Integrated time-lapse and single-cell transcription studies highlight the variable and dynamic nature of human hematopoietic cell fate commitment

PLoS Biology

Volumn 15, Issue 7, 2017, Pages

  Moussy, Alice ^a,b   Cosette, Jérémie ^b   Parmentier, Romuald ^b   da Silva, Cindy ^a   Corre, Guillaume ^b   Richard, Angélique ^c   Gandrillon, Olivier ^c   Stockholm, Daniel ^a   Páldi, András ^a  

^a PSL RESEARCH UNIVERSITY   (France)

^b GÉNÉTHON   (France)

^c UNIVERSITÉ DE LYON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE; CELL FATE; DECISION MAKING; DNA TRANSCRIPTION; GENE EXPRESSION REGULATION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; MORPHOLOGY; PHENOTYPE; TRANSCRIPTION REGULATION; CELL CULTURE; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELL SHAPE; CELL TRACKING; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CYTOLOGY; FETUS BLOOD; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; GENETICS; HEMATOPOIETIC STEM CELL; IMAGE PROCESSING; METABOLISM; MULTIPOTENT STEM CELL; PRINCIPAL COMPONENT ANALYSIS; SINGLE CELL ANALYSIS; TIME LAPSE IMAGING;

BIOLOGICAL MARKER; CD133 ANTIGEN; CD34 ANTIGEN; PROM1 PROTEIN, HUMAN; THY 1 ANTIGEN;

AC133 ANTIGEN; ANTIGENS, CD34; ANTIGENS, THY-1; BIOMARKERS; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELL SHAPE; CELL TRACKING; CELLS, CULTURED; FETAL BLOOD; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEMATOPOIETIC STEM CELLS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MICROSCOPY, CONFOCAL; MULTIPOTENT STEM CELLS; PRINCIPAL COMPONENT ANALYSIS; SINGLE-CELL ANALYSIS; TIME-LAPSE IMAGING; TRANSCRIPTION, GENETIC;

EID: 85026735101     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.2001867     Document Type: Article

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