The effect of cyclic stretch on maturation and 3D tissue formation of human embryonic stem cell-derived cardiomyocytes

Biomaterials

Volumn 35, Issue 9, 2014, Pages 2798-2808

  Mihic, Anton ^a   Li, Jiao ^a,e   Miyagi, Yasuo ^a   Gagliardi, Mark ^b   Li, Shu Hong ^a   Zu, Jean ^d   Weisel, Richard D ^a,b   Keller, Gordon ^b,c   Li, Ren Ke ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Cardiac tissue engineering; Cardiomyocyte; Human embryonic stem cell; Scaffold; Transplantation; Uniaxial stretch

Indexed keywords

CALCIUM; CELL ENGINEERING; CYTOLOGY; GENES; HEART; POLYMERASE CHAIN REACTION; SCAFFOLDS; STEM CELLS; TISSUE; TRANSPLANTATION (SURGICAL);

CARDIAC ION CHANNELS; CARDIAC TISSUE ENGINEERING; CARDIOMYOCYTES; CONTRACTILE ELEMENTS; HISTOLOGICAL ANALYSIS; HUMAN EMBRYONIC STEM CELLS; UNI-AXIAL STRETCH; UNIAXIAL STRETCHING;

SCAFFOLDS (BIOLOGY);

CALCIUM; GAP JUNCTION PROTEIN; GELATIN; ION CHANNEL; MESSENGER RNA; TISSUE SCAFFOLD; TROPONIN T;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM SIGNALING; CELL ELONGATION; CELL MATURATION; CELL SURVIVAL; CELL ULTRASTRUCTURE; CONTROLLED STUDY; EMBRYONIC STEM CELL; ENGRAFTMENT; EPICARDIUM; GAP JUNCTION; GENE EXPRESSION; HEART; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HISTOLOGY; HUMAN; HUMAN CELL; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; THREE DIMENSIONAL IMAGING; TISSUE ENGINEERING; UNIAXIAL CYCLIC STRETCHING;

RATTUS;

CARDIAC TISSUE ENGINEERING; CARDIOMYOCYTE; HUMAN EMBRYONIC STEM CELL; SCAFFOLD; TRANSPLANTATION; UNIAXIAL STRETCH;

ANIMALS; CALCIUM; CELL DIFFERENTIATION; CELL LINE; CONNEXIN 43; DISEASE MODELS, ANIMAL; EMBRYONIC STEM CELLS; FEASIBILITY STUDIES; GENE EXPRESSION REGULATION; HUMANS; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; RATS, NUDE; STRESS, MECHANICAL; TISSUE ENGINEERING; TISSUE SCAFFOLDS; WOUND HEALING;

EID: 84895041557     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.12.052     Document Type: Article

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