Local Modulation of Antigen-Presenting Cell Development after Resolution of Pneumonia Induces Long-Term Susceptibility to Secondary Infections

Immunity

Volumn 47, Issue 1, 2017, Pages 135-147.e5

  Roquilly, Antoine ^a,b,c   McWilliam, Hamish E G ^a   Jacqueline, Cedric ^b   Tian, Zehua ^a   Cinotti, Raphael ^b,c   Rimbert, Marie ^d   Wakim, Linda ^a   Caminschi, Irina ^e   Lahoud, Mireille H ^e   Belz, Gabrielle T ^a,f   Kallies, Axel ^a,f   Mintern, Justine D ^g   Asehnoune, Karim ^b,c   Villadangos, Jose A ^a,g  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITÉ DE NANTES   (France)

^c HÔTEL DIEU   (France)

^d NANTES UNIVERSITY HOSPITAL   (France)

^e MONASH UNIVERSITY   (Australia)

^f WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^g UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Bacterial Infection; Dendritic Cells; Influenza Virus; interleukin 12; mucosal immunology; Natural Killer Cells; pneumonia; Transforming Growth Factor Beta; Trauma; Treg cells

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; CD1C ANTIGEN; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 12; MONOCLONAL ANTIBODY; TRANSFORMING GROWTH FACTOR BETA; INTERFERON REGULATORY FACTOR; INTERFERON REGULATORY FACTOR-4; PRDM1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; ARTIFICIAL VENTILATION; BACTERIAL CLEARANCE; BACTERIAL LOAD; BACTERIAL PNEUMONIA; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; DISEASE PREDISPOSITION; DISEASE SEVERITY; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTION; EXPERIMENTAL INJURY; EXPERIMENTAL SEPSIS; FEMALE; GLASGOW COMA SCALE; HUMAN; HUMAN CELL; IMMUNOMODULATION; INFLUENZA A VIRUS; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; LYMPHOCYTE DIFFERENTIATION; MACROPHAGE; MALE; MEDIASTINUM LYMPH NODE; MOUSE; NATURAL KILLER CELL; NONHUMAN; OUTCOME ASSESSMENT; PRIMARY INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SECONDARY INFECTION; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION; TGF BETA SIGNALING; VIRUS PNEUMONIA; AGED; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; GENETICS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MIDDLE AGED; ORTHOMYXOVIRUS INFECTION; PNEUMONIA; SEPSIS;

AGED; ANIMALS; ANTIGEN PRESENTATION; CELL DIFFERENTIATION; CELLS, CULTURED; DENDRITIC CELLS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; HUMANS; IMMUNE TOLERANCE; INFLUENZA A VIRUS; INTERFERON REGULATORY FACTORS; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MIDDLE AGED; ORTHOMYXOVIRIDAE INFECTIONS; PNEUMONIA; SEPSIS; T-LYMPHOCYTES, REGULATORY; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 85026634372     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2017.06.021     Document Type: Article

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