Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation

Cell Reports

Volumn 20, Issue 5, 2017, Pages 1215-1228

  Mohammed, Hisham ^a   Hernando Herraez, Irene ^a   Savino, Aurora ^a   Scialdone, Antonio ^b,c   Macaulay, Iain ^c,f   Mulas, Carla ^d   Chandra, Tamir ^a,g   Voet, Thierry ^c,e   Dean, Wendy ^a   Nichols, Jennifer ^d   Marioni, John C ^b,c,d   Reik, Wolf ^a,c,d  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b EUROPEAN BIOINFORMATICS INSTITUTE   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e UNIVERSITY OF LEUVEN   (Belgium)

^f NORWICH RESEARCH PARK   (United Kingdom)

^g UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

embryo; epiblast; gastrulation; primitive endoderm; primitive streak; single cell RNA seq; transcriptional noise; X chromosome

Indexed keywords

ANIMAL CELL; ARTICLE; CELL CYCLE G1 PHASE; CELL FATE; CELL LINEAGE; CELL PROLIFERATION; CELL SIZE; CELL STRUCTURE; CONTROLLED STUDY; ECTODERM; EMBRYO; GASTRULATION; GENE; GENE EXPRESSION; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; RNA SEQUENCE; SINGLE CELL ANALYSIS; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS; X CHROMOSOME; ZFP57 GENE; ANIMAL; CYTOLOGY; EMBRYOLOGY; GASTRULA; GENETIC TRANSCRIPTION; MAMMALIAN EMBRYO; PHYSIOLOGY;

ANIMALS; CELL PROLIFERATION; EMBRYO, MAMMALIAN; GASTRULA; GASTRULATION; MICE; TRANSCRIPTION, GENETIC;

EID: 85026887626     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.07.009     Document Type: Article

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