Mechanical Stress Conditioning and Electrical Stimulation Promote Contractility and Force Maturation of Induced Pluripotent Stem Cell-Derived Human Cardiac Tissue

Circulation

Volumn 134, Issue 20, 2016, Pages 1557-1567

  Ruan, Jia Ling ^a   Tulloch, Nathaniel L ^b   Razumova, Maria V ^a,b   Saiget, Mark ^b   Muskheli, Veronica ^b   Pabon, Lil ^b   Reinecke, Hans ^b   Regnier, Michael ^a   Murry, Charles E ^a,b  

^a University of Washington   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

cardiomyocyte hypertrophy; electrical stimulation; human myocardium; stem cell; stress; tissue engineering

Indexed keywords

RYANODINE RECEPTOR 2; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ARTICLE; CELL MATURATION; CELL SIZE; CONTROLLED STUDY; ELECTROSTIMULATION; ENGINEERED HEART TISSUE; EXCITATION CONTRACTION COUPLING; HEART MUSCLE CONTRACTILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; INDUCED PLURIPOTENT STEM CELL; MECHANICAL STIMULATION; MECHANICAL STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RIGIDITY; STARLING LAW; TENSILE STRENGTH; ANIMAL; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; METABOLISM; PHYSIOLOGY; PROCEDURES; TISSUE ENGINEERING;

ANIMALS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MYOCARDIUM; MYOCYTES, CARDIAC; STRESS, MECHANICAL; TISSUE ENGINEERING;

EID: 84991489701     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.114.014998     Document Type: Article

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