-
1
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Alexandrov, L.B., Nik-Zainal, S., Wedge, D.C., Aparicio, S.A., Behjati, S., Biankin, A.V., Bignell, G.R., Bolli, N., Borg, A., Borresen-Dale, A.L., et al. Signatures of mutational processes in human cancer. Nature 500 (2013), 415–421.
-
(2013)
Nature
, vol.500
, pp. 415-421
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
Aparicio, S.A.4
Behjati, S.5
Biankin, A.V.6
Bignell, G.R.7
Bolli, N.8
Borg, A.9
Borresen-Dale, A.L.10
-
2
-
-
84949207578
-
Systematic pan-cancer analysis of tumour purity
-
Aran, D., Sirota, M., Butte, A.J., Systematic pan-cancer analysis of tumour purity. Nat. Commun., 6, 2015, 8971.
-
(2015)
Nat. Commun.
, vol.6
, pp. 8971
-
-
Aran, D.1
Sirota, M.2
Butte, A.J.3
-
3
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
Bao, S., Wu, Q., McLendon, R.E., Hao, Y., Shi, Q., Hjelmeland, A.B., Dewhirst, M.W., Bigner, D.D., Rich, J.N., Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 444 (2006), 756–760.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
4
-
-
70449091786
-
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
-
Barbie, D.A., Tamayo, P., Boehm, J.S., Kim, S.Y., Moody, S.E., Dunn, I.F., Schinzel, A.C., Sandy, P., Meylan, E., Scholl, C., et al. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature 462 (2009), 108–112.
-
(2009)
Nature
, vol.462
, pp. 108-112
-
-
Barbie, D.A.1
Tamayo, P.2
Boehm, J.S.3
Kim, S.Y.4
Moody, S.E.5
Dunn, I.F.6
Schinzel, A.C.7
Sandy, P.8
Meylan, E.9
Scholl, C.10
-
5
-
-
84876435048
-
G-cimp status prediction of glioblastoma samples using mRNA expression data
-
Baysan, M., Bozdag, S., Cam, M.C., Kotliarova, S., Ahn, S., Walling, J., Killian, J.K., Stevenson, H., Meltzer, P., Fine, H.A., G-cimp status prediction of glioblastoma samples using mRNA expression data. PLoS One, 7, 2012, e47839.
-
(2012)
PLoS One
, vol.7
, pp. e47839
-
-
Baysan, M.1
Bozdag, S.2
Cam, M.C.3
Kotliarova, S.4
Ahn, S.5
Walling, J.6
Killian, J.K.7
Stevenson, H.8
Meltzer, P.9
Fine, H.A.10
-
6
-
-
63549083845
-
A single-sample method for normalizing and combining full-resolution copy numbers from multiple platforms, labs and analysis methods
-
Bengtsson, H., Ray, A., Spellman, P., Speed, T.P., A single-sample method for normalizing and combining full-resolution copy numbers from multiple platforms, labs and analysis methods. Bioinformatics 25 (2009), 861–867.
-
(2009)
Bioinformatics
, vol.25
, pp. 861-867
-
-
Bengtsson, H.1
Ray, A.2
Spellman, P.3
Speed, T.P.4
-
7
-
-
84883656941
-
Mesenchymal differentiation mediated by NF-kappaB promotes radiation resistance in glioblastoma
-
Bhat, K.P., Balasubramaniyan, V., Vaillant, B., Ezhilarasan, R., Hummelink, K., Hollingsworth, F., Wani, K., Heathcock, L., James, J.D., Goodman, L.D., et al. Mesenchymal differentiation mediated by NF-kappaB promotes radiation resistance in glioblastoma. Cancer Cell 24 (2013), 331–346.
-
(2013)
Cancer Cell
, vol.24
, pp. 331-346
-
-
Bhat, K.P.1
Balasubramaniyan, V.2
Vaillant, B.3
Ezhilarasan, R.4
Hummelink, K.5
Hollingsworth, F.6
Wani, K.7
Heathcock, L.8
James, J.D.9
Goodman, L.D.10
-
8
-
-
84966309581
-
Cancer immunology. The “cancer immunogram”
-
Blank, C.U., Haanen, J.B., Ribas, A., Schumacher, T.N., Cancer immunology. The “cancer immunogram”. Science 352 (2016), 658–660.
-
(2016)
Science
, vol.352
, pp. 658-660
-
-
Blank, C.U.1
Haanen, J.B.2
Ribas, A.3
Schumacher, T.N.4
-
9
-
-
84976467739
-
Immune checkpoint inhibition for hypermutant glioblastoma multiforme resulting from germline biallelic mismatch repair deficiency
-
Bouffet, E., Larouche, V., Campbell, B.B., Merico, D., de Borja, R., Aronson, M., Durno, C., Krueger, J., Cabric, V., Ramaswamy, V., et al. Immune checkpoint inhibition for hypermutant glioblastoma multiforme resulting from germline biallelic mismatch repair deficiency. J. Clin. Oncol. 34 (2016), 2206–2211.
-
(2016)
J. Clin. Oncol.
, vol.34
, pp. 2206-2211
-
-
Bouffet, E.1
Larouche, V.2
Campbell, B.B.3
Merico, D.4
de Borja, R.5
Aronson, M.6
Durno, C.7
Krueger, J.8
Cabric, V.9
Ramaswamy, V.10
-
10
-
-
85014007176
-
GlioVis data portal for visualization and analysis of brain tumor expression datasets
-
Bowman, R.L., Wang, Q., Carro, A., Verhaak, R.G., Squatrito, M., GlioVis data portal for visualization and analysis of brain tumor expression datasets. Neuro Oncol. 19 (2017), 139–141.
-
(2017)
Neuro Oncol.
, vol.19
, pp. 139-141
-
-
Bowman, R.L.1
Wang, Q.2
Carro, A.3
Verhaak, R.G.4
Squatrito, M.5
-
11
-
-
84885074034
-
The somatic genomic landscape of glioblastoma
-
Brennan, C.W., Verhaak, R.G., McKenna, A., Campos, B., Noushmehr, H., Salama, S.R., Zheng, S., Chakravarty, D., Sanborn, J.Z., Berman, S.H., et al. The somatic genomic landscape of glioblastoma. Cell 155 (2013), 462–477.
-
(2013)
Cell
, vol.155
, pp. 462-477
-
-
Brennan, C.W.1
Verhaak, R.G.2
McKenna, A.3
Campos, B.4
Noushmehr, H.5
Salama, S.R.6
Zheng, S.7
Chakravarty, D.8
Sanborn, J.Z.9
Berman, S.H.10
-
12
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research, Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455 (2008), 1061–1068.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
13
-
-
84932628860
-
Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas
-
Cancer Genome Atlas Research Network, Brat, D.J., Verhaak, R.G., Aldape, K.D., Yung, W.K., Salama, S.R., Cooper, L.A., Rheinbay, E., Miller, C.R., Vitucci, M., Morozova, O., et al. Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas. N. Engl. J. Med. 372 (2015), 2481–2498.
-
(2015)
N. Engl. J. Med.
, vol.372
, pp. 2481-2498
-
-
Brat, D.J.1
Verhaak, R.G.2
Aldape, K.D.3
Yung, W.K.4
Salama, S.R.5
Cooper, L.A.6
Rheinbay, E.7
Miller, C.R.8
Vitucci, M.9
Morozova, O.10
-
14
-
-
84860782006
-
Absolute quantification of somatic DNA alterations in human cancer
-
Carter, S.L., Cibulskis, K., Helman, E., McKenna, A., Shen, H., Zack, T., Laird, P.W., Onofrio, R.C., Winckler, W., Weir, B.A., et al. Absolute quantification of somatic DNA alterations in human cancer. Nat. Biotechnol. 30 (2012), 413–421.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 413-421
-
-
Carter, S.L.1
Cibulskis, K.2
Helman, E.3
McKenna, A.4
Shen, H.5
Zack, T.6
Laird, P.W.7
Onofrio, R.C.8
Winckler, W.9
Weir, B.A.10
-
15
-
-
84955561447
-
Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma
-
Ceccarelli, M., Barthel, F.P., Malta, T.M., Sabedot, T.S., Salama, S.R., Murray, B.A., Morozova, O., Newton, Y., Radenbaugh, A., Pagnotta, S.M., et al. Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma. Cell 164 (2016), 550–563.
-
(2016)
Cell
, vol.164
, pp. 550-563
-
-
Ceccarelli, M.1
Barthel, F.P.2
Malta, T.M.3
Sabedot, T.S.4
Salama, S.R.5
Murray, B.A.6
Morozova, O.7
Newton, Y.8
Radenbaugh, A.9
Pagnotta, S.M.10
-
16
-
-
29144535372
-
Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data
-
Dai, M., Wang, P., Boyd, A.D., Kostov, G., Athey, B., Jones, E.G., Bunney, W.E., Myers, R.M., Speed, T.P., Akil, H., et al. Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Res., 33, 2005, e175.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. e175
-
-
Dai, M.1
Wang, P.2
Boyd, A.D.3
Kostov, G.4
Athey, B.5
Jones, E.G.6
Bunney, W.E.7
Myers, R.M.8
Speed, T.P.9
Akil, H.10
-
17
-
-
84893876109
-
Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice
-
Deng, L., Liang, H., Burnette, B., Beckett, M., Darga, T., Weichselbaum, R.R., Fu, Y.X., Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice. J. Clin. Invest. 124 (2014), 687–695.
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 687-695
-
-
Deng, L.1
Liang, H.2
Burnette, B.3
Beckett, M.4
Darga, T.5
Weichselbaum, R.R.6
Fu, Y.X.7
-
18
-
-
84897527381
-
Immune heterogeneity of glioblastoma subtypes: extrapolation from the Cancer Genome Atlas
-
Doucette, T., Rao, G., Rao, A., Shen, L., Aldape, K., Wei, J., Dziurzynski, K., Gilbert, M., Heimberger, A.B., Immune heterogeneity of glioblastoma subtypes: extrapolation from the Cancer Genome Atlas. Cancer Immunol. Res. 1 (2013), 112–122.
-
(2013)
Cancer Immunol. Res.
, vol.1
, pp. 112-122
-
-
Doucette, T.1
Rao, G.2
Rao, A.3
Shen, L.4
Aldape, K.5
Wei, J.6
Dziurzynski, K.7
Gilbert, M.8
Heimberger, A.B.9
-
19
-
-
84859847164
-
Emerging insights into the molecular and cellular basis of glioblastoma
-
Dunn, G.P., Rinne, M.L., Wykosky, J., Genovese, G., Quayle, S.N., Dunn, I.F., Agarwalla, P.K., Chheda, M.G., Campos, B., Wang, A., et al. Emerging insights into the molecular and cellular basis of glioblastoma. Genes Dev. 26 (2012), 756–784.
-
(2012)
Genes Dev.
, vol.26
, pp. 756-784
-
-
Dunn, G.P.1
Rinne, M.L.2
Wykosky, J.3
Genovese, G.4
Quayle, S.N.5
Dunn, I.F.6
Agarwalla, P.K.7
Chheda, M.G.8
Campos, B.9
Wang, A.10
-
20
-
-
84865199671
-
Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas
-
Engler, J.R., Robinson, A.E., Smirnov, I., Hodgson, J.G., Berger, M.S., Gupta, N., James, C.D., Molinaro, A., Phillips, J.J., Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas. PLoS One, 7, 2012, e43339.
-
(2012)
PLoS One
, vol.7
, pp. e43339
-
-
Engler, J.R.1
Robinson, A.E.2
Smirnov, I.3
Hodgson, J.G.4
Berger, M.S.5
Gupta, N.6
James, C.D.7
Molinaro, A.8
Phillips, J.J.9
-
21
-
-
84975276172
-
Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype
-
Gabrusiewicz, K., Rodriguez, B., Wei, J., Hashimoto, Y., Healy, L.M., Maiti, S.N., Thomas, G., Zhou, S., Wang, Q., Elakkad, A., et al. Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype. JCI Insight, 1, 2016, 10.1172/jci.insight.85841.
-
(2016)
JCI Insight
, vol.1
-
-
Gabrusiewicz, K.1
Rodriguez, B.2
Wei, J.3
Hashimoto, Y.4
Healy, L.M.5
Maiti, S.N.6
Thomas, G.7
Zhou, S.8
Wang, Q.9
Elakkad, A.10
-
22
-
-
84906673966
-
MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma
-
Gill, B.J., Pisapia, D.J., Malone, H.R., Goldstein, H., Lei, L., Sonabend, A., Yun, J., Samanamud, J., Sims, J.S., Banu, M., et al. MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma. Proc. Natl. Acad. Sci. USA 111 (2014), 12550–12555.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 12550-12555
-
-
Gill, B.J.1
Pisapia, D.J.2
Malone, H.R.3
Goldstein, H.4
Lei, L.5
Sonabend, A.6
Yun, J.7
Samanamud, J.8
Sims, J.S.9
Banu, M.10
-
23
-
-
84953747412
-
The role of microglia and macrophages in glioma maintenance and progression
-
Hambardzumyan, D., Gutmann, D.H., Kettenmann, H., The role of microglia and macrophages in glioma maintenance and progression. Nat. Neurosci. 19 (2015), 20–27.
-
(2015)
Nat. Neurosci.
, vol.19
, pp. 20-27
-
-
Hambardzumyan, D.1
Gutmann, D.H.2
Kettenmann, H.3
-
24
-
-
84995893096
-
Epigenetic activation of WNT5A drives glioblastoma stem cell differentiation and invasive growth
-
Hu, B., Wang, Q., Wang, Y.A., Hua, S., Sauve, C.G., Ong, D., Lan, Z.D., Chang, Q., Ho, Y.W., Monasterio, M.M., et al. Epigenetic activation of WNT5A drives glioblastoma stem cell differentiation and invasive growth. Cell 167 (2016), 1281–1295.e18.
-
(2016)
Cell
, vol.167
, pp. 1281-1295.e18
-
-
Hu, B.1
Wang, Q.2
Wang, Y.A.3
Hua, S.4
Sauve, C.G.5
Ong, D.6
Lan, Z.D.7
Chang, Q.8
Ho, Y.W.9
Monasterio, M.M.10
-
25
-
-
33646256145
-
A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy
-
Hunter, C., Smith, R., Cahill, D.P., Stephens, P., Stevens, C., Teague, J., Greenman, C., Edkins, S., Bignell, G., Davies, H., et al. A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy. Cancer Res. 66 (2006), 3987–3991.
-
(2006)
Cancer Res.
, vol.66
, pp. 3987-3991
-
-
Hunter, C.1
Smith, R.2
Cahill, D.P.3
Stephens, P.4
Stevens, C.5
Teague, J.6
Greenman, C.7
Edkins, S.8
Bignell, G.9
Davies, H.10
-
26
-
-
79957905986
-
Molecular subclassification of diffuse gliomas: seeing order in the chaos
-
Huse, J.T., Phillips, H.S., Brennan, C.W., Molecular subclassification of diffuse gliomas: seeing order in the chaos. Glia 59 (2011), 1190–1199.
-
(2011)
Glia
, vol.59
, pp. 1190-1199
-
-
Huse, J.T.1
Phillips, H.S.2
Brennan, C.W.3
-
27
-
-
84925701525
-
Stromal contribution to the colorectal cancer transcriptome
-
Isella, C., Terrasi, A., Bellomo, S.E., Petti, C., Galatola, G., Muratore, A., Mellano, A., Senetta, R., Cassenti, A., Sonetto, C., et al. Stromal contribution to the colorectal cancer transcriptome. Nat. Genet. 47 (2015), 312–319.
-
(2015)
Nat. Genet.
, vol.47
, pp. 312-319
-
-
Isella, C.1
Terrasi, A.2
Bellomo, S.E.3
Petti, C.4
Galatola, G.5
Muratore, A.6
Mellano, A.7
Senetta, R.8
Cassenti, A.9
Sonetto, C.10
-
28
-
-
84995511734
-
Immunogenomics of hypermutated glioblastoma: a patient with germline POLE deficiency treated with checkpoint blockade immunotherapy
-
Johanns, T.M., Miller, C.A., Dorward, I.G., Tsien, C., Chang, E., Perry, A., Uppaluri, R., Ferguson, C., Schmidt, R.E., Dahiya, S., et al. Immunogenomics of hypermutated glioblastoma: a patient with germline POLE deficiency treated with checkpoint blockade immunotherapy. Cancer Discov. 6 (2016), 1230–1236.
-
(2016)
Cancer Discov.
, vol.6
, pp. 1230-1236
-
-
Johanns, T.M.1
Miller, C.A.2
Dorward, I.G.3
Tsien, C.4
Chang, E.5
Perry, A.6
Uppaluri, R.7
Ferguson, C.8
Schmidt, R.E.9
Dahiya, S.10
-
29
-
-
84873110988
-
Patient-specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ
-
Joo, K.M., Kim, J., Jin, J., Kim, M., Seol, H.J., Muradov, J., Yang, H., Choi, Y.L., Park, W.Y., Kong, D.S., et al. Patient-specific orthotopic glioblastoma xenograft models recapitulate the histopathology and biology of human glioblastomas in situ. Cell Rep. 3 (2013), 260–273.
-
(2013)
Cell Rep.
, vol.3
, pp. 260-273
-
-
Joo, K.M.1
Kim, J.2
Jin, J.3
Kim, M.4
Seol, H.J.5
Muradov, J.6
Yang, H.7
Choi, Y.L.8
Park, W.Y.9
Kong, D.S.10
-
30
-
-
84925699872
-
Transcriptional mimicry by tumor-associated stroma
-
Kim, H., Verhaak, R.G., Transcriptional mimicry by tumor-associated stroma. Nat. Genet. 47 (2015), 307–309.
-
(2015)
Nat. Genet.
, vol.47
, pp. 307-309
-
-
Kim, H.1
Verhaak, R.G.2
-
31
-
-
84923911546
-
Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution
-
Kim, H., Zheng, S., Amini, S.S., Virk, S.M., Mikkelsen, T., Brat, D.J., Grimsby, J., Sougnez, C., Muller, F., Hu, J., et al. Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution. Genome Res. 25 (2015), 316–327.
-
(2015)
Genome Res.
, vol.25
, pp. 316-327
-
-
Kim, H.1
Zheng, S.2
Amini, S.S.3
Virk, S.M.4
Mikkelsen, T.5
Brat, D.J.6
Grimsby, J.7
Sougnez, C.8
Muller, F.9
Hu, J.10
-
32
-
-
0030222037
-
Microglia: a sensor for pathological events in the CNS
-
Kreutzberg, G.W., Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19 (1996), 312–318.
-
(1996)
Trends Neurosci.
, vol.19
, pp. 312-318
-
-
Kreutzberg, G.W.1
-
33
-
-
84949008680
-
Recurrent glioblastomas reveal molecular subtypes associated with mechanistic implications of drug-resistance
-
Kwon, S.M., Kang, S.H., Park, C.K., Jung, S., Park, E.S., Lee, J.S., Kim, S.H., Woo, H.G., Recurrent glioblastomas reveal molecular subtypes associated with mechanistic implications of drug-resistance. PLoS One, 10, 2015, e0140528.
-
(2015)
PLoS One
, vol.10
, pp. e0140528
-
-
Kwon, S.M.1
Kang, S.H.2
Park, C.K.3
Jung, S.4
Park, E.S.5
Lee, J.S.6
Kim, S.H.7
Woo, H.G.8
-
34
-
-
65349141187
-
Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas
-
Le, L.Q., Shipman, T., Burns, D.K., Parada, L.F., Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas. Cell Stem Cell 4 (2009), 453–463.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 453-463
-
-
Le, L.Q.1
Shipman, T.2
Burns, D.K.3
Parada, L.F.4
-
35
-
-
85014515130
-
Spatiotemporal genomic architecture informs precision oncology in glioblastoma
-
Lee, J.K., Wang, J., Sa, J.K., Ladewig, E., Lee, H.O., Lee, I.H., Kang, H.J., Rosenbloom, D.S., Camara, P.G., Liu, Z., et al. Spatiotemporal genomic architecture informs precision oncology in glioblastoma. Nat. Genet. 49 (2017), 594–599.
-
(2017)
Nat. Genet.
, vol.49
, pp. 594-599
-
-
Lee, J.K.1
Wang, J.2
Sa, J.K.3
Ladewig, E.4
Lee, H.O.5
Lee, I.H.6
Kang, H.J.7
Rosenbloom, D.S.8
Camara, P.G.9
Liu, Z.10
-
36
-
-
84887083535
-
TCPA: a resource for cancer functional proteomics data
-
Li, J., Lu, Y., Akbani, R., Ju, Z., Roebuck, P.L., Liu, W., Yang, J.Y., Broom, B.M., Verhaak, R.G., Kane, D.W., et al. TCPA: a resource for cancer functional proteomics data. Nat. Methods 10 (2013), 1046–1047.
-
(2013)
Nat. Methods
, vol.10
, pp. 1046-1047
-
-
Li, J.1
Lu, Y.2
Akbani, R.3
Ju, Z.4
Roebuck, P.L.5
Liu, W.6
Yang, J.Y.7
Broom, B.M.8
Verhaak, R.G.9
Kane, D.W.10
-
37
-
-
84930275553
-
Comparison of gene expression patterns across 12 tumor types identifies a cancer supercluster characterized by TP53 mutations and cell cycle defects
-
Martinez, E., Yoshihara, K., Kim, H., Mills, G.M., Trevino, V., Verhaak, R.G., Comparison of gene expression patterns across 12 tumor types identifies a cancer supercluster characterized by TP53 mutations and cell cycle defects. Oncogene 34 (2015), 2732–2740.
-
(2015)
Oncogene
, vol.34
, pp. 2732-2740
-
-
Martinez, E.1
Yoshihara, K.2
Kim, H.3
Mills, G.M.4
Trevino, V.5
Verhaak, R.G.6
-
38
-
-
84942307003
-
DNA methylation and somatic mutations converge on the cell cycle and define similar evolutionary histories in brain tumors
-
Mazor, T., Pankov, A., Johnson, B.E., Hong, C., Hamilton, E.G., Bell, R.J., Smirnov, I.V., Reis, G.F., Phillips, J.J., Barnes, M.J., et al. DNA methylation and somatic mutations converge on the cell cycle and define similar evolutionary histories in brain tumors. Cancer Cell 28 (2015), 307–317.
-
(2015)
Cancer Cell
, vol.28
, pp. 307-317
-
-
Mazor, T.1
Pankov, A.2
Johnson, B.E.3
Hong, C.4
Hamilton, E.G.5
Bell, R.J.6
Smirnov, I.V.7
Reis, G.F.8
Phillips, J.J.9
Barnes, M.J.10
-
39
-
-
76749106110
-
Blockade of tumor necrosis factor alpha signaling in tumor-associated macrophages as a radiosensitizing strategy
-
Meng, Y., Beckett, M.A., Liang, H., Mauceri, H.J., van Rooijen, N., Cohen, K.S., Weichselbaum, R.R., Blockade of tumor necrosis factor alpha signaling in tumor-associated macrophages as a radiosensitizing strategy. Cancer Res. 70 (2010), 1534–1543.
-
(2010)
Cancer Res.
, vol.70
, pp. 1534-1543
-
-
Meng, Y.1
Beckett, M.A.2
Liang, H.3
Mauceri, H.J.4
van Rooijen, N.5
Cohen, K.S.6
Weichselbaum, R.R.7
-
40
-
-
84928927858
-
Robust enumeration of cell subsets from tissue expression profiles
-
Newman, A.M., Liu, C.L., Green, M.R., Gentles, A.J., Feng, W., Xu, Y., Hoang, C.D., Diehn, M., Alizadeh, A.A., Robust enumeration of cell subsets from tissue expression profiles. Nat. Methods 12 (2015), 453–457.
-
(2015)
Nat. Methods
, vol.12
, pp. 453-457
-
-
Newman, A.M.1
Liu, C.L.2
Green, M.R.3
Gentles, A.J.4
Feng, W.5
Xu, Y.6
Hoang, C.D.7
Diehn, M.8
Alizadeh, A.A.9
-
41
-
-
77952108366
-
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
-
Noushmehr, H., Weisenberger, D.J., Diefes, K., Phillips, H.S., Pujara, K., Berman, B.P., Pan, F., Pelloski, C.E., Sulman, E.P., Bhat, K.P., et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 17 (2010), 510–522.
-
(2010)
Cancer Cell
, vol.17
, pp. 510-522
-
-
Noushmehr, H.1
Weisenberger, D.J.2
Diefes, K.3
Phillips, H.S.4
Pujara, K.5
Berman, B.P.6
Pan, F.7
Pelloski, C.E.8
Sulman, E.P.9
Bhat, K.P.10
-
42
-
-
84890275818
-
Using the molecular classification of glioblastoma to inform personalized treatment
-
Olar, A., Aldape, K.D., Using the molecular classification of glioblastoma to inform personalized treatment. J. Pathol. 232 (2014), 165–177.
-
(2014)
J. Pathol.
, vol.232
, pp. 165-177
-
-
Olar, A.1
Aldape, K.D.2
-
43
-
-
84905675587
-
Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma
-
Ozawa, T., Riester, M., Cheng, Y., Huse, J.T., Squatrito, M., Helmy, K., Charles, N., Michor, F., Holland, E.C., Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma. Cancer Cell 26 (2014), 288–300.
-
(2014)
Cancer Cell
, vol.26
, pp. 288-300
-
-
Ozawa, T.1
Riester, M.2
Cheng, Y.3
Huse, J.T.4
Squatrito, M.5
Helmy, K.6
Charles, N.7
Michor, F.8
Holland, E.C.9
-
44
-
-
84858780815
-
Cancer immunotherapy via dendritic cells
-
Palucka, K., Banchereau, J., Cancer immunotherapy via dendritic cells. Nat. Rev. Cancer 12 (2012), 265–277.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 265-277
-
-
Palucka, K.1
Banchereau, J.2
-
45
-
-
84902668801
-
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
-
Patel, A.P., Tirosh, I., Trombetta, J.J., Shalek, A.K., Gillespie, S.M., Wakimoto, H., Cahill, D.P., Nahed, B.V., Curry, W.T., Martuza, R.L., et al. Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science 344 (2014), 1396–1401.
-
(2014)
Science
, vol.344
, pp. 1396-1401
-
-
Patel, A.P.1
Tirosh, I.2
Trombetta, J.J.3
Shalek, A.K.4
Gillespie, S.M.5
Wakimoto, H.6
Cahill, D.P.7
Nahed, B.V.8
Curry, W.T.9
Martuza, R.L.10
-
46
-
-
84900328038
-
Sailfish enables alignment-free isoform quantification from RNA-seq reads using lightweight algorithms
-
Patro, R., Mount, S.M., Kingsford, C., Sailfish enables alignment-free isoform quantification from RNA-seq reads using lightweight algorithms. Nat. Biotechnol. 32 (2014), 462–464.
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 462-464
-
-
Patro, R.1
Mount, S.M.2
Kingsford, C.3
-
47
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
Phillips, H.S., Kharbanda, S., Chen, R., Forrest, W.F., Soriano, R.H., Wu, T.D., Misra, A., Nigro, J.M., Colman, H., Soroceanu, L., et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 9 (2006), 157–173.
-
(2006)
Cancer Cell
, vol.9
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
Forrest, W.F.4
Soriano, R.H.5
Wu, T.D.6
Misra, A.7
Nigro, J.M.8
Colman, H.9
Soroceanu, L.10
-
48
-
-
79952711945
-
Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapy
-
Prins, R.M., Soto, H., Konkankit, V., Odesa, S.K., Eskin, A., Yong, W.H., Nelson, S.F., Liau, L.M., Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapy. Clin. Cancer Res. 17 (2011), 1603–1615.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 1603-1615
-
-
Prins, R.M.1
Soto, H.2
Konkankit, V.3
Odesa, S.K.4
Eskin, A.5
Yong, W.H.6
Nelson, S.F.7
Liau, L.M.8
-
49
-
-
84887481716
-
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
-
Pyonteck, S.M., Akkari, L., Schuhmacher, A.J., Bowman, R.L., Sevenich, L., Quail, D.F., Olson, O.C., Quick, M.L., Huse, J.T., Teijeiro, V., et al. CSF-1R inhibition alters macrophage polarization and blocks glioma progression. Nat. Med. 19 (2013), 1264–1272.
-
(2013)
Nat. Med.
, vol.19
, pp. 1264-1272
-
-
Pyonteck, S.M.1
Akkari, L.2
Schuhmacher, A.J.3
Bowman, R.L.4
Sevenich, L.5
Quail, D.F.6
Olson, O.C.7
Quick, M.L.8
Huse, J.T.9
Teijeiro, V.10
-
50
-
-
84971538906
-
The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas
-
Quail, D.F., Bowman, R.L., Akkari, L., Quick, M.L., Schuhmacher, A.J., Huse, J.T., Holland, E.C., Sutton, J.C., Joyce, J.A., The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas. Science, 352, 2016, aad3018.
-
(2016)
Science
, vol.352
, pp. aad3018
-
-
Quail, D.F.1
Bowman, R.L.2
Akkari, L.3
Quick, M.L.4
Schuhmacher, A.J.5
Huse, J.T.6
Holland, E.C.7
Sutton, J.C.8
Joyce, J.A.9
-
51
-
-
84902546715
-
Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy
-
Ries, C.H., Cannarile, M.A., Hoves, S., Benz, J., Wartha, K., Runza, V., Rey-Giraud, F., Pradel, L.P., Feuerhake, F., Klaman, I., et al. Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy. Cancer Cell 25 (2014), 846–859.
-
(2014)
Cancer Cell
, vol.25
, pp. 846-859
-
-
Ries, C.H.1
Cannarile, M.A.2
Hoves, S.3
Benz, J.4
Wartha, K.5
Runza, V.6
Rey-Giraud, F.7
Pradel, L.P.8
Feuerhake, F.9
Klaman, I.10
-
52
-
-
84877632013
-
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
-
Rohle, D., Popovici-Muller, J., Palaskas, N., Turcan, S., Grommes, C., Campos, C., Tsoi, J., Clark, O., Oldrini, B., Komisopoulou, E., et al. An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science 340 (2013), 626–630.
-
(2013)
Science
, vol.340
, pp. 626-630
-
-
Rohle, D.1
Popovici-Muller, J.2
Palaskas, N.3
Turcan, S.4
Grommes, C.5
Campos, C.6
Tsoi, J.7
Clark, O.8
Oldrini, B.9
Komisopoulou, E.10
-
53
-
-
84928077532
-
Macrophages and therapeutic resistance in cancer
-
Ruffell, B., Coussens, L.M., Macrophages and therapeutic resistance in cancer. Cancer Cell 27 (2015), 462–472.
-
(2015)
Cancer Cell
, vol.27
, pp. 462-472
-
-
Ruffell, B.1
Coussens, L.M.2
-
54
-
-
33847679625
-
Improved precision and accuracy for microarrays using updated probe set definitions
-
Sandberg, R., Larsson, O., Improved precision and accuracy for microarrays using updated probe set definitions. BMC Bioinformatics, 8, 2007, 48.
-
(2007)
BMC Bioinformatics
, vol.8
, pp. 48
-
-
Sandberg, R.1
Larsson, O.2
-
55
-
-
84928770388
-
Neoantigens in cancer immunotherapy
-
Schumacher, T.N., Schreiber, R.D., Neoantigens in cancer immunotherapy. Science 348 (2015), 69–74.
-
(2015)
Science
, vol.348
, pp. 69-74
-
-
Schumacher, T.N.1
Schreiber, R.D.2
-
56
-
-
84928774156
-
The future of immune checkpoint therapy
-
Sharma, P., Allison, J.P., The future of immune checkpoint therapy. Science 348 (2015), 56–61.
-
(2015)
Science
, vol.348
, pp. 56-61
-
-
Sharma, P.1
Allison, J.P.2
-
57
-
-
84867606428
-
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma
-
Sturm, D., Witt, H., Hovestadt, V., Khuong-Quang, D.A., Jones, D.T., Konermann, C., Pfaff, E., Tonjes, M., Sill, M., Bender, S., et al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 22 (2012), 425–437.
-
(2012)
Cancer Cell
, vol.22
, pp. 425-437
-
-
Sturm, D.1
Witt, H.2
Hovestadt, V.3
Khuong-Quang, D.A.4
Jones, D.T.5
Konermann, C.6
Pfaff, E.7
Tonjes, M.8
Sill, M.9
Bender, S.10
-
58
-
-
84894573670
-
Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge
-
Sturm, D., Bender, S., Jones, D.T., Lichter, P., Grill, J., Becher, O., Hawkins, C., Majewski, J., Jones, C., Costello, J.F., et al. Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge. Nat. Rev. Cancer 14 (2014), 92–107.
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 92-107
-
-
Sturm, D.1
Bender, S.2
Jones, D.T.3
Lichter, P.4
Grill, J.5
Becher, O.6
Hawkins, C.7
Majewski, J.8
Jones, C.9
Costello, J.F.10
-
59
-
-
84975241222
-
Human glioblastoma-associated microglia/monocytes express a distinct RNA profile compared to human control and murine samples
-
Szulzewsky, F., Arora, S., de Witte, L., Ulas, T., Markovic, D., Schultze, J.L., Holland, E.C., Synowitz, M., Wolf, S.A., Kettenmann, H., Human glioblastoma-associated microglia/monocytes express a distinct RNA profile compared to human control and murine samples. Glia 64 (2016), 1416–1436.
-
(2016)
Glia
, vol.64
, pp. 1416-1436
-
-
Szulzewsky, F.1
Arora, S.2
de Witte, L.3
Ulas, T.4
Markovic, D.5
Schultze, J.L.6
Holland, E.C.7
Synowitz, M.8
Wolf, S.A.9
Kettenmann, H.10
-
60
-
-
84904994551
-
PRADA: pipeline for RNA sequencing data analysis
-
Torres-Garcia, W., Zheng, S., Sivachenko, A., Vegesna, R., Wang, Q., Yao, R., Berger, M.F., Weinstein, J.N., Getz, G., Verhaak, R.G., PRADA: pipeline for RNA sequencing data analysis. Bioinformatics 30 (2014), 2224–2226.
-
(2014)
Bioinformatics
, vol.30
, pp. 2224-2226
-
-
Torres-Garcia, W.1
Zheng, S.2
Sivachenko, A.3
Vegesna, R.4
Wang, Q.5
Yao, R.6
Berger, M.F.7
Weinstein, J.N.8
Getz, G.9
Verhaak, R.G.10
-
61
-
-
84936762102
-
Changes in the EGFR amplification and EGFRvIII expression between paired primary and recurrent glioblastomas
-
van den Bent, M.J., Gao, Y., Kerkhof, M., Kros, J.M., Gorlia, T., van Zwieten, K., Prince, J., van Duinen, S., Sillevis Smitt, P.A., Taphoorn, M., French, P.J., Changes in the EGFR amplification and EGFRvIII expression between paired primary and recurrent glioblastomas. Neuro Oncol. 17 (2015), 935–941.
-
(2015)
Neuro Oncol.
, vol.17
, pp. 935-941
-
-
van den Bent, M.J.1
Gao, Y.2
Kerkhof, M.3
Kros, J.M.4
Gorlia, T.5
van Zwieten, K.6
Prince, J.7
van Duinen, S.8
Sillevis Smitt, P.A.9
Taphoorn, M.10
French, P.J.11
-
62
-
-
0036632353
-
Changes in blood-brain barrier permeability induced by radiotherapy: implications for timing of chemotherapy? (Review)
-
van Vulpen, M., Kal, H.B., Taphoorn, M.J., El-Sharouni, S.Y., Changes in blood-brain barrier permeability induced by radiotherapy: implications for timing of chemotherapy? (Review). Oncol. Rep. 9 (2002), 683–688.
-
(2002)
Oncol. Rep.
, vol.9
, pp. 683-688
-
-
van Vulpen, M.1
Kal, H.B.2
Taphoorn, M.J.3
El-Sharouni, S.Y.4
-
63
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak, R.G., Hoadley, K.A., Purdom, E., Wang, V., Qi, Y., Wilkerson, M.D., Miller, C.R., Ding, L., Golub, T., Mesirov, J.P., et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17 (2010), 98–110.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
Wilkerson, M.D.6
Miller, C.R.7
Ding, L.8
Golub, T.9
Mesirov, J.P.10
-
64
-
-
75249095274
-
DEGseq: an R package for identifying differentially expressed genes from RNA-seq data
-
Wang, L., Feng, Z., Wang, X., Wang, X., Zhang, X., DEGseq: an R package for identifying differentially expressed genes from RNA-seq data. Bioinformatics 26 (2010), 136–138.
-
(2010)
Bioinformatics
, vol.26
, pp. 136-138
-
-
Wang, L.1
Feng, Z.2
Wang, X.3
Wang, X.4
Zhang, X.5
-
65
-
-
84904856334
-
Effect of miR-142-3p on the M2 macrophage and therapeutic efficacy against murine glioblastoma
-
Xu, S., Wei, J., Wang, F., Kong, L.Y., Ling, X.Y., Nduom, E., Gabrusiewicz, K., Doucette, T., Yang, Y., Yaghi, N.K., et al. Effect of miR-142-3p on the M2 macrophage and therapeutic efficacy against murine glioblastoma. J. Natl. Cancer Inst., 106, 2014, 10.1093/jnci/dju162.
-
(2014)
J. Natl. Cancer Inst.
, vol.106
-
-
Xu, S.1
Wei, J.2
Wang, F.3
Kong, L.Y.4
Ling, X.Y.5
Nduom, E.6
Gabrusiewicz, K.7
Doucette, T.8
Yang, Y.9
Yaghi, N.K.10
-
66
-
-
84939440156
-
FGL2 as a multimodality regulator of tumor-mediated immune suppression and therapeutic target in gliomas
-
Yan, J., Kong, L.Y., Hu, J., Gabrusiewicz, K., Dibra, D., Xia, X., Heimberger, A.B., Li, S., FGL2 as a multimodality regulator of tumor-mediated immune suppression and therapeutic target in gliomas. J. Natl. Cancer Inst., 107, 2015, 10.1093/jnci/djv137.
-
(2015)
J. Natl. Cancer Inst.
, vol.107
-
-
Yan, J.1
Kong, L.Y.2
Hu, J.3
Gabrusiewicz, K.4
Dibra, D.5
Xia, X.6
Heimberger, A.B.7
Li, S.8
-
67
-
-
84862879740
-
Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-beta1 signaling pathway
-
Ye, X.Z., Xu, S.L., Xin, Y.H., Yu, S.C., Ping, Y.F., Chen, L., Xiao, H.L., Wang, B., Yi, L., Wang, Q.L., et al. Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-beta1 signaling pathway. J. Immunol. 189 (2012), 444–453.
-
(2012)
J. Immunol.
, vol.189
, pp. 444-453
-
-
Ye, X.Z.1
Xu, S.L.2
Xin, Y.H.3
Yu, S.C.4
Ping, Y.F.5
Chen, L.6
Xiao, H.L.7
Wang, B.8
Yi, L.9
Wang, Q.L.10
-
68
-
-
84885673911
-
Inferring tumour purity and stromal and immune cell admixture from expression data
-
Yoshihara, K., Shahmoradgoli, M., Martinez, E., Vegesna, R., Kim, H., Torres-Garcia, W., Trevino, V., Shen, H., Laird, P.W., Levine, D.A., et al. Inferring tumour purity and stromal and immune cell admixture from expression data. Nat. Commun., 4, 2013, 2612.
-
(2013)
Nat. Commun.
, vol.4
, pp. 2612
-
-
Yoshihara, K.1
Shahmoradgoli, M.2
Martinez, E.3
Vegesna, R.4
Kim, H.5
Torres-Garcia, W.6
Trevino, V.7
Shen, H.8
Laird, P.W.9
Levine, D.A.10
-
69
-
-
84877581852
-
Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas
-
Zeng, J., See, A.P., Phallen, J., Jackson, C.M., Belcaid, Z., Ruzevick, J., Durham, N., Meyer, C., Harris, T.J., Albesiano, E., et al. Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas. Int. J. Radiat. Oncol. Biol. Phys. 86 (2013), 343–349.
-
(2013)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.86
, pp. 343-349
-
-
Zeng, J.1
See, A.P.2
Phallen, J.3
Jackson, C.M.4
Belcaid, Z.5
Ruzevick, J.6
Durham, N.7
Meyer, C.8
Harris, T.J.9
Albesiano, E.10
-
70
-
-
84953709732
-
Purification and characterization of progenitor and mature human astrocytes reveals transcriptional and functional differences with mouse
-
Zhang, Y., Sloan, S.A., Clarke, L.E., Caneda, C., Plaza, C.A., Blumenthal, P.D., Vogel, H., Steinberg, G.K., Edwards, M.S., Li, G., et al. Purification and characterization of progenitor and mature human astrocytes reveals transcriptional and functional differences with mouse. Neuron 89 (2016), 37–53.
-
(2016)
Neuron
, vol.89
, pp. 37-53
-
-
Zhang, Y.1
Sloan, S.A.2
Clarke, L.E.3
Caneda, C.4
Plaza, C.A.5
Blumenthal, P.D.6
Vogel, H.7
Steinberg, G.K.8
Edwards, M.S.9
Li, G.10
-
71
-
-
84856722847
-
Studying a complex tumor: potential and pitfalls
-
Zheng, S., Chheda, M.G., Verhaak, R.G., Studying a complex tumor: potential and pitfalls. Cancer J. 18 (2012), 107–114.
-
(2012)
Cancer J.
, vol.18
, pp. 107-114
-
-
Zheng, S.1
Chheda, M.G.2
Verhaak, R.G.3
|