메뉴 건너뛰기




Volumn 5, Issue MAR, 2017, Pages

Bioengineering approaches to mature human pluripotent stem cell-derived cardiomyocytes

Author keywords

Biomaterials; Cardiac regeneration; Cardiomyocytes; Cell therapy; Electrical stimulation; Mechanical stimulation; Stem cell

Indexed keywords


EID: 85026843668     PISSN: None     EISSN: 2296634X     Source Type: Journal    
DOI: 10.3389/fcell.2017.00019     Document Type: Short Survey
Times cited : (26)

References (80)
  • 1
    • 34248593790 scopus 로고    scopus 로고
    • Cardiac myocyte cell cycle control in development, disease, and regeneration
    • Ahuja, P., Sdek, P., and Maclellan, W. R. (2007). Cardiac myocyte cell cycle control in development, disease, and regeneration. Physiol. Rev. 87, 521-544. doi: 10.1152/physrev.00032.2006
    • (2007) Physiol. Rev , vol.87 , pp. 521-544
    • Ahuja, P.1    Sdek, P.2    Maclellan, W.R.3
  • 3
    • 0027237887 scopus 로고
    • Alterations of K+ currents in isolated human ventricular myocytes from patients with terminal heart failure
    • Beuckelmann, D. J., Nabauer, M., and Erdmann, E. (1993). Alterations of K+ currents in isolated human ventricular myocytes from patients with terminal heart failure. Circ. Res. 73, 379-385
    • (1993) Circ. Res , vol.73 , pp. 379-385
    • Beuckelmann, D.J.1    Nabauer, M.2    Erdmann, E.3
  • 4
    • 84868125968 scopus 로고    scopus 로고
    • Electrophysiological and contractile function of cardiomyocytes derived from human embryonic stem cells
    • Blazeski, A., Zhu, R., Hunter, D. W., Weinberg, S. H., Boheler, K. R., Zambidis, E. T., et al. (2012). Electrophysiological and contractile function of cardiomyocytes derived from human embryonic stem cells. Prog. Biophys. Mol. Biol. 110, 178-195. doi: 10.1016/j.pbiomolbio.2012.07.012
    • (2012) Prog. Biophys. Mol. Biol , vol.110 , pp. 178-195
    • Blazeski, A.1    Zhu, R.2    Hunter, D.W.3    Weinberg, S.H.4    Boheler, K.R.5    Zambidis, E.T.6
  • 5
    • 0038380259 scopus 로고    scopus 로고
    • T-tubule function in mammalian cardiac myocytes
    • Brette, F., and Orchard, C. (2003). T-tubule function in mammalian cardiac myocytes. Circ. Res. 92, 1182-1192. doi: 10.1161/01.RES.0000074908.17214.FD
    • (2003) Circ. Res , vol.92 , pp. 1182-1192
    • Brette, F.1    Orchard, C.2
  • 6
    • 55649098531 scopus 로고    scopus 로고
    • Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes
    • Cao, F., Wagner, R. A., Wilson, K. D., Xie, X., Fu, J. D., Drukker, M., et al. (2008). Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes. PLoS ONE 3:e3474. doi: 10.1371/journal.pone.0003474
    • (2008) PLoS ONE , vol.3
    • Cao, F.1    Wagner, R.A.2    Wilson, K.D.3    Xie, X.4    Fu, J.D.5    Drukker, M.6
  • 7
    • 60149107033 scopus 로고    scopus 로고
    • In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes
    • Caspi, O., Itzhaki, I., Kehat, I., Gepstein, A., Arbel, G., Huber, I., et al. (2009). In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes. Stem Cells Dev. 18, 161-172. doi: 10.1089/scd.2007.0280
    • (2009) Stem Cells Dev , vol.18 , pp. 161-172
    • Caspi, O.1    Itzhaki, I.2    Kehat, I.3    Gepstein, A.4    Arbel, G.5    Huber, I.6
  • 8
    • 84890462515 scopus 로고    scopus 로고
    • Electrical stimulation promotes maturation of cardiomyocytes derived from human embryonic stem cells
    • Chan, Y. C., Ting, S., Lee, Y. K., Ng, K. M., Zhang, J., Chen, Z., et al. (2013). Electrical stimulation promotes maturation of cardiomyocytes derived from human embryonic stem cells. J. Cardiovasc. Transl. Res. 6, 989-999. doi: 10.1007/s12265-013-9510-z
    • (2013) J. Cardiovasc. Transl. Res , vol.6 , pp. 989-999
    • Chan, Y.C.1    Ting, S.2    Lee, Y.K.3    Ng, K.M.4    Zhang, J.5    Chen, Z.6
  • 9
    • 73349097859 scopus 로고    scopus 로고
    • Electrophysiological challenges of cell-based myocardial repair
    • Chen, H. S., Kim, C., and Mercola, M. (2009). Electrophysiological challenges of cell-based myocardial repair. Circulation 120, 2496-2508. doi: 10.1161/CIRCULATIONAHA.107.751412
    • (2009) Circulation , vol.120 , pp. 2496-2508
    • Chen, H.S.1    Kim, C.2    Mercola, M.3
  • 10
    • 84902312015 scopus 로고    scopus 로고
    • Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts
    • Chong, J. J., Yang, X., Don, C. W., Minami, E., Liu, Y. W., Weyers, J. J., et al. (2014). Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts. Nature 510, 273-277. doi: 10.1038/nature13233
    • (2014) Nature , vol.510 , pp. 273-277
    • Chong, J.J.1    Yang, X.2    Don, C.W.3    Minami, E.4    Liu, Y.W.5    Weyers, J.J.6
  • 11
    • 84877039547 scopus 로고    scopus 로고
    • Identification and characterization of a transient outward K+ current in human induced pluripotent stem cell-derived cardiomyocytes
    • Cordeiro, J. M., Nesterenko, V. V., Sicouri, S., Goodrow, R. J. Jr., Treat, J. A., Desai, M., et al. (2013). Identification and characterization of a transient outward K+ current in human induced pluripotent stem cell-derived cardiomyocytes. J. Mol. Cell. Cardiol. 60, 36-46. doi: 10.1016/j.yjmcc.2013.03.014
    • (2013) J. Mol. Cell. Cardiol , vol.60 , pp. 36-46
    • Cordeiro, J.M.1    Nesterenko, V.V.2    Sicouri, S.3    Goodrow, R.J.4    Treat, J.A.5    Desai, M.6
  • 13
    • 0029023244 scopus 로고
    • Electrophysiologic characteristics of cells spanning the left ventricular wall of human heart: evidence for presence of M cells
    • Drouin, E., Charpentier, F., Gauthier, C., Laurent, K., and Le Marec, H. (1995). Electrophysiologic characteristics of cells spanning the left ventricular wall of human heart: evidence for presence of M cells. J. Am. Coll. Cardiol. 26, 185-192
    • (1995) J. Am. Coll. Cardiol , vol.26 , pp. 185-192
    • Drouin, E.1    Charpentier, F.2    Gauthier, C.3    Laurent, K.4    Le Marec, H.5
  • 14
    • 4644287428 scopus 로고    scopus 로고
    • Force-frequency relationship in intact mammalian ventricular myocardium: physiological and pathophysiological relevance
    • Endoh, M. (2004). Force-frequency relationship in intact mammalian ventricular myocardium: physiological and pathophysiological relevance. Eur. J. Pharmacol. 500, 73-86. doi: 10.1016/j.ejphar.2004.07.013
    • (2004) Eur. J. Pharmacol , vol.500 , pp. 73-86
    • Endoh, M.1
  • 15
    • 84955589449 scopus 로고    scopus 로고
    • Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes
    • Eng, G., Lee, B. W., Protas, L., Gagliardi, M., Brown, K., Kass, R. S., et al. (2016). Autonomous beating rate adaptation in human stem cell-derived cardiomyocytes. Nat. Commun. 7:10312. doi: 10.1038/ncomms10312
    • (2016) Nat. Commun , vol.7 , pp. 10312
    • Eng, G.1    Lee, B.W.2    Protas, L.3    Gagliardi, M.4    Brown, K.5    Kass, R.S.6
  • 16
    • 70149105270 scopus 로고    scopus 로고
    • Impact of dihydrotestosterone on L-type calcium channels in human ventricular cardiomyocytes
    • Er, F., Gassanov, N., Brandt, M. C., Madershahian, N., and Hoppe, U. C. (2009). Impact of dihydrotestosterone on L-type calcium channels in human ventricular cardiomyocytes. Endocr. Res. 34, 59-67. doi: 10.1080/07435800903136953
    • (2009) Endocr. Res , vol.34 , pp. 59-67
    • Er, F.1    Gassanov, N.2    Brandt, M.C.3    Madershahian, N.4    Hoppe, U.C.5
  • 17
    • 84892429611 scopus 로고    scopus 로고
    • The disease-specific phenotype in cardiomyocytes derived from induced pluripotent stem cells of two long QT syndrome type 3 patients
    • Fatima, A., Kaifeng, S., Dittmann, S., Xu, G., Gupta, M. K., Linke, M., et al. (2013). The disease-specific phenotype in cardiomyocytes derived from induced pluripotent stem cells of two long QT syndrome type 3 patients. PLoS ONE 8:e83005. doi: 10.1371/journal.pone.0083005
    • (2013) PLoS ONE , vol.8
    • Fatima, A.1    Kaifeng, S.2    Dittmann, S.3    Xu, G.4    Gupta, M.K.5    Linke, M.6
  • 18
    • 79151484284 scopus 로고    scopus 로고
    • Modulation of human embryonic stem cell-derived cardiomyocyte growth: a testbed for studying human cardiac hypertrophy?
    • Foldes, G., Mioulane, M., Wright, J. S., Liu, A. Q., Novak, P., Merkely, B., et al. (2011). Modulation of human embryonic stem cell-derived cardiomyocyte growth: a testbed for studying human cardiac hypertrophy? J. Mol. Cell. Cardiol. 50, 367-376. doi: 10.1016/j.yjmcc.2010.10.029
    • (2011) J. Mol. Cell. Cardiol , vol.50 , pp. 367-376
    • Foldes, G.1    Mioulane, M.2    Wright, J.S.3    Liu, A.Q.4    Novak, P.5    Merkely, B.6
  • 19
    • 77954184512 scopus 로고    scopus 로고
    • Na+/Ca2+ exchanger is a determinant of excitation-contraction coupling in human embryonic stem cell-derived ventricular cardiomyocytes
    • Fu, J. D., Jiang, P., Rushing, S., Liu, J., Chiamvimonvat, N., and Li, R. A. (2010). Na+/Ca2+ exchanger is a determinant of excitation-contraction coupling in human embryonic stem cell-derived ventricular cardiomyocytes. Stem Cells Dev. 19, 773-782. doi: 10.1089/scd.2009.0184
    • (2010) Stem Cells Dev , vol.19 , pp. 773-782
    • Fu, J.D.1    Jiang, P.2    Rushing, S.3    Liu, J.4    Chiamvimonvat, N.5    Li, R.A.6
  • 20
    • 81155134381 scopus 로고    scopus 로고
    • Distinct roles of microRNA-1 and-499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes
    • Fu, J. D., Rushing, S. N., Lieu, D. K., Chan, C. W., Kong, C. W., Geng, L., et al. (2011). Distinct roles of microRNA-1 and-499 in ventricular specification and functional maturation of human embryonic stem cell-derived cardiomyocytes. PLoS ONE 6:e27417. doi: 10.1371/journal.pone.0027417
    • (2011) PLoS ONE , vol.6
    • Fu, J.D.1    Rushing, S.N.2    Lieu, D.K.3    Chan, C.W.4    Kong, C.W.5    Geng, L.6
  • 21
    • 0026693383 scopus 로고
    • Structural remodeling of cardiac myocytes in patients with ischemic cardiomyopathy
    • Gerdes, A. M., Kellerman, S. E., Moore, J. A., Muffly, K. E., Clark, L. C., Reaves, P. Y., et al. (1992). Structural remodeling of cardiac myocytes in patients with ischemic cardiomyopathy. Circulation 86, 426-430
    • (1992) Circulation , vol.86 , pp. 426-430
    • Gerdes, A.M.1    Kellerman, S.E.2    Moore, J.A.3    Muffly, K.E.4    Clark, L.C.5    Reaves, P.Y.6
  • 22
    • 80054935074 scopus 로고    scopus 로고
    • Cardiomyocytes derived from human embryonic and induced pluripotent stem cells: comparative ultrastructure
    • Gherghiceanu, M., Barad, L., Novak, A., Reiter, I., Itskovitz-Eldor, J., Binah, O., et al. (2011). Cardiomyocytes derived from human embryonic and induced pluripotent stem cells: comparative ultrastructure. J. Cell. Mol. Med. 15, 2539-2551. doi: 10.1111/j.1582-4934.2011.01417.x
    • (2011) J. Cell. Mol. Med , vol.15 , pp. 2539-2551
    • Gherghiceanu, M.1    Barad, L.2    Novak, A.3    Reiter, I.4    Itskovitz-Eldor, J.5    Binah, O.6
  • 23
    • 0021846419 scopus 로고
    • Linearity of the Frank-Starling relationship in the intact heart: the concept of preload recruitable stroke work
    • Glower, D. D., Spratt, J. A., Snow, N. D., Kabas, J. S., Davis, J. W., Olsen, C. O., et al. (1985). Linearity of the Frank-Starling relationship in the intact heart: the concept of preload recruitable stroke work. Circulation 71, 994-1009
    • (1985) Circulation , vol.71 , pp. 994-1009
    • Glower, D.D.1    Spratt, J.A.2    Snow, N.D.3    Kabas, J.S.4    Davis, J.W.5    Olsen, C.O.6
  • 24
    • 84896544312 scopus 로고    scopus 로고
    • Temporal impact of substrate mechanics on differentiation of human embryonic stem cells to cardiomyocytes
    • Hazeltine, L. B., Badur, M. G., Lian, X., Das, A., Han, W., and Palecek, S. P. (2014). Temporal impact of substrate mechanics on differentiation of human embryonic stem cells to cardiomyocytes. Acta Biomater. 10, 604-612. doi: 10.1016/j.actbio.2013.10.033
    • (2014) Acta Biomater , vol.10 , pp. 604-612
    • Hazeltine, L.B.1    Badur, M.G.2    Lian, X.3    Das, A.4    Han, W.5    Palecek, S.P.6
  • 25
    • 84862282455 scopus 로고    scopus 로고
    • Effects of substrate mechanics on contractility of cardiomyocytes generated from human pluripotent stem cells
    • Hazeltine, L. B., Simmons, C. S., Salick, M. R., Lian, X., Badur, M. G., Han, W., et al. (2012). Effects of substrate mechanics on contractility of cardiomyocytes generated from human pluripotent stem cells. Int. J. Cell Biol. 2012:508294. doi: 10.1155/2012/508294
    • (2012) Int. J. Cell Biol , vol.2012
    • Hazeltine, L.B.1    Simmons, C.S.2    Salick, M.R.3    Lian, X.4    Badur, M.G.5    Han, W.6
  • 26
    • 0038300672 scopus 로고    scopus 로고
    • Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization
    • He, J. Q., Ma, Y., Lee, Y., Thomson, J. A., and Kamp, T. J. (2003). Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization. Circ. Res. 93, 32-39. doi: 10.1161/01.RES.0000080317.92718.99
    • (2003) Circ. Res , vol.93 , pp. 32-39
    • He, J.Q.1    Ma, Y.2    Lee, Y.3    Thomson, J.A.4    Kamp, T.J.5
  • 27
    • 84904753518 scopus 로고    scopus 로고
    • Functional improvement and maturation of rat and human engineered heart tissue by chronic electrical stimulation
    • Hirt, M. N., Boeddinghaus, J., Mitchell, A., Schaaf, S., Bornchen, C., Muller, C., et al. (2014). Functional improvement and maturation of rat and human engineered heart tissue by chronic electrical stimulation. J. Mol. Cell. Cardiol. 74, 151-161. doi: 10.1016/j.yjmcc.2014.05.009
    • (2014) J. Mol. Cell. Cardiol , vol.74 , pp. 151-161
    • Hirt, M.N.1    Boeddinghaus, J.2    Mitchell, A.3    Schaaf, S.4    Bornchen, C.5    Muller, C.6
  • 28
    • 79953655401 scopus 로고    scopus 로고
    • Calcium handling in human induced pluripotent stem cell derived cardiomyocytes
    • Itzhaki, I., Rapoport, S., Huber, I., Mizrahi, I., Zwi-Dantsis, L., Arbel, G., et al. (2011). Calcium handling in human induced pluripotent stem cell derived cardiomyocytes. PLoS ONE 6:e18037. doi: 10.1371/journal.pone.0018037
    • (2011) PLoS ONE , vol.6
    • Itzhaki, I.1    Rapoport, S.2    Huber, I.3    Mizrahi, I.4    Zwi-Dantsis, L.5    Arbel, G.6
  • 29
    • 84884364320 scopus 로고    scopus 로고
    • Human-induced pluripotent stem cell-derived cardiomyocytes exhibit temporal changes in phenotype
    • Ivashchenko, C. Y., Pipes, G. C., Lozinskaya, I. M., Lin, Z., Xiaoping, X., Needle, S., et al. (2013). Human-induced pluripotent stem cell-derived cardiomyocytes exhibit temporal changes in phenotype. Am. J. Physiol. Heart Circ. Physiol. 305, H913-H922. doi: 10.1152/ajpheart.00819.2012
    • (2013) Am. J. Physiol. Heart Circ. Physiol , vol.305 , pp. H913-H922
    • Ivashchenko, C.Y.1    Pipes, G.C.2    Lozinskaya, I.M.3    Lin, Z.4    Xiaoping, X.5    Needle, S.6
  • 30
    • 84859641526 scopus 로고    scopus 로고
    • Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG
    • Jonsson, M. K., Vos, M. A., Mirams, G. R., Duker, G., Sartipy, P., De Boer, T. P., et al. (2012). Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG. J. Mol. Cell. Cardiol. 52, 998-1008. doi: 10.1016/j.yjmcc.2012.02.002
    • (2012) J. Mol. Cell. Cardiol , vol.52 , pp. 998-1008
    • Jonsson, M.K.1    Vos, M.A.2    Mirams, G.R.3    Duker, G.4    Sartipy, P.5    De Boer, T.P.6
  • 31
    • 57949091458 scopus 로고    scopus 로고
    • Contribution of IKr and IK1 to ventricular repolarization in canine and human myocytes: is there any influence of action potential duration?
    • Jost, N., Acsai, K., Horvath, B., Banyasz, T., Baczko, I., Bitay, M., et al. (2009). Contribution of IKr and IK1 to ventricular repolarization in canine and human myocytes: is there any influence of action potential duration? Basic Res. Cardiol. 104, 33-41. doi: 10.1007/s00395-008-0730-3
    • (2009) Basic Res. Cardiol , vol.104 , pp. 33-41
    • Jost, N.1    Acsai, K.2    Horvath, B.3    Banyasz, T.4    Baczko, I.5    Bitay, M.6
  • 32
    • 77954202607 scopus 로고    scopus 로고
    • Non-cardiomyocytes influence the electrophysiological maturation of human embryonic stem cell-derived cardiomyocytes during differentiation
    • Kim, C., Majdi, M., Xia, P., Wei, K. A., Talantova, M., Spiering, S., et al. (2010). Non-cardiomyocytes influence the electrophysiological maturation of human embryonic stem cell-derived cardiomyocytes during differentiation. Stem Cells Dev. 19, 783-795. doi: 10.1089/scd.2009.0349
    • (2010) Stem Cells Dev , vol.19 , pp. 783-795
    • Kim, C.1    Majdi, M.2    Xia, P.3    Wei, K.A.4    Talantova, M.5    Spiering, S.6
  • 33
    • 84874741888 scopus 로고    scopus 로고
    • Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs
    • Kim, C., Wong, J., Wen, J., Wang, S., Wang, C., Spiering, S., et al. (2013). Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs. Nature 494, 105-110. doi: 10.1038/nature11799
    • (2013) Nature , vol.494 , pp. 105-110
    • Kim, C.1    Wong, J.2    Wen, J.3    Wang, S.4    Wang, C.5    Spiering, S.6
  • 34
    • 65249179464 scopus 로고    scopus 로고
    • Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes
    • Kita-Matsuo, H., Barcova, M., Prigozhina, N., Salomonis, N., Wei, K., Jacot, J. G., et al. (2009). Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes. PLoS ONE 4:e5046. doi: 10.1371/journal.pone.0005046
    • (2009) PLoS ONE , vol.4
    • Kita-Matsuo, H.1    Barcova, M.2    Prigozhina, N.3    Salomonis, N.4    Wei, K.5    Jacot, J.G.6
  • 35
    • 34948891467 scopus 로고    scopus 로고
    • Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
    • Laflamme, M. A., Chen, K. Y., Naumova, A. V., Muskheli, V., Fugate, J. A., Dupras, S. K., et al. (2007). Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat. Biotechnol. 25, 1015-1024. doi: 10.1038/nbt1327
    • (2007) Nat. Biotechnol , vol.25 , pp. 1015-1024
    • Laflamme, M.A.1    Chen, K.Y.2    Naumova, A.V.3    Muskheli, V.4    Fugate, J.A.5    Dupras, S.K.6
  • 36
    • 84862285036 scopus 로고    scopus 로고
    • Simultaneous voltage and calcium mapping of genetically purified human induced pluripotent stem cell-derived cardiac myocyte monolayers
    • Lee, P., Klos, M., Bollensdorff, C., Hou, L., Ewart, P., Kamp, T. J., et al. (2012). Simultaneous voltage and calcium mapping of genetically purified human induced pluripotent stem cell-derived cardiac myocyte monolayers. Circ. Res. 110, 1556-1563. doi: 10.1161/CIRCRESAHA.111.262535
    • (2012) Circ. Res , vol.110 , pp. 1556-1563
    • Lee, P.1    Klos, M.2    Bollensdorff, C.3    Hou, L.4    Ewart, P.5    Kamp, T.J.6
  • 37
    • 0030222165 scopus 로고    scopus 로고
    • Human pediatric and adult ventricular cardiomyocytes in culture: assessment of phenotypic changes with passaging
    • Li, R. K., Mickle, D. A., Weisel, R. D., Carson, S., Omar, S. A., Tumiati, L. C., et al. (1996). Human pediatric and adult ventricular cardiomyocytes in culture: assessment of phenotypic changes with passaging. Cardiovasc. Res. 32, 362-373
    • (1996) Cardiovasc. Res , vol.32 , pp. 362-373
    • Li, R.K.1    Mickle, D.A.2    Weisel, R.D.3    Carson, S.4    Omar, S.A.5    Tumiati, L.C.6
  • 38
    • 84876322089 scopus 로고    scopus 로고
    • Mechanism-based facilitated maturation of human pluripotent stem cell-derived cardiomyocytes
    • Lieu, D. K., Fu, J. D., Chiamvimonvat, N., Tung, K. C., Mcnerney, G. P., Huser, T., et al. (2013). Mechanism-based facilitated maturation of human pluripotent stem cell-derived cardiomyocytes. Circ. Arrhythm. Electrophysiol. 6, 191-201. doi: 10.1161/CIRCEP.111.973420
    • (2013) Circ. Arrhythm. Electrophysiol , vol.6 , pp. 191-201
    • Lieu, D.K.1    Fu, J.D.2    Chiamvimonvat, N.3    Tung, K.C.4    Mcnerney, G.P.5    Huser, T.6
  • 39
    • 84955325728 scopus 로고    scopus 로고
    • The electrophysiological development of cardiomyocytes
    • Liu, J., Laksman, Z., and Backx, P. H. (2016). The electrophysiological development of cardiomyocytes. Adv. Drug Deliv. Rev. 96, 253-273. doi: 10.1016/j.addr.2015.12.023
    • (2016) Adv. Drug Deliv. Rev , vol.96 , pp. 253-273
    • Liu, J.1    Laksman, Z.2    Backx, P.H.3
  • 40
    • 77955980416 scopus 로고    scopus 로고
    • Energy metabolic phenotype of the cardiomyocyte during development, differentiation, and postnatal maturation
    • Lopaschuk, G. D., and Jaswal, J. S. (2010). Energy metabolic phenotype of the cardiomyocyte during development, differentiation, and postnatal maturation. J. Cardiovasc. Pharmacol. 56, 130-140. doi: 10.1097/FJC.0b013e3181e74a14
    • (2010) J. Cardiovasc. Pharmacol , vol.56 , pp. 130-140
    • Lopaschuk, G.D.1    Jaswal, J.S.2
  • 41
    • 84880227000 scopus 로고    scopus 로고
    • Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells
    • Lundy, S. D., Zhu, W. Z., Regnier, M., and Laflamme, M. A. (2013). Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells. Stem Cells Dev. 22, 1991-2002. doi: 10.1089/scd.2012.0490
    • (2013) Stem Cells Dev , vol.22 , pp. 1991-2002
    • Lundy, S.D.1    Zhu, W.Z.2    Regnier, M.3    Laflamme, M.A.4
  • 42
    • 80455164810 scopus 로고    scopus 로고
    • High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents
    • Ma, J., Guo, L., Fiene, S. J., Anson, B. D., Thomson, J. A., Kamp, T. J., et al. (2011). High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents. Am. J. Physiol. Heart Circ. Physiol. 301, H2006-H2017. doi: 10.1152/ajpheart.00694.2011
    • (2011) Am. J. Physiol. Heart Circ. Physiol , vol.301 , pp. H2006-H2017
    • Ma, J.1    Guo, L.2    Fiene, S.J.3    Anson, B.D.4    Thomson, J.A.5    Kamp, T.J.6
  • 43
    • 17744391778 scopus 로고    scopus 로고
    • Effects of endothelin-1 on calcium and potassium currents in undiseased human ventricular myocytes
    • Magyar, J., Iost, N., Kortvely, A., Banyasz, T., Virag, L., Szigligeti, P., et al. (2000). Effects of endothelin-1 on calcium and potassium currents in undiseased human ventricular myocytes. Pflugers Arch. 441, 144-149. doi: 10.1007/s004240000400
    • (2000) Pflugers Arch , vol.441 , pp. 144-149
    • Magyar, J.1    Iost, N.2    Kortvely, A.3    Banyasz, T.4    Virag, L.5    Szigligeti, P.6
  • 44
    • 84895041557 scopus 로고    scopus 로고
    • The effect of cyclic stretch on maturation and 3D tissue formation of human embryonic stem cell-derived cardiomyocytes
    • Mihic, A., Li, J., Miyagi, Y., Gagliardi, M., Li, S.-H., Zu, J., et al. (2014). The effect of cyclic stretch on maturation and 3D tissue formation of human embryonic stem cell-derived cardiomyocytes. Biomaterials 35, 2798-2808. doi: 10.1016/j.biomaterials.2013.12.052
    • (2014) Biomaterials , vol.35 , pp. 2798-2808
    • Mihic, A.1    Li, J.2    Miyagi, Y.3    Gagliardi, M.4    Li, S.-H.5    Zu, J.6
  • 45
    • 0038210217 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells
    • Mummery, C., Ward-Van Oostwaard, D., Doevendans, P., Spijker, R., Van Den Brink, S., Hassink, R., et al. (2003). Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells. Circulation 107, 2733-2740. doi: 10.1161/01.CIR.0000068356.38592.68
    • (2003) Circulation , vol.107 , pp. 2733-2740
    • Mummery, C.1    Ward-Van Oostwaard, D.2    Doevendans, P.3    Spijker, R.4    Van Den Brink, S.5    Hassink, R.6
  • 46
    • 34547099366 scopus 로고    scopus 로고
    • Optical mapping of Langendorff-perfused human hearts: establishing a model for the study of ventricular fibrillation in humans
    • Nanthakumar, K., Jalife, J., Masse, S., Downar, E., Pop, M., Asta, J., et al. (2007). Optical mapping of Langendorff-perfused human hearts: establishing a model for the study of ventricular fibrillation in humans. Am. J. Physiol. Heart Circ. Physiol. 293, H875-H880. doi: 10.1152/ajpheart.01415.2006
    • (2007) Am. J. Physiol. Heart Circ. Physiol , vol.293 , pp. H875-H880
    • Nanthakumar, K.1    Jalife, J.2    Masse, S.3    Downar, E.4    Pop, M.5    Asta, J.6
  • 47
    • 84881480907 scopus 로고    scopus 로고
    • Biowire: a platform for maturation of human pluripotent stem cell-derived cardiomyocytes
    • Nunes, S. S., Miklas, J. W., Liu, J., Aschar-Sobbi, R., Xiao, Y., Zhang, B., et al. (2013). Biowire: a platform for maturation of human pluripotent stem cell-derived cardiomyocytes. Nat. Methods 10, 781-787. doi: 10.1038/nmeth.2524
    • (2013) Nat. Methods , vol.10 , pp. 781-787
    • Nunes, S.S.1    Miklas, J.W.2    Liu, J.3    Aschar-Sobbi, R.4    Xiao, Y.5    Zhang, B.6
  • 48
    • 0030198981 scopus 로고    scopus 로고
    • Aging, cardiac hypertrophy and ischemic cardiomyopathy do not affect the proportion of mononucleated and multinucleated myocytes in the human heart
    • Olivetti, G., Cigola, E., Maestri, R., Corradi, D., Lagrasta, C., Gambert, S. R., et al. (1996). Aging, cardiac hypertrophy and ischemic cardiomyopathy do not affect the proportion of mononucleated and multinucleated myocytes in the human heart. J. Mol. Cell. Cardiol. 28, 1463-1477. doi: 10.1006/jmcc.1996.0137
    • (1996) J. Mol. Cell. Cardiol , vol.28 , pp. 1463-1477
    • Olivetti, G.1    Cigola, E.2    Maestri, R.3    Corradi, D.4    Lagrasta, C.5    Gambert, S.R.6
  • 49
    • 77952253259 scopus 로고    scopus 로고
    • Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: qualitative effects on electrophysiological responses to drugs
    • Otsuji, T. G., Minami, I., Kurose, Y., Yamauchi, K., Tada, M., and Nakatsuji, N. (2010). Progressive maturation in contracting cardiomyocytes derived from human embryonic stem cells: qualitative effects on electrophysiological responses to drugs. Stem Cell Res. 4, 201-213. doi: 10.1016/j.scr.2010.01.002
    • (2010) Stem Cell Res , vol.4 , pp. 201-213
    • Otsuji, T.G.1    Minami, I.2    Kurose, Y.3    Yamauchi, K.4    Tada, M.5    Nakatsuji, N.6
  • 50
    • 84872686794 scopus 로고    scopus 로고
    • The effect of microgrooved culture substrates on calcium cycling of cardiac myocytes derived from human induced pluripotent stem cells
    • Rao, C., Prodromakis, T., Kolker, L., Chaudhry, U. A., Trantidou, T., Sridhar, A., et al. (2013). The effect of microgrooved culture substrates on calcium cycling of cardiac myocytes derived from human induced pluripotent stem cells. Biomaterials 34, 2399-2411. doi: 10.1016/j.biomaterials.2012.11.055
    • (2013) Biomaterials , vol.34 , pp. 2399-2411
    • Rao, C.1    Prodromakis, T.2    Kolker, L.3    Chaudhry, U.A.4    Trantidou, T.5    Sridhar, A.6
  • 51
    • 0033551487 scopus 로고    scopus 로고
    • Survival, integration, and differentiation of cardiomyocyte grafts: a study in normal and injured rat hearts
    • Reinecke, H., Zhang, M., Bartosek, T., and Murry, C. E. (1999). Survival, integration, and differentiation of cardiomyocyte grafts: a study in normal and injured rat hearts. Circulation 100, 193-202
    • (1999) Circulation , vol.100 , pp. 193-202
    • Reinecke, H.1    Zhang, M.2    Bartosek, T.3    Murry, C.E.4
  • 52
    • 84924874555 scopus 로고    scopus 로고
    • Functional maturation of human pluripotent stem cell derived cardiomyocytes in vitro-correlation between contraction force and electrophysiology
    • Ribeiro, M. C., Tertoolen, L. G., Guadix, J. A., Bellin, M., Kosmidis, G., D'aniello, C., et al. (2015). Functional maturation of human pluripotent stem cell derived cardiomyocytes in vitro-correlation between contraction force and electrophysiology. Biomaterials 51, 138-150. doi: 10.1016/j.biomaterials.2015.01.067
    • (2015) Biomaterials , vol.51 , pp. 138-150
    • Ribeiro, M.C.1    Tertoolen, L.G.2    Guadix, J.A.3    Bellin, M.4    Kosmidis, G.5    D'aniello, C.6
  • 53
    • 84876570848 scopus 로고    scopus 로고
    • Concise review: maturation phases of human pluripotent stem cell-derived cardiomyocytes
    • Robertson, C., Tran, D. D., and George, S. C. (2013). Concise review: maturation phases of human pluripotent stem cell-derived cardiomyocytes. Stem Cells 31, 829-837. doi: 10.1002/stem.1331
    • (2013) Stem Cells , vol.31 , pp. 829-837
    • Robertson, C.1    Tran, D.D.2    George, S.C.3
  • 54
    • 84991489701 scopus 로고    scopus 로고
    • Mechanical stress conditioning and electrical stimulation promote contractility and force maturation of induced pluripotent stem cell-derived human cardiac tissue
    • Ruan, J.-L., Tulloch, N. L., Razumova, M. V., Saiget, M., Muskheli, V., Pabon, L., et al. (2016). Mechanical stress conditioning and electrical stimulation promote contractility and force maturation of induced pluripotent stem cell-derived human cardiac tissue. Circulation 134, 1557-1567. doi: 10.1161/CIRCULATIONAHA.114.014998
    • (2016) Circulation , vol.134 , pp. 1557-1567
    • Ruan, J.-L.1    Tulloch, N.L.2    Razumova, M.V.3    Saiget, M.4    Muskheli, V.5    Pabon, L.6
  • 55
    • 84896049344 scopus 로고    scopus 로고
    • Micropattern width dependent sarcomere development in human ESC-derived cardiomyocytes
    • Salick, M. R., Napiwocki, B. N., Sha, J., Knight, G. T., Chindhy, S. A., Kamp, T. J., et al. (2014). Micropattern width dependent sarcomere development in human ESC-derived cardiomyocytes. Biomaterials 35, 4454-4464. doi: 10.1016/j.biomaterials.2014.02.001
    • (2014) Biomaterials , vol.35 , pp. 4454-4464
    • Salick, M.R.1    Napiwocki, B.N.2    Sha, J.3    Knight, G.T.4    Chindhy, S.A.5    Kamp, T.J.6
  • 56
    • 34247580093 scopus 로고    scopus 로고
    • Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach
    • Sartiani, L., Bettiol, E., Stillitano, F., Mugelli, A., Cerbai, E., and Jaconi, M. E. (2007). Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach. Stem Cells 25, 1136-1144. doi: 10.1634/stemcells.2006-0466
    • (2007) Stem Cells , vol.25 , pp. 1136-1144
    • Sartiani, L.1    Bettiol, E.2    Stillitano, F.3    Mugelli, A.4    Cerbai, E.5    Jaconi, M.E.6
  • 57
    • 54249111025 scopus 로고    scopus 로고
    • Calcium handling in human embryonic stem cell-derived cardiomyocytes
    • Satin, J., Itzhaki, I., Rapoport, S., Schroder, E. A., Izu, L., Arbel, G., et al. (2008). Calcium handling in human embryonic stem cell-derived cardiomyocytes. Stem Cells 26, 1961-1972. doi: 10.1634/stemcells.2007-0591
    • (2008) Stem Cells , vol.26 , pp. 1961-1972
    • Satin, J.1    Itzhaki, I.2    Rapoport, S.3    Schroder, E.A.4    Izu, L.5    Arbel, G.6
  • 58
    • 80054783465 scopus 로고    scopus 로고
    • Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology
    • Schaaf, S., Shibamiya, A., Mewe, M., Eder, A., Stohr, A., Hirt, M. N., et al. (2011). Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology. PLoS ONE 6:e26397. doi: 10.1371/journal.pone.0026397
    • (2011) PLoS ONE , vol.6
    • Schaaf, S.1    Shibamiya, A.2    Mewe, M.3    Eder, A.4    Stohr, A.5    Hirt, M.N.6
  • 59
    • 0021910272 scopus 로고
    • Ultrastructural morphometric analysis of myocardium from dogs, rats, hamsters, mice, and from human hearts
    • Schaper, J., Meiser, E., and Stammler, G. (1985). Ultrastructural morphometric analysis of myocardium from dogs, rats, hamsters, mice, and from human hearts. Circ. Res. 56, 377-391
    • (1985) Circ. Res , vol.56 , pp. 377-391
    • Schaper, J.1    Meiser, E.2    Stammler, G.3
  • 60
    • 0142122236 scopus 로고    scopus 로고
    • Barium block of Kir2 and human cardiac inward rectifier currents: evidence for subunit-heteromeric contribution to native currents
    • Schram, G., Pourrier, M., Wang, Z., White, M., and Nattel, S. (2003). Barium block of Kir2 and human cardiac inward rectifier currents: evidence for subunit-heteromeric contribution to native currents. Cardiovasc. Res. 59, 328-338. doi: 10.1016/S0008-6363(03)00366-3
    • (2003) Cardiovasc. Res , vol.59 , pp. 328-338
    • Schram, G.1    Pourrier, M.2    Wang, Z.3    White, M.4    Nattel, S.5
  • 61
    • 0345303845 scopus 로고    scopus 로고
    • Assessment of the ultrastructural and proliferative properties of human embryonic stem cell-derived cardiomyocytes
    • Snir, M., Kehat, I., Gepstein, A., Coleman, R., Itskovitz-Eldor, J., Livne, E., et al. (2003). Assessment of the ultrastructural and proliferative properties of human embryonic stem cell-derived cardiomyocytes. Am. J. Physiol. Heart Circ. Physiol. 285, H2355-H2363. doi: 10.1152/ajpheart.00020.2003
    • (2003) Am. J. Physiol. Heart Circ. Physiol , vol.285 , pp. H2355-H2363
    • Snir, M.1    Kehat, I.2    Gepstein, A.3    Coleman, R.4    Itskovitz-Eldor, J.5    Livne, E.6
  • 62
    • 84883767388 scopus 로고    scopus 로고
    • Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts
    • Streckfuss-Bomeke, K., Wolf, F., Azizian, A., Stauske, M., Tiburcy, M., Wagner, S., et al. (2013). Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts. Eur. Heart J. 34, 2618-2629. doi: 10.1093/eurheartj/ehs203
    • (2013) Eur. Heart J , vol.34 , pp. 2618-2629
    • Streckfuss-Bomeke, K.1    Wolf, F.2    Azizian, A.3    Stauske, M.4    Tiburcy, M.5    Wagner, S.6
  • 63
    • 84949683733 scopus 로고    scopus 로고
    • Biowire platform for maturation of human pluripotent stem cell-derived cardiomyocytes
    • Sun, X., and Nunes, S. S. (2016). Biowire platform for maturation of human pluripotent stem cell-derived cardiomyocytes. Methods 101, 21-26. doi: 10.1016/j.ymeth.2015.11.005
    • (2016) Methods , vol.101 , pp. 21-26
    • Sun, X.1    Nunes, S.S.2
  • 64
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., et al. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872. doi: 10.1016/j.cell.2007.11.019
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6
  • 66
    • 79960023610 scopus 로고    scopus 로고
    • Growth of engineered human myocardium with mechanical loading and vascular coculture
    • Tulloch, N. L., Muskheli, V., Razumova, M. V., Korte, F. S., Regnier, M., Hauch, K. D., et al. (2011). Growth of engineered human myocardium with mechanical loading and vascular coculture. Circ. Res. 109, 47-59. doi: 10.1161/CIRCRESAHA.110.237206
    • (2011) Circ. Res , vol.109 , pp. 47-59
    • Tulloch, N.L.1    Muskheli, V.2    Razumova, M.V.3    Korte, F.S.4    Regnier, M.5    Hauch, K.D.6
  • 67
    • 14744290314 scopus 로고    scopus 로고
    • Increased late sodium current in myocytes from a canine heart failure model and from failing human heart
    • Valdivia, C. R., Chu, W. W., Pu, J., Foell, J. D., Haworth, R. A., Wolff, M. R., et al. (2005). Increased late sodium current in myocytes from a canine heart failure model and from failing human heart. J. Mol. Cell. Cardiol. 38, 475-483. doi: 10.1016/j.yjmcc.2004.12.012
    • (2005) J. Mol. Cell. Cardiol , vol.38 , pp. 475-483
    • Valdivia, C.R.1    Chu, W.W.2    Pu, J.3    Foell, J.D.4    Haworth, R.A.5    Wolff, M.R.6
  • 69
    • 0035110307 scopus 로고    scopus 로고
    • The slow component of the delayed rectifier potassium current in undiseased human ventricular myocytes
    • Virag, L., Iost, N., Opincariu, M., Szolnoky, J., Szecsi, J., Bogats, G., et al. (2001). The slow component of the delayed rectifier potassium current in undiseased human ventricular myocytes. Cardiovasc. Res. 49, 790-797. doi: 10.1016/S0008-6363(00)00306-0
    • (2001) Cardiovasc. Res , vol.49 , pp. 790-797
    • Virag, L.1    Iost, N.2    Opincariu, M.3    Szolnoky, J.4    Szecsi, J.5    Bogats, G.6
  • 70
    • 0242298644 scopus 로고    scopus 로고
    • Dynamic regulation of sodium/calcium exchange function in human heart failure
    • Weber, C. R., Piacentino, V. III., Houser, S. R., and Bers, D. M. (2003). Dynamic regulation of sodium/calcium exchange function in human heart failure. Circulation 108, 2224-2229. doi: 10.1161/01.CIR.0000095274.72486.94
    • (2003) Circulation , vol.108 , pp. 2224-2229
    • Weber, C.R.1    Piacentino, V.2    Houser, S.R.3    Bers, D.M.4
  • 71
    • 0028106771 scopus 로고
    • Transient outward current in human ventricular myocytes of subepicardial and subendocardial origin
    • Wettwer, E., Amos, G. J., Posival, H., and Ravens, U. (1994). Transient outward current in human ventricular myocytes of subepicardial and subendocardial origin. Circ. Res. 75, 473-482
    • (1994) Circ. Res , vol.75 , pp. 473-482
    • Wettwer, E.1    Amos, G.J.2    Posival, H.3    Ravens, U.4
  • 72
    • 70349868345 scopus 로고    scopus 로고
    • Global expression profile of highly enriched cardiomyocytes derived from human embryonic stem cells
    • Xu, X. Q., Soo, S. Y., Sun, W., and Zweigerdt, R. (2009). Global expression profile of highly enriched cardiomyocytes derived from human embryonic stem cells. Stem Cells 27, 2163-2174. doi: 10.1002/stem.166
    • (2009) Stem Cells , vol.27 , pp. 2163-2174
    • Xu, X.Q.1    Soo, S.Y.2    Sun, W.3    Zweigerdt, R.4
  • 73
    • 44349175948 scopus 로고    scopus 로고
    • Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population
    • Yang, L., Soonpaa, M. H., Adler, E. D., Roepke, T. K., Kattman, S. J., Kennedy, M., et al. (2008). Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population. Nature 453, 524-528. doi: 10.1038/nature06894
    • (2008) Nature , vol.453 , pp. 524-528
    • Yang, L.1    Soonpaa, M.H.2    Adler, E.D.3    Roepke, T.K.4    Kattman, S.J.5    Kennedy, M.6
  • 74
    • 84894160639 scopus 로고    scopus 로고
    • Engineering adolescence: maturation of human pluripotent stem cell-derived cardiomyocytes
    • Yang, X., Pabon, L., and Murry, C. E. (2014a). Engineering adolescence: maturation of human pluripotent stem cell-derived cardiomyocytes. Circ. Res. 114, 511-523. doi: 10.1161/CIRCRESAHA.114.300558
    • (2014) Circ. Res , vol.114 , pp. 511-523
    • Yang, X.1    Pabon, L.2    Murry, C.E.3
  • 75
    • 84900335420 scopus 로고    scopus 로고
    • Tri-iodo-l-thyronine promotes the maturation of human cardiomyocytes-derived from induced pluripotent stem cells
    • Yang, X., Rodriguez, M., Pabon, L., Fischer, K. A., Reinecke, H., Regnier, M., et al. (2014b). Tri-iodo-l-thyronine promotes the maturation of human cardiomyocytes-derived from induced pluripotent stem cells. J. Mol. Cell. Cardiol. 72, 296-304. doi: 10.1016/j.yjmcc.2014.04.005
    • (2014) J. Mol. Cell. Cardiol , vol.72 , pp. 296-304
    • Yang, X.1    Rodriguez, M.2    Pabon, L.3    Fischer, K.A.4    Reinecke, H.5    Regnier, M.6
  • 76
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu, J., Vodyanik, M. A., Smuga-Otto, K., Antosiewicz-Bourget, J., Frane, J. L., Tian, S., et al. (2007). Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917-1920. doi: 10.1126/science.1151526
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga-Otto, K.3    Antosiewicz-Bourget, J.4    Frane, J.L.5    Tian, S.6
  • 77
    • 84877794737 scopus 로고    scopus 로고
    • Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes
    • Zhang, D., Shadrin, I. Y., Lam, J., Xian, H. Q., Snodgrass, H. R., and Bursac, N. (2013). Tissue-engineered cardiac patch for advanced functional maturation of human ESC-derived cardiomyocytes. Biomaterials 34, 5813-5820. doi: 10.1016/j.biomaterials.2013.04.026
    • (2013) Biomaterials , vol.34 , pp. 5813-5820
    • Zhang, D.1    Shadrin, I.Y.2    Lam, J.3    Xian, H.Q.4    Snodgrass, H.R.5    Bursac, N.6
  • 78
    • 84988599499 scopus 로고    scopus 로고
    • Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytes
    • Zhu, R., Blazeski, A., Poon, E., Costa, K. D., Tung, L., and Boheler, K. R. (2014). Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytes. Stem Cell Res. Ther. 5, 117. doi: 10.1186/scrt507
    • (2014) Stem Cell Res. Ther , vol.5 , pp. 117
    • Zhu, R.1    Blazeski, A.2    Poon, E.3    Costa, K.D.4    Tung, L.5    Boheler, K.R.6
  • 79
    • 84887909299 scopus 로고    scopus 로고
    • Biomechanical regulation of in vitro cardiogenesis for tissue-engineered heart repair
    • Zimmermann, W. H. (2013). Biomechanical regulation of in vitro cardiogenesis for tissue-engineered heart repair. Stem Cell Res. Ther. 4:137. doi: 10.1186/scrt348
    • (2013) Stem Cell Res. Ther , vol.4 , pp. 137
    • Zimmermann, W.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.