Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens

Cell Death and Disease

Volumn 8, Issue 8, 2017, Pages

  Fernández, Álvaro F ^a,b   Bárcena, Clea ^b   Martínez García, Gemma G ^a,c   Tamargo Gómez, Isaac ^a,b,c   Suárez, María F ^a,c   Pietrocola, Federico ^d,e,f   Castoldi, Francesca ^d,e,f,g   Esteban, Lorena ^h   Sierra Filardi, Elena ^h   Boya, Patricia ^h   López Otín, Carlos ^b   Kroemer, Guido ^d,e,f,i   Mariño, Guillermo ^a,c  

^a INSTITUTO DE INVESTIGACIÓN SANITARIA DEL PRINCIPADO DE ASTURIAS ISPA   (Spain)

^b DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

^c UNIVERSITY OF OVIEDO   (Spain)

^d CENTRE DE RECHERCHE DES CORDELIERS   (France)

^e INSTITUT GUSTAVE ROUSSY   (France)

^f UNIVERSITÉ PARIS DESCARTES   (France)

^g Sotio   (Czech Republic)

^h CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

ⁱ HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; GLUCOSE; INSULIN; LEPTIN; SPERMIDINE; STREPTOZOCIN; ATG4B PROTEIN, MOUSE; AUTOPHAGY RELATED PROTEIN; CYSTEINE PROTEINASE;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CALORIC INTAKE; CELL DEATH; CONTROLLED STUDY; DIABETES MELLITUS; ENERGY EXPENDITURE; FATTY LIVER; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; IMMUNOFLUORESCENCE; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RESPONSE; INSULIN TOLERANCE TEST; INTRAPERITONEAL FAT; LIPOTOXICITY; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; STARVATION; WEIGHT GAIN; WEIGHT REDUCTION; ANIMAL; CHEMICALLY INDUCED; DEFICIENCY; DIET; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY;

ADIPOCYTES; ANIMALS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEINS; CELL DEATH; CYSTEINE ENDOPEPTIDASES; DIABETES MELLITUS, EXPERIMENTAL; DIET; FATTY LIVER; INSULIN-SECRETING CELLS; MICE; MICE, KNOCKOUT; OBESITY;

EID: 85026806719     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2017.373     Document Type: Article

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