ T-regulatory-cells to immune suppression in sepsis. Shock 2007, 27:251-257. 10.1097/01.shk.0000239780.33398.e4, 1805637, 17304105.
-
(2007)
Shock
, vol.27
, pp. 251-257
-
-
Wisnoski, N.1
Chung, C.S.2
Chen, Y.3
Huang, X.4
Ayala, A.5
-
15
-
-
84855444617
-
A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1
-
10.1172/JCI57990, 3248287, 22156198
-
Pillay J, Kamp VM, van Hoffen E, Visser T, Tak T, Lammers JW, Ulfman LH, Leenen LP, Pickkers P, Koenderman L. A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1. J Clin Invest 2012, 122:327-336. 10.1172/JCI57990, 3248287, 22156198.
-
(2012)
J Clin Invest
, vol.122
, pp. 327-336
-
-
Pillay, J.1
Kamp, V.M.2
van Hoffen, E.3
Visser, T.4
Tak, T.5
Lammers, J.W.6
Ulfman, L.H.7
Leenen, L.P.8
Pickkers, P.9
Koenderman, L.10
-
16
-
-
62949142070
-
Increased circulating regulatory T cells (CD4(+)CD25 (+)CD127 (-)) contribute to lymphocyte anergy in septic shock patients
-
10.1007/s00134-008-1337-8, 2789433, 18946659
-
Venet F, Chung CS, Kherouf H, Geeraert A, Malcus C, Poitevin F, Bohe J, Lepape A, Ayala A, Monneret G. Increased circulating regulatory T cells (CD4(+)CD25 (+)CD127 (-)) contribute to lymphocyte anergy in septic shock patients. Intensive Care Med 2009, 35:678-686. 10.1007/s00134-008-1337-8, 2789433, 18946659.
-
(2009)
Intensive Care Med
, vol.35
, pp. 678-686
-
-
Venet, F.1
Chung, C.S.2
Kherouf, H.3
Geeraert, A.4
Malcus, C.5
Poitevin, F.6
Bohe, J.7
Lepape, A.8
Ayala, A.9
Monneret, G.10
-
17
-
-
43349107987
-
Regulatory T cell populations in sepsis and trauma
-
Venet F, Chung C-S, Monneret G, Huang X, Horner B, Garber M, Ayala A. Regulatory T cell populations in sepsis and trauma. J Leukoc Biol 2008, 83:523-535.
-
(2008)
J Leukoc Biol
, vol.83
, pp. 523-535
-
-
Venet, F.1
Chung, C.-S.2
Monneret, G.3
Huang, X.4
Horner, B.5
Garber, M.6
Ayala, A.7
-
18
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. 2009, 9:162-174.
-
(2009)
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
19
-
-
34250359119
-
MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis
-
10.1084/jem.20062602, 2118626, 17548519
-
Delano MJ, Scumpia PO, Weinstein JS, Coco D, Nagaraj S, Kelly-Scumpia KM, O'Malley KA, Wynn JL, Antonenko S, Al-Quran SZ, Swan R, Chung CS, Atkinson MA, Ramphal R, Gabrilovich DI, Reeves WH, Ayala A, Phillips J, Laface D, Heyworth PG, Clare-Salzler M, Moldawer LL. MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J Exp Med 2007, 204:1463-1474. 10.1084/jem.20062602, 2118626, 17548519.
-
(2007)
J Exp Med
, vol.204
, pp. 1463-1474
-
-
Delano, M.J.1
Scumpia, P.O.2
Weinstein, J.S.3
Coco, D.4
Nagaraj, S.5
Kelly-Scumpia, K.M.6
O'Malley, K.A.7
Wynn, J.L.8
Antonenko, S.9
Al-Quran, S.Z.10
Swan, R.11
Chung, C.S.12
Atkinson, M.A.13
Ramphal, R.14
Gabrilovich, D.I.15
Reeves, W.H.16
Ayala, A.17
Phillips, J.18
Laface, D.19
Heyworth, P.G.20
Clare-Salzler, M.21
Moldawer, L.L.22
more..
-
20
-
-
84255194001
-
Immunosuppression in patients who die of sepsis and multiple organ failure
-
10.1001/jama.2011.1829, 3361243, 22187279
-
Boomer JS, To K, Chang KC, Takasu O, Osborne DF, Walton AH, Bricker TL, Jarman SD, Kreisel D, Krupnick AS, Srivastava A, Swanson PE, Green JM, Hotchkiss RS. Immunosuppression in patients who die of sepsis and multiple organ failure. JAMA 2011, 306:2594-2605. 10.1001/jama.2011.1829, 3361243, 22187279.
-
(2011)
JAMA
, vol.306
, pp. 2594-2605
-
-
Boomer, J.S.1
To, K.2
Chang, K.C.3
Takasu, O.4
Osborne, D.F.5
Walton, A.H.6
Bricker, T.L.7
Jarman, S.D.8
Kreisel, D.9
Krupnick, A.S.10
Srivastava, A.11
Swanson, P.E.12
Green, J.M.13
Hotchkiss, R.S.14
-
21
-
-
0027158798
-
Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells
-
10.1038/362758a0, 8469287
-
Moskophidis D, Lechner F, Pircher H, Zinkernagel RM. Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature 1993, 362:758-761. 10.1038/362758a0, 8469287.
-
(1993)
Nature
, vol.362
, pp. 758-761
-
-
Moskophidis, D.1
Lechner, F.2
Pircher, H.3
Zinkernagel, R.M.4
-
22
-
-
0037234857
-
T cells versus HIV-1: fighting exhaustion as well as escape
-
10.1038/ni0103-12, 12496971
-
Robinson HL. T cells versus HIV-1: fighting exhaustion as well as escape. Nat Immunol 2003, 4:12-13. 10.1038/ni0103-12, 12496971.
-
(2003)
Nat Immunol
, vol.4
, pp. 12-13
-
-
Robinson, H.L.1
-
23
-
-
1642415940
-
Maintenance, loss, and resurgence of T cell responses during acute, protracted, and chronic viral infections
-
Fuller MJ, Khanolkar A, Tebo AE, Zajac AJ. Maintenance, loss, and resurgence of T cell responses during acute, protracted, and chronic viral infections. J Immunol 2004, 172:4204-4214.
-
(2004)
J Immunol
, vol.172
, pp. 4204-4214
-
-
Fuller, M.J.1
Khanolkar, A.2
Tebo, A.E.3
Zajac, A.J.4
-
24
-
-
33750691709
-
PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion
-
10.1128/JVI.01177-06, 1642188, 16956940
-
Urbani S, Amadei B, Tola D, Massari M, Schivazappa S, Missale G, Ferrari C. PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCV-specific CD8 exhaustion. J Virol 2006, 80:11398-11403. 10.1128/JVI.01177-06, 1642188, 16956940.
-
(2006)
J Virol
, vol.80
, pp. 11398-11403
-
-
Urbani, S.1
Amadei, B.2
Tola, D.3
Massari, M.4
Schivazappa, S.5
Missale, G.6
Ferrari, C.7
-
25
-
-
77951258833
-
Features of responding T cells in cancer and chronic infection
-
10.1016/j.coi.2010.02.005, 2892208, 20207527
-
Kim PS, Ahmed R. Features of responding T cells in cancer and chronic infection. Curr Opin Immunol 2010, 22:223-230. 10.1016/j.coi.2010.02.005, 2892208, 20207527.
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 223-230
-
-
Kim, P.S.1
Ahmed, R.2
-
26
-
-
77949357362
-
T-cell exhaustion: characteristics, causes and conversion
-
10.1111/j.1365-2567.2010.03255.x, 2842494, 20201977
-
Yi JS, Cox MA, Zajac AJ. T-cell exhaustion: characteristics, causes and conversion. Immunology 2010, 129:474-481. 10.1111/j.1365-2567.2010.03255.x, 2842494, 20201977.
-
(2010)
Immunology
, vol.129
, pp. 474-481
-
-
Yi, J.S.1
Cox, M.A.2
Zajac, A.J.3
-
27
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
10.1038/nature05115, 16921384
-
Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, Mackey EW, Miller JD, Leslie AJ, DePierres C, Mncube Z, Duraiswamy J, Zhu B, Eichbaum Q, Altfeld M, Wherry EJ, Coovadia HM, Goulder PJ, Klenerman P, Ahmed R, Freeman GJ, Walker BD. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 2006, 443:350-354. 10.1038/nature05115, 16921384.
-
(2006)
Nature
, vol.443
, pp. 350-354
-
-
Day, C.L.1
Kaufmann, D.E.2
Kiepiela, P.3
Brown, J.A.4
Moodley, E.S.5
Reddy, S.6
Mackey, E.W.7
Miller, J.D.8
Leslie, A.J.9
DePierres, C.10
Mncube, Z.11
Duraiswamy, J.12
Zhu, B.13
Eichbaum, Q.14
Altfeld, M.15
Wherry, E.J.16
Coovadia, H.M.17
Goulder, P.J.18
Klenerman, P.19
Ahmed, R.20
Freeman, G.J.21
Walker, B.D.22
more..
-
28
-
-
33749324118
-
Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade
-
10.1084/jem.20061800, 2118103, 17000870
-
Freeman GJ, Wherry EJ, Ahmed R, Sharpe AH. Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade. J Exp Med 2006, 203:2223-2227. 10.1084/jem.20061800, 2118103, 17000870.
-
(2006)
J Exp Med
, vol.203
, pp. 2223-2227
-
-
Freeman, G.J.1
Wherry, E.J.2
Ahmed, R.3
Sharpe, A.H.4
-
29
-
-
70349562580
-
Programmed death 1 signaling on chronic myeloid leukemia-specific T cells results in T-cell exhaustion and disease progression
-
10.1182/blood-2008-09-179697, 19420358
-
Mumprecht S, Schurch C, Schwaller J, Solenthaler M, Ochsenbein AF. Programmed death 1 signaling on chronic myeloid leukemia-specific T cells results in T-cell exhaustion and disease progression. Blood 2009, 114:1528-1536. 10.1182/blood-2008-09-179697, 19420358.
-
(2009)
Blood
, vol.114
, pp. 1528-1536
-
-
Mumprecht, S.1
Schurch, C.2
Schwaller, J.3
Solenthaler, M.4
Ochsenbein, A.F.5
-
30
-
-
77953575514
-
PD-1/PD-L1 pathway and T-cell exhaustion in chronic hepatitis virus infection
-
Watanabe T, Bertoletti A, Tanoto TA. PD-1/PD-L1 pathway and T-cell exhaustion in chronic hepatitis virus infection. J Viral Hepat 2010, 17:453-458.
-
(2010)
J Viral Hepat
, vol.17
, pp. 453-458
-
-
Watanabe, T.1
Bertoletti, A.2
Tanoto, T.A.3
-
31
-
-
0037389094
-
2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference
-
10.1097/01.CCM.0000050454.01978.3B, 12682500
-
Levy MM, Fink MP, Marshall JC, Abraham E, Angus D, Cook D, Cohen J, Opal SM, Vincent JL, Ramsay G. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003, 31:1250-1256. 10.1097/01.CCM.0000050454.01978.3B, 12682500.
-
(2003)
Crit Care Med
, vol.31
, pp. 1250-1256
-
-
Levy, M.M.1
Fink, M.P.2
Marshall, J.C.3
Abraham, E.4
Angus, D.5
Cook, D.6
Cohen, J.7
Opal, S.M.8
Vincent, J.L.9
Ramsay, G.10
-
32
-
-
84856381402
-
A combined score of pro- and anti-inflammatory interleukins improves mortality prediction in severe sepsis
-
10.1016/j.cyto.2011.12.002, 22197776
-
Andaluz-Ojeda D, Bobillo F, Iglesias V, Almansa R, Rico L, Gandia F, Resino S, Tamayo E, de Lejarazu RO, Bermejo-Martin JF. A combined score of pro- and anti-inflammatory interleukins improves mortality prediction in severe sepsis. Cytokine 2012, 57:332-336. 10.1016/j.cyto.2011.12.002, 22197776.
-
(2012)
Cytokine
, vol.57
, pp. 332-336
-
-
Andaluz-Ojeda, D.1
Bobillo, F.2
Iglesias, V.3
Almansa, R.4
Rico, L.5
Gandia, F.6
Resino, S.7
Tamayo, E.8
de Lejarazu, R.O.9
Bermejo-Martin, J.F.10
-
33
-
-
60849114014
-
Compensatory anti-inflammatory response syndrome
-
Adib-Conquy M, Cavaillon JM. Compensatory anti-inflammatory response syndrome. Thromb Haemost 2009, 101:36-47.
-
(2009)
Thromb Haemost
, vol.101
, pp. 36-47
-
-
Adib-Conquy, M.1
Cavaillon, J.M.2
-
34
-
-
52149119860
-
Bim siRNA decreases lymphocyte apoptosis and improves survival in sepsis
-
Schwulst SJ, Muenzer JT, Peck-Palmer OM, Chang KC, Davis CG, McDonough JS, Osborne DF, Walton AH, Unsinger J, McDunn JE, Hotchkiss RS. Bim siRNA decreases lymphocyte apoptosis and improves survival in sepsis. Shock 2008, 30:127-134.
-
(2008)
Shock
, vol.30
, pp. 127-134
-
-
Schwulst, S.J.1
Muenzer, J.T.2
Peck-Palmer, O.M.3
Chang, K.C.4
Davis, C.G.5
McDonough, J.S.6
Osborne, D.F.7
Walton, A.H.8
Unsinger, J.9
McDunn, J.E.10
Hotchkiss, R.S.11
-
35
-
-
55349102040
-
Induction of Bim and Bid gene expression during accelerated apoptosis in severe sepsis
-
10.1186/cc7088, 2592767, 18925930
-
Weber SU, Schewe JC, Lehmann LE, Muller S, Book M, Klaschik S, Hoeft A, Stuber F. Induction of Bim and Bid gene expression during accelerated apoptosis in severe sepsis. Crit Care 2008, 12:R128. 10.1186/cc7088, 2592767, 18925930.
-
(2008)
Crit Care
, vol.12
-
-
Weber, S.U.1
Schewe, J.C.2
Lehmann, L.E.3
Muller, S.4
Book, M.5
Klaschik, S.6
Hoeft, A.7
Stuber, F.8
-
36
-
-
29144514677
-
Both percentage of gammadelta T lymphocytes and CD3 expression are reduced during septic shock
-
10.1097/01.CCM.0000189745.66585.AE, 16352967
-
Venet F, Bohe J, Debard AL, Bienvenu J, Lepape A, Monneret G. Both percentage of gammadelta T lymphocytes and CD3 expression are reduced during septic shock. Crit Care Med 2005, 33:2836-2840. 10.1097/01.CCM.0000189745.66585.AE, 16352967.
-
(2005)
Crit Care Med
, vol.33
, pp. 2836-2840
-
-
Venet, F.1
Bohe, J.2
Debard, A.L.3
Bienvenu, J.4
Lepape, A.5
Monneret, G.6
-
37
-
-
77957690699
-
Early assessment of leukocyte alterations at diagnosis of septic shock
-
10.1097/SHK.0b013e3181dc0977, 20220566
-
Venet F, Davin F, Guignant C, Larue A, Cazalis MA, Darbon R, Allombert C, Mougin B, Malcus C, Poitevin-Later F, Lepape A, Monneret G. Early assessment of leukocyte alterations at diagnosis of septic shock. Shock 2010, 34:358-363. 10.1097/SHK.0b013e3181dc0977, 20220566.
-
(2010)
Shock
, vol.34
, pp. 358-363
-
-
Venet, F.1
Davin, F.2
Guignant, C.3
Larue, A.4
Cazalis, M.A.5
Darbon, R.6
Allombert, C.7
Mougin, B.8
Malcus, C.9
Poitevin-Later, F.10
Lepape, A.11
Monneret, G.12
-
38
-
-
48249107889
-
Apoptosis in sepsis: mechanisms, clinical impact and potential therapeutic targets
-
10.2174/138161208784980617, 18691096
-
Ayala A, Perl M, Venet F, Lomas-Neira J, Swan R, Chung CS. Apoptosis in sepsis: mechanisms, clinical impact and potential therapeutic targets. Curr Pharm Des 2008, 14:1853-1859. 10.2174/138161208784980617, 18691096.
-
(2008)
Curr Pharm Des
, vol.14
, pp. 1853-1859
-
-
Ayala, A.1
Perl, M.2
Venet, F.3
Lomas-Neira, J.4
Swan, R.5
Chung, C.S.6
-
39
-
-
77955009943
-
Deficiency of Bid protein reduces sepsis-induced apoptosis and inflammation, while improving septic survival
-
10.1097/SHK.0b013e3181cf70fb, 2909339, 20023601
-
Chung CS, Venet F, Chen Y, Jones LN, Wilson DC, Ayala CA, Ayala A. Deficiency of Bid protein reduces sepsis-induced apoptosis and inflammation, while improving septic survival. Shock 2010, 34:150-161. 10.1097/SHK.0b013e3181cf70fb, 2909339, 20023601.
-
(2010)
Shock
, vol.34
, pp. 150-161
-
-
Chung, C.S.1
Venet, F.2
Chen, Y.3
Jones, L.N.4
Wilson, D.C.5
Ayala, C.A.6
Ayala, A.7
-
40
-
-
78349287748
-
Lack of recovery in monocyte human leukocyte antigen-DR expression is independently associated with the development of sepsis after major trauma
-
10.1186/cc9331, 3220028, 21092108
-
Cheron A, Floccard B, Allaouchiche B, Guignant C, Poitevin F, Malcus C, Crozon J, Faure A, Guillaume C, Marcotte G, Vulliez A, Monneuse O, Monneret G. Lack of recovery in monocyte human leukocyte antigen-DR expression is independently associated with the development of sepsis after major trauma. Crit Care 2010, 14:R208. 10.1186/cc9331, 3220028, 21092108.
-
(2010)
Crit Care
, vol.14
-
-
Cheron, A.1
Floccard, B.2
Allaouchiche, B.3
Guignant, C.4
Poitevin, F.5
Malcus, C.6
Crozon, J.7
Faure, A.8
Guillaume, C.9
Marcotte, G.10
Vulliez, A.11
Monneuse, O.12
Monneret, G.13
-
41
-
-
78650419440
-
Low monocyte human leukocyte antigen-DR is independently associated with nosocomial infections after septic shock
-
10.1007/s00134-010-1962-x, 20652682
-
Landelle C, Lepape A, Voirin N, Tognet E, BoFhé J, Vanhems P, Monneret G. Low monocyte human leukocyte antigen-DR is independently associated with nosocomial infections after septic shock. Intensive Care Med 2010, 36:1859-1866. 10.1007/s00134-010-1962-x, 20652682.
-
(2010)
Intensive Care Med
, vol.36
, pp. 1859-1866
-
-
Landelle, C.1
Lepape, A.2
Voirin, N.3
Tognet, E.4
BoFhé, J.5
Vanhems, P.6
Monneret, G.7
-
42
-
-
80054114483
-
Clinical review: flow cytometry perspectives in the ICU - from diagnosis of infection to monitoring of injury-induced immune dysfunctions
-
10.1186/cc10333, 22017882
-
Venet F, Lepape A, Monneret G. Clinical review: flow cytometry perspectives in the ICU - from diagnosis of infection to monitoring of injury-induced immune dysfunctions. Crit Care 2011, 15:231. 10.1186/cc10333, 22017882.
-
(2011)
Crit Care
, vol.15
, pp. 231
-
-
Venet, F.1
Lepape, A.2
Monneret, G.3
-
43
-
-
33947407689
-
Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression
-
10.1128/JVI.02021-06, 1865979, 17182670
-
Radziewicz H, Ibegbu CC, Fernandez ML, Workowski KA, Obideen K, Wehbi M, Hanson HL, Steinberg JP, Masopust D, Eherry EJ, Altman JD, Rouse BT, Freeman GJ, Ahmed R, Grakoui A. Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression. J Virol 2007, 81:2545-2553. 10.1128/JVI.02021-06, 1865979, 17182670.
-
(2007)
J Virol
, vol.81
, pp. 2545-2553
-
-
Radziewicz, H.1
Ibegbu, C.C.2
Fernandez, M.L.3
Workowski, K.A.4
Obideen, K.5
Wehbi, M.6
Hanson, H.L.7
Steinberg, J.P.8
Masopust, D.9
Eherry, E.J.10
Altman, J.D.11
Rouse, B.T.12
Freeman, G.J.13
Ahmed, R.14
Grakoui, A.15
-
44
-
-
41649118631
-
T-cell exhaustion in HIV infection
-
10.1007/s11904-008-0003-7, 18417030
-
El-Far M, Halwani R, Said E, Trautmann L, Doroudchi M, Janbazian L, Fonseca S, van Grevenynghe J, Yassine-Diab B, Sekaly RP, Haddad EK. T-cell exhaustion in HIV infection. Curr HIV/AIDS Rep 2008, 5:13-19. 10.1007/s11904-008-0003-7, 18417030.
-
(2008)
Curr HIV/AIDS Rep
, vol.5
, pp. 13-19
-
-
El-Far, M.1
Halwani, R.2
Said, E.3
Trautmann, L.4
Doroudchi, M.5
Janbazian, L.6
Fonseca, S.7
van Grevenynghe, J.8
Yassine-Diab, B.9
Sekaly, R.P.10
Haddad, E.K.11
-
45
-
-
75149117314
-
Antiviral intrahepatic T-cell responses can be restored by blocking programmed death-1 pathway in chronic hepatitis B
-
10.1053/j.gastro.2009.09.052, 19800335
-
Fisicaro P, Valdatta C, Massari M, Loggi E, Biasini E, Sacchelli L, Cavallo MC, Silini EM, Andreone P, Missale G, Ferrari C. Antiviral intrahepatic T-cell responses can be restored by blocking programmed death-1 pathway in chronic hepatitis B. Gastroenterology 2010, 138:682-693. 10.1053/j.gastro.2009.09.052, 19800335.
-
(2010)
Gastroenterology
, vol.138
, pp. 682-693
-
-
Fisicaro, P.1
Valdatta, C.2
Massari, M.3
Loggi, E.4
Biasini, E.5
Sacchelli, L.6
Cavallo, M.C.7
Silini, E.M.8
Andreone, P.9
Missale, G.10
Ferrari, C.11
-
46
-
-
77951881216
-
Dendritic cell inhibition is connected to exhaustion of CD8+ T cell polyfunctionality during chronic hepatitis C virus infection
-
10.4049/jimmunol.0902522, 20173023
-
Rodrigue-Gervais IG, Rigsby H, Jouan L, Sauve D, Sekaly RP, Willems B, Lamarre D. Dendritic cell inhibition is connected to exhaustion of CD8+ T cell polyfunctionality during chronic hepatitis C virus infection. J Immunol 2010, 184:3134-3144. 10.4049/jimmunol.0902522, 20173023.
-
(2010)
J Immunol
, vol.184
, pp. 3134-3144
-
-
Rodrigue-Gervais, I.G.1
Rigsby, H.2
Jouan, L.3
Sauve, D.4
Sekaly, R.P.5
Willems, B.6
Lamarre, D.7
-
47
-
-
79952705605
-
Revisiting immune exhaustion during HIV infection
-
10.1007/s11904-010-0066-0, 3144861, 21188556
-
Khaitan A, Unutmaz D. Revisiting immune exhaustion during HIV infection. Curr HIV/AIDS Rep 2011, 8:4-11. 10.1007/s11904-010-0066-0, 3144861, 21188556.
-
(2011)
Curr HIV/AIDS Rep
, vol.8
, pp. 4-11
-
-
Khaitan, A.1
Unutmaz, D.2
-
48
-
-
38849135780
-
CD40 and CD80/86 act synergistically to regulate inflammation and mortality in polymicrobial sepsis
-
2218847, 17989345
-
Nolan A, Weiden M, Kelly A, Hoshino Y, Hoshino S, Mehta N, Gold JA. CD40 and CD80/86 act synergistically to regulate inflammation and mortality in polymicrobial sepsis. Am J Respir Crit Care Med 2008, 177:301-308. 2218847, 17989345.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 301-308
-
-
Nolan, A.1
Weiden, M.2
Kelly, A.3
Hoshino, Y.4
Hoshino, S.5
Mehta, N.6
Gold, J.A.7
-
49
-
-
77749285677
-
How chronic viral infections impact on antigen-specific T-cell responses
-
10.1002/eji.200940102, 20077405
-
Frebel H, Richter K, Oxenius A. How chronic viral infections impact on antigen-specific T-cell responses. Eur J Immunol 2010, 40:654-663. 10.1002/eji.200940102, 20077405.
-
(2010)
Eur J Immunol
, vol.40
, pp. 654-663
-
-
Frebel, H.1
Richter, K.2
Oxenius, A.3
-
50
-
-
79956077563
-
T cell exhaustion
-
Wherry EJ. T cell exhaustion. Nat Immunol 2011, 12:492-499.
-
(2011)
Nat Immunol
, vol.12
, pp. 492-499
-
-
Wherry, E.J.1
-
51
-
-
77956403940
-
Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis
-
10.1189/jlb.0110037, 20483923
-
Brahmamdam P, Inoue S, Unsinger J, Chang KC, McDunn JE, Hotchkiss RS. Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis. J Leukoc Biol 2010, 88:233-240. 10.1189/jlb.0110037, 20483923.
-
(2010)
J Leukoc Biol
, vol.88
, pp. 233-240
-
-
Brahmamdam, P.1
Inoue, S.2
Unsinger, J.3
Chang, K.C.4
McDunn, J.E.5
Hotchkiss, R.S.6
-
52
-
-
79953121419
-
Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients
-
10.1186/cc10112, 3219369, 21418617
-
Guignant C, Lepape A, Huang X, Kherouf H, Denis L, Poitevin F, Malcus C, Cheron A, Allaouchiche B, Gueyffier F, Ayala A, Monneret G, Venet F. Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients. Crit Care 2011, 15:R99. 10.1186/cc10112, 3219369, 21418617.
-
(2011)
Crit Care
, vol.15
-
-
Guignant, C.1
Lepape, A.2
Huang, X.3
Kherouf, H.4
Denis, L.5
Poitevin, F.6
Malcus, C.7
Cheron, A.8
Allaouchiche, B.9
Gueyffier, F.10
Ayala, A.11
Monneret, G.12
Venet, F.13
-
53
-
-
79951947339
-
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients
-
10.1186/cc10059, 3222003, 21349174
-
Zhang Y, Li J, Lou J, Zhou Y, Bo L, Zhu J, Zhu K, Wan X, Cai Z, Deng X. Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients. Crit Care 2011, 15:R70. 10.1186/cc10059, 3222003, 21349174.
-
(2011)
Crit Care
, vol.15
-
-
Zhang, Y.1
Li, J.2
Lou, J.3
Zhou, Y.4
Bo, L.5
Zhu, J.6
Zhu, K.7
Wan, X.8
Cai, Z.9
Deng, X.10
-
54
-
-
78649460067
-
PD-L1 blockade improves survival in experimental sepsis by inhibiting lymphocyte apoptosis and reversing monocyte dysfunction
-
10.1186/cc9354, 3220038, 21118528
-
Zhang Y, Zhou Y, Lou J, Li J, Bo L, Zhu K, Wan X, Deng X, Cai Z. PD-L1 blockade improves survival in experimental sepsis by inhibiting lymphocyte apoptosis and reversing monocyte dysfunction. Crit Care 2010, 14:R220. 10.1186/cc9354, 3220038, 21118528.
-
(2010)
Crit Care
, vol.14
-
-
Zhang, Y.1
Zhou, Y.2
Lou, J.3
Li, J.4
Bo, L.5
Zhu, K.6
Wan, X.7
Deng, X.8
Cai, Z.9
-
55
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
10.1084/jem.192.7.1027, 2193311, 11015443
-
Freeman GJ, Long AJ, Iwai Y, Bourque K, Chernova T, Nishimura H, Fitz LJ, Malenkovich N, Okazaki T, Byrne MC, Horton HF, Fouser L, Carter L, Ling V, Bowman MR, Carreno BM, Collins M, Wood CR, Honjo T. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med 2000, 192:1027-1034. 10.1084/jem.192.7.1027, 2193311, 11015443.
-
(2000)
J Exp Med
, vol.192
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
Nishimura, H.6
Fitz, L.J.7
Malenkovich, N.8
Okazaki, T.9
Byrne, M.C.10
Horton, H.F.11
Fouser, L.12
Carter, L.13
Ling, V.14
Bowman, M.R.15
Carreno, B.M.16
Collins, M.17
Wood, C.R.18
Honjo, T.19
-
56
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
10.1038/nature04444, 16382236
-
Barber DL, Wherry EJ, Masopust D, Zhu B, Allison JP, Sharpe AH, Freeman GJ, Ahmed R. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 2006, 439:682-687. 10.1038/nature04444, 16382236.
-
(2006)
Nature
, vol.439
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
57
-
-
35349014587
-
Molecular signature of CD8+ T cell exhaustion during chronic viral infection
-
10.1016/j.immuni.2007.09.006, 17950003
-
Wherry EJ, Ha SJ, Kaech SM, Haining WN, Sarkar S, Kalia V, S Subramaniam S, Blattman JN, Barber DL, Ahmed R. Molecular signature of CD8+ T cell exhaustion during chronic viral infection. Immunity 2007, 27:670-684. 10.1016/j.immuni.2007.09.006, 17950003.
-
(2007)
Immunity
, vol.27
, pp. 670-684
-
-
Wherry, E.J.1
Ha, S.J.2
Kaech, S.M.3
Haining, W.N.4
Sarkar, S.5
Kalia, V.6
S Subramaniam, S.7
Blattman, J.N.8
Barber, D.L.9
Ahmed, R.10
-
58
-
-
33751576739
-
Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis
-
Scumpia PO, Delano MJ, Kelly KM, O'Malley KA, Efron PA, McAuliffe PF, Brusko T, Ungaro R, Barker T, Wynn JL, Atkinson MA, Reeves WH, Salzler MJ, Moldawer LL. Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis. J Immunol 2006, 177:7943-7949.
-
(2006)
J Immunol
, vol.177
, pp. 7943-7949
-
-
Scumpia, P.O.1
Delano, M.J.2
Kelly, K.M.3
O'Malley, K.A.4
Efron, P.A.5
McAuliffe, P.F.6
Brusko, T.7
Ungaro, R.8
Barker, T.9
Wynn, J.L.10
Atkinson, M.A.11
Reeves, W.H.12
Salzler, M.J.13
Moldawer, L.L.14
-
59
-
-
33750306678
-
Human CD4+CD25+ regulatory T lymphocytes inhibit lipopolysaccharide-induced monocyte survival through a Fas/Fas ligand-dependent mechanism
-
Venet F, Pachot A, Debard A-L, Bohe J, Bienvenu J, Lepape A, Powell WS, Monneret G. Human CD4+CD25+ regulatory T lymphocytes inhibit lipopolysaccharide-induced monocyte survival through a Fas/Fas ligand-dependent mechanism. J Immunol 2006, 177:6540-6547.
-
(2006)
J Immunol
, vol.177
, pp. 6540-6547
-
-
Venet, F.1
Pachot, A.2
Debard, A.-L.3
Bohe, J.4
Bienvenu, J.5
Lepape, A.6
Powell, W.S.7
Monneret, G.8
-
60
-
-
77953939271
-
The post sepsis-induced expansion and enhanced function of regulatory T cells create an environment to potentiate tumor growth
-
10.1182/blood-2009-09-241083, 2881495, 20130237
-
Cavassani KA, Carson WF, Moreira AP, Wen H, Schaller MA, Ishii M, Lindell DM, Dou Y, Lukacs NW, Keshamouni VG, Hogaboam CM, Kunkel SL. The post sepsis-induced expansion and enhanced function of regulatory T cells create an environment to potentiate tumor growth. Blood 2010, 115:4403-4411. 10.1182/blood-2009-09-241083, 2881495, 20130237.
-
(2010)
Blood
, vol.115
, pp. 4403-4411
-
-
Cavassani, K.A.1
Carson, W.F.2
Moreira, A.P.3
Wen, H.4
Schaller, M.A.5
Ishii, M.6
Lindell, D.M.7
Dou, Y.8
Lukacs, N.W.9
Keshamouni, V.G.10
Hogaboam, C.M.11
Kunkel, S.L.12
-
61
-
-
77953264865
-
Percentages of CD4+ T regulatory cells and HLA-DR expressing monocytes in severe intra-abdominal infections
-
10.3109/00365541003660021, 20233010
-
Fu Q, Cui N, Yu W, Du C. Percentages of CD4+ T regulatory cells and HLA-DR expressing monocytes in severe intra-abdominal infections. Scand J Infect Dis 2010, 42:475-478. 10.3109/00365541003660021, 20233010.
-
(2010)
Scand J Infect Dis
, vol.42
, pp. 475-478
-
-
Fu, Q.1
Cui, N.2
Yu, W.3
Du, C.4
-
62
-
-
8544236263
-
Increased percentage of CD4+CD25+ regulatory T cells during septic shock is due to the decrease of CD4+CD25- lymphocytes
-
Venet F, Pachot A, Debard AL, Bohe J, Bienvenu J, Lepape A, Monneret G. Increased percentage of CD4+CD25+ regulatory T cells during septic shock is due to the decrease of CD4+CD25- lymphocytes. Crit Care Med 2004, 32:2329-2331.
-
(2004)
Crit Care Med
, vol.32
, pp. 2329-2331
-
-
Venet, F.1
Pachot, A.2
Debard, A.L.3
Bohe, J.4
Bienvenu, J.5
Lepape, A.6
Monneret, G.7
|