Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth

Cell

Volumn 167, Issue 5, 2016, Pages 1281-1295.e18

  Hu, Baoli ^a   Wang, Qianghu ^a   Wang, Y Alan ^a   Hua, Sujun ^a   Sauvé, Charles Etienne Gabriel ^a   Ong, Derrick ^a   Lan, Zheng D ^a   Chang, Qing ^a   Ho, Yan Wing ^a   Monasterio, Marta Moreno ^a   Lu, Xin ^a   Zhong, Yi ^a   Zhang, Jianhua ^a   Deng, Pingna ^a   Tan, Zhi ^a   Wang, Guocan ^a   Liao, Wen Ting ^a   Corley, Lynda J ^a   Yan, Haiyan ^b   Zhang, Junxia ^c   You, Yongping ^c   Liu, Ning ^c   Cai, Linbo ^d   Finocchiaro, Gaetano ^e   Phillips, Joanna J ^f   Berger, Mitchel S ^g   Spring, Denise J ^a   Hu, Jian ^a   Sulman, Erik P ^a   Fuller, Gregory N ^a   Chin, Lynda ^a   Verhaak, Roeland G W ^a   DePinho, Ronald A ^a   more..

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^d Guangdong 999 Brain Hospital   (China)

^e DEPARTMENT OF NEUROSURGERY   (Italy)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

cancer stem cell differentiation; glioblastoma; recurrence; tumor microenvironment

Indexed keywords

ANGIOPOIETIN RECEPTOR; CD133 ANTIGEN; CD31 ANTIGEN; CD34 ANTIGEN; ENDOGLIN; PROTEIN KINASE B; TRANSCRIPTION FACTOR DLX5; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR SOX2; VASCULAR ENDOTHELIAL CADHERIN; VASCULOTROPIN RECEPTOR 2; VON WILLEBRAND FACTOR; WNT5A PROTEIN; DLX5 PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; PAX6 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; WNT5A PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CANCER GROWTH; CANCER STEM CELL; CELL DIFFERENTIATION; CLINICAL STUDY; CONTROLLED STUDY; ENDOTHELIUM CELL; EPIGENETICS; GENE EXPRESSION; GLIOBLASTOMA; GLIOBLASTOMA STEM CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR RECURRENCE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEURAL STEM CELL; PATHOLOGY; TUMOR INVASION;

ENDOTHELIAL CELLS; EPIGENOMICS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HOMEODOMAIN PROTEINS; HUMANS; NEOPLASM INVASIVENESS; NEURAL STEM CELLS; PAX6 TRANSCRIPTION FACTOR; PROTO-ONCOGENE PROTEINS C-AKT; TRANSCRIPTION FACTORS; WNT-5A PROTEIN;

EID: 84995893096     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.10.039     Document Type: Article

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